Image based evaluation of mediastinal constraints for the development of a pulsatile total artificial heart
Identifieur interne : 001B04 ( Main/Exploration ); précédent : 001B03; suivant : 001B05Image based evaluation of mediastinal constraints for the development of a pulsatile total artificial heart
Auteurs : Andreas Johann Fritschi [Allemagne] ; Marco Laumen [Allemagne] ; Sotirios Spiliopoulos [Allemagne] ; Thomas Finocchiaro [Allemagne] ; Christina Egger [Allemagne] ; Thomas Schmitz-Rode [Allemagne] ; Gero Tenderich [Allemagne] ; Reiner Koerfer [Allemagne] ; Ulrich Steinseifer [Allemagne]Source :
- BioMedical Engineering OnLine [ 1475-925X ] ; 2013.
English descriptors
- KwdEn :
- MESH :
- adverse effects : Heart, Artificial.
- methods : Prosthesis Design.
- radiography : Heart Failure.
- surgery : Heart Failure.
- Female, Humans, Image Processing, Computer-Assisted, Male, Mediastinum, User-Computer Interface.
Abstract
Good anatomical compatibility is an important aspect in the development of cardiovascular implants. This work analyzes the interaction of the pump unit of an electrically driven pulsatile Total Artificial Heart (TAH) and the mediastinum. For an adequate compliance, both overall dimensions and alignment of inlets and outlets must be matched.
Cross-sectional medical image data of 27 individuals, including male and female patients suffering from end stage heart failure, was segmented and reconstructed to three dimensional (3D) surface models. Dimensions and orientations of relevant structures were identified and analyzed. The TAH surface model was virtually placed in orthotopic position and aligned with atrioventricular valves and big vessels. Additionally seven conventional cadaver studies were performed to validate different pump chamber designs based on virtual findings. Thereby 3D-coordinates were captured and introduced to the virtual environment to allow quantitative comparison between different individuals.
Spatial parameters varied more in male patients with higher values if heart failure persists. Good correlation of the virtual analysis both to literature data and conventional cadaver studies could be shown. The full data of the 27 individuals as well as the summarized values found in literature are enclosed in the appendix. By superimposing the TAH-volume model to the anatomy, various misalignments were found and the TAH-design was adjusted.
Virtual fitting allows implant design adjustments in realistic anatomy which has not been influenced by thoracotomy. Higher numbers of relevant individuals can be reasonably investigated in the virtual environment and quantitatively correlated. Using this approach, conventional cadaver studies can be significantly reduced but not obviated, due to the unavailable haptic feedback and immobility of potentially compressed structures.
Url:
DOI: 10.1186/1475-925X-12-81
PubMed: 23941400
PubMed Central: 3751639
Affiliations:
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Le document en format XML
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<author><name sortKey="Egger, Christina" sort="Egger, Christina" uniqKey="Egger C" first="Christina" last="Egger">Christina Egger</name>
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<author><name sortKey="Schmitz Rode, Thomas" sort="Schmitz Rode, Thomas" uniqKey="Schmitz Rode T" first="Thomas" last="Schmitz-Rode">Thomas Schmitz-Rode</name>
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<wicri:regionArea>Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Helmholtz Institute, RWTH-Aachen University, Aachen</wicri:regionArea>
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<author><name sortKey="Tenderich, Gero" sort="Tenderich, Gero" uniqKey="Tenderich G" first="Gero" last="Tenderich">Gero Tenderich</name>
