Surgical outcome of safe surgery system trabeculectomy combined with cataract extraction
Identifieur interne : 000927 ( Pmc/Checkpoint ); précédent : 000926; suivant : 000928Surgical outcome of safe surgery system trabeculectomy combined with cataract extraction
Auteurs : R R Khandelwal [Inde] ; D. Raje [Inde] ; A. Rathi [Inde] ; A. Agashe [Inde] ; M. Majumdar [Inde] ; R. Khandelwal [Inde]Source :
- Eye [ 0950-222X ] ; 2014.
Abstract
To determine the efficacy of safe surgery system trabeculectomy combined with manual small incision cataract surgery/phacoemulsification in primary glaucoma coexistent with cataract.
This is a retrospective analysis of 105 cases who underwent single-site combined surgery between January 2008 and December 2009. Safe surgery system trabeculectomy with diffuse and posterior application of mitomycin C was performed in all cases. Cataract extraction was done either by Manual Small Incision Cataract Surgery (MSICS) or phacoemulsification. Main outcome measures were success rate of trabeculectomy, as determined by four different IOP goals and incidence of postoperative complications. Analysis was performed using R-2.15, and the significance was tested at 5% level.
The minimum follow-up period was 12 months. The overall success rates (with or without medication) when safe surgery system trabeculectomy was combined with MSICS were 91, 70, and 51% for IOP ≤18, ≤15, and ≤12 mm Hg, respectively, and target IOP was achieved in 72% cases. The mean IOP reduction was 43.8% with MSICS and 42.08% with phacoemulsification. The surgical outcome was not significantly different for both techniques. Postoperative complications were infrequent and comparable.
The Safe Surgery System Trabeculectomy combined with cataract surgery offers excellent IOP control with minimal postoperative complications. It offers an effective and improved solution for primary glaucoma coexistent with cataract found in developing countries.
Url:
DOI: 10.1038/eye.2014.294
PubMed: 25502867
PubMed Central: 4366461
Affiliations:
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Raje</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>MDS Bioanalytics</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rathi, A" sort="Rathi, A" uniqKey="Rathi A" first="A" last="Rathi">A. Rathi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Agashe, A" sort="Agashe, A" uniqKey="Agashe A" first="A" last="Agashe">A. Agashe</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Majumdar, M" sort="Majumdar, M" uniqKey="Majumdar M" first="M" last="Majumdar">M. Majumdar</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Khandelwal, R" sort="Khandelwal, R" uniqKey="Khandelwal R" first="R" last="Khandelwal">R. Khandelwal</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25502867</idno><idno type="pmc">4366461</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366461</idno><idno type="RBID">PMC:4366461</idno><idno type="doi">10.1038/eye.2014.294</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000007</idno><idno type="wicri:Area/Pmc/Curation">000007</idno><idno type="wicri:Area/Pmc/Checkpoint">000927</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Surgical outcome of safe surgery system trabeculectomy combined with cataract extraction</title><author><name sortKey="Khandelwal, R R" sort="Khandelwal, R R" uniqKey="Khandelwal R" first="R R" last="Khandelwal">R R Khandelwal</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Raje, D" sort="Raje, D" uniqKey="Raje D" first="D" last="Raje">D. Raje</name><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>MDS Bioanalytics</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rathi, A" sort="Rathi, A" uniqKey="Rathi A" first="A" last="Rathi">A. Rathi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Agashe, A" sort="Agashe, A" uniqKey="Agashe A" first="A" last="Agashe">A. Agashe</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Majumdar, M" sort="Majumdar, M" uniqKey="Majumdar M" first="M" last="Majumdar">M. Majumdar</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Khandelwal, R" sort="Khandelwal, R" uniqKey="Khandelwal R" first="R" last="Khandelwal">R. Khandelwal</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></nlm:aff><country xml:lang="fr">Inde</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Eye</title><idno type="ISSN">0950-222X</idno><idno type="eISSN">1476-5454</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Purpose</title><p>To determine the efficacy of safe surgery system trabeculectomy combined with manual small incision cataract surgery/phacoemulsification in primary glaucoma coexistent with cataract.</p></sec><sec sec-type="methods"><title>Methods</title><p>This is a retrospective analysis of 105 cases who underwent single-site combined surgery between January 2008 and December 2009. Safe surgery system trabeculectomy with diffuse and posterior application of mitomycin C was performed in all cases. Cataract extraction was done either by Manual Small Incision Cataract Surgery (MSICS) or phacoemulsification. Main outcome measures were success rate of trabeculectomy, as determined by four different IOP goals and incidence of postoperative complications. Analysis was performed using R-2.15, and the significance was tested at 5% level.</p></sec><sec sec-type="results"><title>Results</title><p>The minimum follow-up period was 12 months. The overall success rates (with or without medication) when safe surgery system trabeculectomy was combined with MSICS were 91, 70, and 51% for IOP ≤18, ≤15, and ≤12 mm Hg, respectively, and target IOP was achieved in 72% cases. The mean IOP reduction was 43.8% with MSICS and 42.08% with phacoemulsification. The surgical outcome was not significantly different for both techniques. Postoperative complications were infrequent and comparable.</p></sec><sec sec-type="conclusions"><title>Conclusion</title><p>The Safe Surgery System Trabeculectomy combined with cataract surgery offers excellent IOP control with minimal postoperative complications. It offers an effective and improved solution for primary glaucoma coexistent with cataract found in developing countries.</p></sec></div></front></TEI><pmc article-type="other"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Eye (Lond)</journal-id><journal-id journal-id-type="iso-abbrev">Eye (Lond)</journal-id><journal-title-group><journal-title>Eye</journal-title></journal-title-group><issn pub-type="ppub">0950-222X</issn><issn pub-type="epub">1476-5454</issn><publisher><publisher-name>Nature Publishing Group</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25502867</article-id><article-id pub-id-type="pmc">4366461</article-id><article-id pub-id-type="pii">eye2014294</article-id><article-id pub-id-type="doi">10.1038/eye.2014.294</article-id><article-categories><subj-group subj-group-type="heading"><subject>Clinical Study</subject></subj-group></article-categories><title-group><article-title>Surgical outcome of safe surgery system trabeculectomy combined with cataract extraction</article-title><alt-title alt-title-type="running">Surgical management of cataract coexistent with glaucoma</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Khandelwal</surname><given-names>R R</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="corresp" rid="caf1">*</xref></contrib><contrib contrib-type="author"><name><surname>Raje</surname><given-names>D</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Rathi</surname><given-names>A</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Agashe</surname><given-names>A</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Majumdar</surname><given-names>M</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Khandelwal</surname><given-names>R</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><aff id="aff1"><label>1</label><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Nagpur,<country>India</country></aff><aff id="aff2"><label>2</label><institution>MDS Bioanalytics</institution>, Nagpur,<country>India</country></aff></contrib-group><author-notes><corresp id="caf1"><label>*</label><institution>Department of Ophthalmology, NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital</institution>, Digdoh Hills, Hingna Road, Nagpur 440019, <country>India</country> Tel: +91 7104 306100; Fax: +91 7104 306111. E-mail: <email>rekha.khandelwal@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><month>03</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>12</day><month>12</month><year>2014</year></pub-date><volume>29</volume><issue>3</issue><fpage>363</fpage><lpage>370</lpage><history><date date-type="received"><day>20</day><month>12</month><year>2013</year></date><date date-type="accepted"><day>30</day><month>09</month><year>2014</year></date></history><permissions><copyright-statement>Copyright © 2015 Royal College of Ophthalmologists</copyright-statement><copyright-year>2015</copyright-year><copyright-holder>Royal College of Ophthalmologists</copyright-holder></permissions><abstract><sec><title>Purpose</title><p>To determine the efficacy of safe surgery system trabeculectomy combined with manual small incision cataract surgery/phacoemulsification in primary glaucoma coexistent with cataract.</p></sec><sec sec-type="methods"><title>Methods</title><p>This is a retrospective analysis of 105 cases who underwent single-site combined surgery between January 2008 and December 2009. Safe surgery system trabeculectomy with diffuse and posterior application of mitomycin C was performed in all cases. Cataract extraction was done either by Manual Small Incision Cataract Surgery (MSICS) or phacoemulsification. Main outcome measures were success rate of trabeculectomy, as determined by four different IOP goals and incidence of postoperative complications. Analysis was performed using R-2.15, and the significance was tested at 5% level.</p></sec><sec sec-type="results"><title>Results</title><p>The minimum follow-up period was 12 months. The overall success rates (with or without medication) when safe surgery system trabeculectomy was combined with MSICS were 91, 70, and 51% for IOP ≤18, ≤15, and ≤12 mm Hg, respectively, and target IOP was achieved in 72% cases. The mean IOP reduction was 43.8% with MSICS and 42.08% with phacoemulsification. The surgical outcome was not significantly different for both techniques. Postoperative complications were infrequent and comparable.</p></sec><sec sec-type="conclusions"><title>Conclusion</title><p>The Safe Surgery System Trabeculectomy combined with cataract surgery offers excellent IOP control with minimal postoperative complications. It offers an effective and improved solution for primary glaucoma coexistent with cataract found in developing countries.</p></sec></abstract></article-meta></front></pmc><affiliations><list><country><li>Inde</li></country></list><tree><country name="Inde"><noRegion><name sortKey="Khandelwal, R R" sort="Khandelwal, R R" uniqKey="Khandelwal R" first="R R" last="Khandelwal">R R Khandelwal</name></noRegion><name sortKey="Agashe, A" sort="Agashe, A" uniqKey="Agashe A" first="A" last="Agashe">A. Agashe</name><name sortKey="Khandelwal, R" sort="Khandelwal, R" uniqKey="Khandelwal R" first="R" last="Khandelwal">R. Khandelwal</name><name sortKey="Majumdar, M" sort="Majumdar, M" uniqKey="Majumdar M" first="M" last="Majumdar">M. Majumdar</name><name sortKey="Raje, D" sort="Raje, D" uniqKey="Raje D" first="D" last="Raje">D. Raje</name><name sortKey="Rathi, A" sort="Rathi, A" uniqKey="Rathi A" first="A" last="Rathi">A. Rathi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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