StressCovidV1, PubMed, Corpus, bibRecord, 000666

Role of oxidative stress on diesel-enhanced influenza infection in mice.

Identifieur interne : 000666 ( PubMed/Corpus ); précédent : 000665; suivant : 000667

Role of oxidative stress on diesel-enhanced influenza infection in mice.

Auteurs : Kymberly M. Gowdy ; Quentin T. Krantz ; Charly King ; Elizabeth Boykin ; Ilona Jaspers ; William P. Linak ; M Ian Gilmour

Source :

Particle and fibre toxicology [ 1743-8977 ] ; 2010.

RBID : pubmed:21092162

English descriptors

KwdEn :
- Acetylcysteine (pharmacology), Air Pollutants (toxicity), Animals, Antioxidants (pharmacology), Cytokines (metabolism), Female, Humans, Influenza A virus, Interferon-gamma (biosynthesis), Interleukin-4 (biosynthesis), Lung (drug effects), Lung (immunology), Lung (virology), Mice, Mice, Inbred BALB C, Neutrophils (drug effects), Neutrophils (metabolism), Orthomyxoviridae Infections (immunology), Orthomyxoviridae Infections (metabolism), Orthomyxoviridae Infections (virology), Oxidative Stress, Th1 Cells (immunology), Th2 Cells (immunology), Vehicle Emissions (toxicity), Viral Load.
MESH :
- chemical , biosynthesis : Interferon-gamma, Interleukin-4.
- chemical , metabolism : Cytokines.
- chemical , pharmacology : Acetylcysteine, Antioxidants.
- chemical , toxicity : Air Pollutants, Vehicle Emissions.
- drug effects : Lung, Neutrophils.
- immunology : Lung, Orthomyxoviridae Infections, Th1 Cells, Th2 Cells.
- metabolism : Neutrophils, Orthomyxoviridae Infections.
- virology : Lung, Orthomyxoviridae Infections.
- Animals, Female, Humans, Influenza A virus, Mice, Mice, Inbred BALB C, Oxidative Stress, Viral Load.

Abstract

Numerous studies have shown that air pollutants, including diesel exhaust (DE), reduce host defenses, resulting in decreased resistance to respiratory infections. This study sought to determine if DE exposure could affect the severity of an ongoing influenza infection in mice, and examine if this could be modulated with antioxidants. BALB/c mice were treated by oropharyngeal aspiration with 50 plaque forming units of influenza A/HongKong/8/68 and immediately exposed to air or 0.5 mg/m3 DE (4 hrs/day, 14 days). Mice were necropsied on days 1, 4, 8 and 14 post-infection and lungs were assessed for virus titers, lung inflammation, immune cytokine expression and pulmonary responsiveness (PR) to inhaled methacholine. Exposure to DE during the course of infection caused an increase in viral titers at days 4 and 8 post-infection, which was associated with increased neutrophils and protein in the BAL, and an early increase in PR. Increased virus load was not caused by decreased interferon levels, since IFN-β levels were enhanced in these mice. Expression and production of IL-4 was significantly increased on day 1 and 4 p.i. while expression of the Th1 cytokines, IFN-γ and IL-12p40 was decreased. Treatment with the antioxidant N-acetylcysteine did not affect diesel-enhanced virus titers but blocked the DE-induced changes in cytokine profiles and lung inflammation. We conclude that exposure to DE during an influenza infection polarizes the local immune responses to an IL-4 dominated profile in association with increased viral disease, and some aspects of this effect can be reversed with antioxidants.

