Approach to a Child with Acute Flaccid Paralysis
Identifieur interne : 000C23 ( Istex/Corpus ); précédent : 000C22; suivant : 000C24Approach to a Child with Acute Flaccid Paralysis
Auteurs : Sunit C. Singhi ; Naveen Sankhyan ; Ravi Shah ; Pratibha SinghiSource :
- The Indian Journal of Pediatrics [ 0019-5456 ] ; 2012-10-01.
English descriptors
Abstract
Abstract: Acute flaccid paralysis (AFP) is a clinical syndrome characterized by rapid onset weakness, that many times includes respiratory and bulbar weakness. AFP is a broad clinical entity with an array of diagnostic possibilities. An accurate and early diagnosis of the cause has important bearing on the management and prognosis. The immediate priorities in a child who presents with acute progressive weakness are; to detect and manage respiratory muscle weakness, to detect and manage bulbar weakness, evaluate for cardiovascular instability, detect and manage dyselectrolytemia or toxemia, and to detect and manage a spinal compression (traumatic, intraspinal collections). Urgent imaging of the spine is needed in settings where a spinal cord involvement is suspected. Compressive or traumatic spinal lesions may need early neurosurgical intervention. Anterior horn cell injury is usually due to direct viral infection. More distal pathologies are generally immune mediated and respond to immunomodulation. Irrespective of the cause, generalized weakness frequently affects respiratory and bulbar function. Such children need careful monitoring and respiratory support.
Url:
DOI: 10.1007/s12098-012-0831-8
Links to Exploration step
ISTEX:C3A2F03BDAE1BCCBCF6AE7782E13C5B0867AB415Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Approach to a Child with Acute Flaccid Paralysis</title><author><name sortKey="Singhi, Sunit C" sort="Singhi, Sunit C" uniqKey="Singhi S" first="Sunit C." last="Singhi">Sunit C. Singhi</name><affiliation><mods:affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: sunit.singhi@gmail.com</mods:affiliation></affiliation></author><author><name sortKey="Sankhyan, Naveen" sort="Sankhyan, Naveen" uniqKey="Sankhyan N" first="Naveen" last="Sankhyan">Naveen Sankhyan</name><affiliation><mods:affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</mods:affiliation></affiliation></author><author><name sortKey="Shah, Ravi" sort="Shah, Ravi" uniqKey="Shah R" first="Ravi" last="Shah">Ravi Shah</name><affiliation><mods:affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</mods:affiliation></affiliation></author><author><name sortKey="Singhi, Pratibha" sort="Singhi, Pratibha" uniqKey="Singhi P" first="Pratibha" last="Singhi">Pratibha Singhi</name><affiliation><mods:affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:C3A2F03BDAE1BCCBCF6AE7782E13C5B0867AB415</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1007/s12098-012-0831-8</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-070SB7BN-6/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000C23</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000C23</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Approach to a Child with Acute Flaccid Paralysis</title><author><name sortKey="Singhi, Sunit C" sort="Singhi, Sunit C" uniqKey="Singhi S" first="Sunit C." last="Singhi">Sunit C. Singhi</name><affiliation><mods:affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: sunit.singhi@gmail.com</mods:affiliation></affiliation></author><author><name sortKey="Sankhyan, Naveen" sort="Sankhyan, Naveen" uniqKey="Sankhyan N" first="Naveen" last="Sankhyan">Naveen Sankhyan</name><affiliation><mods:affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</mods:affiliation></affiliation></author><author><name sortKey="Shah, Ravi" sort="Shah, Ravi" uniqKey="Shah R" first="Ravi" last="Shah">Ravi Shah</name><affiliation><mods:affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</mods:affiliation></affiliation></author><author><name sortKey="Singhi, Pratibha" sort="Singhi, Pratibha" uniqKey="Singhi P" first="Pratibha" last="Singhi">Pratibha Singhi</name><affiliation><mods:affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">The Indian Journal of Pediatrics</title><title level="j" type="abbrev">Indian J Pediatr</title><idno type="ISSN">0019-5456</idno><idno type="eISSN">0973-7693</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>India</pubPlace><date type="published" when="2012-10-01">2012-10-01</date><biblScope unit="volume">79</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1351">1351</biblScope><biblScope unit="page" to="1357">1357</biblScope></imprint><idno type="ISSN">0019-5456</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0019-5456</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute weakness</term><term>Guillain Barre syndrome</term><term>Paraparesis</term><term>Polio</term><term>Transverse myelitis</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Acute flaccid paralysis (AFP) is a clinical syndrome characterized by rapid onset weakness, that many times includes respiratory and bulbar weakness. AFP is a broad clinical entity with an array of diagnostic possibilities. An accurate and early diagnosis of