Considerations about the possible function of ceruloplasmin in influenza and parainfluenza virus infections.
Identifieur interne : 000973 ( Ncbi/Checkpoint ); précédent : 000972; suivant : 000974Considerations about the possible function of ceruloplasmin in influenza and parainfluenza virus infections.
Auteurs : E. Tomas ; F. TopârceanuSource :
- Virologie [ 0253-181X ]
Descripteurs français
- KwdFr :
- Animaux, Antigènes viraux (immunologie), Céruloplasmine (métabolisme), Infections à Orthomyxoviridae (enzymologie), Infections à Paramyxoviridae (enzymologie), Orthomyxoviridae (physiologie), Relation structure-activité, Respirovirus (physiologie), Réplication virale (), Stress physiologique (enzymologie), Érythrocytes (enzymologie).
- MESH :
- enzymologie : Infections à Orthomyxoviridae, Infections à Paramyxoviridae, Stress physiologique, Érythrocytes.
- immunologie : Antigènes viraux.
- métabolisme : Céruloplasmine.
- physiologie : Orthomyxoviridae, Respirovirus.
- Animaux, Relation structure-activité, Réplication virale.
English descriptors
- KwdEn :
- Animals, Antigens, Viral (immunology), Ceruloplasmin (metabolism), Erythrocytes (enzymology), Orthomyxoviridae (physiology), Orthomyxoviridae Infections (enzymology), Paramyxoviridae Infections (enzymology), Respirovirus (physiology), Stress, Physiological (enzymology), Structure-Activity Relationship, Virus Replication (drug effects).
- MESH :
- chemical , immunology : Antigens, Viral.
- chemical , metabolism : Ceruloplasmin.
- drug effects : Virus Replication.
- enzymology : Erythrocytes, Orthomyxoviridae Infections, Paramyxoviridae Infections, Stress, Physiological.
- physiology : Orthomyxoviridae, Respirovirus.
- Animals, Structure-Activity Relationship.
Abstract
The experimental data reveal that ceruloplasmin is a serum nonspecific factor acting during the early and late stages of infection with some respiratory viruses. This complex action seems to be based both on the enzymatic activity and on the copper-glycoprotein structure of ceruloplasmin. The changes in progen antigenicity produced by ceruloplasmin are probably involved in the mechanism of the antigenic shift and drift.
PubMed: 3029949
Affiliations:
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pubmed:3029949Le document en format XML
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<term>Antigens, Viral (immunology)</term>
<term>Ceruloplasmin (metabolism)</term>
<term>Erythrocytes (enzymology)</term>
<term>Orthomyxoviridae (physiology)</term>
<term>Orthomyxoviridae Infections (enzymology)</term>
<term>Paramyxoviridae Infections (enzymology)</term>
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<term>Structure-Activity Relationship</term>
<term>Virus Replication (drug effects)</term>
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<term>Antigènes viraux (immunologie)</term>
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<term>Infections à Orthomyxoviridae (enzymologie)</term>
<term>Infections à Paramyxoviridae (enzymologie)</term>
<term>Orthomyxoviridae (physiologie)</term>
<term>Relation structure-activité</term>
<term>Respirovirus (physiologie)</term>
<term>Réplication virale ()</term>
<term>Stress physiologique (enzymologie)</term>
<term>Érythrocytes (enzymologie)</term>
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<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antigens, Viral</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Ceruloplasmin</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Virus Replication</term>
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<keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Infections à Orthomyxoviridae</term>
<term>Infections à Paramyxoviridae</term>
<term>Stress physiologique</term>
<term>Érythrocytes</term>
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<keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Erythrocytes</term>
<term>Orthomyxoviridae Infections</term>
<term>Paramyxoviridae Infections</term>
<term>Stress, Physiological</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes viraux</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Céruloplasmine</term>
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<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Orthomyxoviridae</term>
<term>Respirovirus</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Orthomyxoviridae</term>
<term>Respirovirus</term>
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<term>Structure-Activity Relationship</term>
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<front><div type="abstract" xml:lang="en">The experimental data reveal that ceruloplasmin is a serum nonspecific factor acting during the early and late stages of infection with some respiratory viruses. This complex action seems to be based both on the enzymatic activity and on the copper-glycoprotein structure of ceruloplasmin. The changes in progen antigenicity produced by ceruloplasmin are probably involved in the mechanism of the antigenic shift and drift.</div>
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<name sortKey="Toparceanu, F" sort="Toparceanu, F" uniqKey="Toparceanu F" first="F" last="Topârceanu">F. Topârceanu</name>
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