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Creation of Various Skin Sensations Using Pulsed Focused Ultrasound: Evidence for Functional Neuromodulation

Identifieur interne : 001201 ( PascalFrancis/Curation ); précédent : 001200; suivant : 001202

Creation of Various Skin Sensations Using Pulsed Focused Ultrasound: Evidence for Functional Neuromodulation

Auteurs : WONHYE LEE [Corée du Sud] ; HYUNGMIN KIM [Corée du Sud] ; SUNGON LEE [Corée du Sud] ; Seung-Schik Yoo [Corée du Sud] ; YONG AN CHUNG [Corée du Sud]

Source :

RBID : Pascal:14-0173623

Descripteurs français

English descriptors

Abstract

Ultrasound application to neural tissues modifies their activity, and it is increasingly considered as a new mode of functional neuromodulation in both central and peripheral nervous system. We investigate that ultrasound focused to skin surface can induce differential peripheral sensations by modulating the activity of sensory receptors. Pulsed focused ultrasound was applied to the last digit of human hands for 10 s using combinations of acoustic frequencies (350 and 650 kHz), tone-burst-durations (0.1 and 1.0 ms), pulse repetition frequencies (10 and 100 Hz) with 1% duty cycle, and acoustic intensities (3-100 mW/cm2), divided into two ambient temperatures (20 and 40°C). On insonification, volunteers reported cooling, warming, vibrotactile sensations, and mild nociception, while there was no actual increase to the skin temperature. Continuous insonification, in contrast to pulsed insonification, failed to elicit these sensations. Our results suggest that pulsed ultrasound temporarily modifies the activity of the sensory receptors on the skin, and casts future utility in dermatological applications as well as in the field of haptic device interfaces.
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A03   1    @0 Int. j. imaging syst. technol.
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A08 01  1  ENG  @1 Creation of Various Skin Sensations Using Pulsed Focused Ultrasound: Evidence for Functional Neuromodulation
A11 01  1    @1 WONHYE LEE
A11 02  1    @1 HYUNGMIN KIM
A11 03  1    @1 SUNGON LEE
A11 04  1    @1 YOO (Seung-Schik)
A11 05  1    @1 YONG AN CHUNG
A14 01      @1 School of Nano-Bioscience and Chemical Engineering, Ulsan National Institute of Science and Technology @2 Ulju-gun, Ulsan 689-798 @3 KOR @Z 1 aut.
A14 02      @1 Incheon St. Mary's Hospital, The Catholic University of Korea @2 Bupyeong-gu, Incheon 403-720 @3 KOR @Z 1 aut. @Z 2 aut. @Z 4 aut. @Z 5 aut.
A14 03      @1 Center for Bionics, Korea Institute of Science and Technology @2 Seongbuk-gu, Seoul 136-791 @3 KOR @Z 2 aut.
A14 04      @1 Interaction and Robotics Research Center, Korea Institute of Science and Technology @2 Seongbuk-gu, Seoul 136-791 @3 KOR @Z 3 aut.
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A21       @1 2014
