Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification : Five-year results of a randomized study
Identifieur interne : 000B09 ( PascalFrancis/Checkpoint ); précédent : 000B08; suivant : 000B10Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification : Five-year results of a randomized study
Auteurs : Stefan Sacu [Autriche] ; Rupert Menapace [Autriche] ; Oliver Findl [Autriche] ; Barbara Kiss [Autriche] ; Wolf Buehl [Autriche] ; Michael Georgopoulos [Autriche]Source :
- American journal of ophthalmology [ 0002-9394 ] ; 2005.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Optique.
English descriptors
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Abstract
● PURPOSE: To compare the intensity of capsule opacification with the sharp and the round optic edge variant of an open-loop hydrophobic silicone intraocular lens (IOL). ● DESIGN: Randomized, controlled, double-blind clinical trial with intraindividual comparison. ● METHODS: Fifty-one patients with bilateral age-related cataract were included (102 eyes). Each patient had had cataract surgery in both eyes and received a Microsil IOL with a sharp optic edge design (model S) in one eye and a Microsil IOL with a round optic edge design (model R) in the fellow eye. Both IOLs had an identical haptic design (nonangulated polymethylmethacrylate) and silicone optic material. The patients were examined at the slit lamp, best-corrected visual acuity was assessed, and standardized high-resolution digital retroillumination images of the posterior capsule were taken 5 years after surgery. The intensity of regeneratory posterior capsule opacification (rPCO), fibrotic PCO (fPCO), and anterior capsule opacification (ACO) was assessed subjectively at the slit lamp, and of rPCO, objectively using automated image analysis software (AQUA). The need for an Nd:YAG laser capsulotomy (Nd:YAG-LCT) was noted. ● RESULTS: The mean AQUA PCO score was 1.2 for the model S and 2.4 for the model R lens (P =.001). The model S lens also led to less peripheral fPCO (P = .003). Concerning ACO, there was no significant difference between both IOL groups (P =.72). Whereas no capsulotomy was required with the model S, four cases (16%) had been performed in the model R group. ● CONCLUSION: Five years postoperatively, the sharp-edged silicone IOL showed less rPCO and fPCO than the round-edged IOL. However, regarding ACO, there was no significant difference between both IOL styles.
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University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Findl, Oliver" sort="Findl, Oliver" uniqKey="Findl O" first="Oliver" last="Findl">Oliver Findl</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Kiss, Barbara" sort="Kiss, Barbara" uniqKey="Kiss B" first="Barbara" last="Kiss">Barbara Kiss</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Georgopoulos, Michael" sort="Georgopoulos, Michael" uniqKey="Georgopoulos M" first="Michael" last="Georgopoulos">Michael Georgopoulos</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">05-0492926</idno><date when="2005">2005</date><idno type="stanalyst">PASCAL 05-0492926 INIST</idno><idno type="RBID">Pascal:05-0492926</idno><idno type="wicri:Area/PascalFrancis/Corpus">000E44</idno><idno type="wicri:Area/PascalFrancis/Curation">000664</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000B09</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification : Five-year results of a randomized study</title><author><name sortKey="Sacu, Stefan" sort="Sacu, Stefan" uniqKey="Sacu S" first="Stefan" last="Sacu">Stefan Sacu</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Menapace, Rupert" sort="Menapace, Rupert" uniqKey="Menapace R" first="Rupert" last="Menapace">Rupert Menapace</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Findl, Oliver" sort="Findl, Oliver" uniqKey="Findl O" first="Oliver" last="Findl">Oliver Findl</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Kiss, Barbara" sort="Kiss, Barbara" uniqKey="Kiss B" first="Barbara" last="Kiss">Barbara Kiss</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Georgopoulos, Michael" sort="Georgopoulos, Michael" uniqKey="Georgopoulos M" first="Michael" last="Georgopoulos">Michael Georgopoulos</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author></analytic><series><title level="j" type="main">American journal of ophthalmology</title><title level="j" type="abbreviated">Am. j. ophthalmol.</title><idno type="ISSN">0002-9394</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">American journal of ophthalmology</title><title level="j" type="abbreviated">Am. j. ophthalmol.</title><idno type="ISSN">0002-9394</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Capsule</term><term>Edge</term><term>Intraocular lens</term><term>Long term</term><term>Opacification</term><term>Ophthalmology</term><term>Optics</term><term>Posterior</term><term>Randomization</term><term>Siloxane polymer</term><term>Treatment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Long terme</term><term>Postérieur</term><term>Optique</term><term>Bord</term><term>Siloxane polymère</term><term>Lentille intraoculaire</term><term>Capsule</term><term>Opacification</term><term>Randomisation</term><term>Ophtalmologie</term><term>Traitement</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Optique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">● PURPOSE: To compare the intensity of capsule opacification with the sharp and the round optic edge variant of an open-loop hydrophobic silicone intraocular lens (IOL). ● DESIGN: Randomized, controlled, double-blind clinical trial with intraindividual comparison. ● METHODS: Fifty-one patients with bilateral age-related cataract were included (102 eyes). Each patient had had cataract surgery in both eyes and received a Microsil IOL with a sharp optic edge design (model S) in one eye and a Microsil IOL with a round optic edge design (model R) in the fellow eye. Both IOLs had an identical haptic design (nonangulated polymethylmethacrylate) and silicone optic material. The patients were examined at the slit lamp, best-corrected visual acuity was assessed, and standardized high-resolution digital retroillumination images of the posterior capsule were taken 5 years after surgery. The intensity of regeneratory posterior capsule opacification (rPCO), fibrotic PCO (fPCO), and anterior capsule opacification (ACO) was assessed subjectively at the slit lamp, and of rPCO, objectively using automated image analysis software (AQUA). The need for an Nd:YAG laser capsulotomy (Nd:YAG-LCT) was noted. ● RESULTS: The mean AQUA PCO score was 1.2 for the model S and 2.4 for the model R lens (P =.001). The model S lens also led to less peripheral fPCO (P = .003). Concerning ACO, there was no significant difference between both IOL groups (P =.72). Whereas no capsulotomy was required with the model S, four cases (16%) had been performed in the model R group. ● CONCLUSION: Five years postoperatively, the sharp-edged silicone IOL showed less rPCO and fPCO than the round-edged IOL. However, regarding ACO, there was no significant difference between both IOL styles.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0002-9394</s0></fA01><fA02 i1="01"><s0>AJOPAA</s0></fA02><fA03 i2="1"><s0>Am. j. ophthalmol.</s0></fA03><fA05><s2>139</s2></fA05><fA06><s2>4</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification : Five-year results of a randomized study</s1></fA08><fA11 i1="01" i2="1"><s1>SACU (Stefan)</s1></fA11><fA11 i1="02" i2="1"><s1>MENAPACE (Rupert)</s1></fA11><fA11 i1="03" i2="1"><s1>FINDL (Oliver)</s1></fA11><fA11 i1="04" i2="1"><s1>KISS (Barbara)</s1></fA11><fA11 i1="05" i2="1"><s1>BUEHL (Wolf)</s1></fA11><fA11 i1="06" i2="1"><s1>GEORGOPOULOS (Michael)</s1></fA11><fA14 i1="01"><s1>Medical University of Vienna, Department of Ophthalmology</s1><s2>Vienna</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></fA14><fA20><s1>696-703</s1></fA20><fA21><s1>2005</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>2012</s2><s5>354000131935460160</s5></fA43><fA44><s0>0000</s0><s1>© 2005 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>29 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>05-0492926</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>American journal of ophthalmology</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>● PURPOSE: To compare the intensity of capsule opacification with the sharp and the round optic edge variant of an open-loop hydrophobic silicone intraocular lens (IOL). ● DESIGN: Randomized, controlled, double-blind clinical trial with intraindividual comparison. ● METHODS: Fifty-one patients with bilateral age-related cataract were included (102 eyes). Each patient had had cataract surgery in both eyes and received a Microsil IOL with a sharp optic edge design (model S) in one eye and a Microsil IOL with a round optic edge design (model R) in the fellow eye. Both IOLs had an identical haptic design (nonangulated polymethylmethacrylate) and silicone optic material. The patients were examined at the slit lamp, best-corrected visual acuity was assessed, and standardized high-resolution digital retroillumination images of the posterior capsule were taken 5 years after surgery. The intensity of regeneratory posterior