Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification
Identifieur interne : 008115 ( Main/Merge ); précédent : 008114; suivant : 008116Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification
Auteurs : Jagat Ram [Inde] ; Suresh K. Pandey [États-Unis] ; David J. Apple [États-Unis] ; Liliana Werner [États-Unis] ; Gagandeep S. Brar [Inde] ; Ramandeep Singh [Inde] ; Kulbhushan P. Chaudhary [Inde] ; Amod Gupta [Inde]Source :
- Journal of cataract and refractive surgery [ 0886-3350 ] ; 2001.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Biomatériau, Homme.
English descriptors
- KwdEn :
Abstract
Purpose: To compare the incidence of posterior capsule opacification (PCO) after extracapsular cataract extraction (ECCE) and phacoemulsification and to evaluate the role of posterior chamber intraocular lens (PC IOL) haptic fixation and biomaterial/design in reducing the incidence. Setting: Postgraduate Institute of Medical Education and Research, Chandigarh, India; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Methods: This study comprised 278 eyes of 263 patients having ECCE and 318 eyes of 297 patients having phacoemulsification with PC IOL implantation. Posterior capsule opacification leading to a decrease in Snellen visual acuity of 2 or more lines was considered visually significant. The presence of PCO and IOL haptic fixation were evaluated postoperatively using slitlamp biomicroscopy. Haptic position was noted as in-the-bag (B-B), 1 haptic in the bag and 1 in the sulcus (bag-sulcus [B-S]), or both haptics out of the bag (sulcus-sulcus [S-S]). In addition, the rate of visually significant PCO was compared among 3 IOL biomaterials: poly(methyl methacrylate), silicone, and hydrophobic acrylic. Results: Visually significant PCO occurred in 42.45% of eyes having ECCE and 19.18% of eyes having phacoemulsification (P <.001, chi-square test) after a mean follow-up of 2.4 years ± 0.7 (SD), In both groups, visually significant PCO was significantly less in eyes with B-B fixation than in those with B-S or S-S fixation (P <.001). The rate of visually significant PCO in all eyes in the phacoemulsification group with B-B fixation was low (11.90%) and was significantly lower in eyes with a hydrophobic acrylic IOL (2.22%; P <.05, chi-square test). Conclusions: In-the-bag PC IOL fixation is required to consistently reduce the incidence of PCO. Thorough removal of lens substance, including hydrodissection-assisted cortical cleanup, and in-the-bag PC IOL fixation seem to be the most important factors in reducing PCO, regardless of surgical procedure or IOL type used. Intraocular lens biomaterial and design also help prevent PCO.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 001352
- to stream PascalFrancis, to step Curation: 000160
- to stream PascalFrancis, to step Checkpoint: 001138
Links to Exploration step
Pascal:01-0470941Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification</title>
<author><name sortKey="Ram, Jagat" sort="Ram, Jagat" uniqKey="Ram J" first="Jagat" last="Ram">Jagat Ram</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Chandigarh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K." last="Pandey">Suresh K. Pandey</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Brar, Gagandeep S" sort="Brar, Gagandeep S" uniqKey="Brar G" first="Gagandeep S." last="Brar">Gagandeep S. Brar</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Chandigarh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Singh, Ramandeep" sort="Singh, Ramandeep" uniqKey="Singh R" first="Ramandeep" last="Singh">Ramandeep Singh</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Chandigarh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chaudhary, Kulbhushan P" sort="Chaudhary, Kulbhushan P" uniqKey="Chaudhary K" first="Kulbhushan P." last="Chaudhary">Kulbhushan P. Chaudhary</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Indira Gandbi Medical College Shimla</s1>
<s2>Shimla</s2>
<s3>IND</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Indira Gandbi Medical College Shimla</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gupta, Amod" sort="Gupta, Amod" uniqKey="Gupta A" first="Amod" last="Gupta">Amod Gupta</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Chandigarh</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">01-0470941</idno>
<date when="2001">2001</date>
<idno type="stanalyst">PASCAL 01-0470941 INIST</idno>
<idno type="RBID">Pascal:01-0470941</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001352</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000160</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001138</idno>
<idno type="wicri:doubleKey">0886-3350:2001:Ram J:effect:of:in</idno>
<idno type="wicri:Area/Main/Merge">008115</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification</title>
<author><name sortKey="Ram, Jagat" sort="Ram, Jagat" uniqKey="Ram J" first="Jagat" last="Ram">Jagat Ram</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Chandigarh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K." last="Pandey">Suresh K. Pandey</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>The Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Caroline du Sud</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Brar, Gagandeep S" sort="Brar, Gagandeep S" uniqKey="Brar G" first="Gagandeep S." last="Brar">Gagandeep S. Brar</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Chandigarh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Singh, Ramandeep" sort="Singh, Ramandeep" uniqKey="Singh R" first="Ramandeep" last="Singh">Ramandeep Singh</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Chandigarh</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chaudhary, Kulbhushan P" sort="Chaudhary, Kulbhushan P" uniqKey="Chaudhary K" first="Kulbhushan P." last="Chaudhary">Kulbhushan P. Chaudhary</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Indira Gandbi Medical College Shimla</s1>
<s2>Shimla</s2>
<s3>IND</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Indira Gandbi Medical College Shimla</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gupta, Amod" sort="Gupta, Amod" uniqKey="Gupta A" first="Amod" last="Gupta">Amod Gupta</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Ophthalmology, Postgraduate Institute of Medical Education and Research</s1>
<s2>Chandigarh</s2>
<s3>IND</s3>
<sZ>1 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Inde</country>
<wicri:noRegion>Chandigarh</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of cataract and refractive surgery</title>
<title level="j" type="abbreviated">J. cataract refractive surg.</title>
<idno type="ISSN">0886-3350</idno>
<imprint><date when="2001">2001</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of cataract and refractive surgery</title>
<title level="j" type="abbreviated">J. cataract refractive surg.</title>
<idno type="ISSN">0886-3350</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomaterial</term>
<term>Capsule</term>
<term>Cataract</term>
<term>Comparative study</term>
<term>Extracapsular</term>
<term>Extraction</term>
<term>Eye</term>
<term>Fixation</term>
<term>Human</term>
<term>Incidence</term>
<term>Lens</term>
<term>Opacification</term>
<term>Phacoemulsification</term>
<term>Posterior</term>
<term>Prevention</term>
<term>Technique</term>
<term>Treatment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Cataracte</term>
<term>Technique</term>
<term>Traitement</term>
<term>Extraction</term>
<term>Cristallin</term>
<term>Extracapsulaire</term>
<term>Phacoémulsification</term>
<term>Etude comparative</term>
<term>Incidence</term>
<term>Opacification</term>
<term>Capsule</term>
<term>Postérieur</term>
<term>Prévention</term>
<term>Fixation</term>
<term>Biomatériau</term>
<term>Oeil</term>
<term>Homme</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Biomatériau</term>
<term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Purpose: To compare the incidence of posterior capsule opacification (PCO) after extracapsular cataract extraction (ECCE) and phacoemulsification and to evaluate the role of posterior chamber intraocular lens (PC IOL) haptic fixation and biomaterial/design in reducing the incidence. Setting: Postgraduate Institute of Medical Education and Research, Chandigarh, India; Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA. Methods: This study comprised 278 eyes of 263 patients having ECCE and 318 eyes of 297 patients having phacoemulsification with PC IOL implantation. Posterior capsule opacification leading to a decrease in Snellen visual acuity of 2 or more lines was considered visually significant. The presence of PCO and IOL haptic fixation were evaluated postoperatively using slitlamp biomicroscopy. Haptic position was noted as in-the-bag (B-B), 1 haptic in the bag and 1 in the sulcus (bag-sulcus [B-S]), or both haptics out of the bag (sulcus-sulcus [S-S]). In addition, the rate of visually significant PCO was compared among 3 IOL biomaterials: poly(methyl methacrylate), silicone, and hydrophobic acrylic. Results: Visually significant PCO occurred in 42.45% of eyes having ECCE and 19.18% of eyes having phacoemulsification (P <.001, chi-square test) after a mean follow-up of 2.4 years ± 0.7 (SD), In both groups, visually significant PCO was significantly less in eyes with B-B fixation than in those with B-S or S-S fixation (P <.001). The rate of visually significant PCO in all eyes in the phacoemulsification group with B-B fixation was low (11.90%) and was significantly lower in eyes with a hydrophobic acrylic IOL (2.22%; P <.05, chi-square test). Conclusions: In-the-bag PC IOL fixation is required to consistently reduce the incidence of PCO. Thorough removal of lens substance, including hydrodissection-assisted cortical cleanup, and in-the-bag PC IOL fixation seem to be the most important factors in reducing PCO, regardless of surgical procedure or IOL type used. Intraocular lens biomaterial and design also help prevent PCO.</div>
</front>
</TEI>
<affiliations><list><country><li>Inde</li>
<li>États-Unis</li>
</country>
<region><li>Caroline du Sud</li>
</region>
</list>
<tree><country name="Inde"><noRegion><name sortKey="Ram, Jagat" sort="Ram, Jagat" uniqKey="Ram J" first="Jagat" last="Ram">Jagat Ram</name>
</noRegion>
<name sortKey="Brar, Gagandeep S" sort="Brar, Gagandeep S" uniqKey="Brar G" first="Gagandeep S." last="Brar">Gagandeep S. Brar</name>
<name sortKey="Chaudhary, Kulbhushan P" sort="Chaudhary, Kulbhushan P" uniqKey="Chaudhary K" first="Kulbhushan P." last="Chaudhary">Kulbhushan P. Chaudhary</name>
<name sortKey="Gupta, Amod" sort="Gupta, Amod" uniqKey="Gupta A" first="Amod" last="Gupta">Amod Gupta</name>
<name sortKey="Singh, Ramandeep" sort="Singh, Ramandeep" uniqKey="Singh R" first="Ramandeep" last="Singh">Ramandeep Singh</name>
</country>
<country name="États-Unis"><region name="Caroline du Sud"><name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K." last="Pandey">Suresh K. Pandey</name>
</region>
<name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name>
<name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 008115 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 008115 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Main |étape= Merge |type= RBID |clé= Pascal:01-0470941 |texte= Effect of in-the-bag intraocular lens fixation on the prevention of posterior capsule opacification }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |