[Epidemiological actualization of the avian influenza. New analysis of sanitary risk].
Identifieur interne : 001A43 ( Main/Curation ); précédent : 001A42; suivant : 001A44[Epidemiological actualization of the avian influenza. New analysis of sanitary risk].
Auteurs : Guillermo Suárez FernándezSource :
- Anales de la Real Academia Nacional de Medicina [ 0034-0634 ] ; 2009.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Sous-type H5N1 du virus de la grippe A.
- virologie : Grippe chez les oiseaux, Grippe humaine.
- épidémiologie : Grippe chez les oiseaux, Grippe humaine.
- Animaux, Humains, Oiseaux, Prévision, Évaluation des risques.
English descriptors
- KwdEn :
- MESH :
- epidemiology : Influenza in Birds, Influenza, Human.
- genetics : Influenza A Virus, H5N1 Subtype.
- virology : Influenza in Birds, Influenza, Human.
- Animals, Birds, Forecasting, Humans, Risk Assessment.
Abstract
A review has been made of the present epidemics of Avian Influenza, which originated in the year 2003 in Southeast Asia, and expanded thereafter to 60 countries in three continents (Asia, Africa and Europe), with more than 3000 outbreaks and millions of affected poultry, and 80% mortality. Special emphasis is made on the genetic variability of the etiological agent, the Orthomyxovirus A H5N1, which may accumulate point mutations in several genes distributed in eight segments, and especially in the gene which encodes the hemagglutinin (HA). Stress is made in a recent mutation in the gene which encodes polymerase PB2, which determines the substitution of one amino acid, and is associated to the virulence of the virion, enabling it to adapt to the upper human respiratory tract and to replicate in this area. This mutation dangerously approaches the virus A H5N1 to a possible interhuman transmission and to become a pandemic virus, possibly in the near future. The present knowledge and the social structure would permit to content and control the pandemic state with the due speed and efficacy.
PubMed: 20432671
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000759
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000756
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000705
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000373
- to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :000373
- to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000373
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :001A45
Links to Exploration step
pubmed:20432671Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Epidemiological actualization of the avian influenza. New analysis of sanitary risk].</title>
<author><name sortKey="Suarez Fernandez, Guillermo" sort="Suarez Fernandez, Guillermo" uniqKey="Suarez Fernandez G" first="Guillermo" last="Suárez Fernández">Guillermo Suárez Fernández</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2009">2009</date>
<idno type="RBID">pubmed:20432671</idno>
<idno type="pmid">20432671</idno>
<idno type="wicri:Area/PubMed/Corpus">000759</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000759</idno>
<idno type="wicri:Area/PubMed/Curation">000756</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000756</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000705</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000705</idno>
<idno type="wicri:Area/Ncbi/Merge">000373</idno>
<idno type="wicri:Area/Ncbi/Curation">000373</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000373</idno>
<idno type="wicri:doubleKey">0034-0634:2009:Suarez Fernandez G:epidemiological:actualization:of</idno>
<idno type="wicri:Area/Main/Merge">001A45</idno>
<idno type="wicri:Area/Main/Curation">001A43</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">[Epidemiological actualization of the avian influenza. New analysis of sanitary risk].</title>
<author><name sortKey="Suarez Fernandez, Guillermo" sort="Suarez Fernandez, Guillermo" uniqKey="Suarez Fernandez G" first="Guillermo" last="Suárez Fernández">Guillermo Suárez Fernández</name>
</author>
</analytic>
<series><title level="j">Anales de la Real Academia Nacional de Medicina</title>
<idno type="ISSN">0034-0634</idno>
<imprint><date when="2009" type="published">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Birds</term>
<term>Forecasting</term>
<term>Humans</term>
<term>Influenza A Virus, H5N1 Subtype (genetics)</term>
<term>Influenza in Birds (epidemiology)</term>
<term>Influenza in Birds (virology)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (virology)</term>
<term>Risk Assessment</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Grippe chez les oiseaux (virologie)</term>
<term>Grippe chez les oiseaux (épidémiologie)</term>
<term>Grippe humaine (virologie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Humains</term>
<term>Oiseaux</term>
<term>Prévision</term>
<term>Sous-type H5N1 du virus de la grippe A (génétique)</term>
<term>Évaluation des risques</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza in Birds</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A Virus, H5N1 Subtype</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Sous-type H5N1 du virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe chez les oiseaux</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza in Birds</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Grippe chez les oiseaux</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Birds</term>
<term>Forecasting</term>
<term>Humans</term>
<term>Risk Assessment</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Humains</term>
<term>Oiseaux</term>
<term>Prévision</term>
<term>Évaluation des risques</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">A review has been made of the present epidemics of Avian Influenza, which originated in the year 2003 in Southeast Asia, and expanded thereafter to 60 countries in three continents (Asia, Africa and Europe), with more than 3000 outbreaks and millions of affected poultry, and 80% mortality. Special emphasis is made on the genetic variability of the etiological agent, the Orthomyxovirus A H5N1, which may accumulate point mutations in several genes distributed in eight segments, and especially in the gene which encodes the hemagglutinin (HA). Stress is made in a recent mutation in the gene which encodes polymerase PB2, which determines the substitution of one amino acid, and is associated to the virulence of the virion, enabling it to adapt to the upper human respiratory tract and to replicate in this area. This mutation dangerously approaches the virus A H5N1 to a possible interhuman transmission and to become a pandemic virus, possibly in the near future. The present knowledge and the social structure would permit to content and control the pandemic state with the due speed and efficacy.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/StressCovidV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001A43 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 001A43 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= StressCovidV1 |flux= Main |étape= Curation |type= RBID |clé= pubmed:20432671 |texte= [Epidemiological actualization of the avian influenza. New analysis of sanitary risk]. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Curation/RBID.i -Sk "pubmed:20432671" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Curation/biblio.hfd \ | NlmPubMed2Wicri -a StressCovidV1
This area was generated with Dilib version V0.6.33. |