StressCovidV1, Ncbi, Merge, bibRecord, 000F45

Elevated troponin in patients with Coronavirus Disease 2019 (COVID-19): possible mechanisms

Identifieur interne : 000F45 ( Ncbi/Merge ); précédent : 000F44; suivant : 000F46

Elevated troponin in patients with Coronavirus Disease 2019 (COVID-19): possible mechanisms

Auteurs : Gregorio Tersalvi [Suisse] ; Marco Vicenzi [Italie] ; Davide Calabretta [Italie] ; Luigi Biasco [Italie, Suisse] ; Giovanni Pedrazzini [Suisse] ; Dario Winterton [Italie]

Source :

Journal of Cardiac Failure [ 1071-9164 ] ; 2020.

RBID : PMC:7166030

Abstract

Coronavirus disease 2019 (COVID-19) is a pandemic that has affected more than 1.8 million people worldwide, overwhelmed health care systems due to the high proportion of critical presentations, and resulted in over 100,000 deaths. Since the first data analyses in China, elevated cardiac troponin has been noted in a substantial proportion of patients, implicating myocardial injury as a possible pathogenic mechanism contributing to severe illness and mortality. Accordingly, high troponin levels are associated with increased mortality in patients with COVID-19. This brief review explores the available evidence regarding the association between COVID-19 and myocardial injury.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166030

