StressCovidV1, PascalFrancis, Corpus, bibRecord, 000013

Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse

Identifieur interne : 000013 ( PascalFrancis/Corpus ); précédent : 000012; suivant : 000014

Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse

Auteurs : Sarah M. Wilson ; Kathleen J. Sikkema ; Krista W. Ranby

Source :

AIDS Care : (Print) [ 0954-0121 ] ; 2014.

RBID : Francis:14-0175325

Descripteurs français

Pascal (Inist)
- Sexe, Facteur psychosocial, Observance médicamenteuse, Pharmacothérapie, Association médicamenteuse, Antirétroviral, Contexte, SIDA, Virus immunodéficience humaine, Enfant maltraité, Abus sexuel, Toxicomanie, Abus de substance, Modèle équation structurale, Santé publique, Santé mentale, Environnement social, Antiviral, Genre.

English descriptors

KwdEn :
- AIDS, Antiretroviral agent, Antiviral, Child abuse, Context, Drug addiction, Drug combination, Drug compliance, Gender, Human immunodeficiency virus, Mental health, Pharmacotherapy, Psychosocial factor, Public health, Sex, Sexual abuse, Social environment, Structural equation modeling, Substance abuse.

Abstract

This study aimed to examine gender moderation within a stress and coping model of HIV medication adherence in adults with a history of childhood sexual abuse (CSA). Sequelae of CSA, including negative coping, psychological distress, and drug use, interfere with adherence to highly active antiretroviral treatment (HAART). These obstacles to adherence are likely moderated by gender. Gender may particularly influence the mediational effect of drug use on adherence. Participants included 206 adults living with HIV/AIDS and CSA. Categorical/continuous variable methodology in a structural equation modeling framework was used to test a multigroup model with women and men. Gender significantly moderated several effects in the model. For women, the effect of psychological distress on HAART adherence was mediated by drug use and the effect of drug use on viral load was mediated by HAART adherence. Among men, drug use did not significantly impact adherence. Since gender appears to moderate the effect of drug use on medication adherence, it is particularly important to address drug use within the context of HIV disease management in women with a history of CSA. Further, interventions to increase HAART adherence should take trauma history, gender, and drug abuse into account when assessing efficacy.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 0954-0121`
A03		`1`		`@0 AIDS Care : (Print)`
A05				`@2 26`
A06				`@2 7-8`
A08	`01`	`1`	`ENG`	`@1 Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse`
A11	`01`	`1`		`@1 WILSON (Sarah M.)`
A11	`02`	`1`		`@1 SIKKEMA (Kathleen J.)`
A11	`03`	`1`		`@1 RANBY (Krista W.)`
A14	`01`			`@1 Department of Psychology and Neuroscience, Duke University @2 Durham, NC @3 USA @Z 1 aut. @Z 2 aut.`
A14	`02`			`@1 Duke Global Health Institute @2 Durham, NC @3 USA @Z 1 aut. @Z 2 aut.`
