StressCovidV1, PubMed, Corpus, bibRecord, 000990

Effect of vitamin E supplementation on lipid peroxidation in blood and lung of influenza virus infected mice.

Identifieur interne : 000990 ( PubMed/Corpus ); précédent : 000989; suivant : 000991

Effect of vitamin E supplementation on lipid peroxidation in blood and lung of influenza virus infected mice.

Auteurs : M. Mileva ; R. Bakalova ; L. Tancheva ; A. Galabov ; S. Ribarov

Source :

Comparative immunology, microbiology and infectious diseases [ 0147-9571 ] ; 2002.

RBID : pubmed:11831742

English descriptors

KwdEn :
- Animals, Antioxidants (pharmacology), Dietary Supplements, Dose-Response Relationship, Drug, Influenza A virus, Lipid Peroxidation (drug effects), Lung (metabolism), Male, Malondialdehyde (blood), Malondialdehyde (metabolism), Mice, Mice, Inbred ICR, Orthomyxoviridae Infections (metabolism), Oxidative Stress (drug effects), Time Factors, Vitamin E (blood), Vitamin E (metabolism), Vitamin E (pharmacology).
MESH :
- chemical , blood : Malondialdehyde, Vitamin E.
- chemical , metabolism : Malondialdehyde, Vitamin E.
- chemical , pharmacology : Antioxidants, Vitamin E.
- drug effects : Lipid Peroxidation, Oxidative Stress.
- metabolism : Lung, Orthomyxoviridae Infections.
- Animals, Dietary Supplements, Dose-Response Relationship, Drug, Influenza A virus, Male, Mice, Mice, Inbred ICR, Time Factors.

Abstract

The influenza virus infection (A/Aichi/2/68) was associated with development of oxidative stress in lung and blood of mice, accompanied by an increase in levels of lipid peroxidation products (conjugated dienes and total malondialdehyde) and a decrease in endogenous amounts of natural antioxidant vitamin E. These effects were most pronounced on the 5th day after virus inoculation, in comparison with those on the 7th. Supplementation of mice with exogenous vitamin E before virus inoculation lead to lung and blood protection against lipid peroxidation. A marked decrease in lipid peroxidation products and an increase in vitamin E content was established in blood and lung on the 5th and 7th day after virus inoculation. The stabilizing effect of vitamin E is dose-dependent in blood and dose-independent in lung, and was most pronounced on the 5th day after virus inoculation in comparison with the 7th day.

