Pigment dispersion syndrome associated with intraocular lens implantation: a new surgical technique
Identifieur interne : 001806 ( Ncbi/Merge ); précédent : 001805; suivant : 001807Pigment dispersion syndrome associated with intraocular lens implantation: a new surgical technique
Auteurs : M Isabel Canut Jordana [Espagne] ; Daniel Pérez Formig [Espagne] ; Rodrigo Abreu González [Espagne] ; Jeroni Nadal Reus [Espagne]Source :
- Clinical Ophthalmology (Auckland, N.Z.) [ 1177-5467 ] ; 2010.
Abstract
We report the case of a myopic patient who, after intraocular lens transplant in the posterior chamber, suffered elevated intraocular pressure due to pigment dispersion, with recurrent episodes of blurred vision. The patient was treated with a new surgical technique that can avoid potential iridolenticular contact.
Complete ophthalmologic examination and optical coherence tomography (OCT) of the anterior segment were performed.
Contact between the pigmentary epithelium and the iris with an intraocular lens was revealed by utrasound biomicroscopy and OCT. In this case, Nd:YAG laser iridotomy and laser iridoplasty were not effective for iridolenticular separation and control of the pigment dispersion. We propose a new technique: stitches on the surface of the iris to obtain good iridolenticular separation and good intraocular pressure control.
Stitches on the iris surface should be considered as optional therapy in pigmentary glaucoma secondary to intraocular lens implantation. This surgical technique can avoid potential iridolenticular contacts more definitively.
Url:
DOI: 10.2147/OPTH.S14361
PubMed: 21151331
PubMed Central: 2993126
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Pigment dispersion syndrome associated with intraocular lens implantation: a new surgical technique</title><author><name sortKey="Jordana, M Isabel Canut" sort="Jordana, M Isabel Canut" uniqKey="Jordana M" first="M Isabel Canut" last="Jordana">M Isabel Canut Jordana</name><affiliation wicri:level="3"><nlm:aff id="af1-opth-4-1263"> Barraquer Ophthalmology Centre, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Barraquer Ophthalmology Centre, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Formig, Daniel Perez" sort="Formig, Daniel Perez" uniqKey="Formig D" first="Daniel Pérez" last="Formig">Daniel Pérez Formig</name><affiliation wicri:level="3"><nlm:aff id="af1-opth-4-1263"> Barraquer Ophthalmology Centre, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Barraquer Ophthalmology Centre, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Gonzalez, Rodrigo Abreu" sort="Gonzalez, Rodrigo Abreu" uniqKey="Gonzalez R" first="Rodrigo Abreu" last="González">Rodrigo Abreu González</name><affiliation wicri:level="1"><nlm:aff id="af2-opth-4-1263"> University Hospital of La Candelaria, Tenerife, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> University Hospital of La Candelaria, Tenerife</wicri:regionArea><wicri:noRegion>Tenerife</wicri:noRegion></affiliation></author><author><name sortKey="Reus, Jeroni Nadal" sort="Reus, Jeroni Nadal" uniqKey="Reus J" first="Jeroni Nadal" last="Reus">Jeroni Nadal Reus</name><affiliation wicri:level="3"><nlm:aff id="af1-opth-4-1263"> Barraquer Ophthalmology Centre, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Barraquer Ophthalmology Centre, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21151331</idno><idno type="pmc">2993126</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993126</idno><idno type="RBID">PMC:2993126</idno><idno type="doi">10.2147/OPTH.S14361</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">000C84</idno><idno type="wicri:Area/Pmc/Curation">000C84</idno><idno type="wicri:Area/Pmc/Checkpoint">001D94</idno><idno type="wicri:Area/Ncbi/Merge">001806</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Pigment dispersion syndrome associated with intraocular lens implantation: a new surgical technique</title><author><name sortKey="Jordana, M Isabel Canut" sort="Jordana, M Isabel Canut" uniqKey="Jordana M" first="M