A14	`03`			`@1 Department of Psychology, University of Colorado Denver @2 Denver, CO @3 USA @Z 3 aut.`
A20				`@1 959-967`
A21				`@1 2014`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 22096 @5 354000502712540240`
A44				`@0 0000 @1 © 2014 INIST-CNRS. All rights reserved.`
A45				`@0 2 p.1/4`
A47	`01`	`1`		`@0 14-0175325`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 AIDS Care : (Print)`
A66	`01`			`@0 GBR`
C01	`01`		`ENG`	@0 This study aimed to examine gender moderation within a stress and coping model of HIV medication adherence in adults with a history of childhood sexual abuse (CSA). Sequelae of CSA, including negative coping, psychological distress, and drug use, interfere with adherence to highly active antiretroviral treatment (HAART). These obstacles to adherence are likely moderated by gender. Gender may particularly influence the mediational effect of drug use on adherence. Participants included 206 adults living with HIV/AIDS and CSA. Categorical/continuous variable methodology in a structural equation modeling framework was used to test a multigroup model with women and men. Gender significantly moderated several effects in the model. For women, the effect of psychological distress on HAART adherence was mediated by drug use and the effect of drug use on viral load was mediated by HAART adherence. Among men, drug use did not significantly impact adherence. Since gender appears to moderate the effect of drug use on medication adherence, it is particularly important to address drug use within the context of HIV disease management in women with a history of CSA. Further, interventions to increase HAART adherence should take trauma history, gender, and drug abuse into account when assessing efficacy.
C02	`01`	`X`		`@0 770D06B @1 IV`
C02	`02`	`X`		`@0 770D03E01 @1 IV`
C02	`03`	`X`		`@0 770D03E04 @1 IV`
C03	`01`	`X`	`FRE`	`@0 Sexe @5 01`
C03	`01`	`X`	`ENG`	`@0 Sex @5 01`
C03	`01`	`X`	`SPA`	`@0 Sexo @5 01`
C03	`02`	`X`	`FRE`	`@0 Facteur psychosocial @5 02`
C03	`02`	`X`	`ENG`	`@0 Psychosocial factor @5 02`
C03	`02`	`X`	`SPA`	`@0 Factor sicosocial @5 02`
C03	`03`	`X`	`FRE`	`@0 Observance médicamenteuse @5 03`
C03	`03`	`X`	`ENG`	`@0 Drug compliance @5 03`
C03	`03`	`X`	`SPA`	`@0 Observancia de la medicación @5 03`
C03	`04`	`X`	`FRE`	`@0 Pharmacothérapie @5 04`
C03	`04`	`X`	`ENG`	`@0 Pharmacotherapy @5 04`
C03	`04`	`X`	`SPA`	`@0 Farmacoterapia @5 04`
C03	`05`	`X`	`FRE`	`@0 Association médicamenteuse @5 05`
C03	`05`	`X`	`ENG`	`@0 Drug combination @5 05`
C03	`05`	`X`	`SPA`	`@0 Asociación medicamentosa @5 05`
C03	`06`	`X`	`FRE`	`@0 Antirétroviral @5 06`
C03	`06`	`X`	`ENG`	`@0 Antiretroviral agent @5 06`
C03	`06`	`X`	`SPA`	`@0 Antiretroviral @5 06`
C03	`07`	`X`	`FRE`	`@0 Contexte @5 07`
C03	`07`	`X`	`ENG`	`@0 Context @5 07`
C03	`07`	`X`	`SPA`	`@0 Contexto @5 07`
C03	`08`	`X`	`FRE`	`@0 SIDA @5 08`
C03	`08`	`X`	`ENG`	`@0 AIDS @5 08`
C03	`08`	`X`	`SPA`	`@0 SIDA @5 08`
C03	`09`	`X`	`FRE`	`@0 Virus immunodéficience humaine @2 NW @5 09`
C03	`09`	`X`	`ENG`	`@0 Human immunodeficiency virus @2 NW @5 09`
C03	`09`	`X`	`SPA`	`@0 Human immunodeficiency virus @2 NW @5 09`
C03	`10`	`X`	`FRE`	`@0 Enfant maltraité @5 10`
C03	`10`	`X`	`ENG`	`@0 Child abuse @5 10`
C03	`10`	`X`	`SPA`	`@0 Niño maltratado @5 10`
C03	`11`	`X`	`FRE`	`@0 Abus sexuel @5 11`
C03	`11`	`X`	`ENG`	`@0 Sexual abuse @5 11`
C03	`11`	`X`	`SPA`	`@0 Abuso sexual @5 11`
C03	`12`	`X`	`FRE`	`@0 Toxicomanie @5 12`
C03	`12`	`X`	`ENG`	`@0 Drug addiction @5 12`
C03	`12`	`X`	`SPA`	`@0 Toxicomanía @5 12`
C03	`13`	`X`	`FRE`	`@0 Abus de substance @2 NM @5 13`
C03	`13`	`X`	`ENG`	`@0 Substance abuse @2 NM @5 13`
C03	`13`	`X`	`SPA`	`@0 Abuso de sustancias @2 NM @5 13`
C03	`14`	`X`	`FRE`	`@0 Modèle équation structurale @5 14`
C03	`14`	`X`	`ENG`	`@0 Structural equation modeling @5 14`
C03	`14`	`X`	`SPA`	`@0 Modelo ecuación estructural @5 14`
C03	`15`	`X`	`FRE`	`@0 Santé publique @5 15`
C03	`15`	`X`	`ENG`	`@0 Public health @5 15`
C03	`15`	`X`	`SPA`	`@0 Salud pública @5 15`
C03	`16`	`X`	`FRE`	`@0 Santé mentale @5 16`
C03	`16`	`X`	`ENG`	`@0 Mental health @5 16`
C03	`16`	`X`	`SPA`	`@0 Salud mental @5 16`
C03	`17`	`X`	`FRE`	`@0 Environnement social @5 17`
C03	`17`	`X`	`ENG`	`@0 Social environment @5 17`
C03	`17`	`X`	`SPA`	`@0 Contexto social @5 17`
C03	`18`	`X`	`FRE`	`@0 Antiviral @5 31`
C03	`18`	`X`	`ENG`	`@0 Antiviral @5 31`
C03	`18`	`X`	`SPA`	`@0 Antiviral @5 31`
C03	`19`	`X`	`FRE`	`@0 Genre @4 CD @5 96`
C03	`19`	`X`	`ENG`	`@0 Gender @4 CD @5 96`
C03	`19`	`X`	`SPA`	`@0 Género @4 CD @5 96`
C07	`01`	`X`	`FRE`	`@0 Traitement`
C07	`01`	`X`	`ENG`	`@0 Treatment`
C07	`01`	`X`	`SPA`	`@0 Tratamiento`
C07	`02`	`X`	`FRE`	`@0 Virose`
C07	`02`	`X`	`ENG`	`@0 Viral disease`
C07	`02`	`X`	`SPA`	`@0 Virosis`
C07	`03`	`X`	`FRE`	`@0 Infection`
C07	`03`	`X`	`ENG`	`@0 Infection`
C07	`03`	`X`	`SPA`	`@0 Infección`
C07	`04`	`X`	`FRE`	`@0 Lentivirus @2 NW`
C07	`04`	`X`	`ENG`	`@0 Lentivirus @2 NW`
C07	`04`	`X`	`SPA`	`@0 Lentivirus @2 NW`
C07	`05`	`X`	`FRE`	`@0 Retroviridae @2 NW`
C07	`05`	`X`	`ENG`	`@0 Retroviridae @2 NW`
C07	`05`	`X`	`SPA`	`@0 Retroviridae @2 NW`
C07	`06`	`X`	`FRE`	`@0 Virus @2 NW`
C07	`06`	`X`	`ENG`	`@0 Virus @2 NW`
C07	`06`	`X`	`SPA`	`@0 Virus @2 NW`
C07	`07`	`X`	`FRE`	`@0 Immunodéficit @5 38`
C07	`07`	`X`	`ENG`	`@0 Immune deficiency @5 38`
C07	`07`	`X`	`SPA`	`@0 Inmunodeficiencia @5 38`
C07	`08`	`X`	`FRE`	`@0 Immunopathologie @5 40`
C07	`08`	`X`	`ENG`	`@0 Immunopathology @5 40`
C07	`08`	`X`	`SPA`	`@0 Inmunopatología @5 40`
C07	`09`	`X`	`FRE`	`@0 Victimologie @5 41`
C07	`09`	`X`	`ENG`	`@0 Victimology @5 41`
C07	`09`	`X`	`SPA`	`@0 Victimologia @5 41`
N21				`@1 216`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	FRANCIS 14-0175325 INIST
ET :	Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse
AU :	WILSON (Sarah M.); SIKKEMA (Kathleen J.); RANBY (Krista W.)
