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The state of oxidative homeostasis in children with influenza stomatitis.

Identifieur interne : 000210 ( PubMed/Corpus ); précédent : 000209; suivant : 000211

The state of oxidative homeostasis in children with influenza stomatitis.

Auteurs : Nataliia O. Gevkaliuk ; Nataliya I. Sydliaruk ; Larysa Ya Posolenyk ; Oksana Ya Vydoinyk ; Lesia I. Kuchyrka

Source :

RBID : pubmed:31050989

English descriptors

Abstract

Introduction: The clinical course of acute respiratory viral infections was not sufficiently studied, specially the state of oxidative homeostasis in children with influenza stomatitis. This fact became the base for our study. The aim: to characterize the state of oxidative-prooxidant system as one of the factors of non-specific resistance of children` organism with influenza stomatitis.

PubMed: 31050989

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pubmed:31050989

Le document en format XML

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<name sortKey="Gevkaliuk, Nataliia O" sort="Gevkaliuk, Nataliia O" uniqKey="Gevkaliuk N" first="Nataliia O" last="Gevkaliuk">Nataliia O. Gevkaliuk</name>
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<nlm:affiliation>State Institution Of Higher Education "I. Horbachevsky Ternopil State Medical University", Ternopil, Ukraine.</nlm:affiliation>
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<name sortKey="Sydliaruk, Nataliya I" sort="Sydliaruk, Nataliya I" uniqKey="Sydliaruk N" first="Nataliya I" last="Sydliaruk">Nataliya I. Sydliaruk</name>
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<nlm:affiliation>State Institution Of Higher Education "I. Horbachevsky Ternopil State Medical University", Ternopil, Ukraine.</nlm:affiliation>
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<name sortKey="Posolenyk, Larysa Ya" sort="Posolenyk, Larysa Ya" uniqKey="Posolenyk L" first="Larysa Ya" last="Posolenyk">Larysa Ya Posolenyk</name>
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<nlm:affiliation>State Institution Of Higher Education "I. Horbachevsky Ternopil State Medical University", Ternopil, Ukraine.</nlm:affiliation>
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<name sortKey="Vydoinyk, Oksana Ya" sort="Vydoinyk, Oksana Ya" uniqKey="Vydoinyk O" first="Oksana Ya" last="Vydoinyk">Oksana Ya Vydoinyk</name>
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<nlm:affiliation>State Institution Of Higher Education "I. Horbachevsky Ternopil State Medical University", Ternopil, Ukraine.</nlm:affiliation>
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<name sortKey="Kuchyrka, Lesia I" sort="Kuchyrka, Lesia I" uniqKey="Kuchyrka L" first="Lesia I" last="Kuchyrka">Lesia I. Kuchyrka</name>
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<title level="j">Wiadomosci lekarskie (Warsaw, Poland : 1960)</title>
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<term>Antioxidants (therapeutic use)</term>
<term>Ceruloplasmin (metabolism)</term>
<term>Child</term>
<term>Homeostasis</term>
<term>Humans</term>
<term>Infant</term>
<term>Influenza, Human</term>
<term>Lipid Peroxidation</term>
<term>Oxidative Stress (drug effects)</term>
<term>Stomatitis</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en">
<term>Ceruloplasmin</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Antioxidants</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en">
<term>Oxidative Stress</term>
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<keywords scheme="MESH" xml:lang="en">
<term>Child</term>
<term>Homeostasis</term>
<term>Humans</term>
<term>Infant</term>
<term>Influenza, Human</term>
<term>Lipid Peroxidation</term>
<term>Stomatitis</term>
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<div type="abstract" xml:lang="en">Introduction: The clinical course of acute respiratory viral infections was not sufficiently studied, specially the state of oxidative homeostasis in children with influenza stomatitis. This fact became the base for our study. The aim: to characterize the state of oxidative-prooxidant system as one of the factors of non-specific resistance of children` organism with influenza stomatitis.</div>
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<Month>08</Month>
<Day>21</Day>
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<Year>2019</Year>
<Month>08</Month>
<Day>21</Day>
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<Volume>72</Volume>
<Issue>3</Issue>
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<Year>2019</Year>
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<Title>Wiadomosci lekarskie (Warsaw, Poland : 1960)</Title>
<ISOAbbreviation>Wiad. Lek.</ISOAbbreviation>
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<ArticleTitle>The state of oxidative homeostasis in children with influenza stomatitis.</ArticleTitle>
<Pagination>
<MedlinePgn>405-408</MedlinePgn>
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<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Introduction: The clinical course of acute respiratory viral infections was not sufficiently studied, specially the state of oxidative homeostasis in children with influenza stomatitis. This fact became the base for our study. The aim: to characterize the state of oxidative-prooxidant system as one of the factors of non-specific resistance of children` organism with influenza stomatitis.</AbstractText>
<AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">Materials and methods: A survey was conducted on 384 children with acute respiratory viral infections aged from 6 months to 12 years, among them 318 had lesions of oral cavity. The mild form was diagnosed in 52 children, moderately severe - in 185, severe - in 81 children. The control group consisted of children without lesions of oral cavity (66 people). To analyze lipid peroxidation we used a spectrophotometric determination of diene conjugates. The ceruloplasmin activity and the transferrin saturation in blood plasma by iron were determined by G. Babenko's method.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Results: We found the intensification of lipid peroxidation: a significant increase of diene conjugates in serum up to 13.78 %, the level of which depended on the severity of disease. We also found the activity increase of ceruloplasmin in 1,8 times in patients with severe course of disease. The saturation of blood plasma transferrin by iron was significantly reduced - for 15.27 % in patients with severe course of influenza stomatitis.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Conclusions: Changes in antioxidant system happend due to the activation of lipid peroxidation, and because of the inability to neutralize toxic metabolites in the children` body the intoxication syndrome developed.</AbstractText>
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<DescriptorName UI="D013280" MajorTopicYN="Y">Stomatitis</DescriptorName>
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