Anterior capsule opacification : A histopathological study comparing different IOL styles
Identifieur interne : 001487 ( PascalFrancis/Corpus ); précédent : 001486; suivant : 001488Anterior capsule opacification : A histopathological study comparing different IOL styles
Auteurs : L. Werner ; S. K. Pandey ; M. Escobar-Gomez ; N. Visessook ; QUN PENG ; D. J. AppleSource :
- Ophthalmology : (Rochester, MN) [ 0161-6420 ] ; 2000.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Objective: To compare the degree of anterior capsule opacification (ACO) in human eyes obtained post-mortem containing various rigid and foldable posterior chamber intraocular lens (PC-IOL) designs. Design: Comparative autopsy tissue study with clinicopathologic correlations. Materials: Four hundred sixty human globes containing the following PC-IOL styles were analyzed: (1) one-piece polymethylmethacrylate (PMMA) optic-PMMA haptic (n = 50)r (2) one-piece silicone-plate IOL, large hole (n = 40), (3) one-piece silicone-plate IOL, small hole (n = 67), (4) three-piece PMMA optic-PMMA/Prolene haptic (n = 51), (5) three-piece acrylic optic-PMMA haptic (n = 96), (6) three-piece silicone optic-PMMA haptic (n = 24), (7) three-piece silicone optic-polyimide haptic (n = 40), and (8) three-piece silicone optic-prolene haptic (n = 92). Testing: The globes were sectioned in the equatorial plane for gross examination and then processed through paraffin; sectioned, and stained with hematoxylin-eosin, periodic acid-Schiff, and Masson's trichrome stains; and examined by light microscopy. Main Outcome Measures: Anterior capsule opacification was scored in each eye by grading the histologic sections from 0 to III, according to the amount (thickness) of proliferative tissue and cells measured in sagittal sections on the inner surface of the anterior capsule at the capsulorhexis margin. Results: The difference among the eight groups was significant (P < 0.0001). Mean ACO scores were highest with the large and small hole one-piece silicone-plate lenses (1.77 ± 0.86 and 1.28 ± 0.77, respectively). The lowest mean score was observed in the group of three-piece acrylic optic-PMMA haptics lenses (0.51 ± 0.52). Conclusions: Our results confirm previous clinical observations that the rate of ACO is relatively high with plate-haptic silicone lOLs. The lowest rate was noted with the three-piece acrylic optic-PMMA haptic IOL. The IOL design and IOL material are significant factors in the development of ACO.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
| pA |
|
|---|
Format Inist (serveur)
| NO : | PASCAL 00-0172600 INIST |
|---|---|
| ET : | Anterior capsule opacification : A histopathological study comparing different IOL styles |
| AU : | WERNER (L.); PANDEY (S. K.); ESCOBAR-GOMEZ (M.); VISESSOOK (N.); QUN PENG; APPLE (D. J.) |
| AF : | Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina/Charleston, South Carolina/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut.) |
| DT : | Publication en série; Niveau analytique |
| SO : | Ophthalmology : (Rochester, MN); ISSN 0161-6420; Coden OPHTDG; Etats-Unis; Da. 2000; Vol. 107; No. 3; Pp. 463-471; Bibl. 40 ref. |
| LA : | Anglais |
| EA : | Objective: To compare the degree of anterior capsule opacification (ACO) in human eyes obtained post-mortem containing various rigid and foldable posterior chamber intraocular lens (PC-IOL) designs. Design: Comparative autopsy tissue study with clinicopathologic correlations. Materials: Four hundred sixty human globes containing the following PC-IOL styles were analyzed: (1) one-piece polymethylmethacrylate (PMMA) optic-PMMA haptic (n = 50)r (2) one-piece silicone-plate IOL, large hole (n = 40), (3) one-piece silicone-plate IOL, small hole (n = 67), (4) three-piece PMMA optic-PMMA/Prolene haptic (n = 51), (5) three-piece acrylic optic-PMMA haptic (n = 96), (6) three-piece silicone optic-PMMA haptic (n = 24), (7) three-piece silicone optic-polyimide haptic (n = 40), and (8) three-piece silicone optic-prolene haptic (n = 92). Testing: The globes were sectioned in the equatorial plane for gross examination and then processed through paraffin; sectioned, and stained with hematoxylin-eosin, periodic acid-Schiff, and Masson's trichrome stains; and examined by light microscopy. Main Outcome