Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale
Identifieur interne : 003352 ( Ncbi/Curation ); précédent : 003351; suivant : 003353Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale
Auteurs : Yaokun Zhang [Allemagne] ; Tom Pfeiffer [Allemagne] ; Marcel Weller [Allemagne] ; Wolfgang Wieser [Allemagne] ; Robert Huber [Allemagne] ; Jörg Raczkowsky [Allemagne] ; Jörg Schipper [Allemagne] ; Heinz Wörn [Allemagne] ; Thomas Klenzner [Allemagne]Source :
- BioMed Research International [ 2314-6133 ] ; 2014.
Abstract
Lasers have been proven to be precise tools for bone ablation. Applying no mechanical stress to the patient, they are potentially very suitable for microsurgery on fragile structures such as the inner ear. However, it remains challenging to control the laser-bone ablation without injuring embedded soft tissue. In this work, we demonstrate a closed-loop control of a short-pulsed CO2 laser to perform laser cochleostomy under the monitoring of an optical coherence tomography (OCT) system. A foresighted detection of the bone-endosteum-perilymph boundary several hundred micrometers before its exposure has been realized. Position and duration of the laser pulses are planned based on the residual bone thickness distribution. OCT itself is also used as a highly accurate tracking system for motion compensation between the target area and the optics. During
Url:
DOI: 10.1155/2014/251814
PubMed: 25295253
PubMed Central: 4177734
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001C15
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :001C15
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000A59
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :003352
Links to Exploration step
PMC:4177734Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale</title><author><name sortKey="Zhang, Yaokun" sort="Zhang, Yaokun" uniqKey="Zhang Y" first="Yaokun" last="Zhang">Yaokun Zhang</name><affiliation wicri:level="3"><nlm:aff id="I1">Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Pfeiffer, Tom" sort="Pfeiffer, Tom" uniqKey="Pfeiffer T" first="Tom" last="Pfeiffer">Tom Pfeiffer</name><affiliation wicri:level="4"><nlm:aff id="I2">Ludwig-Maximilians-University, Oettingenstraße 67, 80538 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Ludwig-Maximilians-University, Oettingenstraße 67, 80538 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Weller, Marcel" sort="Weller, Marcel" uniqKey="Weller M" first="Marcel" last="Weller">Marcel Weller</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf</wicri:regionArea><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Wieser, Wolfgang" sort="Wieser, Wolfgang" uniqKey="Wieser W" first="Wolfgang" last="Wieser">Wolfgang Wieser</name><affiliation wicri:level="4"><nlm:aff id="I2">Ludwig-Maximilians-University, Oettingenstraße 67, 80538 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Ludwig-Maximilians-University, Oettingenstraße 67, 80538 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Huber, Robert" sort="Huber, Robert" uniqKey="Huber R" first="Robert" last="Huber">Robert Huber</name><affiliation wicri:level="1"><nlm:aff id="I4">Institute for Biomedical Optics, University of Lübeck, Gebäude 81, Raum R 67, Peter-Monnik-Weg 4, 23562 Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Biomedical Optics, University of Lübeck, Gebäude 81, Raum R 67, Peter-Monnik-Weg 4, 23562 Lübeck</wicri:regionArea><wicri:noRegion>23562 Lübeck</wicri:noRegion><wicri:noRegion>23562 Lübeck</wicri:noRegion><wicri:noRegion>23562 Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Raczkowsky, Jorg" sort="Raczkowsky, Jorg" uniqKey="Raczkowsky J" first="Jörg" last="Raczkowsky">Jörg Raczkowsky</name><affiliation wicri:level="3"><nlm:aff id="I1">Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Schipper, Jorg" sort="Schipper, Jorg" uniqKey="Schipper J" first="Jörg" last="Schipper">Jörg Schipper</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf</wicri:regionArea><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Worn, Heinz" sort="Worn, Heinz" uniqKey="Worn H" first="Heinz" last="Wörn">Heinz Wörn</name><affiliation wicri:level="3"><nlm:aff