Isabel Canut" last="Jordana">M Isabel Canut Jordana</name><affiliation wicri:level="3"><nlm:aff id="af1-opth-4-1263"> Barraquer Ophthalmology Centre, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Barraquer Ophthalmology Centre, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Formig, Daniel Perez" sort="Formig, Daniel Perez" uniqKey="Formig D" first="Daniel Pérez" last="Formig">Daniel Pérez Formig</name><affiliation wicri:level="3"><nlm:aff id="af1-opth-4-1263"> Barraquer Ophthalmology Centre, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Barraquer Ophthalmology Centre, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Gonzalez, Rodrigo Abreu" sort="Gonzalez, Rodrigo Abreu" uniqKey="Gonzalez R" first="Rodrigo Abreu" last="González">Rodrigo Abreu González</name><affiliation wicri:level="1"><nlm:aff id="af2-opth-4-1263"> University Hospital of La Candelaria, Tenerife, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> University Hospital of La Candelaria, Tenerife</wicri:regionArea><wicri:noRegion>Tenerife</wicri:noRegion></affiliation></author><author><name sortKey="Reus, Jeroni Nadal" sort="Reus, Jeroni Nadal" uniqKey="Reus J" first="Jeroni Nadal" last="Reus">Jeroni Nadal Reus</name><affiliation wicri:level="3"><nlm:aff id="af1-opth-4-1263"> Barraquer Ophthalmology Centre, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea> Barraquer Ophthalmology Centre, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author></analytic><series><title level="j">Clinical Ophthalmology (Auckland, N.Z.)</title><idno type="ISSN">1177-5467</idno><idno type="eISSN">1177-5483</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Aims</title><p>We report the case of a myopic patient who, after intraocular lens transplant in the posterior chamber, suffered elevated intraocular pressure due to pigment dispersion, with recurrent episodes of blurred vision. The patient was treated with a new surgical technique that can avoid potential iridolenticular contact.</p></sec><sec><title>Methods</title><p>Complete ophthalmologic examination and optical coherence tomography (OCT) of the anterior segment were performed.</p></sec><sec><title>Results</title><p>Contact between the pigmentary epithelium and the iris with an intraocular lens was revealed by utrasound biomicroscopy and OCT. In this case, Nd:YAG laser iridotomy and laser iridoplasty were not effective for iridolenticular separation and control of the pigment dispersion. We propose a new technique: stitches on the surface of the iris to obtain good iridolenticular separation and good intraocular pressure control.</p></sec><sec><title>Conclusion</title><p>Stitches on the iris surface should be considered as optional therapy in pigmentary glaucoma secondary to intraocular lens implantation. This surgical technique can avoid potential iridolenticular contacts more definitively.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Detry Morel, Ml" uniqKey="Detry Morel M">ML Detry-Morel</name></author><author><name sortKey="Van Acker, E" uniqKey="Van Acker E">E van Acker</name></author><author><name sortKey="Pourjavan, S" uniqKey="Pourjavan S">S Pourjavan</name></author><author><name sortKey="Levi, N" uniqKey="Levi N">N Levi</name></author><author><name sortKey="De Potter, P" uniqKey="De Potter P">P de Potter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brandt, Jd" uniqKey="Brandt J">JD Brandt</name></author><author><name sortKey="Mockovak, Me" uniqKey="Mockovak M">ME Mockovak</name></author><author><name sortKey="Chayet, A" uniqKey="Chayet A">A Chayet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ballin, N" uniqKey="Ballin N">N Ballin</name></author><author><name sortKey="Weiss, Dm" uniqKey="Weiss D">DM Weiss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Puliafito, Ca" uniqKey="Puliafito C">CA Puliafito</name></author><author><name sortKey="Hee, Mr" uniqKey="Hee M">MR Hee</name></author><author><name sortKey="Schuman, Js" uniqKey="Schuman J">JS Schuman</name></author><author><name