Associating Changes in the Immune System with Clinical Diseases for Interpretation in Risk Assessment
Identifieur interne : 000962 ( Pmc/Checkpoint ); précédent : 000961; suivant : 000963Associating Changes in the Immune System with Clinical Diseases for Interpretation in Risk Assessment
Auteurs : Michael I. Luster ; Dori R. Germolec ; Christine G. Parks ; Laura Blaciforti ; Michael Kashon ; Robert LuebkeSource :
- Current Protocols in Toxicology [ 1934-9254 ] ; 2004.
Abstract
This overview unit discusses the relationship between immunosuppression, a potential consequence of immunotoxicity, and disease progression. It also discusses other factors, such as stress and age, that affect disease susceptibility. These factors play an important role in risk assessment for exposures to environmental factors.
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DOI: 10.1002/0471140856.tx1801s20
PubMed: 23045101
PubMed Central: 7162383
Affiliations:
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<front><div type="abstract" xml:lang="en"><title>Abstract</title>
<p>This overview unit discusses the relationship between immunosuppression, a potential consequence of immunotoxicity, and disease progression. It also discusses other factors, such as stress and age, that affect disease susceptibility. These factors play an important role in risk assessment for exposures to environmental factors.</p>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Curr Protoc Toxicol</journal-id>
<journal-id journal-id-type="iso-abbrev">Curr Protoc Toxicol</journal-id>
<journal-id journal-id-type="doi">10.1002/(ISSN)1934-9262</journal-id>
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<issn pub-type="ppub">1934-9254</issn>
<issn pub-type="epub">1934-9262</issn>
<publisher><publisher-name>John Wiley and Sons Inc.</publisher-name>
<publisher-loc>Hoboken</publisher-loc>
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<article-meta><article-id pub-id-type="pmid">23045101</article-id>
<article-id pub-id-type="pmc">7162383</article-id>
<article-id pub-id-type="doi">10.1002/0471140856.tx1801s20</article-id>
<article-id pub-id-type="publisher-id">CPTX1801</article-id>
<article-categories><subj-group subj-group-type="article-subject-classification"><subject>Occupational and Environmental Health</subject>
</subj-group>
<subj-group subj-group-type="article-subject-classification"><subject>Toxicology</subject>
</subj-group>
<subj-group subj-group-type="article-subject-classification"><subject>Immunology</subject>
</subj-group>
<subj-group subj-group-type="article-subject-classification"><subject>Animal Models</subject>
</subj-group>
<subj-group subj-group-type="article-subject-classification"><subject>Immune Disease</subject>
</subj-group>
<subj-group subj-group-type="article-subject-classification"><subject>Toxicology</subject>
</subj-group>
<subj-group subj-group-type="article-subject-classification"><subject>Immunotoxicology</subject>
</subj-group>
<subj-group subj-group-type="overline"><subject>Unit</subject>
</subj-group>
<subj-group subj-group-type="heading"><subject>Unit</subject>
</subj-group>
</article-categories>
<title-group><article-title>Associating Changes in the Immune System with Clinical Diseases for Interpretation in Risk Assessment</article-title>
<alt-title alt-title-type="right-running-head">Associating Changes in the Immune System with Clinical Diseases</alt-title>
</title-group>
<contrib-group><contrib id="cptx1801-cr-0006" contrib-type="author"><name><surname>Luster</surname>
<given-names>Michael I.</given-names>
</name>
<xref ref-type="aff" rid="cptx1801-aff-0001"><sup>1</sup>
</xref>
</contrib>
<contrib id="cptx1801-cr-0007" contrib-type="author"><name><surname>Germolec</surname>
<given-names>Dori R.</given-names>
</name>
<xref ref-type="aff" rid="cptx1801-aff-0002"><sup>2</sup>
</xref>
</contrib>
<contrib id="cptx1801-cr-0008" contrib-type="author"><name><surname>Parks</surname>