AF :	Department of Psychology and Neuroscience, Duke University/Durham, NC/Etats-Unis (1 aut., 2 aut.); Duke Global Health Institute/Durham, NC/Etats-Unis (1 aut., 2 aut.); Department of Psychology, University of Colorado Denver/Denver, CO/Etats-Unis (3 aut.)
DT :	Publication en série; Niveau analytique
SO :	AIDS Care : (Print); ISSN 0954-0121; Royaume-Uni; Da. 2014; Vol. 26; No. 7-8; Pp. 959-967; Bibl. 2 p.1/4
LA :	Anglais
EA :	This study aimed to examine gender moderation within a stress and coping model of HIV medication adherence in adults with a history of childhood sexual abuse (CSA). Sequelae of CSA, including negative coping, psychological distress, and drug use, interfere with adherence to highly active antiretroviral treatment (HAART). These obstacles to adherence are likely moderated by gender. Gender may particularly influence the mediational effect of drug use on adherence. Participants included 206 adults living with HIV/AIDS and CSA. Categorical/continuous variable methodology in a structural equation modeling framework was used to test a multigroup model with women and men. Gender significantly moderated several effects in the model. For women, the effect of psychological distress on HAART adherence was mediated by drug use and the effect of drug use on viral load was mediated by HAART adherence. Among men, drug use did not significantly impact adherence. Since gender appears to moderate the effect of drug use on medication adherence, it is particularly important to address drug use within the context of HIV disease management in women with a history of CSA. Further, interventions to increase HAART adherence should take trauma history, gender, and drug abuse into account when assessing efficacy.
CC :	770D06B; 770D03E01; 770D03E04
FD :	Sexe; Facteur psychosocial; Observance médicamenteuse; Pharmacothérapie; Association médicamenteuse; Antirétroviral; Contexte; SIDA; Virus immunodéficience humaine; Enfant maltraité; Abus sexuel; Toxicomanie; Abus de substance; Modèle équation structurale; Santé publique; Santé mentale; Environnement social; Antiviral; Genre
FG :	Traitement; Virose; Infection; Lentivirus; Retroviridae; Virus; Immunodéficit; Immunopathologie; Victimologie
ED :	Sex; Psychosocial factor; Drug compliance; Pharmacotherapy; Drug combination; Antiretroviral agent; Context; AIDS; Human immunodeficiency virus; Child abuse; Sexual abuse; Drug addiction; Substance abuse; Structural equation modeling; Public health; Mental health; Social environment; Antiviral; Gender
EG :	Treatment; Viral disease; Infection; Lentivirus; Retroviridae; Virus; Immune deficiency; Immunopathology; Victimology
SD :	Sexo; Factor sicosocial; Observancia de la medicación; Farmacoterapia; Asociación medicamentosa; Antiretroviral; Contexto; SIDA; Human immunodeficiency virus; Niño maltratado; Abuso sexual; Toxicomanía; Abuso de sustancias; Modelo ecuación estructural; Salud pública; Salud mental; Contexto social; Antiviral; Género
LO :	INIST-22096.354000502712540240
ID :	14-0175325