id="I1">Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Klenzner, Thomas" sort="Klenzner, Thomas" uniqKey="Klenzner T" first="Thomas" last="Klenzner">Thomas Klenzner</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf</wicri:regionArea><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25295253</idno><idno type="pmc">4177734</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177734</idno><idno type="RBID">PMC:4177734</idno><idno type="doi">10.1155/2014/251814</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001C15</idno><idno type="wicri:Area/Pmc/Curation">001C15</idno><idno type="wicri:Area/Pmc/Checkpoint">000A59</idno><idno type="wicri:Area/Ncbi/Merge">003352</idno><idno type="wicri:Area/Ncbi/Curation">003352</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale</title><author><name sortKey="Zhang, Yaokun" sort="Zhang, Yaokun" uniqKey="Zhang Y" first="Yaokun" last="Zhang">Yaokun Zhang</name><affiliation wicri:level="3"><nlm:aff id="I1">Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Pfeiffer, Tom" sort="Pfeiffer, Tom" uniqKey="Pfeiffer T" first="Tom" last="Pfeiffer">Tom Pfeiffer</name><affiliation wicri:level="4"><nlm:aff id="I2">Ludwig-Maximilians-University, Oettingenstraße 67, 80538 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Ludwig-Maximilians-University, Oettingenstraße 67, 80538 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Weller, Marcel" sort="Weller, Marcel" uniqKey="Weller M" first="Marcel" last="Weller">Marcel Weller</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf</wicri:regionArea><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Wieser, Wolfgang" sort="Wieser, Wolfgang" uniqKey="Wieser W" first="Wolfgang" last="Wieser">Wolfgang Wieser</name><affiliation wicri:level="4"><nlm:aff id="I2">Ludwig-Maximilians-University, Oettingenstraße 67, 80538 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Ludwig-Maximilians-University, Oettingenstraße 67, 80538 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Huber, Robert" sort="Huber, Robert" uniqKey="Huber R" first="Robert" last="Huber">Robert Huber</name><affiliation wicri:level="1"><nlm:aff id="I4">Institute for Biomedical Optics, University of Lübeck, Gebäude 81, Raum R 67, Peter-Monnik-Weg 4, 23562 Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Biomedical Optics, University of Lübeck, Gebäude 81, Raum R 67, Peter-Monnik-Weg 4, 23562 Lübeck</wicri:regionArea><wicri:noRegion>23562 Lübeck</wicri:noRegion><wicri:noRegion>23562 Lübeck</wicri:noRegion><wicri:noRegion>23562 Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Raczkowsky, Jorg" sort="Raczkowsky, Jorg" uniqKey="Raczkowsky J" first="Jörg" last="Raczkowsky">Jörg Raczkowsky</name><affiliation wicri:level="3"><nlm:aff id="I1">Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Schipper, Jorg" sort="Schipper, Jorg" uniqKey="Schipper J" first="Jörg" last="Schipper">Jörg Schipper</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf</wicri:regionArea><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Worn, Heinz" sort="Worn, Heinz" uniqKey="Worn H" first="Heinz" last="Wörn">Heinz Wörn</name><affiliation wicri:level="3"><nlm:aff id="I1">Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Anthropomatics and Robotics (IAR)-Intelligent Process Control and Robotics (IPR), KIT, Engler-Bunte-Ring 8, 76131 Karlsruhe</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Karlsruhe</settlement></placeName></affiliation></author><author><name sortKey="Klenzner, Thomas" sort="Klenzner, Thomas" uniqKey="Klenzner T" first="Thomas" last="Klenzner">Thomas Klenzner</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Otorhinolaryngology, Düsseldorf University Hospital, Moorenstraße 5, 40225 Düsseldorf</wicri:regionArea><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion><wicri:noRegion>40225 Düsseldorf</wicri:noRegion></affiliation></author></analytic><series><title level="j">BioMed Research International</title><idno type="ISSN">2314-6133</idno><idno type="eISSN">2314-6141</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Lasers have been proven to be precise tools for bone ablation. Applying no mechanical stress to the patient, they are potentially very suitable for microsurgery