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C01 01    ENG  @0 Ultrasound application to neural tissues modifies their activity, and it is increasingly considered as a new mode of functional neuromodulation in both central and peripheral nervous system. We investigate that ultrasound focused to skin surface can induce differential peripheral sensations by modulating the activity of sensory receptors. Pulsed focused ultrasound was applied to the last digit of human hands for 10 s using combinations of acoustic frequencies (350 and 650 kHz), tone-burst-durations (0.1 and 1.0 ms), pulse repetition frequencies (10 and 100 Hz) with 1% duty cycle, and acoustic intensities (3-100 mW/cm2), divided into two ambient temperatures (20 and 40°C). On insonification, volunteers reported cooling, warming, vibrotactile sensations, and mild nociception, while there was no actual increase to the skin temperature. Continuous insonification, in contrast to pulsed insonification, failed to elicit these sensations. Our results suggest that pulsed ultrasound temporarily modifies the activity of the sensory receptors on the skin, and casts future utility in dermatological applications as well as in the field of haptic device interfaces.
C02 01  X    @0 002A25F
C03 01  X  FRE  @0 Ultrason @5 06
C03 01  X  ENG  @0 Ultrasound @5 06
C03 01  X  SPA  @0 Ultrasonido @5 06
C03 02  X  FRE  @0 Température ambiante @5 07
C03 02  X  ENG  @0 Room temperature @5 07
C03 02  X  SPA  @0 Temperatura ambiente @5 07
C03 03  X  FRE  @0 Sensibilité tactile @5 08
C03 03  X  ENG  @0 Tactile sensitivity @5 08
C03 03  X  SPA  @0 Sensibilidad tactil @5 08
C03 04  X  FRE  @0 Interface utilisateur @5 09
C03 04  X  ENG  @0 User interface @5 09
C03 04  X  SPA  @0 Interfase usuario @5 09
C03 05  X  FRE  @0 Neuromodulation @5 18
C03 05  X  ENG  @0 Neuromodulation @5 18
C03 05  X  SPA  @0 Neuromodulación @5 18
C03 06  X  FRE  @0 Neurophysiologie @5 19
C03 06  X  ENG  @0 Neurophysiology @5 19
C03 06  X  SPA  @0 Neurofisiología @5 19
C03 07  X  FRE  @0 Système nerveux central @5 20
C03 07  X  ENG  @0 Central nervous system @5 20
C03 07  X  SPA  @0 Sistema nervioso central @5 20
C03 08  X  FRE  @0 Tissu @5 21
C03 08  X  ENG  @0 Tissue @5 21
C03 08  X  SPA  @0 Tejido @5 21
C03 09  X  FRE  @0 Système nerveux périphérique @5 22
C03 09  X  ENG  @0 Peripheral nervous system @5 22
C03 09  X  SPA  @0 Sistema nervioso periférico @5 22
C03 10  X  FRE  @0 Peau @5 23
C03 10  X  ENG  @0 Skin @5 23
C03 10  X  SPA  @0 Piel @5 23
C03 11  X  FRE  @0 Sensation @5 24
C03 11  X  ENG  @0 Sensation @5 24
C03 11  X  SPA  @0 Sensación @5 24
C03 12  X  FRE  @0 Récepteur sensoriel @5 25
C03 12  X  ENG  @0 Sensory receptor @5 25
C03 12  X  SPA  @0 Receptor sensorial @5 25
C03 13  X  FRE  @0 Main @5 26
C03 13  X  ENG  @0 Hand @5 26
C03 13  X  SPA  @0 Mano @5 26
C03 14  X  FRE  @0 Acoustique @5 27
C03 14  X  ENG  @0 Acoustics @5 27
C03 14  X  SPA  @0 Acústica @5 27
C03 15  X  FRE  @0 Répétition @5 28
C03 15  X  ENG  @0 Repetition @5 28
C03 15  X  SPA  @0 Repetición @5 28
C03 16  X  FRE  @0 Intensité acoustique @5 29
C03 16  X  ENG  @0 Acoustic intensity @5 29
C03 16  X  SPA  @0 Intensidad acústica @5 29
C03 17  X  FRE  @0 Durée @5 41
C03 17  X  ENG  @0 Duration @5 41
C03 17  X  SPA  @0 Duración @5 41
C03 18  X  FRE  @0 . @4 INC @5 82
N21       @1 216
N44 01      @1 OTO
N82       @1 OTO

