Opacification of two hydrophilic acrylic intraocular lenses 3 months after implantation
Identifieur interne : 007465 ( Main/Merge ); précédent : 007464; suivant : 007466Opacification of two hydrophilic acrylic intraocular lenses 3 months after implantation
Auteurs : Tamer A. Macky [États-Unis, Égypte] ; Liliana Werner [États-Unis] ; Mahmoud M. Soliman [Égypte] ; Suresh K. Pandey [États-Unis] ; Andrea M. Izak [États-Unis] ; David J. Apple [États-Unis]Source :
- Ophthalmic surgery lasers & imaging
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- Pascal (Inist)
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- topic : Homme.
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Abstract
▪ BACKGROUND AND OBJECTIVE: To report clinical, pathologic, histochemical, ultrastructural, and spectrographic analyses of explanted hydrophilic acrylic intraocular lenses (IOLs) obtained from two patients who had early visual disturbances caused by postoperative opacification of the lens optic. ▪ MATERIALS AND METHODS: Two hydrophilic IOLs were explanted from patients with decreased visual acuity. The patients became symptomatic 3 months after uneventful phacoemulsification and lens implantation. IOL optic opacification was associated with a fine granularity within the substance of the lens optic. The IOLs were examined by gross and light microscopy. Full-thickness cut sections of the optics were stained with 1% alizarin red (a special stain for calcium). Some sections were submitted for scanning electron microscopy and energy dispersive x-ray spectroscopy. ▪ RESULTS: Microscopic analyses revealed the presence of multiple fine, granular deposits of variable sizes within the optics of the lenses distributed in a line parallel to the anterior and posterior curvatures of the optic, with a clear zone just beneath the optics' surface. Extension of the opacification into the haptics of the IOLs could also be observed. The deposits stained positive with alizarin red. Energy dispersive x-ray spectroscopy of the internal substance of the IOLs also demonstrated the presence of calcium within the deposits. ▪ CONCLUSIONS: This is the first clinicopathologic report of optic and haptic opacification occurring with this hydrophilic acrylic IOL model only 3 months postoperatively. Further studies on other similar cases with this lens should be done to determine the incidence and possible mechanisms of this phenomenon.
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acrylic polymer</term>
<term>Case study</term>
<term>Complication</term>
<term>Human</term>
<term>Hydrophilic compound</term>
<term>Iatrogenic</term>
<term>Intraocular lens</term>
<term>Lens</term>
<term>Opacification</term>
<term>Phacoemulsification</term>
<term>Postoperative</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Lentille intraoculaire</term>
<term>Composé hydrophile</term>
<term>Acrylique dérivé polymère</term>
<term>Opacification</term>
<term>Complication</term>
<term>Iatrogène</term>
<term>Postopératoire</term>
<term>Homme</term>
<term>Etude cas</term>
<term>Phacoémulsification</term>
<term>Cristallin</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
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<front><div type="abstract" xml:lang="en">▪ BACKGROUND AND OBJECTIVE: To report clinical, pathologic, histochemical, ultrastructural, and spectrographic analyses of explanted hydrophilic acrylic intraocular lenses (IOLs) obtained from two patients who had early visual disturbances caused by postoperative opacification of the lens optic. ▪ MATERIALS AND METHODS: Two hydrophilic IOLs were explanted from patients with decreased visual acuity. The patients became symptomatic 3 months after uneventful phacoemulsification and lens implantation. IOL optic opacification was associated with a fine granularity within the substance of the lens optic. The IOLs were examined by gross and light microscopy. Full-thickness cut sections of the optics were stained with 1% alizarin red (a special stain for calcium). Some sections were submitted for scanning electron microscopy and energy dispersive x-ray spectroscopy. ▪ RESULTS: Microscopic analyses revealed the presence of multiple fine, granular deposits of variable sizes within the optics of the lenses distributed in a line parallel to the anterior and posterior curvatures of the optic, with a clear zone just beneath the optics' surface. Extension of the opacification into the haptics of the IOLs could also be observed. The deposits stained positive with alizarin red. Energy dispersive x-ray spectroscopy of the internal substance of the IOLs also demonstrated the presence of calcium within the deposits. ▪ CONCLUSIONS: This is the first clinicopathologic report of optic and haptic opacification occurring with this hydrophilic acrylic IOL model only 3 months postoperatively. Further studies on other similar cases with this lens should be done to determine the incidence and possible mechanisms of this phenomenon.</div>
</front>
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<affiliations><list><country><li>Égypte</li>
<li>États-Unis</li>
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<region><li>Utah</li>
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<name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name>
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<name sortKey="Pandey, Suresh K" sort="Pandey, Suresh K" uniqKey="Pandey S" first="Suresh K." last="Pandey">Suresh K. Pandey</name>
<name sortKey="Werner, Liliana" sort="Werner, Liliana" uniqKey="Werner L" first="Liliana" last="Werner">Liliana Werner</name>
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<country name="Égypte"><noRegion><name sortKey="Macky, Tamer A" sort="Macky, Tamer A" uniqKey="Macky T" first="Tamer A." last="Macky">Tamer A. Macky</name>
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<name sortKey="Soliman, Mahmoud M" sort="Soliman, Mahmoud M" uniqKey="Soliman M" first="Mahmoud M." last="Soliman">Mahmoud M. Soliman</name>
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