Loneliness, social network size, and immune response to influenza vaccination in college freshmen.
Identifieur interne : 000156 ( Ncbi/Merge ); précédent : 000155; suivant : 000157Loneliness, social network size, and immune response to influenza vaccination in college freshmen.
Auteurs : Sarah D. Pressman [États-Unis] ; Sheldon Cohen ; Gregory E. Miller ; Anita Barkin ; Bruce S. Rabin ; John J. TreanorSource :
- Health psychology : official journal of the Division of Health Psychology, American Psychological Association [ 0278-6133 ] ; 2005.
Descripteurs français
- KwdFr :
- MESH :
- biosynthèse : Anticorps antiviraux.
- immunologie : Anticorps antiviraux, Vaccins antigrippaux.
- Adolescent, Adulte, Femelle, Humains, Mâle, Pennsylvanie, Solitude, Sommeil, Soutien social, Stress psychologique, Universités, Étudiants.
English descriptors
- KwdEn :
- MESH :
- chemical , biosynthesis : Antibodies, Viral.
- chemical , immunology : Antibodies, Viral, Influenza Vaccines.
- geographic : Pennsylvania.
- Adolescent, Adult, Female, Humans, Loneliness, Male, Sleep, Social Support, Stress, Psychological, Students, Universities.
Abstract
Antibody response to the influenza immunization was investigated in 83 1st-semester healthy university freshmen. Elevated levels of loneliness throughout the semester and small social networks were independently associated with poorer antibody response to 1 component of the vaccine. Those with both high levels of loneliness and a small social network had the lowest antibody response. Loneliness was also associated with greater psychological stress and negative affect, less positive affect, poorer sleep efficiency and quality, and elevations in circulating levels of cortisol. However, only the stress data were consistent with mediation of the loneliness-antibody response relation. None of these variables were associated with social network size, and hence none were potential mediators of the relation between network size and immunization response.
DOI: 10.1037/0278-6133.24.3.297
PubMed: 15898866
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pubmed:15898866Le document en format XML
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<term>Female</term>
<term>Humans</term>
<term>Influenza Vaccines (immunology)</term>
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<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Pennsylvanie</term>
<term>Solitude</term>
<term>Sommeil</term>
<term>Soutien social</term>
<term>Stress psychologique</term>
<term>Universités</term>
<term>Vaccins antigrippaux (immunologie)</term>
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<front><div type="abstract" xml:lang="en">Antibody response to the influenza immunization was investigated in 83 1st-semester healthy university freshmen. Elevated levels of loneliness throughout the semester and small social networks were independently associated with poorer antibody response to 1 component of the vaccine. Those with both high levels of loneliness and a small social network had the lowest antibody response. Loneliness was also associated with greater psychological stress and negative affect, less positive affect, poorer sleep efficiency and quality, and elevations in circulating levels of cortisol. However, only the stress data were consistent with mediation of the loneliness-antibody response relation. None of these variables were associated with social network size, and hence none were potential mediators of the relation between network size and immunization response.</div>
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