DOI: 10.1186/1743-8977-7-34
PubMed: 21092162

Links to Exploration step

pubmed:21092162

Le document en format XML

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<term>Orthomyxoviridae Infections (virology)</term>
<term>Oxidative Stress</term>
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<front><div type="abstract" xml:lang="en">Numerous studies have shown that air pollutants, including diesel exhaust (DE), reduce host defenses, resulting in decreased resistance to respiratory infections. This study sought to determine if DE exposure could affect the severity of an ongoing influenza infection in mice, and examine if this could be modulated with antioxidants. BALB/c mice were treated by oropharyngeal aspiration with 50 plaque forming units of influenza A/HongKong/8/68 and immediately exposed to air or 0.5 mg/m3 DE (4 hrs/day, 14 days). Mice were necropsied on days 1, 4, 8 and 14 post-infection and lungs were assessed for virus titers, lung inflammation, immune cytokine expression and pulmonary responsiveness (PR) to inhaled methacholine. Exposure to DE during the course of infection caused an increase in viral titers at days 4 and 8 post-infection, which was associated with increased neutrophils and protein in the BAL, and an early increase in PR. Increased virus load was not caused by decreased interferon levels, since IFN-β levels were enhanced in these mice. Expression and production of IL-4 was significantly increased on day 1 and 4 p.i. while expression of the Th1 cytokines, IFN-γ and IL-12p40 was decreased. Treatment with the antioxidant N-acetylcysteine did not affect diesel-enhanced virus titers but blocked the DE-induced changes in cytokine profiles and lung inflammation. We conclude that exposure to DE during an influenza infection polarizes the local immune responses to an IL-4 dominated profile in association with increased viral disease, and some aspects of this effect can be reversed with antioxidants.</div>
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<Abstract><AbstractText>Numerous studies have shown that air pollutants, including diesel exhaust (DE), reduce host defenses, resulting in decreased resistance to respiratory infections. This study sought to determine if DE exposure could affect the severity of an ongoing influenza infection in mice, and examine if this could be modulated with antioxidants. BALB/c mice were treated by oropharyngeal aspiration with 50 plaque forming units of influenza A/HongKong/8/68 and immediately exposed to air or 0.5 mg/m3 DE (4 hrs/day, 14 days). Mice were necropsied on days 1, 4, 8 and 14 post-infection and lungs were assessed for virus titers, lung inflammation, immune cytokine expression and pulmonary responsiveness (PR) to inhaled methacholine. Exposure to DE during the course of infection caused an increase in viral titers at days 4 and 8 post-infection, which was associated with increased neutrophils and protein in the BAL, and an early increase in PR. Increased virus load was not caused by decreased interferon levels, since IFN-β levels were enhanced in these mice. Expression and production of IL-4 was significantly increased on day 1 and 4 p.i. while expression of the Th1 cytokines, IFN-γ and IL-12p40 was decreased. Treatment with the antioxidant N-acetylcysteine did not affect diesel-enhanced virus titers but blocked the DE-induced changes in cytokine profiles and lung inflammation. We conclude that exposure to DE during an influenza infection polarizes the local immune responses to an IL-4 dominated profile in association with increased viral disease, and some aspects of this effect can be reversed with antioxidants.</AbstractText>
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<ReferenceList><Reference><Citation>Virology. 2000 Mar 30;269(1):66-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10725199</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Environ Res. 1985 Jun;37(1):44-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2581774</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Respir Crit Care Med. 2000 Jul;162(1):161-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10903236</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Circulation. 2004 Jan 6;109(1):71-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14676145</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2001 Nov 15;167(10):5868-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11698462</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Interferon Cytokine Res. 2010 Jun;30(6):439-49</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20235626</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Respir Crit Care Med. 1999 Mar;159(3):702-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10051240</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Exp Immunol. 2001 Mar;123(3):350-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11298119</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Environ Health Perspect. 2004 Jun;112(8):820-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15175167</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Exp Lung Res. 2007 Jun-Jul;33(5):227-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17620185</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Occup Environ Med. 1999 Aug;56(8):527-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10492649</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Allergy Clin Immunol. 2006 Aug;118(2):455-65</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16890772</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Environ Health Perspect. 2001 May;109(5):515-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11401764</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Immunopharmacology. 1988 Mar-Apr;15(2):103-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3372226</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pediatr Res. 2004 Apr;55(4):657-65</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14711892</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respir Res. 2010;11:14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20122285</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respirology. 2000 Jun;5(2):197-203</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10894110</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>JAMA. 2004 Sep 15;292(11):1333-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15367555</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Toxicol Sci. 2004 Feb;77(2):263-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14657513</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2003 Dec 12;278(50):50781-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14522998</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vet Pathol. 1996 Jan;33(1):43-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8826005</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2000 Sep 15;165(6):3393-401</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10975858</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 1999 Nov 15;163(10):5582-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10553087</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Exp Immunol. 2000 May;120(2):356-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10792388</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mech Ageing Dev. 1997 Mar;94(1-3):25-39</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9147358</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Allergy Clin Immunol. 2000 Dec;106(6):1140-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11112898</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respir Res. 2008;9:57</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18671884</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2008;4(8):e1000115</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18670648</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2003 Nov 15;171(10):5107-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14607909</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Allergy. 1997;52(38 Suppl):52-6; discussion 57-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9208060</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1999 Oct 22;274(43):31025-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10521501</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1996 Aug;70(8):5230-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8764032</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Environ Health Perspect. 2001 Aug;109 Suppl 4:619-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11544174</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Allergy Clin Immunol. 2007 May;119(5):1225-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17335885</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Respir Cell Mol Biol. 2001 Jun;24(6):769-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11415944</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Inhal Toxicol. 2002 May;14(5):459-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12028803</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Physiol Lung Cell Mol Physiol. 2002 Mar;282(3):L563-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11839553</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1154-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16399790</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 1994 Aug 1;153(3):1246-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8027552</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>DNA Cell Biol. 2004 Jun;23(6):341-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15231067</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Toxicol Sci. 2005 Jun;85(2):990-1002</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15772371</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol Methods. 2001 Aug;96(2):107-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11445142</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Inhal Toxicol. 2004 May;16(5):311-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15371182</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int Rev Immunol. 2002 Jul-Oct;21(4-5):339-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12486818</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respiration. 1984;46(2):218-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6494618</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Respir Cell Mol Biol. 2003 Apr;28(4):451-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12654634</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am Rev Respir Dis. 1977 Mar;115(3):479-514</Citation>
<ArticleIdList><ArticleId IdType="pubmed">320925</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 1999 Jul 30;17 Suppl 1:S42-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10471179</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Inhal Toxicol. 2007 Nov;19(14):1121-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17987464</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Exp Med. 1993 Feb 1;177(2):475-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8426116</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Chem Res Toxicol. 2005 May;18(5):896-903</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15892584</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am Rev Respir Dis. 1992 May;145(5):1123-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1586057</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Environ Health Perspect. 2001 Aug;109 Suppl 4:609-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11544172</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Inhal Toxicol. 2007 Nov;19(14):1135-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17987465</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Allergy Clin Immunol. 2002 May;109(5):847-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11994710</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Inhal Toxicol. 2004 Dec 1;16(13):835-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15513815</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Pharmacol Toxicol Methods. 1998 Apr;39(3):163-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9741391</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Physiol. 1999 Sep;277(3 Pt 1):L580-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10484466</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1996 Jul;70(7):4411-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8676464</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur Respir J. 2000 Jun;15(6):1046-51</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10885423</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Feb;30(2):238-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1376372</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Contact Dermatitis. 1994 Jul;31(1):55-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7523022</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1998 Jun;72(6):4825-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9573248</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2004 Aug 15;39(4):459-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15356805</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Chim Acta. 1998 Jul 28;275(2):175-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9721075</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Part Fibre Toxicol. 2009 Aug 14;6:22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19682371</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>JAMA. 2003 Jan 8;289(2):179-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12517228</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3071-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9501217</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Microbiol Rev. 2000 Jul;13(3):371-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10885982</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2009 Dec 1;183(11):7441-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19917678</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Exp Immunol. 2005 Jul;141(1):107-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15958076</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Toxicol Appl Pharmacol. 2008 Jun 15;229(3):310-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18343473</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2002 Mar 1;168(5):2560-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11859152</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>

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Role of oxidative stress on diesel-enhanced influenza infection in mice.

Role of oxidative stress on diesel-enhanced influenza infection in mice.

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