the cause has important bearing on the management and prognosis. The immediate priorities in a child who presents with acute progressive weakness are; to detect and manage respiratory muscle weakness, to detect and manage bulbar weakness, evaluate for cardiovascular instability, detect and manage dyselectrolytemia or toxemia, and to detect and manage a spinal compression (traumatic, intraspinal collections). Urgent imaging of the spine is needed in settings where a spinal cord involvement is suspected. Compressive or traumatic spinal lesions may need early neurosurgical intervention. Anterior horn cell injury is usually due to direct viral infection. More distal pathologies are generally immune mediated and respond to immunomodulation. Irrespective of the cause, generalized weakness frequently affects respiratory and bulbar function. Such children need careful monitoring and respiratory support.</div></front></TEI><istex><corpusName>springer-journals</corpusName><author><json:item><name>Sunit C. Singhi</name><affiliations><json:string>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</json:string><json:string>E-mail: sunit.singhi@gmail.com</json:string></affiliations></json:item><json:item><name>Naveen Sankhyan</name><affiliations><json:string>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</json:string></affiliations></json:item><json:item><name>Ravi Shah</name><affiliations><json:string>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</json:string></affiliations></json:item><json:item><name>Pratibha Singhi</name><affiliations><json:string>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Polio</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Acute weakness</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Paraparesis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Transverse myelitis</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Guillain Barre syndrome</value></json:item></subject><articleId><json:string>831</json:string><json:string>s12098-012-0831-8</json:string></articleId><arkIstex>ark:/67375/VQC-070SB7BN-6</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>ReviewPaper</json:string></originalGenre><abstract>Abstract: Acute flaccid paralysis (AFP) is a clinical syndrome characterized by rapid onset weakness, that many times includes respiratory and bulbar weakness. AFP is a broad clinical entity with an array of diagnostic possibilities. An accurate and early diagnosis of the cause has important bearing on the management and prognosis. The immediate priorities in a child who presents with acute progressive weakness are; to detect and manage respiratory muscle weakness, to detect and manage bulbar weakness, evaluate for cardiovascular instability, detect and manage dyselectrolytemia or toxemia, and to detect and manage a spinal compression (traumatic, intraspinal collections). Urgent imaging of the spine is needed in settings where a spinal cord involvement is suspected. Compressive or traumatic spinal lesions may need early neurosurgical intervention. Anterior horn cell injury is usually due to direct viral infection. More distal pathologies are generally immune mediated and respond to immunomodulation. Irrespective of the cause, generalized weakness frequently affects respiratory and bulbar function. Such children need careful monitoring and respiratory support.</abstract><qualityIndicators><refBibsNative>false</refBibsNative><abstractWordCount>165</abstractWordCount><abstractCharCount>1177</abstractCharCount><keywordCount>5</keywordCount><score>7.248</score><pdfWordCount>3268</pdfWordCount><pdfCharCount>24150</pdfCharCount><pdfVersion>1.4</pdfVersion><pdfPageCount>7</pdfPageCount><pdfPageSize>595.276 x 790.866 pts</pdfPageSize></qualityIndicators><title>Approach to a Child with Acute Flaccid Paralysis</title><genre><json:string>review-article</json:string></genre><host><title>The Indian Journal of Pediatrics</title><language><json:string>unknown</json:string></language><publicationDate>2012</publicationDate><copyrightDate>2012</copyrightDate><issn><json:string>0019-5456</json:string></issn><eissn><json:string>0973-7693</json:string></eissn><journalId><json:string>12098</json:string></journalId><volume>79</volume><issue>10</issue><pages><first>1351</first><last>1357</last></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>SC11</value></json:item><json:item><value>Pediatrics</value></json:item><json:item><value>Gynecology</value></json:item></subject></host><ark><json:string>ark:/67375/VQC-070SB7BN-6</json:string></ark><publicationDate>2012</publicationDate><copyrightDate>2012</copyrightDate><doi><json:string>10.1007/s12098-012-0831-8</json:string></doi><id>C3A2F03BDAE1BCCBCF6AE7782E13C5B0867AB415</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-070SB7BN-6/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-070SB7BN-6/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/VQC-070SB7BN-6/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Approach to a Child with Acute Flaccid Paralysis</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher scheme="https://scientific-publisher.data.istex.fr">Springer-Verlag</publisher><pubPlace>India</pubPlace><availability><licence><p>Dr. K C Chaudhuri Foundation, 2012</p></licence><p scheme="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</p></availability><date>2012-01-26</date></publicationStmt><notesStmt><note type="review-article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-L5L7X3NF-P">review-article</note><note type="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note><note>Symposium on PGIMER Protocols in Neurological Emergencies</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Approach to a Child with Acute Flaccid Paralysis</title><author xml:id="author-0000" corresp="yes"><persName><forename type="first">Sunit</forename><surname>Singhi</surname></persName><email>sunit.singhi@gmail.com</email><affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Naveen</forename><surname>Sankhyan</surname></persName><affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Ravi</forename><surname>Shah</surname></persName><affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Pratibha</forename><surname>Singhi</surname></persName><affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</affiliation></author><idno type="istex">C3A2F03BDAE1BCCBCF6AE7782E13C5B0867AB415</idno><idno type="ark">ark:/67375/VQC-070SB7BN-6</idno><idno type="DOI">10.1007/s12098-012-0831-8</idno><idno type="article-id">831</idno><idno type="article-id">s12098-012-0831-8</idno></analytic><monogr><title level="j">The Indian Journal of Pediatrics</title><title level="j" type="abbrev">Indian J Pediatr</title><idno type="pISSN">0019-5456</idno><idno type="eISSN">0973-7693</idno><idno type="journal-ID">true</idno><idno type="issue-article-count">27</idno><idno type="volume-issue-count">12</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>India</pubPlace><date type="published" when="2012-10-01"></date><biblScope unit="volume">79</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1351">1351</biblScope><biblScope unit="page" to="1357">1357</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2012-01-26</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Abstract: Acute flaccid paralysis (AFP) is a clinical syndrome characterized by rapid onset weakness, that many times includes respiratory and bulbar weakness. AFP is a broad clinical entity with an array of diagnostic possibilities. An accurate and early diagnosis of the cause has important bearing on the management and prognosis. The immediate priorities in a child who presents with acute progressive weakness are; to detect and manage respiratory muscle weakness, to detect and manage bulbar weakness, evaluate for cardiovascular instability, detect and manage dyselectrolytemia or toxemia, and to detect and manage a spinal compression (traumatic, intraspinal collections). Urgent imaging of the spine is needed in settings where a spinal cord involvement is suspected. Compressive or traumatic spinal lesions may need early neurosurgical intervention. Anterior horn cell injury is usually due to direct viral infection. More distal pathologies are generally immune mediated and respond to immunomodulation. Irrespective of the cause, generalized weakness frequently affects respiratory and bulbar function. Such children need careful monitoring and respiratory support.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Polio</term></item><item><term>Acute weakness</term></item><item><term>Paraparesis</term></item><item><term>Transverse myelitis</term></item><item><term>Guillain Barre syndrome</term></item></list></keywords></textClass><textClass><keywords scheme="Journal-Subject-Collection"><list><label>Medicine</label><item><term>SC11</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Medicine & Public Health</head><item><term>Pediatrics</term></item><item><term>Gynecology</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2012-01-26">Created</change><change when="2012-10-01">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-070SB7BN-6/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus springer-journals not found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//Springer-Verlag//DTD A++ V2.4//EN" URI="http://devel.springer.de/A++/V2.4/DTD/A++V2.4.dtd" name="istex:docType"></istex:docType><istex:document><Publisher><PublisherInfo><PublisherName>Springer-Verlag</PublisherName><PublisherLocation>India</PublisherLocation></PublisherInfo><Journal OutputMedium="All"><JournalInfo JournalProductType="ArchiveJournal" NumberingStyle="Unnumbered"><JournalID>12098</JournalID><JournalPrintISSN>0019-5456</JournalPrintISSN><JournalElectronicISSN>0973-7693</JournalElectronicISSN><JournalTitle>The Indian Journal of Pediatrics</JournalTitle><JournalAbbreviatedTitle>Indian J Pediatr</JournalAbbreviatedTitle><JournalSubjectGroup><JournalSubject Type="Primary">Medicine & Public Health</JournalSubject><JournalSubject Type="Secondary">Pediatrics</JournalSubject><JournalSubject Type="Secondary">Gynecology</JournalSubject><SubjectCollection Code="Medicine">SC11</SubjectCollection></JournalSubjectGroup></JournalInfo><Volume OutputMedium="All"><VolumeInfo