<given-names>Christine G.</given-names>
</name>
<xref ref-type="aff" rid="cptx1801-aff-0002"><sup>2</sup>
</xref>
</contrib>
<contrib id="cptx1801-cr-0009" contrib-type="author"><name><surname>Blaciforti</surname>
<given-names>Laura</given-names>
</name>
<xref ref-type="aff" rid="cptx1801-aff-0001"><sup>1</sup>
</xref>
</contrib>
<contrib id="cptx1801-cr-0010" contrib-type="author"><name><surname>Kashon</surname>
<given-names>Michael</given-names>
</name>
<xref ref-type="aff" rid="cptx1801-aff-0001"><sup>1</sup>
</xref>
</contrib>
<contrib id="cptx1801-cr-0011" contrib-type="author"><name><surname>Luebke</surname>
<given-names>Robert</given-names>
</name>
<xref ref-type="aff" rid="cptx1801-aff-0003"><sup>3</sup>
</xref>
</contrib>
</contrib-group>
<aff id="cptx1801-aff-0001"><label><sup>1</sup>
</label>
<institution>National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention</institution>
<city>Morgantown</city>
<named-content content-type="country-part">West Virginia</named-content>
</aff>
<aff id="cptx1801-aff-0002"><label><sup>2</sup>
</label>
<institution>National Institute of Environmental Health Sciences, National Institutes of Health</institution>
<city>Research Triangle Park</city>
<named-content content-type="country-part">North Carolina</named-content>
</aff>
<aff id="cptx1801-aff-0003"><label><sup>3</sup>
</label>
<institution>U.S. Environmental Protection Agency</institution>
<city>Research Triangle Park North</city>
<named-content content-type="country-part">Carolina</named-content>
</aff>
<pub-date pub-type="epub"><day>15</day>
<month>6</month>
<year>2004</year>
</pub-date>
<pub-date pub-type="ppub"><month>5</month>
<year>2004</year>
</pub-date>
<volume>20</volume>
<issue>1</issue>
<issue-id pub-id-type="doi">10.1002/0471140856.2004.20.issue-1</issue-id>
<issue-title>Immunotoxicology</issue-title>
<fpage>1811</fpage>
<lpage>18120</lpage>
<permissions><pmc-comment> © John Wiley and Sons </pmc-comment>
<copyright-statement content-type="article-copyright">Copyright © 2004 John Wiley & Sons, Inc. All rights reserved.</copyright-statement>
<license><license-p>This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.</license-p>
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<abstract><title>Abstract</title>
<p>This overview unit discusses the relationship between immunosuppression, a potential consequence of immunotoxicity, and disease progression. It also discusses other factors, such as stress and age, that affect disease susceptibility. These factors play an important role in risk assessment for exposures to environmental factors.</p>
</abstract>
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<kwd id="cptx1801-kwd-0003">immune response</kwd>
<kwd id="cptx1801-kwd-0004">immune suppression</kwd>
</kwd-group>
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<page-count count="20"></page-count>
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</front>
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<affiliations><list></list>
<tree><noCountry><name sortKey="Blaciforti, Laura" sort="Blaciforti, Laura" uniqKey="Blaciforti L" first="Laura" last="Blaciforti">Laura Blaciforti</name>
<name sortKey="Germolec, Dori R" sort="Germolec, Dori R" uniqKey="Germolec D" first="Dori R." last="Germolec">Dori R. Germolec</name>
<name sortKey="Kashon, Michael" sort="Kashon, Michael" uniqKey="Kashon M" first="Michael" last="Kashon">Michael Kashon</name>
<name sortKey="Luebke, Robert" sort="Luebke, Robert" uniqKey="Luebke R" first="Robert" last="Luebke">Robert Luebke</name>
<name sortKey="Luster, Michael I" sort="Luster, Michael I" uniqKey="Luster M" first="Michael I." last="Luster">Michael I. Luster</name>
<name sortKey="Parks, Christine G" sort="Parks, Christine G" uniqKey="Parks C" first="Christine G." last="Parks">Christine G. Parks</name>
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