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Pascal:14-0173623

Le document en format XML

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<div type="abstract" xml:lang="en">Ultrasound application to neural tissues modifies their activity, and it is increasingly considered as a new mode of functional neuromodulation in both central and peripheral nervous system. We investigate that ultrasound focused to skin surface can induce differential peripheral sensations by modulating the activity of sensory receptors. Pulsed focused ultrasound was applied to the last digit of human hands for 10 s using combinations of acoustic frequencies (350 and 650 kHz), tone-burst-durations (0.1 and 1.0 ms), pulse repetition frequencies (10 and 100 Hz) with 1% duty cycle, and acoustic intensities (3-100 mW/cm
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<s5>07</s5>
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<fC03 i1="02" i2="X" l="SPA">
<s0>Temperatura ambiente</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Sensibilité tactile</s0>
<s5>08</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Tactile sensitivity</s0>
<s5>08</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Sensibilidad tactil</s0>
<s5>08</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Interface utilisateur</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>User interface</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Interfase usuario</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Neuromodulation</s0>
<s5>18</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Neuromodulation</s0>
<s5>18</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Neuromodulación</s0>
<s5>18</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Neurophysiologie</s0>
<s5>19</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Neurophysiology</s0>
<s5>19</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Neurofisiología</s0>
<s5>19</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Système nerveux central</s0>
<s5>20</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Central nervous system</s0>
<s5>20</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Sistema nervioso central</s0>
<s5>20</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE">
<s0>Tissu</s0>
<s5>21</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG">
<s0>Tissue</s0>
<s5>21</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA">
<s0>Tejido</s0>
<s5>21</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE">
<s0>Système nerveux périphérique</s0>
<s5>22</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG">
<s0>Peripheral nervous system</s0>
<s5>22</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA">
<s0>Sistema nervioso periférico</s0>
<s5>22</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE">
<s0>Peau</s0>
<s5>23</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG">
<s0>Skin</s0>
<s5>23</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA">
<s0>Piel</s0>
<s5>23</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE">
<s0>Sensation</s0>
<s5>24</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG">
<s0>Sensation</s0>
<s5>24</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA">
<s0>Sensación</s0>
<s5>24</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE">
<s0>Récepteur sensoriel</s0>
<s5>25</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG">
<s0>Sensory receptor</s0>
<s5>25</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA">
<s0>Receptor sensorial</s0>
<s5>25</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE">
<s0>Main</s0>
<s5>26</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG">
<s0>Hand</s0>
<s5>26</s5>
</fC03>
<fC03 i1="13" i2="X" l="SPA">
<s0>Mano</s0>
<s5>26</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE">
<s0>Acoustique</s0>
<s5>27</s5>
</fC03>
<fC03 i1="14" i2="X" l="ENG">
<s0>Acoustics</s0>
<s5>27</s5>
</fC03>
<fC03 i1="14" i2="X" l="SPA">
<s0>Acústica</s0>
<s5>27</s5>
</fC03>
<fC03 i1="15" i2="X" l="FRE">
<s0>Répétition</s0>
<s5>28</s5>
</fC03>
<fC03 i1="15" i2="X" l="ENG">
<s0>Repetition</s0>
<s5>28</s5>
</fC03>
<fC03 i1="15" i2="X" l="SPA">
<s0>Repetición</s0>
<s5>28</s5>
</fC03>
<fC03 i1="16" i2="X" l="FRE">
<s0>Intensité acoustique</s0>
<s5>29</s5>
</fC03>
<fC03 i1="16" i2="X" l="ENG">
<s0>Acoustic intensity</s0>
<s5>29</s5>
</fC03>
<fC03 i1="16" i2="X" l="SPA">
<s0>Intensidad acústica</s0>
<s5>29</s5>
</fC03>
<fC03 i1="17" i2="X" l="FRE">
<s0>Durée</s0>
<s5>41</s5>
</fC03>
<fC03 i1="17" i2="X" l="ENG">
<s0>Duration</s0>
<s5>41</s5>
</fC03>
<fC03 i1="17" i2="X" l="SPA">
<s0>Duración</s0>
<s5>41</s5>
</fC03>
<fC03 i1="18" i2="X" l="FRE">
<s0>.</s0>
<s4>INC</s4>
<s5>82</s5>
</fC03>
<fN21>
<s1>216</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

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   |wiki=    Ticri/CIDE
   |area=    HapticV1
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   |texte=   Creation of Various Skin Sensations Using Pulsed Focused Ultrasound: Evidence for Functional Neuromodulation
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