An investigation of the immune response of patients suffering from anorexia nervosa.
Identifieur interne : 003793 ( Main/Exploration ); précédent : 003792; suivant : 003794An investigation of the immune response of patients suffering from anorexia nervosa.
Auteurs : C. A. Armstrong-Esther ; J. H. Lacey ; A. H. Crisp ; T. N. BryantSource :
- Postgraduate Medical Journal [ 0032-5473 ] ; 1978-06.
English descriptors
- Teeft :
- Academic press, Admune influenza vaccine, Animal experiments, Anorectic, Anorexia, Anorexia nervosa, Body weight, Carbohydrate, Clinical findings, Control group, Control population, Haemagglutination, Haemagglutination inhibition tests, Higher titres, Hong kong, Immune response, Immunological response, Influenza, Influenza antigens, Kwashiorkor, Macrophage inhibition test, Marasmic infants, Menstrual cycle, Nervosa, Nicol, Normal levels, Oestrogen, Possible relationship, Protein depletion, Reproductive hormones, Serum levels, Significant difference, Standard deviation, Survival time, Test group, Titre, Tuberculin test, Venous blood.
Abstract
Patients suffering from anorexia nervosa rarely appear to develop the common cold or influenza. This study examines the immunological response of fifteen female anorexia nervosa patients of both the vomiting and carbohydrate-abstaining type and compares them with a control population matched for age and occupation. Both anorectics and control populations received the admune influenza vaccine. Initially both groups had similar haemagglutination inhibition titres against the three different viral antigens: A/HK; A/PC; A/Eng. However, the anorectics showed over a 2-month period a higher titre of antibody especially to the Hong Kong virus: this was sigignificant. Cellular immune responses were measured using a tuberculin and a macrophage inhibition test, no significant difference between the two groups was obderved. These results which support the clinical findings are discussed.
Url:
DOI: 10.1136/pgmj.54.632.395
Affiliations:
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- to stream Main, to step Curation: 003793
Le document en format XML
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<front><div type="abstract" xml:lang="en">Patients suffering from anorexia nervosa rarely appear to develop the common cold or influenza. This study examines the immunological response of fifteen female anorexia nervosa patients of both the vomiting and carbohydrate-abstaining type and compares them with a control population matched for age and occupation. Both anorectics and control populations received the admune influenza vaccine. Initially both groups had similar haemagglutination inhibition titres against the three different viral antigens: A/HK; A/PC; A/Eng. However, the anorectics showed over a 2-month period a higher titre of antibody especially to the Hong Kong virus: this was sigignificant. Cellular immune responses were measured using a tuberculin and a macrophage inhibition test, no significant difference between the two groups was obderved. These results which support the clinical findings are discussed.</div>
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<name sortKey="Crisp, A H" sort="Crisp, A H" uniqKey="Crisp A" first="A. H." last="Crisp">A. H. Crisp</name>
<name sortKey="Lacey, J H" sort="Lacey, J H" uniqKey="Lacey J" first="J. H." last="Lacey">J. H. Lacey</name>
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