Comparative experiments for in vivo fibroplasia and biological stability of four porous polymers intended for use in the Seoul-type keratoprosthesis
Identifieur interne : 007815 ( Main/Merge ); précédent : 007814; suivant : 007816Comparative experiments for in vivo fibroplasia and biological stability of four porous polymers intended for use in the Seoul-type keratoprosthesis
Auteurs : M K Kim [Corée du Sud] ; J L Lee [Corée du Sud] ; W R Wee [Corée du Sud] ; J H Lee [Corée du Sud]Source :
- British Journal of Ophthalmology [ 0007-1161 ] ; 2002-07.
Abstract
Aims: To evaluate in vivo fibroplasia and biological stability of porous polymers intended for use in the Seoul-type keratoprosthesis (S-KPro). Methods: Four porous polymers (polypropylene, two kinds of polyethylene terephthalate (PE70 and PE50), and polyurethane) were investigated. Discs of polymers were inserted into the corneal stroma of rabbits for a 2 and 5 month period. Corneal oedema and neovascularisation were evaluated. The fibroplasia and collagen deposition were examined under light and transmission electron microscopy. S-KPros, whose skirt was made of four types of polymer, were implanted into the rabbits' eyes. The retention time and complications were evaluated. Results: Neovascularisation and corneal oedema were found in all of the disc inserted eyes, but the corneal oedema subsided within 2 months in most of the eyes. The mean number of fibroblasts increased significantly in polypropylene and PE50 disc inserted eyes compared with polyurethane disc inserted eyes. Plentiful collagen deposition was also found in both polypropylene and PE50 disc inserted eyes. Mean retention time in the polypropylene SK-Pro implanted eyes was longer than that of the other eyes (20.7 weeks). The PE70 skirt induced corneal melting around the prosthesis. Conclusion: Polypropylene encourages fibroblast ingrowth and shows good biological stability when used as a skirt material in S-KPro.
Url:
DOI: 10.1136/bjo.86.7.809
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 003079
- to stream Istex, to step Curation: 003079
- to stream Istex, to step Checkpoint: 002912
Links to Exploration step
ISTEX:1ECB984B58CF36709F8642F2C9E464FFD6524EB0Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Comparative experiments for in vivo fibroplasia and biological stability of four porous polymers intended for use in the Seoul-type keratoprosthesis</title><author><name sortKey="Kim, M K" sort="Kim, M K" uniqKey="Kim M" first="M K" last="Kim">M K Kim</name></author><author><name sortKey="Lee, J L" sort="Lee, J L" uniqKey="Lee J" first="J L" last="Lee">J L Lee</name></author><author><name sortKey="Wee, W R" sort="Wee, W R" uniqKey="Wee W" first="W R" last="Wee">W R Wee</name></author><author><name sortKey="Lee, J H" sort="Lee, J H" uniqKey="Lee J" first="J H" last="Lee">J H Lee</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1ECB984B58CF36709F8642F2C9E464FFD6524EB0</idno><date when="2002" year="2002">2002</date><idno type="doi">10.1136/bjo.86.7.809</idno><idno type="url">https://api.istex.fr/document/1ECB984B58CF36709F8642F2C9E464FFD6524EB0/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">003079</idno><idno type="wicri:Area/Istex/Curation">003079</idno><idno type="wicri:Area/Istex/Checkpoint">002912</idno><idno type="wicri:doubleKey">0007-1161:2002:Kim M:comparative:experiments:for</idno><idno type="wicri:Area/Main/Merge">007815</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Comparative experiments for in vivo fibroplasia and biological stability of four porous polymers intended for use in the Seoul-type keratoprosthesis</title><author><name sortKey="Kim, M K" sort="Kim, M K" uniqKey="Kim M" first="M K" last="Kim">M K Kim</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul Municipal Boramae Hospital, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Lee, J L" sort="Lee, J L" uniqKey="Lee J" first="J L" last="Lee">J L Lee</name><affiliation wicri:level="1"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Chungnam National University Hospital, Taejon</wicri:regionArea><wicri:noRegion>Taejon</wicri:noRegion></affiliation></author><author><name sortKey="Wee, W R" sort="Wee, W R" uniqKey="Wee W" first="W R" last="Wee">W R Wee</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University College of Medicine and the Artificial Eye Center, Seoul National University Hospital Clinical Research Center, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Lee, J H" sort="Lee, J H" uniqKey="Lee J" first="J H" last="Lee">J H Lee</name><affiliation wicri:level="3"><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Ophthalmology, Seoul National University College of Medicine and the Artificial Eye Center, Seoul National University Hospital Clinical Research Center, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">British Journal of Ophthalmology</title><title level="j" type="abbrev">Br J Ophthalmol</title><idno type="ISSN">0007-1161</idno><idno type="eISSN">1468-2079</idno><imprint><publisher>BMJ Publishing Group Ltd.</publisher><pubPlace>BMA House, Tavistock Square, London, WC1H 9JR</pubPlace><date type="published" when="2002-07">2002-07</date><biblScope unit="volume">86</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="809">809</biblScope></imprint><idno type="ISSN">0007-1161</idno></series><idno type="istex">1ECB984B58CF36709F8642F2C9E464FFD6524EB0</idno><idno type="DOI">10.1136/bjo.86.7.809</idno><idno type="href">bjophthalmol-86-809.pdf</idno><idno type="PMID">12084755</idno><idno type="local">0860809</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0007-1161</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Aims: To evaluate in vivo fibroplasia and biological stability of porous polymers intended for use in the Seoul-type keratoprosthesis (S-KPro). Methods: Four porous polymers (polypropylene, two kinds of polyethylene terephthalate (PE70 and PE50), and polyurethane) were investigated. Discs of polymers were inserted into the corneal stroma of rabbits for a 2 and 5 month period. Corneal oedema and neovascularisation were evaluated. The fibroplasia and collagen deposition were examined under light and transmission electron microscopy. S-KPros, whose skirt was made of four types of polymer, were implanted into the rabbits' eyes. The retention time and complications were evaluated. Results: Neovascularisation and corneal oedema were found in all of the disc inserted eyes, but the corneal oedema subsided within 2 months in most of the eyes. The mean number of fibroblasts increased significantly in polypropylene and PE50 disc inserted eyes compared with polyurethane disc inserted eyes. Plentiful collagen deposition was also found in both polypropylene and PE50 disc inserted eyes. Mean retention time in the polypropylene SK-Pro implanted eyes was longer than that of the other eyes (20.7 weeks). The PE70 skirt induced corneal melting around the prosthesis. Conclusion: Polypropylene encourages fibroblast ingrowth and shows good biological stability when used as a skirt material in S-KPro.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 007815 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 007815 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Main
|étape= Merge
|type= RBID
|clé= ISTEX:1ECB984B58CF36709F8642F2C9E464FFD6524EB0
|texte= Comparative experiments for in vivo fibroplasia and biological stability of four porous polymers intended for use in the Seoul-type keratoprosthesis
}}
| This area was generated with Dilib version V0.6.23. |  |