High-Resolution Mechanical Imaging of Glioblastoma by Multifrequency Magnetic Resonance Elastography
Identifieur interne : 001152 ( Main/Merge ); précédent : 001151; suivant : 001153High-Resolution Mechanical Imaging of Glioblastoma by Multifrequency Magnetic Resonance Elastography
Auteurs : Kaspar-Josche Streitberger [Allemagne] ; Martin Reiss-Zimmermann [Allemagne] ; Florian Baptist Freimann [Allemagne] ; Simon Bayerl [Allemagne] ; Jing Guo [Allemagne] ; Felix Arlt [Allemagne] ; Jens Wuerfel [Allemagne] ; Jürgen Braun [Allemagne] ; Karl-Titus Hoffmann [Allemagne] ; Ingolf Sack [Allemagne]Source :
- PLoS ONE [ 1932-6203 ] ; 2014.
Abstract
To generate high-resolution maps of the viscoelastic properties of human brain parenchyma for presurgical quantitative assessment in glioblastoma (GB).
Twenty-two GB patients underwent routine presurgical work-up supplemented by additional multifrequency magnetic resonance elastography. Two three-dimensional viscoelastic parameter maps, magnitude
Mechanical brain maps confirmed that GB are composed of stiff and soft compartments, resulting in high intratumor heterogeneity. GB could be easily differentiated from healthy reference tissue by their reduced viscous behavior quantified by φ (0.37±0.08 vs. 0.58±0.07).
GB are generally less viscous and softer than healthy brain parenchyma. Unrelated to the morphology-based contrast of standard magnetic resonance imaging, elastography provides an entirely new neuroradiological marker and contrast related to the biomechanical properties of tumors.
Url:
DOI: 10.1371/journal.pone.0110588
PubMed: 25338072
PubMed Central: 4206430
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Universitätsmedizin Berlin, Berlin, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25338072</idno><idno type="pmc">4206430</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206430</idno><idno type="RBID">PMC:4206430</idno><idno type="doi">10.1371/journal.pone.0110588</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000352</idno><idno type="wicri:Area/Pmc/Curation">000352</idno><idno type="wicri:Area/Pmc/Checkpoint">000C05</idno><idno type="wicri:Area/Ncbi/Merge">003389</idno><idno type="wicri:Area/Ncbi/Curation">003389</idno><idno type="wicri:Area/Ncbi/Checkpoint">003389</idno><idno type="wicri:Area/Main/Merge">001152</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">High-Resolution Mechanical Imaging of Glioblastoma by Multifrequency Magnetic Resonance Elastography</title><author><name sortKey="Streitberger, Kaspar Josche" sort="Streitberger, Kaspar Josche" uniqKey="Streitberger K" first="Kaspar-Josche" last="Streitberger">Kaspar-Josche Streitberger</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Reiss Zimmermann, Martin" sort="Reiss Zimmermann, Martin" uniqKey="Reiss Zimmermann M" first="Martin" last="Reiss-Zimmermann">Martin Reiss-Zimmermann</name><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Department of Neuroradiology, Universitätsmedizin Leipzig, Leipzig, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neuroradiology, Universitätsmedizin Leipzig, Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Freimann, Florian Baptist" sort="Freimann, Florian Baptist" uniqKey="Freimann F" first="Florian Baptist" last="Freimann">Florian Baptist Freimann</name><affiliation wicri:level="3"><nlm:aff id="aff3"><addr-line>Department of Neurosurgery, Universitätsmedizin Göttingen, Göttingen, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurosurgery, Universitätsmedizin Göttingen, Göttingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation></author><author><name sortKey="Bayerl, Simon" sort="Bayerl, Simon" uniqKey="Bayerl S" first="Simon" last="Bayerl">Simon Bayerl</name><affiliation wicri:level="3"><nlm:aff id="aff4"><addr-line>Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurosurgery, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Guo, Jing" sort="Guo, Jing" uniqKey="Guo J" first="Jing" last="Guo">Jing