on fragile structures such as the inner ear. However, it remains challenging to control the laser-bone ablation without injuring embedded soft tissue. In this work, we demonstrate a closed-loop control of a short-pulsed CO<sub>2</sub> laser to perform laser cochleostomy under the monitoring of an optical coherence tomography (OCT) system. A foresighted detection of the bone-endosteum-perilymph boundary several hundred micrometers before its exposure has been realized. Position and duration of the laser pulses are planned based on the residual bone thickness distribution. OCT itself is also used as a highly accurate tracking system for motion compensation between the target area and the optics. During<italic> ex vivo</italic> experimental evaluation on fresh porcine cochleae, the ablation process terminated automatically when the thickness of the residual tissue layer uniformly reached a predefined value. The shape of the resulting channel bottom converged to the natural curvature of the endosteal layer without injuring the critical structure. Preliminary measurements in OCT scans indicated that the mean absolute accuracy of the shape approximation was only around 20 <italic>μ</italic>m.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Klenzner, T" uniqKey="Klenzner T">T Klenzner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pararas, Eel" uniqKey="Pararas E">EEL Pararas</name></author><author><name sortKey="Borkholder, Da" uniqKey="Borkholder D">DA Borkholder</name></author><author><name sortKey="Borenstein, Jt" uniqKey="Borenstein J">JT Borenstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lenarz, T" uniqKey="Lenarz T">T Lenarz</name></author><author><name sortKey="James, C" uniqKey="James C">C James</name></author><author><name sortKey="Cuda, D" uniqKey="Cuda D">D Cuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roland, Ps" uniqKey="Roland P">PS Roland</name></author><author><name sortKey="Wright, Cg" uniqKey="Wright C">CG Wright</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Incerti, Pv" uniqKey="Incerti P">PV Incerti</name></author><author><name sortKey="Ching, Tyc" uniqKey="Ching T">TYC Ching</name></author><author><name sortKey="Cowan, R" uniqKey="Cowan R">R Cowan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klenzner, T" uniqKey="Klenzner T">T Klenzner</name></author><author><name sortKey="Ngan, C" uniqKey="Ngan C">C Ngan</name></author><author><name sortKey="Knapp, F" uniqKey="Knapp F">F Knapp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ngan, Cc" uniqKey="Ngan C">CC Ngan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Majdani, O" uniqKey="Majdani O">O Majdani</name></author><author><name sortKey="Rau, Ts" uniqKey="Rau T">TS Rau</name></author><author><name sortKey="Baron, S" uniqKey="Baron S">S Baron</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eilers, H" uniqKey="Eilers H">H Eilers</name></author><author><name sortKey="Baron, S" uniqKey="Baron S">S Baron</name></author><author><name sortKey="Ortmaier, T" uniqKey="Ortmaier T">T Ortmaier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Du, X" uniqKey="Du X">X Du</name></author><author><name sortKey="Assadi, Mz" uniqKey="Assadi M">MZ Assadi</name></author><author><name sortKey="Jowitt, F" uniqKey="Jowitt F">F Jowitt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brett, P" uniqKey="Brett P">P Brett</name></author><author><name sortKey="Du, X" uniqKey="Du X">X Du</name></author><author><name sortKey="Zoka Assadi, M" uniqKey="Zoka Assadi M">M Zoka-Assadi</name></author><author><name sortKey="Coulson, C" uniqKey="Coulson C">C Coulson</name></author><author><name sortKey="Reid, A" uniqKey="Reid A">A Reid</name></author><author><name sortKey="Proops, D" uniqKey="Proops D">D Proops</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frentzen, M" uniqKey="Frentzen M">M Frentzen</name></author><author><name sortKey="Gotz, W" uniqKey="Gotz W">W Götz</name></author><author><name sortKey="Ivanenko, M" uniqKey="Ivanenko M">M Ivanenko</name></author><author><name sortKey="Afilal, S" uniqKey="Afilal S">S Afilal</name></author><author><name sortKey="Werner, M" uniqKey="Werner M">M Werner</name></author><author><name