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<wicri:noRegion>Duisburg</wicri:noRegion>
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<author><name sortKey="Koerfer, Reiner" sort="Koerfer, Reiner" uniqKey="Koerfer R" first="Reiner" last="Koerfer">Reiner Koerfer</name>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department for the Surgical Therapy of end-stage Heart Failure and Mechanical Circulatory Support, Heart- and Vascular Center Duisburg, Duisburg</wicri:regionArea>
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<author><name sortKey="Steinseifer, Ulrich" sort="Steinseifer, Ulrich" uniqKey="Steinseifer U" first="Ulrich" last="Steinseifer">Ulrich Steinseifer</name>
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<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Helmholtz Institute, RWTH-Aachen University, Aachen</wicri:regionArea>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Female</term>
<term>Heart Failure (radiography)</term>
<term>Heart Failure (surgery)</term>
<term>Heart, Artificial (adverse effects)</term>
<term>Humans</term>
<term>Image Processing, Computer-Assisted</term>
<term>Male</term>
<term>Mediastinum</term>
<term>Prosthesis Design (methods)</term>
<term>User-Computer Interface</term>
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<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Heart, Artificial</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Prosthesis Design</term>
</keywords>
<keywords scheme="MESH" qualifier="radiography" xml:lang="en"><term>Heart Failure</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Heart Failure</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
<term>Image Processing, Computer-Assisted</term>
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Good anatomical compatibility is an important aspect in the development of cardiovascular implants. This work analyzes the interaction of the pump unit of an electrically driven pulsatile Total Artificial Heart (TAH) and the mediastinum. For an adequate compliance, both overall dimensions and alignment of inlets and outlets must be matched.</p>
</sec>
<sec><title>Methods</title>
<p>Cross-sectional medical image data of 27 individuals, including male and female patients suffering from end stage heart failure, was segmented and reconstructed to three dimensional (3D) surface models. Dimensions and orientations of relevant structures were identified and analyzed. The TAH surface model was virtually placed in orthotopic position and aligned with atrioventricular valves and big vessels. Additionally seven conventional cadaver studies were performed to validate different pump chamber designs based on virtual findings. Thereby 3D-coordinates were captured and introduced to the virtual environment to allow quantitative comparison between different individuals.</p>
</sec>
<sec><title>Results</title>
<p>Spatial parameters varied more in male patients with higher values if heart failure persists. Good correlation of the virtual analysis both to literature data and conventional cadaver studies could be shown. The full data of the 27 individuals as well as the summarized values found in literature are enclosed in the appendix. By superimposing the TAH-volume model to the anatomy, various misalignments were found and the TAH-design was adjusted.</p>
</sec>
<sec><title>Conclusions</title>
<p>Virtual fitting allows implant design adjustments in realistic anatomy which has not been influenced by thoracotomy. Higher numbers of relevant individuals can be reasonably investigated in the virtual environment and quantitatively correlated. Using this approach, conventional cadaver studies can be significantly reduced but not obviated, due to the unavailable haptic feedback and immobility of potentially compressed structures.</p>
