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Caregiving for children with developmental disabilities is associated with a poor antibody response to influenza vaccination.

Identifieur interne : 000749 ( PubMed/Corpus ); précédent : 000748; suivant : 000750

Caregiving for children with developmental disabilities is associated with a poor antibody response to influenza vaccination.

Auteurs : Stephen Gallagher ; Anna C. Phillips ; Mark T. Drayson ; Douglas Carroll

Source :

RBID : pubmed:19297308

English descriptors

Abstract

Older spousal caregivers of dementia patients have been found to show a relatively poor antibody response to medical vaccination. In the present case control study in a different caregiving environment, we sought to compare antibody responses to vaccination in parents of children with disabilities and parents of typically developing children.

DOI: 10.1097/PSY.0b013e31819d1910
PubMed: 19297308

Links to Exploration step

pubmed:19297308

Le document en format XML

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<nlm:affiliation>Centre for Health Psychology, Staffordshire University, Stoke-on-Trent, UK. S.Gallagher@staffs.ac.uk</nlm:affiliation>
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<name sortKey="Phillips, Anna C" sort="Phillips, Anna C" uniqKey="Phillips A" first="Anna C" last="Phillips">Anna C. Phillips</name>
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<name sortKey="Drayson, Mark T" sort="Drayson, Mark T" uniqKey="Drayson M" first="Mark T" last="Drayson">Mark T. Drayson</name>
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<name sortKey="Carroll, Douglas" sort="Carroll, Douglas" uniqKey="Carroll D" first="Douglas" last="Carroll">Douglas Carroll</name>
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<title xml:lang="en">Caregiving for children with developmental disabilities is associated with a poor antibody response to influenza vaccination.</title>
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<name sortKey="Phillips, Anna C" sort="Phillips, Anna C" uniqKey="Phillips A" first="Anna C" last="Phillips">Anna C. Phillips</name>
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<term>Adult</term>
<term>Antibody Formation (immunology)</term>
<term>Caregivers (psychology)</term>
<term>Caregivers (statistics & numerical data)</term>
<term>Child</term>
<term>Child Behavior Disorders (epidemiology)</term>
<term>Chronic Disease</term>
<term>Developmental Disabilities</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Influenza Vaccines (administration & dosage)</term>
<term>Influenza Vaccines (immunology)</term>
<term>Male</term>
<term>Stress, Psychological (psychology)</term>
<term>Surveys and Questionnaires</term>
<term>Vaccination (statistics & numerical data)</term>
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<term>Influenza Vaccines</term>
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<term>Child Behavior Disorders</term>
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<term>Antibody Formation</term>
<term>Influenza Vaccines</term>
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<term>Caregivers</term>
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<term>Caregivers</term>
<term>Vaccination</term>
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<term>Adult</term>
<term>Child</term>
<term>Chronic Disease</term>
<term>Developmental Disabilities</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
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<div type="abstract" xml:lang="en">Older spousal caregivers of dementia patients have been found to show a relatively poor antibody response to medical vaccination. In the present case control study in a different caregiving environment, we sought to compare antibody responses to vaccination in parents of children with disabilities and parents of typically developing children.</div>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Older spousal caregivers of dementia patients have been found to show a relatively poor antibody response to medical vaccination. In the present case control study in a different caregiving environment, we sought to compare antibody responses to vaccination in parents of children with disabilities and parents of typically developing children.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">At baseline assessment, 32 parents of children with developmental disabilities and 29 parents of typically developing children completed standard measures of perceived stress and child problem behaviors. They also provided a blood sample and were then vaccinated with the thymus-dependent trivalent influenza vaccine. Further blood samples were taken at 1- and 6-month follow-ups.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Relative to parents of typically developing children (mean titer = 458, standard deviation (SD) = 155.7 at 1 month follow-up and mean titer = 265, SD = 483.0 at 6-month follow-up), caregivers (mean titer = 219, SD = 528.4 at 1-month follow-up and 86, SD = 55.0 at 6-month follow-up) mounted a poorer antibody response than controls to the B/Malaysia strain of the vaccine.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The negative impact of caregiving on antibody response to vaccination would not seem to be restricted to older spousal caregivers, but is also evident in younger parents caring for children with developmental disabilities. The behavioral characteristics of the care recipients may be a determinant of whether or not antibody response to vaccination is compromised.</AbstractText>
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