Posterior capsule opacification
Identifieur interne : 004471 ( Istex/Checkpoint ); précédent : 004470; suivant : 004472Posterior capsule opacification
Auteurs : David J. Apple [États-Unis] ; Kerry D. Solomon [États-Unis] ; Manfred R. Tetz [États-Unis] ; Ehud I. Assia [États-Unis] ; Elizabeth Y. Holland [États-Unis] ; Ulrich F. C. Legler [États-Unis] ; Julie C. Tsai [États-Unis] ; Victoria E. Castaneda [États-Unis] ; Judy P. Hoggatt [États-Unis] ; Alexandra M. P. Kostick [États-Unis]Source :
- Survey of Ophthalmology [ 0039-6257 ] ; 1992.
Abstract
A complication of extracapsular cataract extraction with or without posterior chamber intraocular lens (PC-IOL) implantation is posterior capsule opacification. This condition is usually secondary to a proliferation and migration of residual lens epithelial cells. Opacification may be reduced by atraumatic surgery and thorough cortical clean-up. Clinical, pathological and experimental studies have shown that use of hydrodissection, the continuous curvilinear capsulorhexis and specific IOL designs may help reduce the incidence of this complication. Capsular-fixated, one-piece all-polymethylmethacrylate PC-IOLs with a C-shaped loop configuration and a posterior convexity of the optic are effective. Polymethylmethacrylate loops that retain “memory” create a symmetric, radial stretch on the posterior capsule after in-the-bag placement, leading to a more complete contact between the posterior surface of the IOL optic and the taut capsule. This may help form a barrier against central migration of epithelial cells into the visual axis. Various pharmacological and immunological methods are being investigated but conclusive data on these modalities are not yet available.
Url:
DOI: 10.1016/0039-6257(92)90073-3
Affiliations:
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<front><div type="abstract" xml:lang="en">A complication of extracapsular cataract extraction with or without posterior chamber intraocular lens (PC-IOL) implantation is posterior capsule opacification. This condition is usually secondary to a proliferation and migration of residual lens epithelial cells. Opacification may be reduced by atraumatic surgery and thorough cortical clean-up. Clinical, pathological and experimental studies have shown that use of hydrodissection, the continuous curvilinear capsulorhexis and specific IOL designs may help reduce the incidence of this complication. Capsular-fixated, one-piece all-polymethylmethacrylate PC-IOLs with a C-shaped loop configuration and a posterior convexity of the optic are effective. Polymethylmethacrylate loops that retain “memory” create a symmetric, radial stretch on the posterior capsule after in-the-bag placement, leading to a more complete contact between the posterior surface of the IOL optic and the taut capsule. This may help form a barrier against central migration of epithelial cells into the visual axis. Various pharmacological and immunological methods are being investigated but conclusive data on these modalities are not yet available.</div>
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