sortKey="Hering, P" uniqKey="Hering P">P Hering</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ivanenko, M" uniqKey="Ivanenko M">M Ivanenko</name></author><author><name sortKey="Sader, R" uniqKey="Sader R">R Sader</name></author><author><name sortKey="Afilal, S" uniqKey="Afilal S">S Afilal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Werner, M" uniqKey="Werner M">M Werner</name></author><author><name sortKey="Ivanenko, M" uniqKey="Ivanenko M">M Ivanenko</name></author><author><name sortKey="Harbecke, D" uniqKey="Harbecke D">D Harbecke</name></author><author><name sortKey="Klasing, M" uniqKey="Klasing M">M Klasing</name></author><author><name sortKey="Steigerwald, H" uniqKey="Steigerwald H">H Steigerwald</name></author><author><name sortKey="Hering, P" uniqKey="Hering P">P Hering</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burgner, J" uniqKey="Burgner J">J Burgner</name></author><author><name sortKey="Muller, M" uniqKey="Muller M">M Müller</name></author><author><name sortKey="Raczkowsky, J" uniqKey="Raczkowsky J">J Raczkowsky</name></author><author><name sortKey="Worn, H" uniqKey="Worn H">H Wörn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fishman, Aj" uniqKey="Fishman A">AJ Fishman</name></author><author><name sortKey="Moreno, Le" uniqKey="Moreno L">LE Moreno</name></author><author><name sortKey="Rivera, A" uniqKey="Rivera A">A Rivera</name></author><author><name sortKey="Richter, C P" uniqKey="Richter C">C-P Richter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marchese, Mr" uniqKey="Marchese M">MR Marchese</name></author><author><name sortKey="Scorpecci, A" uniqKey="Scorpecci A">A Scorpecci</name></author><author><name sortKey="Cianfrone, F" uniqKey="Cianfrone F">F Cianfrone</name></author><author><name sortKey="Paludetti, G" uniqKey="Paludetti G">G Paludetti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kahrs, La" uniqKey="Kahrs L">LA Kahrs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fuchs, A" uniqKey="Fuchs A">A Fuchs</name></author><author><name sortKey="Schultz, M" uniqKey="Schultz M">M Schultz</name></author><author><name sortKey="Kruger, A" uniqKey="Kruger A">A Krüger</name></author><author><name sortKey="Kundrat, D" uniqKey="Kundrat D">D Kundrat</name></author><author><name sortKey="Diaz Diaz, J" uniqKey="Diaz Diaz J">J Diaz Diaz</name></author><author><name sortKey="Ortmaier, T" uniqKey="Ortmaier T">T Ortmaier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kanawade, R" uniqKey="Kanawade R">R Kanawade</name></author><author><name sortKey="Mehari, F" uniqKey="Mehari F">F Mehari</name></author><author><name sortKey="Knipfer, C" uniqKey="Knipfer C">C Knipfer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kanawade, R" uniqKey="Kanawade R">R Kanawade</name></author><author><name sortKey="Mahari, F" uniqKey="Mahari F">F Mahari</name></author><author><name sortKey="Kl Mpfl, F" uniqKey="Kl Mpfl F">F Klämpfl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="R Tzer Scheibe, A" uniqKey="R Tzer Scheibe A">A Rätzer-Scheibe</name></author><author><name sortKey="Klasing, M" uniqKey="Klasing M">M Klasing</name></author><author><name sortKey="Werner, M" uniqKey="Werner M">M Werner</name></author><author><name sortKey="Ivanenko, M" uniqKey="Ivanenko M">M Ivanenko</name></author><author><name sortKey="Hering, P" uniqKey="Hering P">P Hering</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Steigerwald, H" uniqKey="Steigerwald H">H Steigerwald</name></author><author><name sortKey="Werner, M" uniqKey="Werner M">M Werner</name></author><author><name sortKey="Klasing, M" uniqKey="Klasing M">M Klasing</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leinung, M" uniqKey="Leinung M">M Leinung</name></author><author><name sortKey="Hagner, D" uniqKey="Hagner D">D Hagner</name></author><author><name sortKey="Lenarz, T" uniqKey="Lenarz T">T Lenarz</name></author><author><name sortKey="Schwab, B" uniqKey="Schwab B">B Schwab</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rupprecht, S" uniqKey="Rupprecht S">S Rupprecht</name></author><author><name sortKey="Tangermann, K" uniqKey="Tangermann K">K Tangermann</name></author><author><name sortKey="Kessler, P" uniqKey="Kessler P">P Kessler</name></author><author><name sortKey="Neukam, Fw" uniqKey="Neukam F">FW Neukam</name></author><author><name sortKey="Wiltfang, J" uniqKey="Wiltfang J">J Wiltfang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rupprecht, S" uniqKey="Rupprecht S">S Rupprecht</name></author><author><name sortKey="Tangermann Gerk, K" uniqKey="Tangermann Gerk K">K Tangermann-Gerk</name></author><author><name sortKey="Wiltfang, J" uniqKey="Wiltfang J">J Wiltfang</name></author><author><name sortKey="Neukam, Fw" uniqKey="Neukam F">FW Neukam</name></author><author><name sortKey="Schlegel, A" uniqKey="Schlegel A">A Schlegel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kahrs, La" uniqKey="Kahrs L">LA Kahrs</name></author><author><name sortKey="Raczkowsky, J" uniqKey="Raczkowsky J">J Raczkowsky</name></author><author><name sortKey="Werner, M" uniqKey="Werner M">M Werner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kahrs, La" uniqKey="Kahrs L">LA Kahrs</name></author><author><name sortKey="Werner, M" uniqKey="Werner M">M Werner</name></author><author><name sortKey="Knapp, Fb" uniqKey="Knapp F">FB Knapp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zam, A" uniqKey="Zam A">A Zam</name></author><author><name sortKey="Stelzle, F" uniqKey="Stelzle F">F Stelzle</name></author><author><name sortKey="Nkenke, E" uniqKey="Nkenke E">E Nkenke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stelzle, F" uniqKey="Stelzle F">F Stelzle</name></author><author><name sortKey="Adler, W" uniqKey="Adler W">W Adler</name></author><author><name sortKey="Zam, A" uniqKey="Zam A">A Zam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klenzner, T" uniqKey="Klenzner T">T Klenzner</name></author><author><name sortKey="Knapp, Fb" uniqKey="Knapp F">FB Knapp</name></author><author><name sortKey="Schipper, J" uniqKey="Schipper J">J Schipper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Diaz Diaz, J" uniqKey="Diaz Diaz J">J Diaz Diaz</name></author><author><name sortKey="Kundrat, D" uniqKey="Kundrat D">D Kundrat</name></author><author><name sortKey="Goh, K F" uniqKey="Goh K">K-F Goh</name></author><author><name sortKey="Majdani, O" uniqKey="Majdani O">O Majdani</name></author><author><name sortKey="Ortmaier, T" uniqKey="Ortmaier T">T Ortmaier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leung, By" uniqKey="Leung B">BY Leung</name></author><author><name sortKey="Webster, Pj" uniqKey="Webster P">PJ Webster</name></author><author><name sortKey="Fraser, Jm" uniqKey="Fraser J">JM Fraser</name></author><author><name sortKey="Yang, Vx" uniqKey="Yang V">VX Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fujimoto, J" uniqKey="Fujimoto J">J Fujimoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drexler, W" uniqKey="Drexler W">W Drexler</name></author><author><name sortKey="Fujimoto, Jg" uniqKey="Fujimoto J">JG Fujimoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huber, R" uniqKey="Huber R">R Huber</name></author><author><name sortKey="Wojtkowski, M" uniqKey="Wojtkowski M">M Wojtkowski</name></author><author><name sortKey="Fujimoto, Jg" uniqKey="Fujimoto J">JG Fujimoto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Pfeiffer, T" uniqKey="Pfeiffer T">T Pfeiffer</name></author><author><name sortKey="Wieser, W" uniqKey="Wieser W">W Wieser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Girard, Mja" uniqKey="Girard M">MJA Girard</name></author><author><name sortKey="Strouthidis, Ng" uniqKey="Strouthidis N">NG Strouthidis</name></author><author><name sortKey="Ethier, Cr" uniqKey="Ethier C">CR Ethier</name></author><author><name sortKey="Mari, Jm" uniqKey="Mari J">JM Mari</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Pfeiffer, T" uniqKey="Pfeiffer T">T Pfeiffer</name></author><author><name sortKey="Ding, J" uniqKey="Ding J">J Ding</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003352 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 003352 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= PMC:4177734
|texte= Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:25295253" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a HapticV1
| This area was generated with Dilib version V0.6.23. |  |