Intraocular lens changes after short- and long-term exposure to intraocular silicone oil
Identifieur interne : 008F20 ( Main/Merge ); précédent : 008F19; suivant : 008F21Intraocular lens changes after short- and long-term exposure to intraocular silicone oil
Auteurs : Joseph A. Khawly [États-Unis] ; Richard J. Lambert [États-Unis] ; Glenn J. Jaffe [États-Unis]Source :
- Ophthalmology [ 0161-6420 ] ; 1997.
Abstract
Objective Silicone oil frequently is used as a vitreous substitute after complex vitreoretinal procedures. The authors sought to study the effect of short- and long-term exposure to silicone oil on polymethyl methacrylate (PMMA, MC60BM; Alcon, Ft. Worth, TX), silicone (SI-30NB; AMO, Irvine, CA), and soft acrylic (MA60BM; Alcon) intraocular lenses (IOLs).Design An experimental animal study.Intervention Forty-one New Zealand white rabbits underwent lensectomy, vitrectomy, capsulotomy, and placement of one of the three types of IOLs into the ciliary sulcus. All lenses were weighed before implantation and 24 hours after explanation. In the short-term study, an fluid-air exchange was performed followed by the use of silicone oil (1000 centistokes) to coat the posterior lens surface. Immediately thereafter, an air-fluid exchange was performed and the remaining silicone on the posterior lens surface was aspirated or wiped or both for 1 minute using a soft-tipped extrusion cannula for 1 minute. In the long-term study, the posterior segment was filled with 1000 centistokes silicone oil after fluid-air exchange. Animals were observed by slit-lamp biomicroscopy and photographed at 1 week, 1 month, and 3 months after surgery. At 3 months, all animals underwent silicone-fluid exchange, an attempt to manually remove any remaining silicone oil, and lens explanation.Results In the short-term study, no silicone oil remained after manual wiping and/or aspiration in any of the four rabbits implanted with PMMA or acrylic IOLs. In the animals with silicone IOLs, a significant amount of silicone oil remained on the posterior lens surface of all lenses (P < 0.01 for silicone vs. acrylic and silicone vs. PMMA). No statistically significant difference was found when comparing the lens weights in each group before and after implantation. In the long-term study, aqueous droplet formation was found on the posterior lens surface of six of nine PMMA IOLs and ten of ten silicone IOLs at 3 months. No opacities were observed in the group with acrylic IOLs (P < 0.001 for acrylic vs. silicone, P = 0.0018 for acrylic vs. PMMA, and P = 0.047 for PMMA vs. silicone). Adherent silicone oil remained on two of nine PMMA IOLs and on none of ten acrylic IOLs. In contrast, a significant amount of silicone oil remained on the posterior lens surface of ten of ten silicone IOLs (P < 0.001 for silicone vs. acrylic and silicone vs. PMMA). Furthermore, there was a statistically significant increase in lens weights before and after implantation in the silicone IOL group but not in the PMMA or acrylic group (P < 0.01).Conclusions It is extremely difficult or impossible to remove remaining silicone oil from the posterior surface of a silicone IOL after short- or long-term exposure to silicone oil. This oil may interfere with the surgeon’s view of the retina and may diminish the patient’s visual acuity. In contrast, oil is readily removed from the posterior surface of an acrylic IOL. The authors therefore recommend the use of a soft acrylic or PMMA IOL over a silicone IOL when choosing a lens for implantation in patients who may require vitreoretinal procedures with silicone oil tamponade.
Url:
DOI: 10.1016/S0161-6420(98)97025-7
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001390
- to stream Istex, to step Curation: 001390
- to stream Istex, to step Checkpoint: 003903
Links to Exploration step
ISTEX:54B3A343521E54C39B3D7BAD613E9D1187D4B5F9Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Intraocular lens changes after short- and long-term exposure to intraocular silicone oil</title>
<author><name sortKey="Khawly, Joseph A" sort="Khawly, Joseph A" uniqKey="Khawly J" first="Joseph A" last="Khawly">Joseph A. Khawly</name>
</author>
<author><name sortKey="Lambert, Richard J" sort="Lambert, Richard J" uniqKey="Lambert R" first="Richard J" last="Lambert">Richard J. Lambert</name>
</author>
<author><name sortKey="Jaffe, Glenn J" sort="Jaffe, Glenn J" uniqKey="Jaffe G" first="Glenn J" last="Jaffe">Glenn J. Jaffe</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:54B3A343521E54C39B3D7BAD613E9D1187D4B5F9</idno>
<date when="1998" year="1998">1998</date>
<idno type="doi">10.1016/S0161-6420(98)97025-7</idno>
<idno type="url">https://api.istex.fr/document/54B3A343521E54C39B3D7BAD613E9D1187D4B5F9/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001390</idno>
<idno type="wicri:Area/Istex/Curation">001390</idno>
<idno type="wicri:Area/Istex/Checkpoint">003903</idno>
<idno type="wicri:doubleKey">0161-6420:1998:Khawly J:intraocular:lens:changes</idno>
<idno type="wicri:Area/Main/Merge">008F20</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Intraocular lens changes after short- and long-term exposure to intraocular silicone oil</title>
<author><name sortKey="Khawly, Joseph A" sort="Khawly, Joseph A" uniqKey="Khawly J" first="Joseph A" last="Khawly">Joseph A. Khawly</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Duke University Eye Center, Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