Measures: Anterior capsule opacification was scored in each eye by grading the histologic sections from 0 to III, according to the amount (thickness) of proliferative tissue and cells measured in sagittal sections on the inner surface of the anterior capsule at the capsulorhexis margin. Results: The difference among the eight groups was significant (P < 0.0001). Mean ACO scores were highest with the large and small hole one-piece silicone-plate lenses (1.77 ± 0.86 and 1.28 ± 0.77, respectively). The lowest mean score was observed in the group of three-piece acrylic optic-PMMA haptics lenses (0.51 ± 0.52). Conclusions: Our results confirm previous clinical observations that the rate of ACO is relatively high with plate-haptic silicone lOLs. The lowest rate was noted with the three-piece acrylic optic-PMMA haptic IOL. The IOL design and IOL material are significant factors in the development of ACO. |
| CC : | 002B25B |
| FD : | Lentille intraoculaire; Oeil; Biomatériau; Siloxane polymère; Méthacrylate de méthyle polymère; Etude comparative; Opacification; Capsule; Antérieur; Histopathologie; Autopsie; Homme |
| FG : | Chirurgie; Oeil pathologie |
| ED : | Intraocular lens; Eye; Biomaterial; Siloxane polymer; Methyl methacrylate polymer; Comparative study; Opacification; Capsule; Anterior; Histopathology; Autopsy; Human |
| EG : | Surgery; Eye disease |
| SD : | Lente intraocular; Ojo; Biomaterial; Siloxano polímero; Metacrilato de metilo polímero; Estudio comparativo; Opacificación; Cápsula; Anterior; Histopatología; Autopsia; Hombre |
| LO : | INIST-18914.354000081967510130 |
| ID : | 00-0172600 |
Links to Exploration step
Pascal:00-0172600Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Anterior capsule opacification : A histopathological study comparing different IOL styles</title><author><name sortKey="Werner, L" sort="Werner, L" uniqKey="Werner L" first="L." last="Werner">L. Werner</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Pandey, S K" sort="Pandey, S K" uniqKey="Pandey S" first="S. K." last="Pandey">S. K. Pandey</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Escobar Gomez, M" sort="Escobar Gomez, M" uniqKey="Escobar Gomez M" first="M." last="Escobar-Gomez">M. Escobar-Gomez</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Visessook, N" sort="Visessook, N" uniqKey="Visessook N" first="N." last="Visessook">N. Visessook</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Qun Peng" sort="Qun Peng" uniqKey="Qun Peng" last="Qun Peng">QUN PENG</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D. J." last="Apple">D. J. Apple</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">00-0172600</idno><date when="2000">2000</date><idno type="stanalyst">PASCAL 00-0172600 INIST</idno><idno type="RBID">Pascal:00-0172600</idno><idno type="wicri:Area/PascalFrancis/Corpus">001487</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Anterior capsule opacification : A histopathological study comparing different IOL styles</title><author><name sortKey="Werner, L" sort="Werner, L" uniqKey="Werner L" first="L." last="Werner">L. Werner</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Pandey, S K" sort="Pandey, S K" uniqKey="Pandey S" first="S. K." last="Pandey">S. K. Pandey</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Escobar Gomez, M" sort="Escobar Gomez, M" uniqKey="Escobar Gomez M" first="M." last="Escobar-Gomez">M. Escobar-Gomez</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Visessook, N" sort="Visessook, N" uniqKey="Visessook N" first="N." last="Visessook">N. Visessook</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Qun Peng" sort="Qun Peng" uniqKey="Qun Peng" last="Qun Peng">QUN PENG</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author><author><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D. J." last="Apple">D. J. Apple</name><affiliation><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14></affiliation></author></analytic><series><title level="j" type="main">Ophthalmology : (Rochester, MN)</title><title level="j" type="abbreviated">Ophthalmology : (Rochester MN)</title><idno type="ISSN">0161-6420</idno><imprint><date when="2000">2000</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Ophthalmology : (Rochester, MN)</title><title level="j" type="abbreviated">Ophthalmology : (Rochester MN)</title><idno type="ISSN">0161-6420</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anterior</term><term>Autopsy</term><term>Biomaterial</term><term>Capsule</term><term>Comparative study</term><term>Eye</term><term>Histopathology</term><term>Human</term><term>Intraocular lens</term><term>Methyl methacrylate polymer</term><term>Opacification</term><term>Siloxane polymer</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Lentille intraoculaire</term><term>Oeil</term><term>Biomatériau</term><term>Siloxane polymère</term><term>Méthacrylate de méthyle polymère</term><term>Etude comparative</term><term>Opacification</term><term>Capsule</term><term>Antérieur</term><term>Histopathologie</term><term>Autopsie</term><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: To compare the degree of anterior capsule opacification (ACO) in human eyes obtained post-mortem containing various rigid and foldable posterior chamber intraocular lens (PC-IOL) designs. Design: Comparative autopsy tissue study with clinicopathologic correlations. Materials: Four hundred sixty human globes containing the following PC-IOL styles were analyzed: (1) one-piece polymethylmethacrylate (PMMA) optic-PMMA haptic (n = 50)<sub>r</sub> (2) one-piece silicone-plate IOL, large hole (n = 40), (3) one-piece silicone-plate IOL, small hole (n = 67), (4) three-piece PMMA optic-PMMA/Prolene haptic (n = 51), (5) three-piece acrylic optic-PMMA haptic (n = 96), (6) three-piece silicone optic-PMMA haptic (n = 24), (7) three-piece silicone optic-polyimide haptic (n = 40), and (8) three-piece silicone optic-prolene haptic (n = 92). Testing: The globes were sectioned in the equatorial plane for gross examination and then processed through paraffin; sectioned, and stained with hematoxylin-eosin, periodic acid-Schiff, and Masson's trichrome stains; and examined by light microscopy. Main Outcome Measures: Anterior capsule opacification was scored in each eye by grading the histologic sections from 0 to III, according to the amount (thickness) of proliferative tissue and cells measured in sagittal sections on the inner surface of the anterior capsule at the capsulorhexis margin. Results: The difference among the eight groups was significant (P < 0.0001). Mean ACO scores were highest with the large and small hole one-piece silicone-plate lenses (1.77 ± 0.86 and 1.28 ± 0.77, respectively). The lowest mean score was observed in the group of three-piece acrylic optic-PMMA haptics lenses (0.51 ± 0.52). Conclusions: Our results confirm previous clinical observations that the rate of ACO is relatively high with plate-haptic silicone lOLs. The lowest rate was noted with the three-piece acrylic optic-PMMA haptic IOL. The IOL design and IOL material are significant factors in the development of ACO.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0161-6420</s0></fA01><fA02 i1="01"><s0>OPHTDG</s0></fA02><fA03 i2="1"><s0>Ophthalmology : (Rochester MN)</s0></fA03><fA05><s2>107</s2></fA05><fA06><s2>3</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Anterior capsule opacification : A histopathological study comparing different IOL styles</s1></fA08><fA11 i1="01" i2="1"><s1>WERNER (L.)</s1></fA11><fA11 i1="02" i2="1"><s1>PANDEY (S. K.)</s1></fA11><fA11 i1="03" i2="1"><s1>ESCOBAR-GOMEZ (M.)</s1></fA11><fA11 i1="04" i2="1"><s1>VISESSOOK (N.)</s1></fA11><fA11 i1="05" i2="1"><s1>QUN PENG</s1></fA11><fA11 i1="06" i2="1"><s1>APPLE (D. J.)</s1></fA11><fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></fA14><fA20><s1>463-471</s1></fA20><fA21><s1>2000</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>18914</s2><s5>354000081967510130</s5></fA43><fA44><s0>0000</s0><s1>© 2000 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>40 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>00-0172600</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Ophthalmology : (Rochester, MN)</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>Objective: To compare the degree of anterior capsule opacification (ACO) in human eyes obtained post-mortem containing various rigid and foldable posterior chamber intraocular lens (PC-IOL) designs. Design: Comparative autopsy tissue study with clinicopathologic correlations. Materials: Four hundred sixty human globes containing