Links to Exploration step

Francis:14-0175325

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse</title>
<author><name sortKey="Wilson, Sarah M" sort="Wilson, Sarah M" uniqKey="Wilson S" first="Sarah M." last="Wilson">Sarah M. Wilson</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Psychology and Neuroscience, Duke University</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>Duke Global Health Institute</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Sikkema, Kathleen J" sort="Sikkema, Kathleen J" uniqKey="Sikkema K" first="Kathleen J." last="Sikkema">Kathleen J. Sikkema</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Psychology and Neuroscience, Duke University</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>Duke Global Health Institute</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Ranby, Krista W" sort="Ranby, Krista W" uniqKey="Ranby K" first="Krista W." last="Ranby">Krista W. Ranby</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Psychology, University of Colorado Denver</s1>
<s2>Denver, CO</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">14-0175325</idno>
<date when="2014">2014</date>
<idno type="stanalyst">FRANCIS 14-0175325 INIST</idno>
<idno type="RBID">Francis:14-0175325</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000013</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse</title>
<author><name sortKey="Wilson, Sarah M" sort="Wilson, Sarah M" uniqKey="Wilson S" first="Sarah M." last="Wilson">Sarah M. Wilson</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Psychology and Neuroscience, Duke University</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>Duke Global Health Institute</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Sikkema, Kathleen J" sort="Sikkema, Kathleen J" uniqKey="Sikkema K" first="Kathleen J." last="Sikkema">Kathleen J. Sikkema</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Psychology and Neuroscience, Duke University</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>Duke Global Health Institute</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Ranby, Krista W" sort="Ranby, Krista W" uniqKey="Ranby K" first="Krista W." last="Ranby">Krista W. Ranby</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Psychology, University of Colorado Denver</s1>
<s2>Denver, CO</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">AIDS Care : (Print)</title>
<title level="j" type="abbreviated">AIDS Care : (Print)</title>
<idno type="ISSN">0954-0121</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">AIDS Care : (Print)</title>
<title level="j" type="abbreviated">AIDS Care : (Print)</title>
<idno type="ISSN">0954-0121</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>AIDS</term>
<term>Antiretroviral agent</term>
<term>Antiviral</term>
<term>Child abuse</term>
<term>Context</term>
<term>Drug addiction</term>
<term>Drug combination</term>
<term>Drug compliance</term>
<term>Gender</term>
<term>Human immunodeficiency virus</term>
<term>Mental health</term>
<term>Pharmacotherapy</term>
<term>Psychosocial factor</term>
<term>Public health</term>
<term>Sex</term>
<term>Sexual abuse</term>
<term>Social environment</term>
<term>Structural equation modeling</term>
<term>Substance abuse</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Sexe</term>
<term>Facteur psychosocial</term>
<term>Observance médicamenteuse</term>
<term>Pharmacothérapie</term>
<term>Association médicamenteuse</term>
<term>Antirétroviral</term>
<term>Contexte</term>
<term>SIDA</term>
<term>Virus immunodéficience humaine</term>
<term>Enfant maltraité</term>
<term>Abus sexuel</term>
<term>Toxicomanie</term>
<term>Abus de substance</term>
<term>Modèle équation structurale</term>
<term>Santé publique</term>
<term>Santé mentale</term>
<term>Environnement social</term>
<term>Antiviral</term>
<term>Genre</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">This study aimed to examine gender moderation within a stress and coping model of HIV medication adherence in adults with a history of childhood sexual abuse (CSA). Sequelae of CSA, including negative coping, psychological distress, and drug use, interfere with adherence to highly active antiretroviral treatment (HAART). These obstacles to adherence are likely moderated by gender. Gender may particularly influence the mediational effect of drug use on adherence. Participants included 206 adults living with HIV/AIDS and CSA. Categorical/continuous variable methodology in a structural equation modeling framework was used to test a multigroup model with women and men. Gender significantly moderated several effects in the model. For women, the effect of psychological distress on HAART adherence was mediated by drug use and the effect of drug use on viral load was mediated by HAART adherence. Among men, drug use did not significantly impact adherence. Since gender appears to moderate the effect of drug use on medication adherence, it is particularly important to address drug use within the context of HIV disease management in women with a history of CSA. Further, interventions to increase HAART adherence should take trauma history, gender, and drug abuse into account when assessing efficacy.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0954-0121</s0>
</fA01>
<fA03 i2="1"><s0>AIDS Care : (Print)</s0>
</fA03>
<fA05><s2>26</s2>
</fA05>
<fA06><s2>7-8</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>WILSON (Sarah M.)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>SIKKEMA (Kathleen J.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>RANBY (Krista W.)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Psychology and Neuroscience, Duke University</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Duke Global Health Institute</s1>
<s2>Durham, NC</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Department of Psychology, University of Colorado Denver</s1>