Guo</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Arlt, Felix" sort="Arlt, Felix" uniqKey="Arlt F" first="Felix" last="Arlt">Felix Arlt</name><affiliation wicri:level="3"><nlm:aff id="aff5"><addr-line>Department of Neurosurgery, Universitätsmedizin Leipzig, Leipzig, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurosurgery, Universitätsmedizin Leipzig, Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Wuerfel, Jens" sort="Wuerfel, Jens" uniqKey="Wuerfel J" first="Jens" last="Wuerfel">Jens Wuerfel</name><affiliation wicri:level="3"><nlm:aff id="aff6"><addr-line>Institute of Neuroradiology, Universitätsmedizin Göttingen, Göttingen, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Neuroradiology, Universitätsmedizin Göttingen, Göttingen</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Göttingen</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="aff7"><addr-line>NeuroCure, Charité - Universitätsmedizin Berlin, Berlin, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>NeuroCure, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Braun, Jurgen" sort="Braun, Jurgen" uniqKey="Braun J" first="Jürgen" last="Braun">Jürgen Braun</name><affiliation wicri:level="3"><nlm:aff id="aff8"><addr-line>Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Hoffmann, Karl Titus" sort="Hoffmann, Karl Titus" uniqKey="Hoffmann K" first="Karl-Titus" last="Hoffmann">Karl-Titus Hoffmann</name><affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Department of Neuroradiology, Universitätsmedizin Leipzig, Leipzig, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neuroradiology, Universitätsmedizin Leipzig, Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Sack, Ingolf" sort="Sack, Ingolf" uniqKey="Sack I" first="Ingolf" last="Sack">Ingolf Sack</name><affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany</addr-line></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objective</title><p>To generate high-resolution maps of the viscoelastic properties of human brain parenchyma for presurgical quantitative assessment in glioblastoma (GB).</p></sec><sec><title>Methods</title><p>Twenty-two GB patients underwent routine presurgical work-up supplemented by additional multifrequency magnetic resonance elastography. Two three-dimensional viscoelastic parameter maps, magnitude <italic>|G*|</italic>, and phase angle <italic>φ</italic> of the complex shear modulus were reconstructed by inversion of full wave field data in 2-mm isotropic resolution at seven harmonic drive frequencies ranging from 30 to 60 Hz.</p></sec><sec><title>Results</title><p>Mechanical brain maps confirmed that GB are composed of stiff and soft compartments, resulting in high intratumor heterogeneity. GB could be easily differentiated from healthy reference tissue by their reduced viscous behavior quantified by φ (0.37±0.08 vs. 0.58±0.07). <italic>|G*|</italic>, which in solids more relates to the material's stiffness, was significantly reduced in GB with a mean value of 1.32±0.26 kPa compared to 1.54±0.27 kPa in healthy tissue (P = 0.001). However, some GB (5 of 22) showed increased stiffness.</p></sec><sec><title>Conclusion</title><p>GB are generally less viscous and softer than healthy brain parenchyma. Unrelated to the morphology-based contrast of standard magnetic resonance imaging, elastography provides an entirely new neuroradiological marker and contrast related to the biomechanical properties of tumors.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Furnari, Fb" uniqKey="Furnari F">FB Furnari</name></author><author><name sortKey="Fenton, T" uniqKey="Fenton T">T Fenton</name></author><author><name sortKey="Bachoo, Rm" uniqKey="Bachoo R">RM Bachoo</name></author><author><name sortKey="Mukasa, A" uniqKey="Mukasa A">A Mukasa</name></author><author><name sortKey="Stommel, Jm" uniqKey="Stommel J">JM Stommel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stupp, R" uniqKey="Stupp R">R Stupp</name></author><author><name sortKey="Mason, Wp" uniqKey="Mason W">WP Mason</name></author><author><name sortKey="Van