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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) infection</title>
<author><name sortKey="Delgado Roche, Livan" sort="Delgado Roche, Livan" uniqKey="Delgado Roche L" first="Livan" last="Delgado-Roche">Livan Delgado-Roche</name>
<affiliation><nlm:aff id="aff1">Gerencia de Investigación Clínica, Dirección Médica, Laboratorios Liomont S.A. de C.V., Ciudad de México, México</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mesta, Fernando" sort="Mesta, Fernando" uniqKey="Mesta F" first="Fernando" last="Mesta">Fernando Mesta</name>
<affiliation><nlm:aff id="aff2">Escuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, Guillermo Massieu, Ciudad de México, México</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmc">7190501</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190501</idno>
<idno type="RBID">PMC:7190501</idno>
<idno type="doi">10.1016/j.arcmed.2020.04.019</idno>
<idno type="pmid">NONE</idno>
<date when="2020">2020</date>
<idno type="wicri:Area/Pmc/Corpus">000867</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000867</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) infection</title>
<author><name sortKey="Delgado Roche, Livan" sort="Delgado Roche, Livan" uniqKey="Delgado Roche L" first="Livan" last="Delgado-Roche">Livan Delgado-Roche</name>
<affiliation><nlm:aff id="aff1">Gerencia de Investigación Clínica, Dirección Médica, Laboratorios Liomont S.A. de C.V., Ciudad de México, México</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mesta, Fernando" sort="Mesta, Fernando" uniqKey="Mesta F" first="Fernando" last="Mesta">Fernando Mesta</name>
<affiliation><nlm:aff id="aff2">Escuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, Guillermo Massieu, Ciudad de México, México</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Archives of Medical Research</title>
<idno type="ISSN">0188-4409</idno>
<idno type="eISSN">1873-5487</idno>
<imprint><date when="2020">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>The emergence of viral respiratory pathogens with pandemic potential, such as severe acute respiratory syndrome coronavirus (SARS-CoV), the pathogenic agent of Covid-19, represent a serious health problem worldwide. Respiratory viral infections are, in general, associated with cytokine production, inflammation, cell death, and other pathophysiological processes, which could be link with a redox imbalance or oxidative stress. These phenomena are substantially increased during aging. Actually, severity and mortality risk of SARS-CoV-2 infection or Covid-19 disease have been associated with the age. The aim of the present work was to contribute with the understanding of the possible link between oxidative stress and the pathogenesis, severity and mortality risk in patients affected by SARS-CoV infection.</p>
</div>
</front>
</TEI>
<pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Arch Med Res</journal-id>
<journal-id journal-id-type="iso-abbrev">Arch. Med. Res</journal-id>
<journal-title-group><journal-title>Archives of Medical Research</journal-title>
</journal-title-group>
<issn pub-type="ppub">0188-4409</issn>
<issn pub-type="epub">1873-5487</issn>
<publisher><publisher-name>Published by Elsevier Inc. on behalf of IMSS.</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmc">7190501</article-id>
<article-id pub-id-type="publisher-id">S0188-4409(20)30540-3</article-id>
<article-id pub-id-type="doi">10.1016/j.arcmed.2020.04.019</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) infection</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" id="au1"><name><surname>Delgado-Roche</surname>
<given-names>Livan</given-names>
</name>
<email>ldelgadoroche@gmail.com</email>
<xref rid="aff1" ref-type="aff">a</xref>
<xref rid="cor1" ref-type="corresp">∗</xref>
</contrib>
<contrib contrib-type="author" id="au2"><name><surname>Mesta</surname>
<given-names>Fernando</given-names>
</name>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
<aff id="aff1"><label>a</label>
Gerencia de Investigación Clínica, Dirección Médica, Laboratorios Liomont S.A. de C.V., Ciudad de México, México</aff>
<aff id="aff2"><label>b</label>
Escuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, Guillermo Massieu, Ciudad de México, México</aff>
</contrib-group>
<author-notes><corresp id="cor1"><label>∗</label>
Address reprint requests to: Livan Delgado-Roche, Dr., Ph.D. Gerencia de Investigación Clínica, Dirección Médica, Laboratorios Liomont S.A. de C.V., Carretera México Toluca, 5420, Colonia El Yaqui, Alcaldía Cuajimalpa de Morelos, 05320, Ciudad de México, México. Phone: (+52) (55) 5814-1510; FAX: (+52) (55) 5814-1200; <email>ldelgadoroche@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="pmc-release"><day>30</day>
<month>4</month>
<year>2020</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="epub"><day>30</day>
<month>4</month>
<year>2020</year>
</pub-date>
<history><date date-type="received"><day>12</day>
<month>4</month>
<year>2020</year>
</date>
<date date-type="accepted"><day>24</day>
<month>4</month>
<year>2020</year>
</date>
</history>
<permissions><copyright-statement>© 2020 Published by Elsevier Inc. on behalf of IMSS.</copyright-statement>
<copyright-year>2020</copyright-year>
<copyright-holder></copyright-holder>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<abstract id="abs0010"><p>The emergence of viral respiratory pathogens with pandemic potential, such as severe acute respiratory syndrome coronavirus (SARS-CoV), the pathogenic agent of Covid-19, represent a serious health problem worldwide. Respiratory viral infections are, in general, associated with cytokine production, inflammation, cell death, and other pathophysiological processes, which could be link with a redox imbalance or oxidative stress. These phenomena are substantially increased during aging. Actually, severity and mortality risk of SARS-CoV-2 infection or Covid-19 disease have been associated with the age. The aim of the present work was to contribute with the understanding of the possible link between oxidative stress and the pathogenesis, severity and mortality risk in patients affected by SARS-CoV infection.</p>
</abstract>
<abstract abstract-type="author-highlights" id="abs0015"><title>Highlights</title>
<p><list list-type="simple" id="ulist0010"><list-item id="u0010"><label>-</label>
<p id="p0010">Oxidative stress is associated with SARS-CoV pathogenesis</p>
</list-item>
<list-item id="u0015"><label>-</label>
<p id="p0015">Inflammation and oxidative stress contribute with SARS-CoV infection</p>
</list-item>
<list-item id="u0020"><label>-</label>
<p id="p0020">Covid-19 in aging patients could be associated with oxidative stress</p>
</list-item>
</list>
</p>
</abstract>
<kwd-group id="kwrds0010"><title>Key Words</title>
<kwd>SARS-CoV</kwd>
<kwd>Virus infection</kwd>
<kwd>Oxidative stress</kwd>
<kwd>Covid-19</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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