sortKey="Fujimoto, Jg" uniqKey="Fujimoto J">JG Fujimoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mendez Hernandez, C" uniqKey="Mendez Hernandez C">C Méndez-Hernandez</name></author><author><name sortKey="Garcia Feijo, J" uniqKey="Garcia Feijo J">J García-Feijoó</name></author><author><name sortKey="Cui A Sardi A, R" uniqKey="Cui A Sardi A R">R Cuiña-Sardiña</name></author><author><name sortKey="Garcia Sanchez, J" uniqKey="Garcia Sanchez J">J García-Sánchez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Potash, Sd" uniqKey="Potash S">SD Potash</name></author><author><name sortKey="Tello, C" uniqKey="Tello C">C Tello</name></author><author><name sortKey="Liebmann, J" uniqKey="Liebmann J">J Liebmann</name></author><author><name sortKey="Richt, R" uniqKey="Richt R">R Richt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chang, Wh" uniqKey="Chang W">WH Chang</name></author><author><name sortKey="Werner, L" uniqKey="Werner L">L Werner</name></author><author><name sortKey="Fry, Ll" uniqKey="Fry L">LL Fry</name></author><author><name sortKey="Johnson, Jt" uniqKey="Johnson J">JT Johnson</name></author><author><name sortKey="Kamae, K" uniqKey="Kamae K">K Kamae</name></author><author><name sortKey="Mamalis, N" uniqKey="Mamalis N">N Mamalis</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chang, Shl" uniqKey="Chang S">SHL Chang</name></author><author><name sortKey="Lim, G" uniqKey="Lim G">G Lim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kohnen, T" uniqKey="Kohnen T">T Kohnen</name></author><author><name sortKey="Kook, D" uniqKey="Kook D">D Kook</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Ophthalmol</journal-id><journal-id journal-id-type="publisher-id">Clinical Ophthalmology</journal-id><journal-title-group><journal-title>Clinical Ophthalmology (Auckland, N.Z.)</journal-title></journal-title-group><issn pub-type="ppub">1177-5467</issn><issn pub-type="epub">1177-5483</issn><publisher><publisher-name>Dove Medical Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21151331</article-id><article-id pub-id-type="pmc">2993126</article-id><article-id pub-id-type="doi">10.2147/OPTH.S14361</article-id><article-id pub-id-type="publisher-id">opth-4-1263</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Pigment dispersion syndrome associated with intraocular lens implantation: a new surgical technique</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Jordana</surname><given-names>M Isabel Canut</given-names></name><name content-type="index"><surname>Canut</surname><given-names>MI</given-names></name><xref ref-type="aff" rid="af1-opth-4-1263">1</xref><xref ref-type="corresp" rid="c1-opth-4-1263"></xref></contrib><contrib contrib-type="author"><name><surname>Formigó</surname><given-names>Daniel Pérez</given-names></name><name content-type="index"><surname>Pérez</surname><given-names>D</given-names></name><xref ref-type="aff" rid="af1-opth-4-1263">1</xref></contrib><contrib contrib-type="author"><name><surname>González</surname><given-names>Rodrigo Abreu</given-names></name><name content-type="index"><surname>Abreu</surname><given-names>R</given-names></name><xref ref-type="aff" rid="af2-opth-4-1263">2</xref></contrib><contrib contrib-type="author"><name><surname>Reus</surname><given-names>Jeroni Nadal</given-names></name><name content-type="index"><surname>Nadal</surname><given-names>J</given-names></name><xref ref-type="aff" rid="af1-opth-4-1263">1</xref></contrib></contrib-group><aff id="af1-opth-4-1263"><label>1</label> Barraquer Ophthalmology Centre, Barcelona, Spain</aff><aff id="af2-opth-4-1263"><label>2</label> University Hospital of La Candelaria, Tenerife, Spain</aff><author-notes><corresp id="c1-opth-4-1263">Correspondence: MI Canut Jordana, c/ Muntaner 314, 08021, Barcelona, Spain, Tel +34 620 21 20 21, Fax +34 932 002 469, Email <email>mcanut@co-barraquer.es</email></corresp></author-notes><pub-date pub-type="collection"><year>2010</year></pub-date><pmc-comment>Dove Press titles changed from ppub to collections in 2009.
