Serveur d'exploration Tocilizumab - Checkpoint (Ncbi)

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List of bibliographic references

Number of relevant bibliographic references: 678.
[20-40] [0 - 20][0 - 50][40-60]
Ident.Authors (with country if any)Title
000077 (2008) Yasuo Adachi [Japon] ; Naoko Yoshio-Hoshino ; Norihiro NishimotoThe blockade of IL-6 signaling in rational drug design.
000079 (2008) Atsuhiko Kato [Japon] ; Saori Matsuo ; Hirotake Takai ; Yasushi Uchiyama ; Masahiko Mihara ; Masami SuzukiEarly effects of tocilizumab on bone and bone marrow lesions in a collagen-induced arthritis monkey model.
000080 (2009) M. Hirao [Japon] ; J. Hashimoto ; H. Tsuboi ; A. Nampei ; H. Nakahara ; N. Yoshio ; T. Mima ; H. Yoshikawa ; N. NishimotoLaboratory and febrile features after joint surgery in patients with rheumatoid arthritis treated with tocilizumab.
000081 (2008) Yasushi Uchiyama [Japon] ; Keigo Yorozu ; Misato Hashizume ; Yoichiro Moriya ; Masahiko MiharaTocilizumab, a humanized anti-interleukin-6 receptor antibody, ameliorates joint swelling in established monkey collagen-induced arthritis.
000087 (2008) Yasushi Uchiyama [Japon] ; Hiroto Yoshida ; Nobuo Koike ; Naohiko Hayakawa ; Atsuko Sugita ; Takashi Nishimura ; Masahiko MiharaAnti-IL-6 receptor antibody increases blood IL-6 level via the blockade of IL-6 clearance, but not via the induction of IL-6 production.
000090 (2009) Shoko Nakajima [Japon] ; Takuya Naruto ; Takako Miyamae ; Tomoyuki Imagawa ; Masaaki Mori ; Shigeru Nishimaki ; Shumpei YokotaImprovement of reduced serum cartilage oligomeric matrix protein levels in systemic juvenile idiopathic arthritis patients treated with the anti-interleukin-6 receptor monoclonal antibody tocilizumab.
000091 (2009) Hiroshi Fujiwara [Japon] ; Norihiro Nishimoto ; Yoshimasa Hamano ; Nobuyuki Asanuma ; Shunji Miki ; Soji Kasayama ; Masaki SuemuraMasked early symptoms of pneumonia in patients with rheumatoid arthritis during tocilizumab treatment: a report of two cases.
000092 (2009) Hideko Nakahara [Japon] ; Toru Mima ; Naoko Yoshio-Hoshino ; Masato Matsushita ; Jun Hashimoto ; Norihiro NishimotoA case report of a patient with refractory adult-onset Still's disease who was successfully treated with tocilizumab over 6 years.
000095 (2008) Norihiro Nishimoto [Japon] ; Kimio Terao ; Toru Mima ; Hideko Nakahara ; Nobuhiro Takagi ; Takahiro KakehiMechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease.
000096 (2008) M. Hashizume [Japon] ; N. Hayakawa ; M. MiharaIL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17.
000098 (2009) Misato Hashizume [Japon] ; Masahiko MiharaInfluence of humanized anti-IL-6R antibody, tocilizumab on the activity of soluble gp130, natural inhibitor of IL-6 signaling.
000110 (2009) Norihiro Nishimoto [Japon] ; Nobuyuki Miyasaka ; Kazuhiko Yamamoto ; Shinichi Kawai ; Tsutomu Takeuchi ; Junichi Azuma ; Tadamitsu KishimotoStudy of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy.
000112 (2009) Fumiaki Sugiura [Japon] ; Toshihisa Kojima ; Takeshi Oguchi ; Shirou Urata ; Yukio Yuzawa ; Akihiro Sakakibara ; Hiroki Hayashi ; Norihiro Nishimoto ; Naoki IshiguroA case of peripheral neuropathy and skin ulcer in a patient with rheumatoid arthritis after a single infusion of tocilizumab.
000113 (2009) Atsuhiko Kato [Japon] ; Takeshi Watanabe ; Masaki Yamazaki ; Toshiaki Deki ; Masami SuzukiIL-6R distribution in normal human and cynomolgus monkey tissues.
000114 (2009) N. Nishimoto [Japon] ; N. Miyasaka ; K. Yamamoto ; S. Kawai ; T. Takeuchi ; J. AzumaLong-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study.
000124 (2009) Kazuko Matsumoto [Japon] ; Takao Nagashima ; Shino Takatori ; Yuta Kawahara ; Masaki Yagi ; Masahiro Iwamoto ; Hitoaki Okazaki ; Seiji MinotaGlucocorticoid and cyclosporine refractory adult onset Still's disease successfully treated with tocilizumab.
000134 (2009) Ryuji Nagamine [Japon] ; Weijia Chen ; Toshihiko Hara ; Keiichi Kondo ; Yoichi SugiokaImmediate reduction of white blood cell count after tocilizumab administration was observed in some cases.
000137 (????) Masahiko Mihara [Japon] ; Yoshiyuki Ohsugi ; Tadamitsu KishimotoEvidence for the role of Th17 cell inhibition in the prevention of autoimmune diseases by anti-interluekin-6 receptor antibody.
000138 (2009) Mareina Kudo [Japon] ; Hirofumi Jono ; Satoru Shinriki ; Shigetoshi Yano ; Hideo Nakamura ; Keishi Makino ; Takuichiro Hide ; Daisuke Muta ; Mitsuharu Ueda ; Kazutoshi Ota ; Yukio Ando ; Jun-Ichi KuratsuAntitumor effect of humanized anti-interleukin-6 receptor antibody (tocilizumab) on glioma cell proliferation. Laboratory investigation.
000141 (2009) Toru Mima [Japon] ; Norihiro NishimotoClinical value of blocking IL-6 receptor.
000148 (2009) Hiroe Sato [Japon] ; Takehito Sakai ; Toshiaki Sugaya ; Yasuhiro Otaki ; Kana Aoki ; Katsushi Ishii ; Hidehiro Horizono ; Hiroshi Otani ; Asami Abe ; Noboru Yamada ; Hajime Ishikawa ; Kiyoshi Nakazono ; Akira Murasawa ; Fumitake GejyoTocilizumab dramatically ameliorated life-threatening diarrhea due to secondary amyloidosis associated with rheumatoid arthritis.

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