<s2>Denver, CO</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA20><s1>959-967</s1>
</fA20>
<fA21><s1>2014</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>22096</s2>
<s5>354000502712540240</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2014 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>2 p.1/4</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>14-0175325</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>AIDS Care : (Print)</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>This study aimed to examine gender moderation within a stress and coping model of HIV medication adherence in adults with a history of childhood sexual abuse (CSA). Sequelae of CSA, including negative coping, psychological distress, and drug use, interfere with adherence to highly active antiretroviral treatment (HAART). These obstacles to adherence are likely moderated by gender. Gender may particularly influence the mediational effect of drug use on adherence. Participants included 206 adults living with HIV/AIDS and CSA. Categorical/continuous variable methodology in a structural equation modeling framework was used to test a multigroup model with women and men. Gender significantly moderated several effects in the model. For women, the effect of psychological distress on HAART adherence was mediated by drug use and the effect of drug use on viral load was mediated by HAART adherence. Among men, drug use did not significantly impact adherence. Since gender appears to moderate the effect of drug use on medication adherence, it is particularly important to address drug use within the context of HIV disease management in women with a history of CSA. Further, interventions to increase HAART adherence should take trauma history, gender, and drug abuse into account when assessing efficacy.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>770D06B</s0>
<s1>IV</s1>
</fC02>
<fC02 i1="02" i2="X"><s0>770D03E01</s0>
<s1>IV</s1>
</fC02>
<fC02 i1="03" i2="X"><s0>770D03E04</s0>
<s1>IV</s1>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Sexe</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Sex</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Sexo</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Facteur psychosocial</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Psychosocial factor</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Factor sicosocial</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Observance médicamenteuse</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Drug compliance</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Observancia de la medicación</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Pharmacothérapie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Pharmacotherapy</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Farmacoterapia</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Association médicamenteuse</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Drug combination</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Asociación medicamentosa</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Antirétroviral</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Antiretroviral agent</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Antiretroviral</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Contexte</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Context</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Contexto</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>SIDA</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>AIDS</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>SIDA</s0>
<s5>08</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Virus immunodéficience humaine</s0>
<s2>NW</s2>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Human immunodeficiency virus</s0>
<s2>NW</s2>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Human immunodeficiency virus</s0>
<s2>NW</s2>
<s5>09</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Enfant maltraité</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Child abuse</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Niño maltratado</s0>
<s5>10</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Abus sexuel</s0>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Sexual abuse</s0>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Abuso sexual</s0>
<s5>11</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Toxicomanie</s0>
<s5>12</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Drug addiction</s0>
<s5>12</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Toxicomanía</s0>
<s5>12</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>Abus de substance</s0>
<s2>NM</s2>
<s5>13</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG"><s0>Substance abuse</s0>
<s2>NM</s2>
<s5>13</s5>
</fC03>
<fC03 i1="13" i2="X" l="SPA"><s0>Abuso de sustancias</s0>
<s2>NM</s2>
<s5>13</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE"><s0>Modèle équation structurale</s0>
<s5>14</s5>
</fC03>
<fC03 i1="14" i2="X" l="ENG"><s0>Structural equation modeling</s0>
<s5>14</s5>
</fC03>
<fC03 i1="14" i2="X" l="SPA"><s0>Modelo ecuación estructural</s0>
<s5>14</s5>
</fC03>
<fC03 i1="15" i2="X" l="FRE"><s0>Santé publique</s0>
<s5>15</s5>
</fC03>
<fC03 i1="15" i2="X" l="ENG"><s0>Public health</s0>
<s5>15</s5>
</fC03>
<fC03 i1="15" i2="X" l="SPA"><s0>Salud pública</s0>
<s5>15</s5>
</fC03>
<fC03 i1="16" i2="X" l="FRE"><s0>Santé mentale</s0>
<s5>16</s5>
</fC03>
<fC03 i1="16" i2="X" l="ENG"><s0>Mental health</s0>
<s5>16</s5>
</fC03>
<fC03 i1="16" i2="X" l="SPA"><s0>Salud mental</s0>
<s5>16</s5>
</fC03>
<fC03 i1="17" i2="X" l="FRE"><s0>Environnement social</s0>
<s5>17</s5>
</fC03>
<fC03 i1="17" i2="X" l="ENG"><s0>Social environment</s0>
<s5>17</s5>
</fC03>
<fC03 i1="17" i2="X" l="SPA"><s0>Contexto social</s0>
<s5>17</s5>
</fC03>
<fC03 i1="18" i2="X" l="FRE"><s0>Antiviral</s0>
<s5>31</s5>
</fC03>
<fC03 i1="18" i2="X" l="ENG"><s0>Antiviral</s0>
<s5>31</s5>
</fC03>
<fC03 i1="18" i2="X" l="SPA"><s0>Antiviral</s0>
<s5>31</s5>
</fC03>
<fC03 i1="19" i2="X" l="FRE"><s0>Genre</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="19" i2="X" l="ENG"><s0>Gender</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="19" i2="X" l="SPA"><s0>Género</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Traitement</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Treatment</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Tratamiento</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Virose</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Viral disease</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Virosis</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Infection</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Lentivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Retroviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Immunodéficit</s0>
<s5>38</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Immune deficiency</s0>
<s5>38</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Inmunodeficiencia</s0>
<s5>38</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>40</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Victimologie</s0>
<s5>41</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Victimology</s0>
<s5>41</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Victimologia</s0>
<s5>41</s5>
</fC07>
<fN21><s1>216</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>FRANCIS 14-0175325 INIST</NO>
<ET>Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse</ET>
<AU>WILSON (Sarah M.); SIKKEMA (Kathleen J.); RANBY (Krista W.)</AU>
<AF>Department of Psychology and Neuroscience, Duke University/Durham, NC/Etats-Unis (1 aut., 2 aut.); Duke Global Health Institute/Durham, NC/Etats-Unis (1 aut., 2 aut.); Department of Psychology, University of Colorado Denver/Denver, CO/Etats-Unis (3 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>AIDS Care : (Print); ISSN 0954-0121; Royaume-Uni; Da. 2014; Vol. 26; No. 7-8; Pp. 959-967; Bibl. 2 p.1/4</SO>
<LA>Anglais</LA>
<EA>This study aimed to examine gender moderation within a stress and coping model of HIV medication adherence in adults with a history of childhood sexual abuse (CSA). Sequelae of CSA, including negative coping, psychological distress, and drug use, interfere with adherence to highly active antiretroviral treatment (HAART). These obstacles to adherence are likely moderated by gender. Gender may particularly influence the mediational effect of drug use on adherence. Participants included 206 adults living with HIV/AIDS and CSA. Categorical/continuous variable methodology in a structural equation modeling framework was used to test a multigroup model with women and men. Gender significantly moderated several effects in the model. For women, the effect of psychological distress on HAART adherence was mediated by drug use and the effect of drug use on viral load was mediated by HAART adherence. Among men, drug use did not significantly impact adherence. Since gender appears to moderate the effect of drug use on medication adherence, it is particularly important to address drug use within the context of HIV disease management in women with a history of CSA. Further, interventions to increase HAART adherence should take trauma history, gender, and drug abuse into account when assessing efficacy.</EA>
<CC>770D06B; 770D03E01; 770D03E04</CC>
<FD>Sexe; Facteur psychosocial; Observance médicamenteuse; Pharmacothérapie; Association médicamenteuse; Antirétroviral; Contexte; SIDA; Virus immunodéficience humaine; Enfant maltraité; Abus sexuel; Toxicomanie; Abus de substance; Modèle équation structurale; Santé publique; Santé mentale; Environnement social; Antiviral; Genre</FD>
<FG>Traitement; Virose; Infection; Lentivirus; Retroviridae; Virus; Immunodéficit; Immunopathologie; Victimologie</FG>
<ED>Sex; Psychosocial factor; Drug compliance; Pharmacotherapy; Drug combination; Antiretroviral agent; Context; AIDS; Human immunodeficiency virus; Child abuse; Sexual abuse; Drug addiction; Substance abuse; Structural equation modeling; Public health; Mental health; Social environment; Antiviral; Gender</ED>
<EG>Treatment; Viral disease; Infection; Lentivirus; Retroviridae; Virus; Immune deficiency; Immunopathology; Victimology</EG>
<SD>Sexo; Factor sicosocial; Observancia de la medicación; Farmacoterapia; Asociación medicamentosa; Antiretroviral; Contexto; SIDA; Human immunodeficiency virus; Niño maltratado; Abuso sexual; Toxicomanía; Abuso de sustancias; Modelo ecuación estructural; Salud pública; Salud mental; Contexto social; Antiviral; Género</SD>
<LO>INIST-22096.354000502712540240</LO>
<ID>14-0175325</ID>
</server>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/StressCovidV1/Data/PascalFrancis/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000013 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000013 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    StressCovidV1
   |flux=    PascalFrancis
   |étape=   Corpus
   |type=    RBID
   |clé=     Francis:14-0175325
   |texte=   Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed May 6 16:44:09 2020. Site generation: Sun Mar 28 08:26:57 2021

	Serveur d'exploration Stress et Covid
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Stress et Covid

Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse

Gender moderates the influence of psychosocial factors and drug use on HAART adherence in the context of HIV and childhood sexual abuse

Source :

Descripteurs français

English descriptors

Abstract

Notice en format standard (ISO 2709)

Format Inist (serveur)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri