Selective inhibition of a multicomponent response can be achieved without cost
Identifieur interne : 003391 ( Ncbi/Merge ); précédent : 003390; suivant : 003392Selective inhibition of a multicomponent response can be achieved without cost
Auteurs : Jing Xu [États-Unis] ; Zachary Westrick [États-Unis] ; Richard B. Ivry [États-Unis]Source :
- Journal of Neurophysiology [ 0022-3077 ] ; 2014.
Abstract
Behavioral flexibility frequently requires the ability to modify an on-going action. In some situations, optimal performance requires modifying some components of an on-going action without interrupting other components of that action. This form of control has been studied with the selective stop-signal task, in which participants are instructed to abort only one movement of a multicomponent response. Previous studies have shown a transient disruption of the nonaborted component, suggesting limitations in our ability to use selective inhibition. This cost has been attributed to a structural limitation associated with the recruitment of a cortico-basal ganglia pathway that allows for the rapid inhibition of action but operates in a relatively generic manner. Using a model-based approach, we demonstrate that, with a modest amount of training and highly compatible stimulus-response mappings, people can perform a selective-stop task without any cost on the nonaborted component. Prior reports of behavioral costs in selective-stop tasks reflect, at least in part, a sampling bias in the method commonly used to estimate such costs. These results suggest that inhibition can be selectively controlled and present a challenge for models of inhibitory control that posit the operation of generic processes.
Url:
DOI: 10.1152/jn.00101.2014
PubMed: 25339712
PubMed Central: 4297793
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PMC:4297793Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Behavioral flexibility frequently requires the ability to modify an on-going action. In some situations, optimal performance requires modifying some components of an on-going action without interrupting other components of that action. This form of control has been studied with the selective stop-signal task, in which participants are instructed to abort only one movement of a multicomponent response. Previous studies have shown a transient disruption of the nonaborted component, suggesting limitations in our ability to use selective inhibition. This cost has been attributed to a structural limitation associated with the recruitment of a cortico-basal ganglia pathway that allows for the rapid inhibition of action but operates in a relatively generic manner. Using a model-based approach, we demonstrate that, with a modest amount of training and highly compatible stimulus-response mappings, people can perform a selective-stop task without any cost on the nonaborted component. Prior reports of behavioral costs in selective-stop tasks reflect, at least in part, a sampling bias in the method commonly used to estimate such costs. These results suggest that inhibition can be selectively controlled and present a challenge for models of inhibitory control that posit the operation of generic processes.</p>
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<article-categories><subj-group subj-group-type="heading"><subject>Control of Movement</subject>
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<title-group><article-title>Selective inhibition of a multicomponent response can be achieved without cost</article-title>
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Department of Neurology, Johns Hopkins University, Baltimore, Maryland;</aff>
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Department of Psychology, New York University, New York, New York; and</aff>
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Department of Psychology, University of California, Berkeley, California</aff>
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<author-notes><corresp id="cor1">Address for reprint requests and other correspondence: J. Xu, <addr-line>Dept. of Neurology, School of Medicine, Johns Hopkins Univ., Pathology 2-210, 600 N. Wolfe St., Baltimore, MD 21287</addr-line>
(e-mail: <email>jing.xu@jhmi.edu</email>
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<pmc-comment> PMC Release delay is 12 months and 0 days and was based on the . </pmc-comment>
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<permissions><copyright-statement>Copyright © 2015 the American Physiological Society</copyright-statement>
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<abstract><p>Behavioral flexibility frequently requires the ability to modify an on-going action. In some situations, optimal performance requires modifying some components of an on-going action without interrupting other components of that action. This form of control has been studied with the selective stop-signal task, in which participants are instructed to abort only one movement of a multicomponent response. Previous studies have shown a transient disruption of the nonaborted component, suggesting limitations in our ability to use selective inhibition. This cost has been attributed to a structural limitation associated with the recruitment of a cortico-basal ganglia pathway that allows for the rapid inhibition of action but operates in a relatively generic manner. Using a model-based approach, we demonstrate that, with a modest amount of training and highly compatible stimulus-response mappings, people can perform a selective-stop task without any cost on the nonaborted component. Prior reports of behavioral costs in selective-stop tasks reflect, at least in part, a sampling bias in the method commonly used to estimate such costs. These results suggest that inhibition can be selectively controlled and present a challenge for models of inhibitory control that posit the operation of generic processes.</p>
</abstract>
<kwd-group><kwd>inhibition</kwd>
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<kwd>horse-race model</kwd>
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