the following PC-IOL styles were analyzed: (1) one-piece polymethylmethacrylate (PMMA) optic-PMMA haptic (n = 50)<sub>r</sub> (2) one-piece silicone-plate IOL, large hole (n = 40), (3) one-piece silicone-plate IOL, small hole (n = 67), (4) three-piece PMMA optic-PMMA/Prolene haptic (n = 51), (5) three-piece acrylic optic-PMMA haptic (n = 96), (6) three-piece silicone optic-PMMA haptic (n = 24), (7) three-piece silicone optic-polyimide haptic (n = 40), and (8) three-piece silicone optic-prolene haptic (n = 92). Testing: The globes were sectioned in the equatorial plane for gross examination and then processed through paraffin; sectioned, and stained with hematoxylin-eosin, periodic acid-Schiff, and Masson's trichrome stains; and examined by light microscopy. Main Outcome Measures: Anterior capsule opacification was scored in each eye by grading the histologic sections from 0 to III, according to the amount (thickness) of proliferative tissue and cells measured in sagittal sections on the inner surface of the anterior capsule at the capsulorhexis margin. Results: The difference among the eight groups was significant (P < 0.0001). Mean ACO scores were highest with the large and small hole one-piece silicone-plate lenses (1.77 ± 0.86 and 1.28 ± 0.77, respectively). The lowest mean score was observed in the group of three-piece acrylic optic-PMMA haptics lenses (0.51 ± 0.52). Conclusions: Our results confirm previous clinical observations that the rate of ACO is relatively high with plate-haptic silicone lOLs. The lowest rate was noted with the three-piece acrylic optic-PMMA haptic IOL. The IOL design and IOL material are significant factors in the development of ACO.</s0></fC01><fC02 i1="01" i2="X"><s0>002B25B</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Lentille intraoculaire</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Intraocular lens</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Lente intraocular</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Oeil</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Eye</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Ojo</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Biomatériau</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Biomaterial</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Biomaterial</s0><s5>03</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Siloxane polymère</s0><s2>NK</s2><s5>04</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Siloxane polymer</s0><s2>NK</s2><s5>04</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Siloxano polímero</s0><s2>NK</s2><s5>04</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Méthacrylate de méthyle polymère</s0><s2>NK</s2><s5>05</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Methyl methacrylate polymer</s0><s2>NK</s2><s5>05</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Metacrilato de metilo polímero</s0><s2>NK</s2><s5>05</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Etude comparative</s0><s5>06</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Comparative study</s0><s5>06</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Estudio comparativo</s0><s5>06</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Opacification</s0><s5>07</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Opacification</s0><s5>07</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Opacificación</s0><s5>07</s5></fC03><fC03 i1="08" i2="X" l="FRE"><s0>Capsule</s0><s5>08</s5></fC03><fC03 i1="08" i2="X" l="ENG"><s0>Capsule</s0><s5>08</s5></fC03><fC03 i1="08" i2="X" l="SPA"><s0>Cápsula</s0><s5>08</s5></fC03><fC03 i1="09" i2="X" l="FRE"><s0>Antérieur</s0><s5>09</s5></fC03><fC03 i1="09" i2="X" l="ENG"><s0>Anterior</s0><s5>09</s5></fC03><fC03 i1="09" i2="X" l="SPA"><s0>Anterior</s0><s5>09</s5></fC03><fC03 i1="10" i2="X" l="FRE"><s0>Histopathologie</s0><s5>10</s5></fC03><fC03 i1="10" i2="X" l="ENG"><s0>Histopathology</s0><s5>10</s5></fC03><fC03 i1="10" i2="X" l="SPA"><s0>Histopatología</s0><s5>10</s5></fC03><fC03 i1="11" i2="X" l="FRE"><s0>Autopsie</s0><s5>11</s5></fC03><fC03 i1="11" i2="X" l="ENG"><s0>Autopsy</s0><s5>11</s5></fC03><fC03 i1="11" i2="X" l="SPA"><s0>Autopsia</s0><s5>11</s5></fC03><fC03 i1="12" i2="X" l="FRE"><s0>Homme</s0><s5>13</s5></fC03><fC03 