Fake ppub written to satisfy Coll Date Type=ppub</pmc-comment>
<pub-date pub-type="ppub"><year>2010</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2010</year></pub-date><volume>4</volume><fpage>1263</fpage><lpage>1266</lpage><permissions><copyright-statement>© 2010 Canut Jordana et al, publisher and licensee Dove Medical Press Ltd.</copyright-statement><license><license-p>This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.</license-p></license></permissions><abstract><sec><title>Aims</title><p>We report the case of a myopic patient who, after intraocular lens transplant in the posterior chamber, suffered elevated intraocular pressure due to pigment dispersion, with recurrent episodes of blurred vision. The patient was treated with a new surgical technique that can avoid potential iridolenticular contact.</p></sec><sec><title>Methods</title><p>Complete ophthalmologic examination and optical coherence tomography (OCT) of the anterior segment were performed.</p></sec><sec><title>Results</title><p>Contact between the pigmentary epithelium and the iris with an intraocular lens was revealed by utrasound biomicroscopy and OCT. In this case, Nd:YAG laser iridotomy and laser iridoplasty were not effective for iridolenticular separation and control of the pigment dispersion. We propose a new technique: stitches on the surface of the iris to obtain good iridolenticular separation and good intraocular pressure control.</p></sec><sec><title>Conclusion</title><p>Stitches on the iris surface should be considered as optional therapy in pigmentary glaucoma secondary to intraocular lens implantation. This surgical technique can avoid potential iridolenticular contacts more definitively.</p></sec></abstract><kwd-group><kwd>pigmentary glaucoma</kwd><kwd>intraocular lens</kwd><kwd>optical coherence tomography</kwd><kwd>laser</kwd></kwd-group></article-meta></front><body><sec sec-type="intro"><title>Introduction</title><p>Pigmentary dispersion syndrome secondary to intraocular lens (IOL) implantation in the sulcus may be a potential problem with poor response to medical treatment.<xref ref-type="bibr" rid="b1-opth-4-1263">1</xref>–<xref ref-type="bibr" rid="b4-opth-4-1263">4</xref> Good results have been obtained with Nd:Yag laser peripheral iridotomy and with argon laser iridoplasty.<xref ref-type="bibr" rid="b5-opth-4-1263">5</xref>,<xref ref-type="bibr" rid="b6-opth-4-1263">6</xref></p><p>We report a case with poor response to conventional treatment, in which we developed a new surgical procedure by suturing the iris surface with prolene stitches in the iridolenticular contact zone.</p></sec><sec sec-type="cases"><title>Case report</title><p>A 61-years-old woman, surgically treated for right eye cataract 30 months before, attended the emergency department for blurred vision after trauma.</p><p>Biomicroscopic examination of the anterior segment revealed pseudophakia with small slight displacement of the IOL towards the nasal quadrant and marked iridopseudophakodonesis, tyndal positive, flare +3, and retrolental pigment without evidence of vitreous in the anterior chamber. Gonioscopy showed an open angle with pigment deposits from 5 to 7 hours. Right eye intraocular pressure (IOP) was 26 mmHg. The posterior segment showed myopic fundus and uncorrected visual acuity was 0.65. Left eye biomicroscopic examination showed a posterior chamber IOL, no pigment dispersion, and a open angle without evident trabecular pigmentation.</p><p>We observed a good response with timolol 0.5% (Timoftol<sup>®</sup>; MSD Laboratories, Whitehouse Station, NJ) and topical prednisolone acetate (Pred-Forte<sup>®</sup>; Allergan Laboratories, Irvine, CA) administered twice daily for two weeks. One month later, tyndall was negative and IOP was 12 mmHg.</p><p>Two months later the patient attended our emergency department again. We observed a luxated IOL in the vitreous cavity. We therefore decided to perform a vitrectomy, relocation of the IOL to the anterior chamber, and extraction since this was an IOL with three points of support (Ioltech Stabibag hydro-philic intraocular lens; Bausch and Lomb, Rochester, NY), and scleral-sutured posterior chamber intraocular lens implantation (+4.00 D MA60MA Acrysoft<sup>®</sup>IOL; Alcon Laboratories, Fort Worth, TX).</p><p>Immediately after intervention we observed satisfactory evolution with the IOL in position and IOP of 18 mmHg.</p><p>At one and three months after IOL replacement, the patient suffered two episodes of intraocular hypertension. Both biomicroscopic examinations showed a wide chamber with pigment dispersion in the anterior chamber and a cornea with some old endothelial pigment. Intraocular pressures of, 30 and 50 mmHg respectively were satisfactorily treated with a fixed combination of dorzolamide and timoftol (Cosopt<sup>®</sup>; MSD Laboratories) and topical prednisolone acetate (Pred-Forte<sup>®</sup>; Allergan Laboratories) administered twice daily.</p><p>At six months after IOL replacement, the patient again attended our emergency department, this time complaining of blurred vision. Examination revealed abundant pigment dispersion throughout the anterior chamber, marked iris concavity, and untreated IOP of 14 mmHg (<xref ref-type="fig" rid="f1-opth-4-1263">Figure 1</xref>). We performed a macular ophthalmoscopy and optical coherence tomography to (OCT) (Visante<sup>®</sup>; Carl Zeiss Meditec, Inc., Jena, Germany) to look for a cystoid macular edema but no macular disorder was found. At this point we considered a possible diagnosis of pigment dispersion due to iridolenticular contact. OCT of the anterior segment showed iris concavity produced by contact between the posterior face of the iris and the anterior face of the crystalline lens (<xref ref-type="fig" rid="f2-opth-4-1263">Figure 2</xref>). This finding led to the performance of Nd:YAG laser iridotomy which rectified the iris concavity.</p><p>At successive check-ups we observed good iridolenticular separation in the right eye, permeable iridotomies, anterior chamber without celularity, and IOP of 10 mmHg.</p><p>Two months after Nd:YAG laser iridectomy, the patient reported a new episode of blurred vision. Examination showed extensive pigment dispersion in the anterior chamber, with right eye IOP of 12 mmHg. After two months of medical treatment (topical prednisolone acetate and tapered oral prednisone) without clinical improvement, we performed 360° iridoplasty of the peripheral iris, which achieved good anatomic resolution but required maintenance therapy with antiglaucoma medication and topical nonsteroidal anti-inflamatory drugs to conserve good visual acuity. Pilocarpine eye drops were used previously to check the contractility of the iris, finding a poor response.</p><p>Twelve months after the iridoplasty, the patient had new episodes of blurred vision caused by dispersion of pigment in the anterior chamber, which was resolved with nonsteroidal anti-inflammatory drugs and topical beta blockers (<xref ref-type="fig" rid="f3-opth-4-1263">Figure 3</xref>). A repeat OCT of the anterior segment showed iridolenticular contact.</p><p>Given the chronic nature of the case and the refusal of the patient to undergo IOL removal or repositioning of the IOL in the anterior chamber despite good endothelial cell count, we decided to perform a more conservative surgery consisting of placing four prolene 10/0 stitches (Ethicon Inc, Somerville, NJ) on the iris surface to permanently remove the iridolenticular contact (<xref ref-type="fig" rid="f4-opth-4-1263">Figure 4</xref>). The technique consists of performing three paracentesis, two of them in each of the margins of the area affected by the pigment dispersion, and a third at the midpoint. In this way we could access the area to be treated by adjusting the different stitches and were thus able to lift the flaccid iris, and eliminate the iridolenticular contacts.</p><p>Six months after placement of the prolene stitches in the iris, we observed good tolerance (<xref ref-type="fig" rid="f5-opth-4-1263">Figure 5</xref>), an absence of pigment dispersion in anterior chamber, and a good iridolenticular separation in the OCT (<xref ref-type="fig" rid="f6-opth-4-1263">Figure 6</xref>). Without antiglaucoma medication, uncorrected visual acuity was 0.65, and an IOP of 17 mmHg.</p></sec><sec sec-type="discussion"><title>Discussion</title><p>Pigment dispersion syndrome (PDS) is produced when iris pigmentary epithelium pigment deposits pass through the aqueous humor and are dispersed throughout the anterior segment. When this dispersion is associated with increased IOP, it is called pigmentary glaucoma (PG), which must be taken into account on evaluating primary open-angle glaucoma.<xref ref-type="bibr" rid="b1-opth-4-1263">1</xref></p><p>The literature contains cases of PG secondary to IOL implantation in the posterior chamber. Among the different theories attempting to explain this increase of IOP, the most widely accepted proposes that chronic contact between the haptics and the posterior face of the iris triggers pigment release. This, together with the localization of iris transillumination defects and increased IOP months after intervention, suggests that the IOL is the most probable cause.<xref ref-type="bibr" rid="b2-opth-4-1263">2</xref> The thickness, size, material, implantation technique, and the degree of inclination of the haptics are factors that influence changes in the iris.<xref ref-type="bibr" rid="b3-opth-4-1263">3</xref></p><p>Anterior segment optical coherence tomography (AS-OCT) is a high resolution noninvasive technique allowing rapid in vivo evaluation of possible iridolenticular contact, as well as visualization of anatomic details such as iris concavity, amplitude, and angle of the anterior chamber.<xref ref-type="bibr" rid="b4-opth-4-1263">4</xref>,<xref ref-type="bibr" rid="b5-opth-4-1263">5</xref></p><p>In order to equalize anterior and posterior chamber pressure, many authors propose the use of Nd:YAG laser iridotomy, with confirmation of iris flattening by ultrasound biomicroscopy. Although most cases prove anatomically successful (with restitution of the iris in its anatomic position), pressure control is often not achieved. This explains why the efficacy of YAG laser iridotomy in pigmentary glaucoma is not generally established.<xref ref-type="bibr" rid="b6-opth-4-1263">6</xref></p><p>Considering the physiopathologic mechanisms of pigmentary glaucoma and the mechanism of action of argon laser iridoplasty (which aims to provoke contraction of the peripheral iris and flattening of the peripheral curvature using the thermal effect of the laser), we believe that this method could be useful for this type of pathology, reducing iris concavity and avoiding “reverse pupillary block” and the consequent increase of intraocular pressure. However, this hypothesis requires prolonged studies with greater numbers of patients to determine its possible indication and long-term benefits.</p><p>Pigment dispersion syndrome secondary to IOL implantation in the sulcus and mainly if haptic-optic angulation is present as in the case described (MA60MA Acrysoft<sup>®</sup> IOL, Alcon Labs) may prove refractory to medical treatment and require coadjuvant laser treatment (such as iridotomy or iridoplasty), to correct episodes of pigment dispersion by minimizing iris-optic and iris-haptic contact.</p><p>When the laser treatment is not sufficient to reverse this process, different authors propose explants or IOL exchange to solve the pigment dispersion.<xref ref-type="bibr" rid="b7-opth-4-1263">7</xref>–<xref ref-type="bibr" rid="b10-opth-4-1263">10</xref> In our case, the refusal of the patient to agree to IOL removal and due to the clearly identified iridolenticular contact, we decided to perform surgery that involved stitches to the surface of the iris in order to lift the iris and separate it from the IOL. As this is a new technique, we need more follow-up time and a larger series of patients, to confirm this method as an alternative surgical treatment when conventional laser (iridotomy and iridoplasty) does not resolve the iridolenticular contact.</p><p>If the stitches do not suceed, we propose removal of the IOL to prevent chronic evolution of pigment loss.</p></sec></body><back><fn-group><fn><p><bold>Disclosure</bold></p><p>No conflicts of interest were declared in relation to this paper.</p></fn></fn-group><ref-list><title>References</title><ref id="b1-opth-4-1263"><label>1</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Detry-Morel</surname><given-names>ML</given-names></name><name><surname>van Acker</surname><given-names>E</given-names></name><name><surname>Pourjavan</surname><given-names>S</given-names></name><name><surname>Levi</surname><given-names>N</given-names></name><name><surname>de 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Case report with clinicopathological correlation</article-title><source>J Cataract Refract Surg</source><year>2007</year><volume>33</volume><issue>6</issue><fpage>1106</fpage><lpage>1109</lpage><pub-id pub-id-type="pmid">17531710</pub-id></mixed-citation></ref><ref id="b8-opth-4-1263"><label>8</label><mixed-citation publication-type="journal"><collab>ASCRS Cataract Clinical Committee</collab><article-title>Complications of sulcus placement of single-piece acrylic intraocular lenses: recommendations for backup IOL implantation following posterior capsule rupture</article-title><source>J Cataract Refract Surg</source><year>2009</year><volume>35</volume><issue>8</issue><fpage>1445</fpage><lpage>1458</lpage><pub-id pub-id-type="pmid">19631134</pub-id></mixed-citation></ref><ref id="b9-opth-4-1263"><label>9</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Chang</surname><given-names>SHL</given-names></name><name><surname>Lim</surname><given-names>G</given-names></name></person-group><article-title>Secondary pigmentary glaucoma associated with piggyback intraocular lens implantation</article-title><source>J Cataract Refract Surg</source><year>2004</year><volume>30</volume><fpage>2219</fpage><lpage>2222</lpage><pub-id pub-id-type="pmid">15474839</pub-id></mixed-citation></ref><ref id="b10-opth-4-1263"><label>10</label><mixed-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kohnen</surname><given-names>T</given-names></name><name><surname>Kook</surname><given-names>D</given-names></name></person-group><article-title>Solving intraocular lens-related pigment dispersion syndrome with repositioning of primary sulcus implanted single-piece IOL in the capsular bag</article-title><source>J Cataract Refract Surg</source><year>2009</year><volume>35</volume><issue>8</issue><fpage>1459</fpage><lpage>1463</lpage><pub-id pub-id-type="pmid">19631135</pub-id></mixed-citation></ref></ref-list></back><floats-group><fig id="f1-opth-4-1263" position="float"><label>Figure 1</label><caption><p>Intense pigment dispersion in the anterior chamber and large chamber amplitude after intraocular lens replacement.</p></caption><graphic xlink:href="opth-4-1263f1"></graphic></fig><fig id="f2-opth-4-1263" position="float"><label>Figure 2</label><caption><p>Photocomposition of optical coherence tomography images of the anterior segment. Note the pronounced iris concavity, the reverse pupillary block, and the iridolenticular contact that produced pigment dispersion.</p></caption><graphic xlink:href="opth-4-1263f2"></graphic></fig><fig id="f3-opth-4-1263" position="float"><label>Figure 3</label><caption><p>Iris transillumination in slit lamp examination, clearly showing pigmentary defect in the areas of chronic rubbing due to iridolenticular and intraocular lens haptic contact with the posterior face of the iris.</p></caption><graphic xlink:href="opth-4-1263f3"></graphic></fig><fig id="f4-opth-4-1263" position="float"><label>Figure 4</label><caption><p>Details of the placement of prolene stitches in the area of the iris that we raised to avoid iridolenticular contact.</p></caption><graphic xlink:href="opth-4-1263f4"></graphic></fig><fig id="f5-opth-4-1263" position="float"><label>Figure 5</label><caption><p>Six months later. Anterior chamber without pigment dispersion and iris prolene stitches well tolerated at 7, 9, and 11 hours.</p></caption><graphic xlink:href="opth-4-1263f5"></graphic></fig><fig id="f6-opth-4-1263" position="float"><label>Figure 6</label><caption><p>Detail showing iridolenticular separation after prolene 10/0 stitches optical coherence tomography.</p></caption><graphic xlink:href="opth-4-1263f6"></graphic></fig></floats-group></pmc><affiliations><list><country><li>Espagne</li></country><region><li>Catalogne</li></region><settlement><li>Barcelone</li></settlement></list><tree><country name="Espagne"><region name="Catalogne"><name sortKey="Jordana, M Isabel Canut" sort="Jordana, M Isabel Canut" uniqKey="Jordana M" first="M Isabel Canut" last="Jordana">M Isabel Canut Jordana</name></region><name sortKey="Formig, Daniel Perez" sort="Formig, Daniel Perez" uniqKey="Formig D" first="Daniel Pérez" last="Formig">Daniel Pérez Formig</name><name sortKey="Gonzalez, Rodrigo Abreu" sort="Gonzalez, Rodrigo Abreu" uniqKey="Gonzalez R" first="Rodrigo Abreu" last="González">Rodrigo Abreu González</name><name sortKey="Reus, Jeroni Nadal" sort="Reus, Jeroni Nadal" uniqKey="Reus J" first="Jeroni Nadal" last="Reus">Jeroni Nadal Reus</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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