StressCovidV1, Main, Exploration, bibRecord, 003804

Immunodeficiency in the chicken. I. Disparity in suppression of antibody responses to various antigens following surgical bursectomy.

Identifieur interne : 003804 ( Main/Exploration ); précédent : 003803; suivant : 003805

Immunodeficiency in the chicken. I. Disparity in suppression of antibody responses to various antigens following surgical bursectomy.

Auteurs : J. Ivanyi

Source :

Immunology [ 0019-2805 ] ; 1975.

RBID : pubmed:166036

Descripteurs français

KwdFr :
- Animaux, Antigènes bactériens, Antigènes viraux, Bordetella pertussis (immunologie), Bourse de Fabricius (immunologie), Facteurs de l'âge, Humains, Immunisation, Immunosuppression thérapeutique, Orthomyxoviridae (immunologie), Ovis (immunologie), Poulets, Production d'anticorps, Sérumalbumine (immunologie), Érythrocytes (immunologie).
MESH :
- immunologie : Bordetella pertussis, Bourse de Fabricius, Orthomyxoviridae, Ovis, Sérumalbumine, Érythrocytes.
- Animaux, Antigènes bactériens, Antigènes viraux, Facteurs de l'âge, Humains, Immunisation, Immunosuppression thérapeutique, Poulets, Production d'anticorps.

English descriptors

KwdEn :
- Age Factors, Animals, Antibody Formation, Antigens, Bacterial, Antigens, Viral, Bordetella pertussis (immunology), Bursa of Fabricius (immunology), Chickens, Erythrocytes (immunology), Humans, Immunization, Immunosuppression, Orthomyxoviridae (immunology), Serum Albumin (immunology), Sheep (immunology).
MESH :
- chemical , immunology : Serum Albumin.
- chemical : Antigens, Bacterial, Antigens, Viral.
- immunology : Bordetella pertussis, Bursa of Fabricius, Erythrocytes, Orthomyxoviridae, Sheep.
- Age Factors, Animals, Antibody Formation, Chickens, Humans, Immunization, Immunosuppression.

Abstract

The extent of suppression of antibody response by bursectomy (Bx) was examined as a measure of the seeding sequence of different clones from the bursa to peripheral lymphoid tissues. Chickens were bursectomized surgically 1, 4 or 7 days after hatching and immunized later with four antigens: sheep red blood cells (SRBC); Bordetella pertussis (Bp); human serum albumin (HSA); influenza virus (IV). The kinetics of the antibody responses were delayed in bursectomized birds when compared with the control groups. The following order in the degree of immunosuppression was established: Bp greater than HSA greater than SRBC greater than IV. This is discussed in relation to the 'sequential maturation' theory of ontogenesis of immunocyte differentiation. The data also stress the limitation of non-specific markers for assessing partial immunodeficiency states.

PubMed: 166036

Affiliations:

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<term>Immunosuppression thérapeutique</term>
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<term>Production d'anticorps</term>
<term>Sérumalbumine (immunologie)</term>
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<term>Sheep</term>
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<term>Animals</term>
<term>Antibody Formation</term>
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<term>Humans</term>
<term>Immunization</term>
<term>Immunosuppression</term>
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<term>Antigènes bactériens</term>
<term>Antigènes viraux</term>
<term>Facteurs de l'âge</term>
<term>Humains</term>
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<front><div type="abstract" xml:lang="en">The extent of suppression of antibody response by bursectomy (Bx) was examined as a measure of the seeding sequence of different clones from the bursa to peripheral lymphoid tissues. Chickens were bursectomized surgically 1, 4 or 7 days after hatching and immunized later with four antigens: sheep red blood cells (SRBC); Bordetella pertussis (Bp); human serum albumin (HSA); influenza virus (IV). The kinetics of the antibody responses were delayed in bursectomized birds when compared with the control groups. The following order in the degree of immunosuppression was established: Bp greater than HSA greater than SRBC greater than IV. This is discussed in relation to the 'sequential maturation' theory of ontogenesis of immunocyte differentiation. The data also stress the limitation of non-specific markers for assessing partial immunodeficiency states.</div>
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Immunodeficiency in the chicken. I. Disparity in suppression of antibody responses to various antigens following surgical bursectomy.

Immunodeficiency in the chicken. I. Disparity in suppression of antibody responses to various antigens following surgical bursectomy.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration Stress et Covid
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