<affiliation><wicri:noCountry code="subField">1995–1996.</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lambert, Richard J" sort="Lambert, Richard J" uniqKey="Lambert R" first="Richard J" last="Lambert">Richard J. Lambert</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Alcon Laboratories, Ft. Worth, Texas</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
<affiliation><wicri:noCountry code="subField">Inc</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Jaffe, Glenn J" sort="Jaffe, Glenn J" uniqKey="Jaffe G" first="Glenn J" last="Jaffe">Glenn J. Jaffe</name>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
<wicri:cityArea>Reprint requests to Glenn J. Jaffe, MD, P.O. Box 3802, Duke University Eye Center, Durham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Duke University Eye Center, Durham, North Carolina</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
<affiliation><wicri:noCountry code="no comma">1 Dr. Jaffe is a Lew R. Wassermen Merit Award recipient from Research to Prevent Blindness.</wicri:noCountry>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Ophthalmology</title>
<title level="j" type="abbrev">OPHTHA</title>
<idno type="ISSN">0161-6420</idno>
<imprint><publisher>ELSEVIER</publisher>
<date type="published" when="1997">1997</date>
<biblScope unit="volume">105</biblScope>
<biblScope unit="issue">7</biblScope>
<biblScope unit="page" from="1227">1227</biblScope>
<biblScope unit="page" to="1233">1233</biblScope>
</imprint>
<idno type="ISSN">0161-6420</idno>
</series>
<idno type="istex">54B3A343521E54C39B3D7BAD613E9D1187D4B5F9</idno>
<idno type="DOI">10.1016/S0161-6420(98)97025-7</idno>
<idno type="PII">S0161-6420(98)97025-7</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0161-6420</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Objective Silicone oil frequently is used as a vitreous substitute after complex vitreoretinal procedures. The authors sought to study the effect of short- and long-term exposure to silicone oil on polymethyl methacrylate (PMMA, MC60BM; Alcon, Ft. Worth, TX), silicone (SI-30NB; AMO, Irvine, CA), and soft acrylic (MA60BM; Alcon) intraocular lenses (IOLs).Design An experimental animal study.Intervention Forty-one New Zealand white rabbits underwent lensectomy, vitrectomy, capsulotomy, and placement of one of the three types of IOLs into the ciliary sulcus. All lenses were weighed before implantation and 24 hours after explanation. In the short-term study, an fluid-air exchange was performed followed by the use of silicone oil (1000 centistokes) to coat the posterior lens surface. Immediately thereafter, an air-fluid exchange was performed and the remaining silicone on the posterior lens surface was aspirated or wiped or both for 1 minute using a soft-tipped extrusion cannula for 1 minute. In the long-term study, the posterior segment was filled with 1000 centistokes silicone oil after fluid-air exchange. Animals were observed by slit-lamp biomicroscopy and photographed at 1 week, 1 month, and 3 months after surgery. At 3 months, all animals underwent silicone-fluid exchange, an attempt to manually remove any remaining silicone oil, and lens explanation.Results In the short-term study, no silicone oil remained after manual wiping and/or aspiration in any of the four rabbits implanted with PMMA or acrylic IOLs. In the animals with silicone IOLs, a significant amount of silicone oil remained on the posterior lens surface of all lenses (P < 0.01 for silicone vs. acrylic and silicone vs. PMMA). No statistically significant difference was found when comparing the lens weights in each group before and after implantation. In the long-term study, aqueous droplet formation was found on the posterior lens surface of six of nine PMMA IOLs and ten of ten silicone IOLs at 3 months. No opacities were observed in the group with acrylic IOLs (P < 0.001 for acrylic vs. silicone, P = 0.0018 for acrylic vs. PMMA, and P = 0.047 for PMMA vs. silicone). Adherent silicone oil remained on two of nine PMMA IOLs and on none of ten acrylic IOLs. In contrast, a significant amount of silicone oil remained on the posterior lens surface of ten of ten silicone IOLs (P < 0.001 for silicone vs. acrylic and silicone vs. PMMA). Furthermore, there was a statistically significant increase in lens weights before and after implantation in the silicone IOL group but not in the PMMA or acrylic group (P < 0.01).Conclusions It is extremely difficult or impossible to remove remaining silicone oil from the posterior surface of a silicone IOL after short- or long-term exposure to silicone oil. This oil may interfere with the surgeon’s view of the retina and may diminish the patient’s visual acuity. In contrast, oil is readily removed from the posterior surface of an acrylic IOL. The authors therefore recommend the use of a soft acrylic or PMMA IOL over a silicone IOL when choosing a lens for implantation in patients who may require vitreoretinal procedures with silicone oil tamponade.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 008F20 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 008F20 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Main |étape= Merge |type= RBID |clé= ISTEX:54B3A343521E54C39B3D7BAD613E9D1187D4B5F9 |texte= Intraocular lens changes after short- and long-term exposure to intraocular silicone oil }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |