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Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound

Identifieur interne : 006567 ( Main/Exploration ); précédent : 006566; suivant : 006568

Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound

Auteurs : Oliver Stachs [Allemagne] ; Hanka Schneider [Allemagne] ; Joachim Stave [Allemagne] ; Rudolf Guthoff [Allemagne]

Source :

Journal of refractive surgery : (1995) [ 1081-597X ] ; 2005.

RBID : Pascal:05-0148130

Descripteurs français

Pascal (Inist)
- Lentille intraoculaire, In vitro, In vivo, Echographie tridimensionnelle, Haute fréquence, Chirurgie, Ophtalmologie.
Wicri :
- topic : Chirurgie.

English descriptors

KwdEn :
- High frequency, In vitro, In vivo, Intraocular lens, Ophthalmology, Surgery, Three-dimensional ultrasound.

Abstract

PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.

Affiliations:

Allemagne

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Le document en format XML

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<front><div type="abstract" xml:lang="en">PURPOSE: To investigate the accommodative performance of new intraocular lenses (IOLs) using the advantages of three-dimensional ultrasound biomicroscopy. METHODS: An in vitro simulation device was designed to study IOL performance using an artificial capsular bag and a stretching device. The haptic region of the Akkom-modative 1CU (HumanOptics AG) and CrystaLens AT-45 (Eyeonics Inc) was visualized in vitro in three dimensions, using an in-house developed three-dimensional ultrasound biomicroscope. The in vitro results were used to describe the in vivo situation in four patients with accommodative implants. RESULTS: The haptic position and angulation in consideration of the accommodation state was distinguished and analyzed. In the simulation model, a maximal angulation change of 4.5° and 4.3° and a maximal forward shift of 0.33 mm and 0.28 mm was observed for the AT-45 and 1CU, respectively. In vivo, a change in haptic angulation <10° and a maximal forward shift of 0.50 mm was observed for the 1CU. These changes correspond to a theoretical approximate value of 0.50 diopters. CONCLUSIONS: The in vitro simulation device examined with three-dimensional ultrasound biomicroscopy provided information on the accommodative performance of these potentially accommodative IOL designs. Using three-dimensional ultrasound biomicroscopy, corresponding changes in haptic angulation during pharmacological-induced accommodation were observed.</div>
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Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound

Potentially accommodating intraocular lenses-an in vitro and in vivo study using three-dimensional high-frequency ultrasound

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri