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Thoughts on COVID-19 and autoimmune diseases

Identifieur interne : 000032 ( Pmc/Checkpoint ); précédent : 000031; suivant : 000033

Thoughts on COVID-19 and autoimmune diseases

Auteurs : Anca D. Askanase [États-Unis] ; Leila Khalili [États-Unis] ; Jill P. Buyon [États-Unis]

Source :

RBID : PMC:7174058

Abstract

Over the 2 months since coronavirus first appeared in China, cases have emerged on every continent, and it is clear that patients with autoimmune diseases might also be affected. Coronavirus disease 2019 (COVID-19) is a highly contagious viral illness with a mortality rate approaching 2%. Here we discuss the challenges that patients with autoimmune diseases might face and the information on using immunomodulatory therapies like chloroquine, tocilizumab and baricitinib to quench the cytokine storm in patients with very severe COVID-19 pneumonia.


Url:
DOI: 10.1136/lupus-2020-000396
PubMed: 32341791
PubMed Central: 7174058


Affiliations:


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PMC:7174058

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<p>Over the 2 months since coronavirus first appeared in China, cases have emerged on every continent, and it is clear that patients with autoimmune diseases might also be affected. Coronavirus disease 2019 (COVID-19) is a highly contagious viral illness with a mortality rate approaching 2%. Here we discuss the challenges that patients with autoimmune diseases might face and the information on using immunomodulatory therapies like chloroquine, tocilizumab and baricitinib to quench the cytokine storm in patients with very severe COVID-19 pneumonia.</p>
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