DOI: 10.1016/j.cardfail.2020.04.009
PubMed: 32315733
PubMed Central: 7166030

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PMC:7166030

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>Coronavirus disease 2019 (COVID-19) is a pandemic that has affected more than 1.8 million people worldwide, overwhelmed health care systems due to the high proportion of critical presentations, and resulted in over 100,000 deaths. Since the first data analyses in China, elevated cardiac troponin has been noted in a substantial proportion of patients, implicating myocardial injury as a possible pathogenic mechanism contributing to severe illness and mortality. Accordingly, high troponin levels are associated with increased mortality in patients with COVID-19. This brief review explores the available evidence regarding the association between COVID-19 and myocardial injury.</p>
</div>
</front>
</TEI>
<pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
  <front><journal-meta><journal-id journal-id-type="nlm-ta">J Card Fail</journal-id>
<journal-id journal-id-type="iso-abbrev">J. Card. Fail</journal-id>
<journal-title-group><journal-title>Journal of Cardiac Failure</journal-title>
</journal-title-group>
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<article-id pub-id-type="doi">10.1016/j.cardfail.2020.04.009</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
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</article-categories>
<title-group><article-title>Elevated troponin in patients with Coronavirus Disease 2019 (COVID-19): possible mechanisms</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" id="au0001"><name><surname>Tersalvi</surname>
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<email>tersalvi@gmail.com</email>
<xref rid="aff0001" ref-type="aff">1</xref>
<xref rid="aff0002" ref-type="aff">2</xref>
<xref rid="cor0001" ref-type="corresp">⁎</xref>
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<contrib contrib-type="author" id="au0002"><name><surname>Vicenzi</surname>
<given-names>Marco</given-names>
</name>
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<xref rid="aff0004" ref-type="aff">4</xref>
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<contrib contrib-type="author" id="au0003"><name><surname>Calabretta</surname>
<given-names>Davide</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff0005" ref-type="aff">5</xref>
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<contrib contrib-type="author" id="au0004"><name><surname>Biasco</surname>
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<xref rid="aff0006" ref-type="aff">6</xref>
<xref rid="aff0007" ref-type="aff">7</xref>
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<given-names>Giovanni</given-names>
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<contrib contrib-type="author" id="au0006"><name><surname>Winterton</surname>
<given-names>Dario</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff0008" ref-type="aff">8</xref>
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</contrib-group>
<aff id="aff0001"><label>1</label>
Division of Cardiology, Fondazione Cardiocentro Ticino, Lugano, Switzerland</aff>
<aff id="aff0002"><label>2</label>
Department of Internal Medicine, Hirslanden Klinik St. Anna, Lucerne, Switzerland</aff>
<aff id="aff0003"><label>3</label>
Cardiovascular Disease Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy</aff>
<aff id="aff0004"><label>4</label>
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy</aff>
<aff id="aff0005"><label>5</label>
Department of Anesthesia and Intensive Care Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy</aff>
<aff id="aff0006"><label>6</label>
Division of Cardiology, Azienda Sanitaria Locale Torino 4, Ospedale di Ciriè, Ciriè, Italy</aff>
<aff id="aff0007"><label>7</label>
Department of Biomedical Sciences, University of Italian Switzerland, Lugano, Switzerland</aff>
<aff id="aff0008"><label>8</label>
Department of Anesthesia and Intensive Care Medicine, ASST Monza, Monza, Italy</aff>
<author-notes><corresp id="cor0001"><label>⁎</label>
Corresponding author. Gregorio Tersalvi, MD, Hirslanden Klinik St. Anna, Sankt-Anna-Strasse 32, 6006 Lucerne, Switzerland. <email>tersalvi@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="pmc-release"><day>18</day>
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<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
      <pub-date pub-type="epub"><day>18</day>
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<year>2020</year>
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<date date-type="rev-recd"><day>14</day>
<month>4</month>
<year>2020</year>
</date>
<date date-type="accepted"><day>15</day>
<month>4</month>
<year>2020</year>
</date>
</history>
<permissions><copyright-statement>© 2020 Elsevier Inc. All rights reserved.</copyright-statement>
<copyright-year>2020</copyright-year>
<copyright-holder></copyright-holder>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<abstract id="abs0001"><p>Coronavirus disease 2019 (COVID-19) is a pandemic that has affected more than 1.8 million people worldwide, overwhelmed health care systems due to the high proportion of critical presentations, and resulted in over 100,000 deaths. Since the first data analyses in China, elevated cardiac troponin has been noted in a substantial proportion of patients, implicating myocardial injury as a possible pathogenic mechanism contributing to severe illness and mortality. Accordingly, high troponin levels are associated with increased mortality in patients with COVID-19. This brief review explores the available evidence regarding the association between COVID-19 and myocardial injury.</p>
</abstract>
<kwd-group id="keys0001"><title>Keywords</title>
<kwd>COVID-19</kwd>
<kwd>coronavirus</kwd>
<kwd>SARS</kwd>
<kwd>troponin</kwd>
<kwd>myocardial injury</kwd>
<kwd>myocarditis</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
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<tree><country name="Suisse"><noRegion><name sortKey="Tersalvi, Gregorio" sort="Tersalvi, Gregorio" uniqKey="Tersalvi G" first="Gregorio" last="Tersalvi">Gregorio Tersalvi</name>
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<name sortKey="Biasco, Luigi" sort="Biasco, Luigi" uniqKey="Biasco L" first="Luigi" last="Biasco">Luigi Biasco</name>
<name sortKey="Pedrazzini, Giovanni" sort="Pedrazzini, Giovanni" uniqKey="Pedrazzini G" first="Giovanni" last="Pedrazzini">Giovanni Pedrazzini</name>
<name sortKey="Pedrazzini, Giovanni" sort="Pedrazzini, Giovanni" uniqKey="Pedrazzini G" first="Giovanni" last="Pedrazzini">Giovanni Pedrazzini</name>
<name sortKey="Tersalvi, Gregorio" sort="Tersalvi, Gregorio" uniqKey="Tersalvi G" first="Gregorio" last="Tersalvi">Gregorio Tersalvi</name>
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<country name="Italie"><region name="Lombardie"><name sortKey="Vicenzi, Marco" sort="Vicenzi, Marco" uniqKey="Vicenzi M" first="Marco" last="Vicenzi">Marco Vicenzi</name>
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<name sortKey="Vicenzi, Marco" sort="Vicenzi, Marco" uniqKey="Vicenzi M" first="Marco" last="Vicenzi">Marco Vicenzi</name>
<name sortKey="Winterton, Dario" sort="Winterton, Dario" uniqKey="Winterton D" first="Dario" last="Winterton">Dario Winterton</name>
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Elevated troponin in patients with Coronavirus Disease 2019 (COVID-19): possible mechanisms

Elevated troponin in patients with Coronavirus Disease 2019 (COVID-19): possible mechanisms

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Abstract

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