Fixation elements on plate intraocular lens : Large positioning holes to improve security of capsular fixation
Identifieur interne : 009083 ( Main/Merge ); précédent : 009082; suivant : 009084Fixation elements on plate intraocular lens : Large positioning holes to improve security of capsular fixation
Auteurs : S. B. Whiteside [États-Unis] ; D. J. Apple [États-Unis] ; QUN PENG [États-Unis] ; R. T. Isaacs [États-Unis] ; A. Guindi [États-Unis] ; R. A. Draughn [États-Unis]Source :
- Ophthalmology : (Rochester, MN) [ 0161-6420 ] ; 1998.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Biomatériau, Lapin.
English descriptors
- KwdEn :
Abstract
Objective: This study aimed to evaluate in rabbit eyes the effects of large positioning holes in one-piece silicone plate-haptic intraocular lenses (lOLs) with respect to security of capsular bag fixation. Mechanical strength of capsular fixation is correlated with the histologic findings of regenerating lens material and fibrous tissue ingrowth through the positioning holes on silicone plate lOLs, comparing capsules implanted with large-hole style plate lOLs to fellow capsules implanted with small-hole style plate lOLs. Design: The study design was a prospective, randomized, experimental study. Participants: A total of 40 fellow capsular bags from 20 New Zealand white rabbits were examined. Capsules implanted with conventional small-hole silicone plate IOLs were used as the control in all pairs of fellow capsules. Intervention: Phacoemulsification and implantation of a silicone plate IOL with small positioning holes in one eye and implantation of a silicone plate IOL with large positioning holes in the fellow eye were measured. All rabbits were killed at 2 months. The force required to extract the lOLs from the capsular bag was measured. All capsular bags underwent histopathologic analysis. Main Outcome Measures: Extraction force measurements and histopathologic examination, comparing capsules implanted with small-hole plate lOLs with fellow capsules implanted with large-hole plate lOLs, were measured. Results: The large-hole style IOL required significantly more force to extract from the capsular bag compared to the conventional small-hole style (P = 0.003). Histologically, proliferating lens epithelial material and fibrous tissue were observed growing through all of the large positioning holes (synechia formation) but not through any of the small positioning holes. Conclusions: Silicone plate lOLs with large positioning holes become affixed more firmly within the capsular bag compared to conventional small-hole plate lOLs. These findings suggest that large holes in silicone plate lOLs allow for superior capsular bag fixation. This should reduce the rates of decentration and dislocation.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 001609
- to stream PascalFrancis, to step Curation: 001511
- to stream PascalFrancis, to step Checkpoint: 001358
Links to Exploration step
Pascal:98-0264311Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Fixation elements on plate intraocular lens : Large positioning holes to improve security of capsular fixation</title><author><name sortKey="Whiteside, S B" sort="Whiteside, S B" uniqKey="Whiteside S" first="S. B." last="Whiteside">S. B. Whiteside</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D. J." last="Apple">D. J. Apple</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Qun Peng" sort="Qun Peng" uniqKey="Qun Peng" last="Qun Peng">QUN PENG</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Isaacs, R T" sort="Isaacs, R T" uniqKey="Isaacs R" first="R. T." last="Isaacs">R. T. Isaacs</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Guindi, A" sort="Guindi, A" uniqKey="Guindi A" first="A." last="Guindi">A. Guindi</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Draughn, R A" sort="Draughn, R A" uniqKey="Draughn R" first="R. A." last="Draughn">R. A. Draughn</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Materials Science, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">98-0264311</idno><date when="1998">1998</date><idno type="stanalyst">PASCAL 98-0264311 INIST</idno><idno type="RBID">Pascal:98-0264311</idno><idno type="wicri:Area/PascalFrancis/Corpus">001609</idno><idno type="wicri:Area/PascalFrancis/Curation">001511</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001358</idno><idno type="wicri:doubleKey">0161-6420:1998:Whiteside S:fixation:elements:on</idno><idno type="wicri:Area/Main/Merge">009083</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Fixation elements on plate intraocular lens : Large positioning holes to improve security of capsular fixation</title><author><name sortKey="Whiteside, S B" sort="Whiteside, S B" uniqKey="Whiteside S" first="S. B." last="Whiteside">S. B. Whiteside</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D. J." last="Apple">D. J. Apple</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Qun Peng" sort="Qun Peng" uniqKey="Qun Peng" last="Qun Peng">QUN PENG</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Isaacs, R T" sort="Isaacs, R T" uniqKey="Isaacs R" first="R. T." last="Isaacs">R. T. Isaacs</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Guindi, A" sort="Guindi, A" uniqKey="Guindi