DIMETER: A Haptic Master Device for Tremor Diagnosis in Neurodegenerative Diseases
Identifieur interne : 002D74 ( Ncbi/Merge ); précédent : 002D73; suivant : 002D75DIMETER: A Haptic Master Device for Tremor Diagnosis in Neurodegenerative Diseases
Auteurs : Roberto González ; Antonio Barrientos ; Jaime Del Cerro ; Benito CocaSource :
- Sensors (Basel, Switzerland) [ 1424-8220 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Neurodegenerative Diseases, Tremor.
- instrumentation : Diagnostic Techniques, Neurological.
- Biomechanical Phenomena, Humans, Movement, Neural Networks (Computer), Pattern Recognition, Automated, Software, Touch.
Abstract
In this study, a device based on patient motion capture is developed for the reliable and non-invasive diagnosis of neurodegenerative diseases. The primary objective of this study is the classification of differential diagnosis between Parkinson's disease (PD) and essential tremor (ET). The DIMETER system has been used in the diagnoses of a significant number of patients at two medical centers in Spain. Research studies on classification have primarily focused on the use of well-known and reliable diagnosis criteria developed by qualified personnel. Here, we first present a literature review of the methods used to detect and evaluate tremor; then, we describe the DIMETER device in terms of the software and hardware used and the battery of tests developed to obtain the best diagnoses. All of the tests are classified and described in terms of the characteristics of the data obtained. A list of parameters obtained from the tests is provided, and the results obtained using multilayer perceptron (MLP) neural networks are presented and analyzed.
Url:
DOI: 10.3390/s140304536
PubMed: 24608001
PubMed Central: 4003956
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">DIMETER: A Haptic Master Device for Tremor Diagnosis in Neurodegenerative Diseases</title><author><name sortKey="Gonzalez, Roberto" sort="Gonzalez, Roberto" uniqKey="Gonzalez R" first="Roberto" last="González">Roberto González</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Barrientos, Antonio" sort="Barrientos, Antonio" uniqKey="Barrientos A" first="Antonio" last="Barrientos">Antonio Barrientos</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Del Cerro, Jaime" sort="Del Cerro, Jaime" uniqKey="Del Cerro J" first="Jaime" last="Del Cerro">Jaime Del Cerro</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Coca, Benito" sort="Coca, Benito" uniqKey="Coca B" first="Benito" last="Coca">Benito Coca</name><affiliation><nlm:aff id="af2-sensors-14-04536"> ETSIDI-UPM, C/Ronda de Valencia 3, E-28012 Madrid, Spain; E-Mail:<email>benitomaria.coca.hernandez@alumnos.upm.es</email></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24608001</idno><idno type="pmc">4003956</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003956</idno><idno type="RBID">PMC:4003956</idno><idno type="doi">10.3390/s140304536</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">002473</idno><idno type="wicri:Area/Pmc/Curation">002473</idno><idno type="wicri:Area/Pmc/Checkpoint">000D25</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">000726</idno><idno type="wicri:Area/PubMed/Curation">000726</idno><idno type="wicri:Area/PubMed/Checkpoint">000688</idno><idno type="wicri:Area/Ncbi/Merge">002D74</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">DIMETER: A Haptic Master Device for Tremor Diagnosis in Neurodegenerative Diseases</title><author><name sortKey="Gonzalez, Roberto" sort="Gonzalez, Roberto" uniqKey="Gonzalez R" first="Roberto" last="González">Roberto González</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Barrientos, Antonio" sort="Barrientos, Antonio" uniqKey="Barrientos A" first="Antonio" last="Barrientos">Antonio Barrientos</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Del Cerro, Jaime" sort="Del Cerro, Jaime" uniqKey="Del Cerro J" first="Jaime" last="Del Cerro">Jaime Del Cerro</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Coca, Benito" sort="Coca, Benito" uniqKey="Coca B" first="Benito" last="Coca">Benito Coca</name><affiliation><nlm:aff id="af2-sensors-14-04536"> ETSIDI-UPM, C/Ronda de Valencia 3, E-28012 Madrid, Spain; E-Mail:<email>benitomaria.coca.hernandez@alumnos.upm.es</email></nlm:aff></affiliation></author></analytic><series><title level="j">Sensors (Basel, Switzerland)</title><idno type="eISSN">1424-8220</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomechanical Phenomena</term><term>Diagnostic Techniques, Neurological (instrumentation)</term><term>Humans</term><term>Movement</term><term>Neural Networks (Computer)</term><term>Neurodegenerative Diseases (diagnosis)</term><term>Pattern Recognition, Automated</term><term>Software</term><term>Touch</term><term>Tremor (diagnosis)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Neurodegenerative Diseases</term><term>Tremor</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Diagnostic Techniques, Neurological</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biomechanical Phenomena</term><term>Humans</term><term>Movement</term><term>Neural Networks (Computer)</term><term>Pattern Recognition, Automated</term><term>Software</term><term>Touch</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In this study, a device based on patient motion capture is developed for the reliable and non-invasive diagnosis of neurodegenerative diseases. The primary objective of this study is the classification of differential diagnosis between Parkinson's disease (PD) and essential tremor (ET). The DIMETER system has been used in the diagnoses of a significant number of patients at two medical centers in Spain. Research studies on classification have primarily focused on the use of well-known and reliable diagnosis criteria developed by qualified personnel. Here, we first present a literature review of the methods used to detect and evaluate tremor; then, we describe the DIMETER device in terms of the software and hardware used and the battery of tests developed to obtain the best diagnoses. All of the tests are classified and described in terms of the characteristics of the data obtained. A list of parameters obtained from the tests is provided, and the results obtained using multilayer perceptron (MLP) neural networks are presented and analyzed.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Rijk, M C" uniqKey="Rijk M">M.C. Rijk</name></author><author><name sortKey="Launer, L J" uniqKey="Launer L">L.J. Launer</name></author><author><name sortKey="Berger, K" uniqKey="Berger K">K. Berger</name></author><author><name sortKey="Breteler, M M" uniqKey="Breteler M">M.M. Breteler</name></author><author><name sortKey="Dartigues, J F" uniqKey="Dartigues J">J.F. Dartigues</name></author><author><name sortKey="Baldereschi, M" uniqKey="Baldereschi M">M. Baldereschi</name></author><author><name sortKey="Fratiglioni, L" uniqKey="Fratiglioni L">L. Fratiglioni</name></author><author><name sortKey="Lobo, A" uniqKey="Lobo A">A. Lobo</name></author><author><name sortKey="Marinez Lage, J" uniqKey="Marinez Lage J">J. 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Tax</name></author></analytic></biblStruct></listBibl></div1></back></TEI><double pmid="24608001"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">DIMETER: A Haptic Master Device for Tremor Diagnosis in Neurodegenerative Diseases</title><author><name sortKey="Gonzalez, Roberto" sort="Gonzalez, Roberto" uniqKey="Gonzalez R" first="Roberto" last="González">Roberto González</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Barrientos, Antonio" sort="Barrientos, Antonio" uniqKey="Barrientos A" first="Antonio" last="Barrientos">Antonio Barrientos</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Del Cerro, Jaime" sort="Del Cerro, Jaime" uniqKey="Del Cerro J" first="Jaime" last="Del Cerro">Jaime Del Cerro</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Coca, Benito" sort="Coca, Benito" uniqKey="Coca B" first="Benito" last="Coca">Benito Coca</name><affiliation><nlm:aff id="af2-sensors-14-04536"> ETSIDI-UPM, C/Ronda de Valencia 3, E-28012 Madrid, Spain; E-Mail:<email>benitomaria.coca.hernandez@alumnos.upm.es</email></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24608001</idno><idno type="pmc">4003956</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003956</idno><idno type="RBID">PMC:4003956</idno><idno type="doi">10.3390/s140304536</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">002473</idno><idno type="wicri:Area/Pmc/Curation">002473</idno><idno type="wicri:Area/Pmc/Checkpoint">000D25</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">DIMETER: A Haptic Master Device for Tremor Diagnosis in Neurodegenerative Diseases</title><author><name sortKey="Gonzalez, Roberto" sort="Gonzalez, Roberto" uniqKey="Gonzalez R" first="Roberto" last="González">Roberto González</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Barrientos, Antonio" sort="Barrientos, Antonio" uniqKey="Barrientos A" first="Antonio" last="Barrientos">Antonio Barrientos</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Del Cerro, Jaime" sort="Del Cerro, Jaime" uniqKey="Del Cerro J" first="Jaime" last="Del Cerro">Jaime Del Cerro</name><affiliation><nlm:aff id="af1-sensors-14-04536"> Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain; E-Mails:<email>antonio.barrientos@upm.es</email> (A.B.);<email>j.cerro@upm.es</email> (J.C.)</nlm:aff></affiliation></author><author><name sortKey="Coca, Benito" sort="Coca, Benito" uniqKey="Coca B" first="Benito" last="Coca">Benito Coca</name><affiliation><nlm:aff id="af2-sensors-14-04536"> ETSIDI-UPM, C/Ronda de Valencia 3, E-28012 Madrid, Spain; E-Mail:<email>benitomaria.coca.hernandez@alumnos.upm.es</email></nlm:aff></affiliation></author></analytic><series><title level="j">Sensors (Basel, Switzerland)</title><idno type="eISSN">1424-8220</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In this study, a device based on patient motion capture is developed for the reliable and non-invasive diagnosis of neurodegenerative diseases. The primary objective of this study is the classification of differential diagnosis between Parkinson's disease (PD) and essential tremor (ET). The DIMETER system has been used in the diagnoses of a significant number of patients at two medical centers in Spain. Research studies on classification have primarily focused on the use of well-known and reliable diagnosis criteria developed by qualified personnel. Here, we first present a literature review of the methods used to detect and evaluate tremor; then, we describe the DIMETER device in terms of the software and hardware used and the battery of tests developed to obtain the best diagnoses. All of the tests are classified and described in terms of the characteristics of the data obtained. 