Den Bent, Mj" uniqKey="Van Den Bent M">MJ van den Bent</name></author><author><name sortKey="Weller, M" uniqKey="Weller M">M Weller</name></author><author><name sortKey="Fisher, B" uniqKey="Fisher B">B Fisher</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Davis, Fg" uniqKey="Davis F">FG Davis</name></author><author><name sortKey="Kupelian, V" uniqKey="Kupelian V">V Kupelian</name></author><author><name sortKey="Freels, S" uniqKey="Freels S">S Freels</name></author><author><name sortKey="Mccarthy, B" uniqKey="Mccarthy B">B McCarthy</name></author><author><name sortKey="Surawicz, T" uniqKey="Surawicz T">T Surawicz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dolecek, Ta" uniqKey="Dolecek T">TA Dolecek</name></author><author><name sortKey="Propp, Jm" uniqKey="Propp J">JM Propp</name></author><author><name sortKey="Stroup, Ne" uniqKey="Stroup N">NE Stroup</name></author><author><name sortKey="Kruchko, C" uniqKey="Kruchko C">C Kruchko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Porter, Kr" uniqKey="Porter K">KR Porter</name></author><author><name sortKey="Mccarthy, Bj" uniqKey="Mccarthy B">BJ McCarthy</name></author><author><name sortKey="Freels, S" uniqKey="Freels S">S Freels</name></author><author><name sortKey="Kim, Y" uniqKey="Kim Y">Y Kim</name></author><author><name sortKey="Davis, Fg" uniqKey="Davis F">FG Davis</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Louis, Dn" uniqKey="Louis D">DN Louis</name></author><author><name sortKey="Ohgaki, H" uniqKey="Ohgaki H">H Ohgaki</name></author><author><name sortKey="Wiestler, Od" uniqKey="Wiestler O">OD Wiestler</name></author><author><name sortKey="Cavenee, Wk" uniqKey="Cavenee W">WK Cavenee</name></author><author><name sortKey="Burger, Pc" uniqKey="Burger P">PC Burger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Toh, Ch" uniqKey="Toh C">CH Toh</name></author><author><name sortKey="Wei, Kc" uniqKey="Wei K">KC Wei</name></author><author><name sortKey="Ng, Sh" uniqKey="Ng S">SH Ng</name></author><author><name sortKey="Wan, Yl" uniqKey="Wan Y">YL Wan</name></author><author><name sortKey="Lin, Cp" uniqKey="Lin C">CP Lin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buhring, U" uniqKey="Buhring U">U Buhring</name></author><author><name sortKey="Herrlinger, U" uniqKey="Herrlinger U">U Herrlinger</name></author><author><name sortKey="Krings, T" uniqKey="Krings T">T Krings</name></author><author><name sortKey="Thiex, R" uniqKey="Thiex R">R Thiex</name></author><author><name sortKey="Weller, M" uniqKey="Weller M">M Weller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bernstein, M" uniqKey="Bernstein M">M Bernstein</name></author><author><name sortKey="Parrent, Ag" uniqKey="Parrent A">AG Parrent</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Romano, A" uniqKey="Romano A">A Romano</name></author><author><name sortKey="Scheel, M" uniqKey="Scheel M">M Scheel</name></author><author><name sortKey="Hirsch, S" uniqKey="Hirsch S">S Hirsch</name></author><author><name sortKey="Braun, J" uniqKey="Braun J">J Braun</name></author><author><name sortKey="Sack, I" uniqKey="Sack I">I Sack</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, Cl" uniqKey="Johnson C">CL Johnson</name></author><author><name sortKey="Mcgarry, Md" uniqKey="Mcgarry M">MD McGarry</name></author><author><name sortKey="Gharibans, Aa" uniqKey="Gharibans A">AA Gharibans</name></author><author><name sortKey="Weaver, Jb" uniqKey="Weaver J">JB Weaver</name></author><author><name sortKey="Paulsen, Kd" uniqKey="Paulsen K">KD Paulsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muthupillai, R" uniqKey="Muthupillai R">R Muthupillai</name></author><author><name sortKey="Ehman, Rl" uniqKey="Ehman R">RL Ehman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kruse, Sa" uniqKey="Kruse S">SA Kruse</name></author><author><name sortKey="Rose, Gh" uniqKey="Rose G">GH Rose</name></author><author><name sortKey="Glaser, Kj" uniqKey="Glaser K">KJ Glaser</name></author><author><name sortKey="Manduca, A" uniqKey="Manduca A">A Manduca</name></author><author><name sortKey="Felmlee, Jp" uniqKey="Felmlee J">JP Felmlee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sack, I" uniqKey="Sack I">I Sack</name></author><author><name sortKey="Beierbach, B" uniqKey="Beierbach B">B Beierbach</name></author><author><name sortKey="Hamhaber, U" uniqKey="Hamhaber U">U Hamhaber</name></author><author><name sortKey="Klatt, D" uniqKey="Klatt D">D Klatt</name></author><author><name sortKey="Braun, J" uniqKey="Braun J">J Braun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Green, Ma" uniqKey="Green M">MA Green</name></author><author><name sortKey="Bilston, Le" uniqKey="Bilston L">LE Bilston</name></author><author><name sortKey="Sinkus, R" uniqKey="Sinkus R">R Sinkus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sack, I" uniqKey="Sack I">I Sack</name></author><author><name sortKey="Beierbach, B" uniqKey="Beierbach B">B Beierbach</name></author><author><name sortKey="Wuerfel, J" uniqKey="Wuerfel J">J Wuerfel</name></author><author><name sortKey="Klatt, D" uniqKey="Klatt D">D Klatt</name></author><author><name sortKey="Hamhaber, U" uniqKey="Hamhaber U">U Hamhaber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sack, I" uniqKey="Sack I">I Sack</name></author><author><name sortKey="Streitberger, Kj" uniqKey="Streitberger K">KJ Streitberger</name></author><author><name sortKey="Krefting, D" uniqKey="Krefting D">D Krefting</name></author><author><name sortKey="Paul, F" uniqKey="Paul F">F Paul</name></author><author><name sortKey="Braun, J" uniqKey="Braun J">J Braun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Streitberger, Kj" uniqKey="Streitberger K">KJ Streitberger</name></author><author><name sortKey="Wiener, E" uniqKey="Wiener E">E Wiener</name></author><author><name sortKey="Hoffmann, J" uniqKey="Hoffmann J">J Hoffmann</name></author><author><name sortKey="Freimann, Fb" uniqKey="Freimann F">FB Freimann</name></author><author><name sortKey="Klatt, D" uniqKey="Klatt D">D Klatt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freimann, Fb" uniqKey="Freimann F">FB Freimann</name></author><author><name sortKey="Streitberger, Kj" uniqKey="Streitberger K">KJ Streitberger</name></author><author><name sortKey="Klatt, D" uniqKey="Klatt D">D Klatt</name></author><author><name sortKey="Lin, K" uniqKey="Lin K">K Lin</name></author><author><name sortKey="Mclaughlin, J" uniqKey="Mclaughlin J">J McLaughlin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wuerfel, J" uniqKey="Wuerfel J">J Wuerfel</name></author><author><name sortKey="Paul, F" uniqKey="Paul F">F Paul</name></author><author><name sortKey="Beierbach, B" uniqKey="Beierbach B">B Beierbach</name></author><author><name sortKey="Hamhaber, U" uniqKey="Hamhaber U">U Hamhaber</name></author><author><name sortKey="Klatt, D" uniqKey="Klatt D">D Klatt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murphy, Mc" uniqKey="Murphy M">MC Murphy</name></author><author><name sortKey="Huston, J" uniqKey="Huston J">J Huston</name></author><author><name sortKey="Jack, Cr" uniqKey="Jack C">CR Jack</name></author><author><name sortKey="Glaser, Kj" uniqKey="Glaser K">KJ Glaser</name></author><author><name sortKey="Manduca, A" uniqKey="Manduca A">A Manduca</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Streitberger, Kj" uniqKey="Streitberger K">KJ Streitberger</name></author><author><name sortKey="Sack, I" uniqKey="Sack I">I Sack</name></author><author><name sortKey="Krefting, D" uniqKey="Krefting D">D Krefting</name></author><author><name sortKey="Pfuller, C" uniqKey="Pfuller C">C Pfuller</name></author><author><name sortKey="Braun, J" uniqKey="Braun J">J Braun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lipp, A" uniqKey="Lipp A">A Lipp</name></author><author><name sortKey="Trbojevic, R" uniqKey="Trbojevic R">R Trbojevic</name></author><author><name sortKey="Paul, F" uniqKey="Paul F">F Paul</name></author><author><name sortKey="Fehlner, A" uniqKey="Fehlner A">A Fehlner</name></author><author><name