Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19.
Identifieur interne : 000035 ( PubMed/Corpus ); précédent : 000034; suivant : 000036Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19.
Auteurs : Samad Ghaffari ; Neda Roshanravan ; Helda Tutunchi ; Alireza Ostadrahimi ; Mahboub Pouraghaei ; Behnam KafilSource :
- Archives of medical research [ 1873-5487 ] ; 2020.
Abstract
The current outbreak of COVID-19 (coronavirus) has been identified by World Health Organization (WHO) as a global pandemic. With the emergence of the COVID-19 virus and considering the lack of effective pharmaceutical treatment for it, there is an urgent need to identify safe and effective drugs or potential adjuvant therapy in this regard. Bioactive lipids with an array of known health-promoting properties can be suggested as effective agents in alleviating acute respiratory stress induced by virus. The bioactive lipid amide, oleoylethanolamide (OEA), due to several distinctive homeostatic properties, including anti-inflammatory activities, modulation of immune response, and anti-oxidant effects can be considered as a novel potential pharmacological alternative for the management of COVID-19.
DOI: 10.1016/j.arcmed.2020.04.006
PubMed: 32327293
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Electronic address: Neda.roshanravan10@gmail.com.</nlm:affiliation></affiliation></author><author><name sortKey="Tutunchi, Helda" sort="Tutunchi, Helda" uniqKey="Tutunchi H" first="Helda" last="Tutunchi">Helda Tutunchi</name><affiliation><nlm:affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Ostadrahimi, Alireza" sort="Ostadrahimi, Alireza" uniqKey="Ostadrahimi A" first="Alireza" last="Ostadrahimi">Alireza Ostadrahimi</name><affiliation><nlm:affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Pouraghaei, Mahboub" sort="Pouraghaei, Mahboub" uniqKey="Pouraghaei M" first="Mahboub" last="Pouraghaei">Mahboub Pouraghaei</name><affiliation><nlm:affiliation>Emergency Medicine Research Team, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Kafil, Behnam" sort="Kafil, Behnam" uniqKey="Kafil B" first="Behnam" last="Kafil">Behnam Kafil</name><affiliation><nlm:affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32327293</idno><idno type="pmid">32327293</idno><idno type="doi">10.1016/j.arcmed.2020.04.006</idno><idno type="wicri:Area/PubMed/Corpus">000035</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000035</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19.</title><author><name sortKey="Ghaffari, Samad" sort="Ghaffari, Samad" uniqKey="Ghaffari S" first="Samad" last="Ghaffari">Samad Ghaffari</name><affiliation><nlm:affiliation>Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Roshanravan, Neda" sort="Roshanravan, Neda" uniqKey="Roshanravan N" first="Neda" last="Roshanravan">Neda Roshanravan</name><affiliation><nlm:affiliation>Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: Neda.roshanravan10@gmail.com.</nlm:affiliation></affiliation></author><author><name sortKey="Tutunchi, Helda" sort="Tutunchi, Helda" uniqKey="Tutunchi H" first="Helda" last="Tutunchi">Helda Tutunchi</name><affiliation><nlm:affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Ostadrahimi, Alireza" sort="Ostadrahimi, Alireza" uniqKey="Ostadrahimi A" first="Alireza" last="Ostadrahimi">Alireza Ostadrahimi</name><affiliation><nlm:affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Pouraghaei, Mahboub" sort="Pouraghaei, Mahboub" uniqKey="Pouraghaei M" first="Mahboub" last="Pouraghaei">Mahboub Pouraghaei</name><affiliation><nlm:affiliation>Emergency Medicine Research Team, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Kafil, Behnam" sort="Kafil, Behnam" uniqKey="Kafil B" first="Behnam" last="Kafil">Behnam Kafil</name><affiliation><nlm:affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Archives of medical research</title><idno type="eISSN">1873-5487</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The current outbreak of COVID-19 (coronavirus) has been identified by World Health Organization (WHO) as a global pandemic. With the emergence of the COVID-19 virus and considering the lack of effective pharmaceutical treatment for it, there is an urgent need to identify safe and effective drugs or potential adjuvant therapy in this regard. Bioactive lipids with an array of known health-promoting properties can be suggested as effective agents in alleviating acute respiratory stress induced by virus. The bioactive lipid amide, oleoylethanolamide (OEA), due to several distinctive homeostatic properties, including anti-inflammatory activities, modulation of immune response, and anti-oxidant effects can be considered as a novel potential pharmacological alternative for the management of COVID-19.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32327293</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>26</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-5487</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Apr</Month><Day>15</Day></PubDate></JournalIssue><Title>Archives of medical research</Title><ISOAbbreviation>Arch. Med. Res.</ISOAbbreviation></Journal><ArticleTitle>Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">S0188-4409(20)30475-6</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.arcmed.2020.04.006</ELocationID><Abstract><AbstractText>The current outbreak of COVID-19 (coronavirus) has been identified by World Health Organization (WHO) as a global pandemic. With the emergence of the COVID-19 virus and considering the lack of effective pharmaceutical treatment for it, there is an urgent need to identify safe and effective drugs or potential adjuvant therapy in this regard. Bioactive lipids with an array of known health-promoting properties can be suggested as effective agents in alleviating acute respiratory stress induced by virus. The bioactive lipid amide, oleoylethanolamide (OEA), due to several distinctive homeostatic properties, including anti-inflammatory activities, modulation of immune response, and anti-oxidant effects can be considered as a novel potential pharmacological alternative for the management of COVID-19.</AbstractText><CopyrightInformation>Copyright © 2020 IMSS. Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ghaffari</LastName><ForeName>Samad</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roshanravan</LastName><ForeName>Neda</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: Neda.roshanravan10@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tutunchi</LastName><ForeName>Helda</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ostadrahimi</LastName><ForeName>Alireza</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pouraghaei</LastName><ForeName>Mahboub</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Emergency Medicine Research Team, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kafil</LastName><ForeName>Behnam</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>04</Month><Day>15</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Arch Med Res</MedlineTA><NlmUniqueID>9312706</NlmUniqueID><ISSNLinking>0188-4409</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Bioactive lipids</Keyword><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Coronavirus</Keyword><Keyword MajorTopicYN="N">OEA</Keyword><Keyword MajorTopicYN="N">Oleoylethanolamide</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>04</Month><Day>05</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>04</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>04</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>4</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>4</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32327293</ArticleId><ArticleId IdType="pii">S0188-4409(20)30475-6</ArticleId><ArticleId IdType="doi">10.1016/j.arcmed.2020.04.006</ArticleId><ArticleId IdType="pmc">PMC7158763</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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