Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
Identifieur interne : 002776 ( Pmc/Corpus ); précédent : 002775; suivant : 002777Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
Auteurs : Nariman Nassiri ; Medi Eslani ; Nekoo Panahi ; Shiva Mehravaran ; Alireza Ziaei ; Ali R. DjalilianSource :
- Journal of Ophthalmic & Vision Research [ 2008-2010 ] ; 2013.
Abstract
Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplantation (allo-SCT). Ocular GVHD develops in approximately 40-60% of patients following allo-SCT and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. Ocular GVHD may lead to severe ocular surface disease, which can significantly diminish quality of life and restrict daily activities. It is thus important to monitor the condition closely since with timely diagnosis, irreversible damage can be avoided. The current review will focus on updated information regarding ocular GVHD.
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PubMed: 24653823
PubMed Central: 3957042
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