sortKey="Hirsch, S" uniqKey="Hirsch S">S Hirsch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schregel, K" uniqKey="Schregel K">K Schregel</name></author><author><name sortKey="Wuerfel, E" uniqKey="Wuerfel E">E Wuerfel</name></author><author><name sortKey="Garteiser, P" uniqKey="Garteiser P">P Garteiser</name></author><author><name sortKey="Gemeinhardt, I" uniqKey="Gemeinhardt I">I Gemeinhardt</name></author><author><name sortKey="Prozorovski, T" uniqKey="Prozorovski T">T Prozorovski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Riek, K" uniqKey="Riek K">K Riek</name></author><author><name sortKey="Millward, Jm" uniqKey="Millward J">JM Millward</name></author><author><name sortKey="Hamann, I" uniqKey="Hamann I">I Hamann</name></author><author><name sortKey="Mueller, S" uniqKey="Mueller S">S Mueller</name></author><author><name sortKey="Pfueller, Cf" uniqKey="Pfueller C">CF Pfueller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freimann, Fb" uniqKey="Freimann F">FB Freimann</name></author><author><name sortKey="Muller, S" uniqKey="Muller S">S Muller</name></author><author><name sortKey="Streitberger, Kj" uniqKey="Streitberger K">KJ Streitberger</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name></author><author><name sortKey="Rot, S" uniqKey="Rot S">S Rot</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simon, M" uniqKey="Simon M">M Simon</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name></author><author><name sortKey="Papazoglou, S" uniqKey="Papazoglou S">S Papazoglou</name></author><author><name sortKey="Scholand Engler, H" uniqKey="Scholand Engler H">H Scholand-Engler</name></author><author><name sortKey="Erdmann, C" uniqKey="Erdmann C">C Erdmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murphy, Mc" uniqKey="Murphy M">MC Murphy</name></author><author><name sortKey="Huston, J" uniqKey="Huston J">J Huston</name></author><author><name sortKey="Glaser, Kj" uniqKey="Glaser K">KJ Glaser</name></author><author><name sortKey="Manduca, A" uniqKey="Manduca A">A Manduca</name></author><author><name sortKey="Meyer, Fb" uniqKey="Meyer F">FB Meyer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, L" uniqKey="Xu L">L Xu</name></author><author><name sortKey="Lin, Y" uniqKey="Lin Y">Y Lin</name></author><author><name sortKey="Han, Jc" uniqKey="Han J">JC Han</name></author><author><name sortKey="Xi, Zn" uniqKey="Xi Z">ZN Xi</name></author><author><name sortKey="Shen, H" uniqKey="Shen H">H Shen</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hirsch, S" uniqKey="Hirsch S">S Hirsch</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name></author><author><name sortKey="Reiter, R" uniqKey="Reiter R">R Reiter</name></author><author><name sortKey="Papazoglou, S" uniqKey="Papazoglou S">S Papazoglou</name></author><author><name sortKey="Kroencke, T" uniqKey="Kroencke T">T Kroencke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Papazoglou, S" uniqKey="Papazoglou S">S Papazoglou</name></author><author><name sortKey="Hirsch, S" uniqKey="Hirsch S">S Hirsch</name></author><author><name sortKey="Braun, J" uniqKey="Braun J">J Braun</name></author><author><name sortKey="Sack, I" uniqKey="Sack I">I Sack</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baghani, A" uniqKey="Baghani A">A Baghani</name></author><author><name sortKey="Salcudean, S" uniqKey="Salcudean S">S Salcudean</name></author><author><name sortKey="Honarvar, M" uniqKey="Honarvar M">M Honarvar</name></author><author><name sortKey="Sahebjavaher, Rs" uniqKey="Sahebjavaher R">RS Sahebjavaher</name></author><author><name sortKey="Rohling, R" uniqKey="Rohling R">R Rohling</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barnhill, E" uniqKey="Barnhill E">E Barnhill</name></author><author><name sortKey="Kennedy, P" uniqKey="Kennedy P">P Kennedy</name></author><author><name sortKey="Hammer, S" uniqKey="Hammer S">S Hammer</name></author><author><name sortKey="Van Beek, Ej" uniqKey="Van Beek E">EJ van Beek</name></author><author><name sortKey="Brown, C" uniqKey="Brown C">C Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murphy, Mc" uniqKey="Murphy M">MC Murphy</name></author><author><name sortKey="Huston, J" uniqKey="Huston J">J Huston</name></author><author><name sortKey="Jack, Cr" uniqKey="Jack C">CR Jack</name></author><author><name sortKey="Glaser, K" uniqKey="Glaser K">K Glaser</name></author><author><name sortKey="Senjem, Ml" uniqKey="Senjem M">ML Senjem</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name></author><author><name sortKey="Hirsch, S" uniqKey="Hirsch S">S Hirsch</name></author><author><name sortKey="Fehlner, A" uniqKey="Fehlner A">A Fehlner</name></author><author><name sortKey="Papazoglou, S" uniqKey="Papazoglou S">S Papazoglou</name></author><author><name sortKey="Scheel, M" uniqKey="Scheel M">M Scheel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Braun, J" uniqKey="Braun J">J Braun</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name></author><author><name sortKey="Lutzkendorf, R" uniqKey="Lutzkendorf R">R Lützkendorf</name></author><author><name sortKey="Stadler, J" uniqKey="Stadler J">J Stadler</name></author><author><name sortKey="Papazoglou, S" uniqKey="Papazoglou S">S Papazoglou</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Rump, J" uniqKey="Rump J">J Rump</name></author><author><name sortKey="Klatt, D" uniqKey="Klatt D">D Klatt</name></author><author><name sortKey="Braun, J" uniqKey="Braun J">J Braun</name></author><author><name sortKey="Warmuth, C" uniqKey="Warmuth C">C Warmuth</name></author><author><name sortKey="Sack, I" uniqKey="Sack I">I Sack</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Papazoglou, S" uniqKey="Papazoglou S">S Papazoglou</name></author><author><name sortKey="Xu, C" uniqKey="Xu C">C Xu</name></author><author><name sortKey="Hamhaber, U" uniqKey="Hamhaber U">U Hamhaber</name></author><author><name sortKey="Siebert, E" uniqKey="Siebert E">E Siebert</name></author><author><name sortKey="Bohner, G" uniqKey="Bohner G">G Bohner</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Oliphant, Te" uniqKey="Oliphant T">TE Oliphant</name></author><author><name sortKey="Manduca, A" uniqKey="Manduca A">A Manduca</name></author><author><name sortKey="Ehman, Rl" uniqKey="Ehman R">RL Ehman</name></author><author><name sortKey="Greenleaf, Jf" uniqKey="Greenleaf J">JF Greenleaf</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hamhaber, U" uniqKey="Hamhaber U">U Hamhaber</name></author><author><name sortKey="Klatt, D" uniqKey="Klatt D">D Klatt</name></author><author><name sortKey="Papazoglou, S" uniqKey="Papazoglou S">S Papazoglou</name></author><author><name sortKey="Hollmann, M" uniqKey="Hollmann M">M Hollmann</name></author><author><name sortKey="Stadler, J" uniqKey="Stadler J">J Stadler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sack, I" uniqKey="Sack I">I Sack</name></author><author><name sortKey="Joehrens, K" uniqKey="Joehrens K">K Joehrens</name></author><author><name sortKey="Wuerfel, E" uniqKey="Wuerfel E">E Wuerfel</name></author><author><name sortKey="Braun, J" uniqKey="Braun J">J Braun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Basan, M" uniqKey="Basan M">M Basan</name></author><author><name sortKey="Risler, T" uniqKey="Risler T">T Risler</name></author><author><name sortKey="Joanny, Jf" uniqKey="Joanny J">JF Joanny</name></author><author><name sortKey="Sastre Garau, X" uniqKey="Sastre Garau X">X Sastre-Garau</name></author><author><name sortKey="Prost, J" uniqKey="Prost J">J Prost</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garteiser, P" uniqKey="Garteiser P">P Garteiser</name></author><author><name sortKey="Doblas, S" uniqKey="Doblas S">S Doblas</name></author><author><name sortKey="Daire, Jl" uniqKey="Daire J">JL Daire</name></author><author><name sortKey="Wagner, M" uniqKey="Wagner M">M Wagner</name></author><author><name sortKey="Leitao, H" uniqKey="Leitao H">H Leitao</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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