capsule opacification (rPCO), fibrotic PCO (fPCO), and anterior capsule opacification (ACO) was assessed subjectively at the slit lamp, and of rPCO, objectively using automated image analysis software (AQUA). The need for an Nd:YAG laser capsulotomy (Nd:YAG-LCT) was noted. ● RESULTS: The mean AQUA PCO score was 1.2 for the model S and 2.4 for the model R lens (P =.001). The model S lens also led to less peripheral fPCO (P = .003). Concerning ACO, there was no significant difference between both IOL groups (P =.72). Whereas no capsulotomy was required with the model S, four cases (16%) had been performed in the model R group. ● CONCLUSION: Five years postoperatively, the sharp-edged silicone IOL showed less rPCO and fPCO than the round-edged IOL. However, regarding ACO, there was no significant difference between both IOL styles.</s0></fC01><fC02 i1="01" i2="X"><s0>002B09N</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Long terme</s0><s5>02</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Long term</s0><s5>02</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Largo plazo</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Postérieur</s0><s5>03</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Posterior</s0><s5>03</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Posterior</s0><s5>03</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Optique</s0><s5>05</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Optics</s0><s5>05</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Optica</s0><s5>05</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Bord</s0><s5>06</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Edge</s0><s5>06</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Borde</s0><s5>06</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Siloxane polymère</s0><s2>NK</s2><s5>08</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Siloxane polymer</s0><s2>NK</s2><s5>08</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Siloxano polímero</s0><s2>NK</s2><s5>08</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Lentille intraoculaire</s0><s5>09</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Intraocular lens</s0><s5>09</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Lente intraocular</s0><s5>09</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Capsule</s0><s5>11</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Capsule</s0><s5>11</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Cápsula</s0><s5>11</s5></fC03><fC03 i1="08" i2="X" l="FRE"><s0>Opacification</s0><s5>12</s5></fC03><fC03 i1="08" i2="X" l="ENG"><s0>Opacification</s0><s5>12</s5></fC03><fC03 i1="08" i2="X" l="SPA"><s0>Opacificación</s0><s5>12</s5></fC03><fC03 i1="09" i2="X" l="FRE"><s0>Randomisation</s0><s5>14</s5></fC03><fC03 i1="09" i2="X" l="ENG"><s0>Randomization</s0><s5>14</s5></fC03><fC03 i1="09" i2="X" l="SPA"><s0>Aleatorización</s0><s5>14</s5></fC03><fC03 i1="10" i2="X" l="FRE"><s0>Ophtalmologie</s0><s5>15</s5></fC03><fC03 i1="10" i2="X" l="ENG"><s0>Ophthalmology</s0><s5>15</s5></fC03><fC03 i1="10" i2="X" l="SPA"><s0>Oftalmología</s0><s5>15</s5></fC03><fC03 i1="11" i2="X" l="FRE"><s0>Traitement</s0><s5>25</s5></fC03><fC03 i1="11" i2="X" l="ENG"><s0>Treatment</s0><s5>25</s5></fC03><fC03 i1="11" i2="X" l="SPA"><s0>Tratamiento</s0><s5>25</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Chirurgie</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Surgery</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Cirugía</s0><s5>37</s5></fC07><fN21><s1>346</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist><affiliations><list><country><li>Autriche</li></country><region><li>Vienne (Autriche)</li></region><settlement><li>Vienne (Autriche)</li></settlement></list><tree><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Sacu, Stefan" sort="Sacu, Stefan" uniqKey="Sacu S" first="Stefan" last="Sacu">Stefan Sacu</name></region><name sortKey="Buehl, Wolf" sort="Buehl, Wolf" uniqKey="Buehl W" first="Wolf" last="Buehl">Wolf Buehl</name><name sortKey="Findl, Oliver" sort="Findl, Oliver" uniqKey="Findl O" first="Oliver" last="Findl">Oliver Findl</name><name sortKey="Georgopoulos, Michael" sort="Georgopoulos, Michael" uniqKey="Georgopoulos M" first="Michael" last="Georgopoulos">Michael Georgopoulos</name><name sortKey="Kiss, Barbara" sort="Kiss, Barbara" uniqKey="Kiss B" first="Barbara" last="Kiss">Barbara Kiss</name><name sortKey="Menapace, Rupert" sort="Menapace, Rupert" uniqKey="Menapace R" first="Rupert" last="Menapace">Rupert Menapace</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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