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[Acute respiratory distress syndrome during the 2009 H1N1 influenza A pandemic in Ecuador].

Identifieur interne : 000A84 ( PubMed/Checkpoint ); précédent : 000A83; suivant : 000A85

[Acute respiratory distress syndrome during the 2009 H1N1 influenza A pandemic in Ecuador].

Auteurs : G. Paredes [Équateur] ; C. Cevallos

Source :

RBID : pubmed:20546973

Descripteurs français

English descriptors

Abstract

Among the most severe complications caused by the influenza A virus H1N1 pandemic is the Acute Respiratory Distress Syndrome (ARDS). The main objective of this study was to assess mortality after applying a strict protocol of ventilatory management and to describe the clinical characteristics of the patients.

DOI: 10.1016/j.medin.2010.03.011
PubMed: 20546973


Affiliations:


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pubmed:20546973

Le document en format XML

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<title xml:lang="en">[Acute respiratory distress syndrome during the 2009 H1N1 influenza A pandemic in Ecuador].</title>
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<nlm:affiliation>Unidad de Cuidados Intensivos, Hospital Enrique Garcés, Quito, Ecuador. rogergustavo26@hotmail.com</nlm:affiliation>
<country xml:lang="fr">Équateur</country>
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<term>Ecuador</term>
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<term>Influenza, Human</term>
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<term>Influenza, Human</term>
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<term>Respiratory Distress Syndrome, Adult</term>
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<term>Respiratory Distress Syndrome, Adult</term>
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<term>Grippe humaine</term>
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<term>Syndrome de détresse respiratoire de l'adulte</term>
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<div type="abstract" xml:lang="en">Among the most severe complications caused by the influenza A virus H1N1 pandemic is the Acute Respiratory Distress Syndrome (ARDS). The main objective of this study was to assess mortality after applying a strict protocol of ventilatory management and to describe the clinical characteristics of the patients.</div>
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<Month>09</Month>
<Day>16</Day>
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<Month>10</Month>
<Day>21</Day>
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<Volume>34</Volume>
<Issue>5</Issue>
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<MedlineDate>2010 Jun-Jul</MedlineDate>
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<Title>Medicina intensiva</Title>
<ISOAbbreviation>Med Intensiva</ISOAbbreviation>
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<ArticleTitle>[Acute respiratory distress syndrome during the 2009 H1N1 influenza A pandemic in Ecuador].</ArticleTitle>
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<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Among the most severe complications caused by the influenza A virus H1N1 pandemic is the Acute Respiratory Distress Syndrome (ARDS). The main objective of this study was to assess mortality after applying a strict protocol of ventilatory management and to describe the clinical characteristics of the patients.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">A prospective cohort study.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Intensive care unit (ICU) of the Hospital Enrique Garcés of the City of Quito.</AbstractText>
<AbstractText Label="PATIENTS" NlmCategory="METHODS">Patients admitted to the ICU with a diagnosis of severe pneumonia, ARDS, and high suspicion of influenza A H1N1.</AbstractText>
<AbstractText Label="PRIMARY VARIABLES OF INTEREST" NlmCategory="METHODS">Demographic variables, severity, diagnostic scores of community-acquired pneumonia, ventilator management protocol and mortality at 28 days, as principal effect of the study, were collected.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">24 patients were studied, 100% with a diagnosis of ARDS, mean age 41.1 (+/-14.8). Severe viral pneumonia predominated in these patients, mean APACHE was 18, average PaO(2)/FiO(2) on admission was 74.9, 100% had multisystemic involvement. A total of 91.3% received oseltamivir 150 mg w/12h for 14 days, the mean time between onset of symptoms and antiviral administration was 6.74 days. Intra-ICU mortality was 16.6%, and 28 days was 16.6%.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">After applying a strict management protocol for ventilatory management, mortality in this patient group was 16.6. We also stress that obesity and early renal failure were independent risk factors for mortality.</AbstractText>
<CopyrightInformation>Copyright (c) 2009 Elsevier España, S.L. y SEMICYUC. All rights reserved.</CopyrightInformation>
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<Affiliation>Unidad de Cuidados Intensivos, Hospital Enrique Garcés, Quito, Ecuador. rogergustavo26@hotmail.com</Affiliation>
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