</sec>
</div>
</front>
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<biblStruct><analytic><author><name sortKey="Copeland, Jg" uniqKey="Copeland J">JG Copeland</name>
</author>
<author><name sortKey="Copeland, H" uniqKey="Copeland H">H Copeland</name>
</author>
<author><name sortKey="Gustafson, M" uniqKey="Gustafson M">M Gustafson</name>
</author>
<author><name sortKey="Mineburg, N" uniqKey="Mineburg N">N Mineburg</name>
</author>
<author><name sortKey="Covington, D" uniqKey="Covington D">D Covington</name>
</author>
<author><name sortKey="Smith, Rg" uniqKey="Smith R">RG Smith</name>
</author>
<author><name sortKey="Friedman, M" uniqKey="Friedman M">M Friedman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Slaughter, Ms" uniqKey="Slaughter M">MS Slaughter</name>
</author>
<author><name sortKey="Myers, Tj" uniqKey="Myers T">TJ Myers</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Finocchiaro, T" uniqKey="Finocchiaro T">T Finocchiaro</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pohlmann, A" uniqKey="Pohlmann A">A Pohlmann</name>
</author>
<author><name sortKey="Lessmann, M" uniqKey="Lessmann M">M Lessmann</name>
</author>
<author><name sortKey="Fritschi, A" uniqKey="Fritschi A">A Fritschi</name>
</author>
<author><name sortKey="Finocchiaro, T" uniqKey="Finocchiaro T">T Finocchiaro</name>
</author>
<author><name sortKey="Steinseifer, U" uniqKey="Steinseifer U">U Steinseifer</name>
</author>
<author><name sortKey="Hameyer, K" uniqKey="Hameyer K">K Hameyer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Komoda, T" uniqKey="Komoda T">T Komoda</name>
</author>
<author><name sortKey="Uyama, C" uniqKey="Uyama C">C Uyama</name>
</author>
<author><name sortKey="Maeta, H" uniqKey="Maeta H">H Maeta</name>
</author>
<author><name sortKey="Ozaki, K" uniqKey="Ozaki K">K Ozaki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Komoda, T" uniqKey="Komoda T">T Komoda</name>
</author>
<author><name sortKey="Uyama, C" uniqKey="Uyama C">C Uyama</name>
</author>
<author><name sortKey="Maeta, H" uniqKey="Maeta H">H Maeta</name>
</author>
<author><name sortKey="Sanou, K" uniqKey="Sanou K">K Sanou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Komoda, T" uniqKey="Komoda T">T Komoda</name>
</author>
<author><name sortKey="Uyama, C" uniqKey="Uyama C">C Uyama</name>
</author>
<author><name sortKey="Maeta, H" uniqKey="Maeta H">H Maeta</name>
</author>
<author><name sortKey="Ozaki, K" uniqKey="Ozaki K">K Ozaki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chatel, D" uniqKey="Chatel D">D Chatel</name>
</author>
<author><name sortKey="Martin Bouyer, Y" uniqKey="Martin Bouyer Y">Y Martin-Bouyer</name>
</author>
<author><name sortKey="Vicaut, E" uniqKey="Vicaut E">E Vicaut</name>
</author>
<author><name sortKey="Bouchoucha, H" uniqKey="Bouchoucha H">H Bouchoucha</name>
</author>
<author><name sortKey="Achard, F" uniqKey="Achard F">F Achard</name>
</author>
<author><name sortKey="Sablayrolles, Jl" uniqKey="Sablayrolles J">JL Sablayrolles</name>
</author>
<author><name sortKey="Carpentier, A" uniqKey="Carpentier A">A Carpentier</name>
</author>
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<biblStruct><analytic><author><name sortKey="Shah, As" uniqKey="Shah A">AS Shah</name>
</author>
<author><name sortKey="Shiono, M" uniqKey="Shiono M">M Shiono</name>
</author>
<author><name sortKey="Jikuya, T" uniqKey="Jikuya T">T Jikuya</name>
</author>
<author><name sortKey="Takatani, S" uniqKey="Takatani S">S Takatani</name>
</author>
<author><name sortKey="Sekela, Me" uniqKey="Sekela M">ME Sekela</name>
</author>
<author><name sortKey="Noon, Gp" uniqKey="Noon G">GP Noon</name>
</author>
<author><name sortKey="Young, Jb" uniqKey="Young J">JB Young</name>