A" first="A." last="Guindi">A. Guindi</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Center for Research on Ocular Therapeutics and Biodevices (formerly Center for Intraocular Lens Research), Storm Eye Institute</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author><author><name sortKey="Draughn, R A" sort="Draughn, R A" uniqKey="Draughn R" first="R. A." last="Draughn">R. A. Draughn</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Materials Science, Medical University of South Carolina</s1><s2>Charleston, South Carolina</s2><s3>USA</s3><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Caroline du Sud</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Ophthalmology : (Rochester, MN)</title><title level="j" type="abbreviated">Ophthalmology : (Rochester MN)</title><idno type="ISSN">0161-6420</idno><imprint><date when="1998">1998</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Ophthalmology : (Rochester, MN)</title><title level="j" type="abbreviated">Ophthalmology : (Rochester MN)</title><idno type="ISSN">0161-6420</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal</term><term>Biomaterial</term><term>Cataract</term><term>Experimental surgery</term><term>Fixation</term><term>Implantation</term><term>Intraocular lens</term><term>Positioning</term><term>Rabbit</term><term>Siloxane polymer</term><term>Technique</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Cataracte</term><term>Lentille intraoculaire</term><term>Implantation</term><term>Positionnement</term><term>Fixation</term><term>Siloxane polymère</term><term>Biomatériau</term><term>Chirurgie expérimentale</term><term>Technique</term><term>Animal</term><term>Lapin</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Biomatériau</term><term>Lapin</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective: This study aimed to evaluate in rabbit eyes the effects of large positioning holes in one-piece silicone plate-haptic intraocular lenses (lOLs) with respect to security of capsular bag fixation. Mechanical strength of capsular fixation is correlated with the histologic findings of regenerating lens material and fibrous tissue ingrowth through the positioning holes on silicone plate lOLs, comparing capsules implanted with large-hole style plate lOLs to fellow capsules implanted with small-hole style plate lOLs. Design: The study design was a prospective, randomized, experimental study. Participants: A total of 40 fellow capsular bags from 20 New Zealand white rabbits were examined. Capsules implanted with conventional small-hole silicone plate IOLs were used as the control in all pairs of fellow capsules. Intervention: Phacoemulsification and implantation of a silicone plate IOL with small positioning holes in one eye and implantation of a silicone plate IOL with large positioning holes in the fellow eye were measured. All rabbits were killed at 2 months. The force required to extract the lOLs from the capsular bag was measured. All capsular bags underwent histopathologic analysis. Main Outcome Measures: Extraction force measurements and histopathologic examination, comparing capsules implanted with small-hole plate lOLs with fellow capsules implanted with large-hole plate lOLs, were measured. Results: The large-hole style IOL required significantly more force to extract from the capsular bag compared to the conventional small-hole style (P = 0.003). Histologically, proliferating lens epithelial material and fibrous tissue were observed growing through all of the large positioning holes (synechia formation) but not through any of the small positioning holes. Conclusions: Silicone plate lOLs with large positioning holes become affixed more firmly within the capsular bag compared to conventional small-hole plate lOLs. These findings suggest that large holes in silicone plate lOLs allow for superior capsular bag fixation. This should reduce the rates of decentration and dislocation.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Caroline du Sud</li></region></list><tree><country name="États-Unis"><region name="Caroline du Sud"><name sortKey="Whiteside, S B" sort="Whiteside, S B" uniqKey="Whiteside S" first="S. B." last="Whiteside">S. B. Whiteside</name></region><name sortKey="Apple, D J" sort="Apple, D J" uniqKey="Apple D" first="D. J." last="Apple">D. J. Apple</name><name sortKey="Draughn, R A" sort="Draughn, R A" uniqKey="Draughn R" first="R. A." last="Draughn">R. A. Draughn</name><name sortKey="Guindi, A" sort="Guindi, A" uniqKey="Guindi A" first="A." last="Guindi">A. Guindi</name><name sortKey="Isaacs, R T" sort="Isaacs, R T" uniqKey="Isaacs R" first="R. T." last="Isaacs">R. T. Isaacs</name><name sortKey="Qun Peng" sort="Qun Peng" uniqKey="Qun Peng" last="Qun Peng">QUN PENG</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009083 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 009083 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Main
|étape= Merge
|type= RBID
|clé= Pascal:98-0264311
|texte= Fixation elements on plate intraocular lens : Large positioning holes to improve security of capsular fixation
}}
| This area was generated with Dilib version V0.6.23. |  |