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Tax</name></author></analytic></biblStruct></listBibl></div1></back></TEI></pmc><pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">DIMETER: a haptic master device for tremor diagnosis in neurodegenerative diseases.</title><author><name sortKey="Gonzalez, Roberto" sort="Gonzalez, Roberto" uniqKey="Gonzalez R" first="Roberto" last="González">Roberto González</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain. roberto.gonzalez@upm.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Barrientos, Antonio" sort="Barrientos, Antonio" uniqKey="Barrientos A" first="Antonio" last="Barrientos">Antonio Barrientos</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain. antonio.barrientos@upm.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Del Cerro, Jaime" sort="Del Cerro, Jaime" uniqKey="Del Cerro J" first="Jaime" last="Del Cerro">Jaime Del Cerro</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain. j.cerro@upm.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Coca, Benito" sort="Coca, Benito" uniqKey="Coca B" first="Benito" last="Coca">Benito Coca</name><affiliation wicri:level="2"><nlm:affiliation>ETSIDI-UPM, C/Ronda de Valencia 3, E-28012 Madrid, Spain. benitomaria.coca.hernandez@alumnos.upm.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>ETSIDI-UPM, C/Ronda de Valencia 3, E-28012 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="doi">10.3390/s140304536</idno><idno type="RBID">pubmed:24608001</idno><idno type="pmid">24608001</idno><idno type="wicri:Area/PubMed/Corpus">000726</idno><idno type="wicri:Area/PubMed/Curation">000726</idno><idno type="wicri:Area/PubMed/Checkpoint">000688</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">DIMETER: a haptic master device for tremor diagnosis in neurodegenerative diseases.</title><author><name sortKey="Gonzalez, Roberto" sort="Gonzalez, Roberto" uniqKey="Gonzalez R" first="Roberto" last="González">Roberto González</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain. roberto.gonzalez@upm.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Barrientos, Antonio" sort="Barrientos, Antonio" uniqKey="Barrientos A" first="Antonio" last="Barrientos">Antonio Barrientos</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain. antonio.barrientos@upm.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Del Cerro, Jaime" sort="Del Cerro, Jaime" uniqKey="Del Cerro J" first="Jaime" last="Del Cerro">Jaime Del Cerro</name><affiliation wicri:level="2"><nlm:affiliation>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid, Spain. j.cerro@upm.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Centre for Automation and Robotics UPM-CSIC, C/José Gutierrez Abascal 2, E-28006 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Coca, Benito" sort="Coca, Benito" uniqKey="Coca B" first="Benito" last="Coca">Benito Coca</name><affiliation wicri:level="2"><nlm:affiliation>ETSIDI-UPM, C/Ronda de Valencia 3, E-28012 Madrid, Spain. benitomaria.coca.hernandez@alumnos.upm.es.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>ETSIDI-UPM, C/Ronda de Valencia 3, E-28012 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region></placeName></affiliation></author></analytic><series><title level="j">Sensors (Basel, Switzerland)</title><idno type="eISSN">1424-8220</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomechanical Phenomena</term><term>Diagnostic Techniques, Neurological (instrumentation)</term><term>Humans</term><term>Movement</term><term>Neural Networks (Computer)</term><term>Neurodegenerative Diseases (diagnosis)</term><term>Pattern Recognition, Automated</term><term>Software</term><term>Touch</term><term>Tremor (diagnosis)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Neurodegenerative Diseases</term><term>Tremor</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Diagnostic Techniques, Neurological</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biomechanical Phenomena</term><term>Humans</term><term>Movement</term><term>Neural Networks (Computer)</term><term>Pattern Recognition, Automated</term><term>Software</term><term>Touch</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In this study, a device based on patient motion capture is developed for the reliable and non-invasive diagnosis of neurodegenerative diseases. The primary objective of this study is the classification of differential diagnosis between Parkinson's disease (PD) and essential tremor (ET). The DIMETER system has been used in the diagnoses of a significant number of patients at two medical centers in Spain. Research studies on classification have primarily focused on the use of well-known and reliable diagnosis criteria developed by qualified personnel. Here, we first present a literature review of the methods used to detect and evaluate tremor; then, we describe the DIMETER device in terms of the software and hardware used and the battery of tests developed to obtain the best diagnoses. All of the tests are classified and described in terms of the characteristics of the data obtained. A list of parameters obtained from the tests is provided, and the results obtained using multilayer perceptron (MLP) neural networks are presented and analyzed.</div></front></TEI></pubmed></double></record>Pour manipuler ce document sous Unix (Dilib)
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