</author>
<author><name sortKey="Nose, Y" uniqKey="Nose Y">Y Nose</name>
</author>
<author><name sortKey="Debakey, Me" uniqKey="Debakey M">ME DeBakey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shiono, M" uniqKey="Shiono M">M Shiono</name>
</author>
<author><name sortKey="Shah, As" uniqKey="Shah A">AS Shah</name>
</author>
<author><name sortKey="Sasaki, T" uniqKey="Sasaki T">T Sasaki</name>
</author>
<author><name sortKey="Takatani, S" uniqKey="Takatani S">S Takatani</name>
</author>
<author><name sortKey="Sekela, Me" uniqKey="Sekela M">ME Sekela</name>
</author>
<author><name sortKey="Noon, Gp" uniqKey="Noon G">GP Noon</name>
</author>
<author><name sortKey="Young, Jb" uniqKey="Young J">JB Young</name>
</author>
<author><name sortKey="Nose, Y" uniqKey="Nose Y">Y Nose</name>
</author>
<author><name sortKey="Debakey, Me" uniqKey="Debakey M">ME DeBakey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Korfer, R" uniqKey="Korfer R">R Körfer</name>
</author>
<author><name sortKey="El Banayosy, A" uniqKey="El Banayosy A">A El Banayosy</name>
</author>
<author><name sortKey="Morshuis, M" uniqKey="Morshuis M">M Morshuis</name>
</author>
<author><name sortKey="Tenderich, G" uniqKey="Tenderich G">G Tenderich</name>
</author>
<author><name sortKey="Reiss, N" uniqKey="Reiss N">N Reiss</name>
</author>
<author><name sortKey="Arusoglu, L" uniqKey="Arusoglu L">L Arusoglu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pohlmann, A" uniqKey="Pohlmann A">A Pohlmann</name>
</author>
<author><name sortKey="Lessmann, M" uniqKey="Lessmann M">M Lessmann</name>
</author>
<author><name sortKey="Finocchiaro, T" uniqKey="Finocchiaro T">T Finocchiaro</name>
</author>
<author><name sortKey="Fritschi, A" uniqKey="Fritschi A">A Fritschi</name>
</author>
<author><name sortKey="Steinseifer, U" uniqKey="Steinseifer U">U Steinseifer</name>
</author>
<author><name sortKey="Schmitz Rode, T" uniqKey="Schmitz Rode T">T Schmitz-Rode</name>
</author>
<author><name sortKey="Hameyer, K" uniqKey="Hameyer K">K Hameyer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Fritschi, Aj" uniqKey="Fritschi A">AJ Fritschi</name>
</author>
<author><name sortKey="Laumen, M" uniqKey="Laumen M">M Laumen</name>
</author>
<author><name sortKey="Finocchiaro, T" uniqKey="Finocchiaro T">T Finocchiaro</name>
</author>
<author><name sortKey="Halai, M" uniqKey="Halai M">M Halai</name>
</author>
<author><name sortKey="Spiliopoulos, S" uniqKey="Spiliopoulos S">S Spiliopoulos</name>
</author>
<author><name sortKey="Schulte Eistrup, S" uniqKey="Schulte Eistrup S">S Schulte-Eistrup</name>
</author>
<author><name sortKey="Egger, C" uniqKey="Egger C">C Egger</name>
</author>
<author><name sortKey="Schmitz Rode, T" uniqKey="Schmitz Rode T">T Schmitz-Rode</name>
</author>
<author><name sortKey="Steinseifer, U" uniqKey="Steinseifer U">U Steinseifer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Laumen, M" uniqKey="Laumen M">M Laumen</name>
</author>
<author><name sortKey="Finocchiaro, T" uniqKey="Finocchiaro T">T Finocchiaro</name>
</author>
<author><name sortKey="Schmitz Rode, T" uniqKey="Schmitz Rode T">T Schmitz-Rode</name>
</author>
<author><name sortKey="Korfer, R" uniqKey="Korfer R">R Körfer</name>
</author>
<author><name sortKey="Banayosy, Ae" uniqKey="Banayosy A">AE Banayosy</name>
</author>
<author><name sortKey="Steinseifer, U" uniqKey="Steinseifer U">U Steinseifer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Laumen, M" uniqKey="Laumen M">M Laumen</name>
</author>
<author><name sortKey="Finocchiaro, T" uniqKey="Finocchiaro T">T Finocchiaro</name>
</author>
<author><name sortKey="Fritschi, A" uniqKey="Fritschi A">A Fritschi</name>
</author>
<author><name sortKey="Cuenca Navalon, E" uniqKey="Cuenca Navalon E">E Cuenca Navalon</name>
</author>