i1="12" i2="X" l="ENG"><s0>Human</s0><s5>13</s5></fC03><fC03 i1="12" i2="X" l="SPA"><s0>Hombre</s0><s5>13</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Chirurgie</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Surgery</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Cirugía</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Oeil pathologie</s0><s5>53</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Eye disease</s0><s5>53</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Ojo patología</s0><s5>53</s5></fC07><fN21><s1>129</s1></fN21></pA></standard><server><NO>PASCAL 00-0172600 INIST</NO><ET>Anterior capsule opacification : A histopathological study comparing different IOL styles</ET><AU>WERNER (L.); PANDEY (S. K.); ESCOBAR-GOMEZ (M.); VISESSOOK (N.); QUN PENG; APPLE (D. J.)</AU><AF>Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina/Charleston, South Carolina/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut., 6 aut.)</AF><DT>Publication en série; Niveau analytique</DT><SO>Ophthalmology : (Rochester, MN); ISSN 0161-6420; Coden OPHTDG; Etats-Unis; Da. 2000; Vol. 107; No. 3; Pp. 463-471; Bibl. 40 ref.</SO><LA>Anglais</LA><EA>Objective: To compare the degree of anterior capsule opacification (ACO) in human eyes obtained post-mortem containing various rigid and foldable posterior chamber intraocular lens (PC-IOL) designs. Design: Comparative autopsy tissue study with clinicopathologic correlations. Materials: Four hundred sixty human globes containing the following PC-IOL styles were analyzed: (1) one-piece polymethylmethacrylate (PMMA) optic-PMMA haptic (n = 50)<sub>r</sub> (2) one-piece silicone-plate IOL, large hole (n = 40), (3) one-piece silicone-plate IOL, small hole (n = 67), (4) three-piece PMMA optic-PMMA/Prolene haptic (n = 51), (5) three-piece acrylic optic-PMMA haptic (n = 96), (6) three-piece silicone optic-PMMA haptic (n = 24), (7) three-piece silicone optic-polyimide haptic (n = 40), and (8) three-piece silicone optic-prolene haptic (n = 92). Testing: The globes were sectioned in the equatorial plane for gross examination and then processed through paraffin; sectioned, and stained with hematoxylin-eosin, periodic acid-Schiff, and Masson's trichrome stains; and examined by light microscopy. Main Outcome Measures: Anterior capsule opacification was scored in each eye by grading the histologic sections from 0 to III, according to the amount (thickness) of proliferative tissue and cells measured in sagittal sections on the inner surface of the anterior capsule at the capsulorhexis margin. Results: The difference among the eight groups was significant (P < 0.0001). Mean ACO scores were highest with the large and small hole one-piece silicone-plate lenses (1.77 ± 0.86 and 1.28 ± 0.77, respectively). The lowest mean score was observed in the group of three-piece acrylic optic-PMMA haptics lenses (0.51 ± 0.52). Conclusions: Our results confirm previous clinical observations that the rate of ACO is relatively high with plate-haptic silicone lOLs. The lowest rate was noted with the three-piece acrylic optic-PMMA haptic IOL. The IOL design and IOL material are significant factors in the development of ACO.</EA><CC>002B25B</CC><FD>Lentille intraoculaire; Oeil; Biomatériau; Siloxane polymère; Méthacrylate de méthyle polymère; Etude comparative; Opacification; Capsule; Antérieur; Histopathologie; Autopsie; Homme</FD><FG>Chirurgie; Oeil pathologie</FG><ED>Intraocular lens; Eye; Biomaterial; Siloxane polymer; Methyl methacrylate polymer; Comparative study; Opacification; Capsule; Anterior; Histopathology; Autopsy; Human</ED><EG>Surgery; Eye disease</EG><SD>Lente intraocular; Ojo; Biomaterial; Siloxano polímero; Metacrilato de metilo polímero; Estudio comparativo; Opacificación; Cápsula; Anterior; Histopatología; Autopsia; Hombre</SD><LO>INIST-18914.354000081967510130</LO><ID>00-0172600</ID></server></inist></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001487 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 001487 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= PascalFrancis
|étape= Corpus
|type= RBID
|clé= Pascal:00-0172600
|texte= Anterior capsule opacification : A histopathological study comparing different IOL styles
}}
| This area was generated with Dilib version V0.6.23. |  |