Security of capsular fixation: Smallversus large-hole plate-haptic lenses
Identifieur interne : 008A08 ( Main/Exploration ); précédent : 008A07; suivant : 008A09Security of capsular fixation: Smallversus large-hole plate-haptic lenses
Auteurs : David G. Kent ; Qun Peng ; Robert T. Isaacs ; Stephen B. Whiteside ; Derek L. Barker ; David J. AppleSource :
- Journal of Cataract & Refractive Surgery [ 0886-3350 ] ; 1997.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Biomatériau, Homme.
English descriptors
- KwdEn :
- Animals, Biomaterial, Cell Division, Epithelial Cells (cytology), Female, Fixation, Foreign-Body Migration (prevention & control), Human, Intraocular lens, Lens Capsule, Crystalline (cytology), Lens Capsule, Crystalline (surgery), Lenses, Intraocular, Phacoemulsification (methods), Positioning, Postoperative Complications (prevention & control), Rabbits, Safety, Silicone Elastomers, Siloxane polymer, Technique, Treatment Outcome.
- MESH :
- chemical : Silicone Elastomers.
- cytology : Epithelial Cells, Lens Capsule, Crystalline.
- methods : Phacoemulsification.
- prevention & control : Foreign-Body Migration, Postoperative Complications.
- surgery : Lens Capsule, Crystalline.
- Animals, Cell Division, Female, Lenses, Intraocular, Rabbits, Treatment Outcome.
Abstract
Purpose: To assess the effect of relatively large positioning holes on the security of capsular bag fixation of plate-haptic silicone intraocular lenses (IOLs).Setting: Center for Research on Ocular Therapeutics and Biodevices, Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.Methods: This study tested the hypothesis that larger holes allow ingrowth of lens material, fibrous tissue, or both through them, which helps fixate the lens more firmly in the capsular bag. Five rabbits had bilateral continuous curvilinear capsulorhexis, phacoemulsification, and implantation of a plate-haptic silicone IOL. An IOL with a small, round positioning hole (Staar AA-4203V) was implanted in the right eye in each rabbit, and a large-hole IOL (Staar AA-4203VF) was implanted in the left eye. After 2 months, all rabbits were killed. The force required to extract one haptic from the capsular bag was measured with a digital force meter. All eyes had histopathological analysis.Results: It was slightly more difficult to extract a large-hole IOL from the capsular bag, although this trend was not statistically significant. However, histopathological analysis consistently showed 360 degree synechia formation through the holes, showing that the IOL could be securely fixed in position.Conclusions: Proliferation of lens epithelial cells through a large positioning hole in a plate-haptic silicone IOL may improve the long-term security of capsular bag fixation. This will help reduce the incidence of IOL decentration and dislocation.
Url:
DOI: 10.1016/S0886-3350(97)80116-2
Affiliations:
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Le document en format XML
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Kent</name><affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharleston</wicri:noCountry></affiliation></author><author><name sortKey="Peng, Qun" sort="Peng, Qun" uniqKey="Peng Q" first="Qun" last="Peng">Qun Peng</name><affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharleston</wicri:noCountry></affiliation></author><author><name sortKey="Isaacs, Robert T" sort="Isaacs, Robert T" uniqKey="Isaacs R" first="Robert T." last="Isaacs">Robert T. Isaacs</name><affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharleston</wicri:noCountry></affiliation></author><author><name sortKey="Whiteside, Stephen B" sort="Whiteside, Stephen B" uniqKey="Whiteside S" first="Stephen B." last="Whiteside">Stephen B. Whiteside</name><affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharleston</wicri:noCountry></affiliation></author><author><name sortKey="Barker, Derek L" sort="Barker, Derek L" uniqKey="Barker D" first="Derek L." last="Barker">Derek L. Barker</name><affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharleston</wicri:noCountry></affiliation></author><author><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name><affiliation><wicri:noCountry code="subField">Medical University of South CarolinaCharleston</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Cataract & Refractive Surgery</title><title level="j" type="abbrev">JCRS</title><idno type="ISSN">0886-3350</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1997">1997</date><biblScope unit="volume">23</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="1371">1371</biblScope><biblScope unit="page" to="1375">1375</biblScope></imprint><idno type="ISSN">0886-3350</idno></series><idno type="istex">154AB9BC75B42AB6604B95C4CCC8BBFA785B3272</idno><idno type="DOI">10.1016/S0886-3350(97)80116-2</idno><idno type="PII">S0886-3350(97)80116-2</idno><idno type="ArticleID">80116</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0886-3350</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Biomaterial</term><term>Cell Division</term><term>Epithelial Cells (cytology)</term><term>Female</term><term>Fixation</term><term>Foreign-Body Migration (prevention & control)</term><term>Human</term><term>Intraocular lens</term><term>Lens Capsule, Crystalline (cytology)</term><term>Lens Capsule, Crystalline (surgery)</term><term>Lenses, Intraocular</term><term>Phacoemulsification (methods)</term><term>Positioning</term><term>Postoperative Complications (prevention & control)</term><term>Rabbits</term><term>Safety</term><term>Silicone Elastomers</term><term>Siloxane polymer</term><term>Technique</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Silicone Elastomers</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Epithelial Cells</term><term>Lens Capsule, Crystalline</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Phacoemulsification</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Foreign-Body Migration</term><term>Postoperative Complications</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Lens Capsule, Crystalline</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Division</term><term>Female</term><term>Lenses, Intraocular</term><term>Rabbits</term><term>Treatment Outcome</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Biomatériau</term><term>Fixation</term><term>Homme</term><term>Lentille intraoculaire</term><term>Positionnement</term><term>Siloxane polymère</term><term>Sécurité</term><term>Technique</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Biomatériau</term><term>Homme</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Purpose: To assess the effect of relatively large positioning holes on the security of capsular bag fixation of plate-haptic silicone intraocular lenses (IOLs).Setting: Center for Research on Ocular Therapeutics and Biodevices, Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.Methods: This study tested the hypothesis that larger holes allow ingrowth of lens material, fibrous tissue, or both through them, which helps fixate the lens more firmly in the capsular bag. Five rabbits had bilateral continuous curvilinear capsulorhexis, phacoemulsification, and implantation of a plate-haptic silicone IOL. An IOL with a small, round positioning hole (Staar AA-4203V) was implanted in the right eye in each rabbit, and a large-hole IOL (Staar AA-4203VF) was implanted in the left eye. After 2 months, all rabbits were killed. The force required to extract one haptic from the capsular bag was measured with a digital force meter. All eyes had histopathological analysis.Results: It was slightly more difficult to extract a large-hole IOL from the capsular bag, although this trend was not statistically significant. However, histopathological analysis consistently showed 360 degree synechia formation through the holes, showing that the IOL could be securely fixed in position.Conclusions: Proliferation of lens epithelial cells through a large positioning hole in a plate-haptic silicone IOL may improve the long-term security of capsular bag fixation. This will help reduce the incidence of IOL decentration and dislocation.</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Apple, David J" sort="Apple, David J" uniqKey="Apple D" first="David J." last="Apple">David J. Apple</name><name sortKey="Barker, Derek L" sort="Barker, Derek L" uniqKey="Barker D" first="Derek L." last="Barker">Derek L. Barker</name><name sortKey="Isaacs, Robert T" sort="Isaacs, Robert T" uniqKey="Isaacs R" first="Robert T." last="Isaacs">Robert T. Isaacs</name><name sortKey="Kent, David G" sort="Kent, David G" uniqKey="Kent D" first="David G." last="Kent">David G. Kent</name><name sortKey="Peng, Qun" sort="Peng, Qun" uniqKey="Peng Q" first="Qun" last="Peng">Qun Peng</name><name sortKey="Whiteside, Stephen B" sort="Whiteside, Stephen B" uniqKey="Whiteside S" first="Stephen B." last="Whiteside">Stephen B. Whiteside</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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