<author><name sortKey="Schmitz Rode, T" uniqKey="Schmitz Rode T">T Schmitz-Rode</name>
</author>
<author><name sortKey="Morshuis, M" uniqKey="Morshuis M">M Morshuis</name>
</author>
<author><name sortKey="Koerfer, R" uniqKey="Koerfer R">R Koerfer</name>
</author>
<author><name sortKey="Schulte Eistrup, S" uniqKey="Schulte Eistrup S">S Schulte-Eistrup</name>
</author>
<author><name sortKey="Steinseifer, U" uniqKey="Steinseifer U">U Steinseifer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dowling, Rd" uniqKey="Dowling R">RD Dowling</name>
</author>
<author><name sortKey="Gray, La" uniqKey="Gray L">LA Gray</name>
</author>
<author><name sortKey="Etoch, Sw" uniqKey="Etoch S">SW Etoch</name>
</author>
<author><name sortKey="Laks, H" uniqKey="Laks H">H Laks</name>
</author>
<author><name sortKey="Marelli, D" uniqKey="Marelli D">D Marelli</name>
</author>
<author><name sortKey="Samuels, L" uniqKey="Samuels L">L Samuels</name>
</author>
<author><name sortKey="Entwistle, J" uniqKey="Entwistle J">J Entwistle</name>
</author>
<author><name sortKey="Couper, G" uniqKey="Couper G">G Couper</name>
</author>
<author><name sortKey="Vlahakes, Gj" uniqKey="Vlahakes G">GJ Vlahakes</name>
</author>
<author><name sortKey="Frazier, Oh" uniqKey="Frazier O">OH Frazier</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dowling, Rd" uniqKey="Dowling R">RD Dowling</name>
</author>
<author><name sortKey="Gray, La" uniqKey="Gray L">LA Gray</name>
</author>
<author><name sortKey="Etoch, Sw" uniqKey="Etoch S">SW Etoch</name>
</author>
<author><name sortKey="Laks, H" uniqKey="Laks H">H Laks</name>
</author>
<author><name sortKey="Marelli, D" uniqKey="Marelli D">D Marelli</name>
</author>
<author><name sortKey="Samuels, L" uniqKey="Samuels L">L Samuels</name>
</author>
<author><name sortKey="Couper, G" uniqKey="Couper G">G Couper</name>
</author>
<author><name sortKey="Vlahakes, Gj" uniqKey="Vlahakes G">GJ Vlahakes</name>
</author>
<author><name sortKey="Frazier, Oh" uniqKey="Frazier O">OH Frazier</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dowling, Rd" uniqKey="Dowling R">RD Dowling</name>
</author>
<author><name sortKey="Etoch, Sw" uniqKey="Etoch S">SW Etoch</name>
</author>
<author><name sortKey="Gray, La" uniqKey="Gray L">LA Gray</name>
</author>
</analytic>
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</div1>
</back>
</TEI>
<affiliations><list><country><li>Allemagne</li>
</country>
<region><li>District de Cologne</li>
<li>Rhénanie-du-Nord-Westphalie</li>
</region>
<settlement><li>Aix-la-Chapelle</li>
</settlement>
</list>
<tree><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Fritschi, Andreas Johann" sort="Fritschi, Andreas Johann" uniqKey="Fritschi A" first="Andreas Johann" last="Fritschi">Andreas Johann Fritschi</name>
</region>
<name sortKey="Egger, Christina" sort="Egger, Christina" uniqKey="Egger C" first="Christina" last="Egger">Christina Egger</name>
<name sortKey="Finocchiaro, Thomas" sort="Finocchiaro, Thomas" uniqKey="Finocchiaro T" first="Thomas" last="Finocchiaro">Thomas Finocchiaro</name>
<name sortKey="Koerfer, Reiner" sort="Koerfer, Reiner" uniqKey="Koerfer R" first="Reiner" last="Koerfer">Reiner Koerfer</name>
<name sortKey="Laumen, Marco" sort="Laumen, Marco" uniqKey="Laumen M" first="Marco" last="Laumen">Marco Laumen</name>
<name sortKey="Schmitz Rode, Thomas" sort="Schmitz Rode, Thomas" uniqKey="Schmitz Rode T" first="Thomas" last="Schmitz-Rode">Thomas Schmitz-Rode</name>
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<name sortKey="Tenderich, Gero" sort="Tenderich, Gero" uniqKey="Tenderich G" first="Gero" last="Tenderich">Gero Tenderich</name>
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</tree>
</affiliations>
</record>
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