DOI: 10.1016/s0147-9571(01)00010-8
PubMed: 11831742

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pubmed:11831742

Le document en format XML

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<author><name sortKey="Mileva, M" sort="Mileva, M" uniqKey="Mileva M" first="M" last="Mileva">M. Mileva</name>
<affiliation><nlm:affiliation>Department of Medical Physics and Biophysics, Medical University, Sofia, Bulgaria.</nlm:affiliation>
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<author><name sortKey="Bakalova, R" sort="Bakalova, R" uniqKey="Bakalova R" first="R" last="Bakalova">R. Bakalova</name>
</author>
<author><name sortKey="Tancheva, L" sort="Tancheva, L" uniqKey="Tancheva L" first="L" last="Tancheva">L. Tancheva</name>
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<author><name sortKey="Galabov, A" sort="Galabov, A" uniqKey="Galabov A" first="A" last="Galabov">A. Galabov</name>
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<author><name sortKey="Ribarov, S" sort="Ribarov, S" uniqKey="Ribarov S" first="S" last="Ribarov">S. Ribarov</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Effect of vitamin E supplementation on lipid peroxidation in blood and lung of influenza virus infected mice.</title>
<author><name sortKey="Mileva, M" sort="Mileva, M" uniqKey="Mileva M" first="M" last="Mileva">M. Mileva</name>
<affiliation><nlm:affiliation>Department of Medical Physics and Biophysics, Medical University, Sofia, Bulgaria.</nlm:affiliation>
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<author><name sortKey="Bakalova, R" sort="Bakalova, R" uniqKey="Bakalova R" first="R" last="Bakalova">R. Bakalova</name>
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<author><name sortKey="Tancheva, L" sort="Tancheva, L" uniqKey="Tancheva L" first="L" last="Tancheva">L. Tancheva</name>
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<author><name sortKey="Galabov, A" sort="Galabov, A" uniqKey="Galabov A" first="A" last="Galabov">A. Galabov</name>
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<author><name sortKey="Ribarov, S" sort="Ribarov, S" uniqKey="Ribarov S" first="S" last="Ribarov">S. Ribarov</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Antioxidants (pharmacology)</term>
<term>Dietary Supplements</term>
<term>Dose-Response Relationship, Drug</term>
<term>Influenza A virus</term>
<term>Lipid Peroxidation (drug effects)</term>
<term>Lung (metabolism)</term>
<term>Male</term>
<term>Malondialdehyde (blood)</term>
<term>Malondialdehyde (metabolism)</term>
<term>Mice</term>
<term>Mice, Inbred ICR</term>
<term>Orthomyxoviridae Infections (metabolism)</term>
<term>Oxidative Stress (drug effects)</term>
<term>Time Factors</term>
<term>Vitamin E (blood)</term>
<term>Vitamin E (metabolism)</term>
<term>Vitamin E (pharmacology)</term>
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<term>Vitamin E</term>
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<term>Vitamin E</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antioxidants</term>
<term>Vitamin E</term>
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<term>Oxidative Stress</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lung</term>
<term>Orthomyxoviridae Infections</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Dietary Supplements</term>
<term>Dose-Response Relationship, Drug</term>
<term>Influenza A virus</term>
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<front><div type="abstract" xml:lang="en">The influenza virus infection (A/Aichi/2/68) was associated with development of oxidative stress in lung and blood of mice, accompanied by an increase in levels of lipid peroxidation products (conjugated dienes and total malondialdehyde) and a decrease in endogenous amounts of natural antioxidant vitamin E. These effects were most pronounced on the 5th day after virus inoculation, in comparison with those on the 7th. Supplementation of mice with exogenous vitamin E before virus inoculation lead to lung and blood protection against lipid peroxidation. A marked decrease in lipid peroxidation products and an increase in vitamin E content was established in blood and lung on the 5th and 7th day after virus inoculation. The stabilizing effect of vitamin E is dose-dependent in blood and dose-independent in lung, and was most pronounced on the 5th day after virus inoculation in comparison with the 7th day.</div>
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<DateRevised><Year>2019</Year>
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<Title>Comparative immunology, microbiology and infectious diseases</Title>
<ISOAbbreviation>Comp. Immunol. Microbiol. Infect. Dis.</ISOAbbreviation>
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<ArticleTitle>Effect of vitamin E supplementation on lipid peroxidation in blood and lung of influenza virus infected mice.</ArticleTitle>
<Pagination><MedlinePgn>1-11</MedlinePgn>
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<Abstract><AbstractText>The influenza virus infection (A/Aichi/2/68) was associated with development of oxidative stress in lung and blood of mice, accompanied by an increase in levels of lipid peroxidation products (conjugated dienes and total malondialdehyde) and a decrease in endogenous amounts of natural antioxidant vitamin E. These effects were most pronounced on the 5th day after virus inoculation, in comparison with those on the 7th. Supplementation of mice with exogenous vitamin E before virus inoculation lead to lung and blood protection against lipid peroxidation. A marked decrease in lipid peroxidation products and an increase in vitamin E content was established in blood and lung on the 5th and 7th day after virus inoculation. The stabilizing effect of vitamin E is dose-dependent in blood and dose-independent in lung, and was most pronounced on the 5th day after virus inoculation in comparison with the 7th day.</AbstractText>
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Effect of vitamin E supplementation on lipid peroxidation in blood and lung of influenza virus infected mice.

Effect of vitamin E supplementation on lipid peroxidation in blood and lung of influenza virus infected mice.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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