TocLevels="0" VolumeType="Regular"><VolumeIDStart>79</VolumeIDStart><VolumeIDEnd>79</VolumeIDEnd><VolumeIssueCount>12</VolumeIssueCount></VolumeInfo><Issue IssueType="Regular" OutputMedium="All"><IssueInfo IssueType="Regular" TocLevels="0"><IssueIDStart>10</IssueIDStart><IssueIDEnd>10</IssueIDEnd><IssueArticleCount>27</IssueArticleCount><IssueHistory><OnlineDate><Year>2012</Year><Month>9</Month><Day>28</Day></OnlineDate><PrintDate><Year>2012</Year><Month>9</Month><Day>27</Day></PrintDate><CoverDate><Year>2012</Year><Month>10</Month></CoverDate><PricelistYear>2012</PricelistYear></IssueHistory><IssueCopyright><CopyrightHolderName>Dr. K C Chaudhuri Foundation</CopyrightHolderName><CopyrightYear>2012</CopyrightYear></IssueCopyright></IssueInfo><Article ID="s12098-012-0831-8" OutputMedium="All"><ArticleInfo ArticleType="ReviewPaper" ContainsESM="No" Language="En" NumberingStyle="Unnumbered" TocLevels="0"><ArticleID>831</ArticleID><ArticleDOI>10.1007/s12098-012-0831-8</ArticleDOI><ArticleSequenceNumber>9</ArticleSequenceNumber><ArticleTitle Language="En">Approach to a Child with Acute Flaccid Paralysis</ArticleTitle><ArticleCategory>Symposium on PGIMER Protocols in Neurological Emergencies</ArticleCategory><ArticleFirstPage>1351</ArticleFirstPage><ArticleLastPage>1357</ArticleLastPage><ArticleHistory><RegistrationDate><Year>2012</Year><Month>6</Month><Day>8</Day></RegistrationDate><Received><Year>2012</Year><Month>1</Month><Day>26</Day></Received><Accepted><Year>2012</Year><Month>6</Month><Day>8</Day></Accepted><OnlineDate><Year>2012</Year><Month>7</Month><Day>12</Day></OnlineDate></ArticleHistory><ArticleCopyright><CopyrightHolderName>Dr. K C Chaudhuri Foundation</CopyrightHolderName><CopyrightYear>2012</CopyrightYear></ArticleCopyright><ArticleGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ArticleGrants></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Sunit</GivenName><GivenName>C.</GivenName><FamilyName>Singhi</FamilyName></AuthorName><Contact><Email>sunit.singhi@gmail.com</Email></Contact></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Naveen</GivenName><FamilyName>Sankhyan</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Ravi</GivenName><FamilyName>Shah</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Pratibha</GivenName><FamilyName>Singhi</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgDivision>Department of Pediatrics</OrgDivision><OrgName>Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER)</OrgName><OrgAddress><City>Chandigarh</City><Postcode>160012</Postcode><Country Code="IN">India</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En" OutputMedium="All"><Heading>Abstract</Heading><Para>Acute flaccid paralysis (AFP) is a clinical syndrome characterized by rapid onset weakness, that many times includes respiratory and bulbar weakness. AFP is a broad clinical entity with an array of diagnostic possibilities. An accurate and early diagnosis of the cause has important bearing on the management and prognosis. The immediate priorities in a child who presents with acute progressive weakness are; <Emphasis Type="Italic">to detect and manage respiratory muscle weakness</Emphasis>, <Emphasis Type="Italic">to detect and manage bulbar weakness</Emphasis>, <Emphasis Type="Italic">evaluate for cardiovascular instability</Emphasis>, <Emphasis Type="Italic">detect and manage dyselectrolytemia or toxemia, and to detect and manage a spinal compression (traumatic, intraspinal collections).</Emphasis> Urgent imaging of the spine is needed in settings where a spinal cord involvement is suspected. Compressive or traumatic spinal lesions may need early neurosurgical intervention. Anterior horn cell injury is usually due to direct viral infection. More distal pathologies are generally immune mediated and respond to immunomodulation. Irrespective of the cause, generalized weakness frequently affects respiratory and bulbar function. Such children need careful monitoring and respiratory support.</Para></Abstract><KeywordGroup Language="En" OutputMedium="All"><Heading>Keywords</Heading><Keyword>Polio</Keyword><Keyword>Acute weakness</Keyword><Keyword>Paraparesis</Keyword><Keyword>Transverse myelitis</Keyword><Keyword>Guillain Barre syndrome</Keyword></KeywordGroup></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Approach to a Child with Acute Flaccid Paralysis</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Approach to a Child with Acute Flaccid Paralysis</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Sunit</namePart><namePart type="given">C.</namePart><namePart type="family">Singhi</namePart><affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</affiliation><affiliation>E-mail: sunit.singhi@gmail.com</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Naveen</namePart><namePart type="family">Sankhyan</namePart><affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ravi</namePart><namePart type="family">Shah</namePart><affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Pratibha</namePart><namePart type="family">Singhi</namePart><affiliation>Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), 160012, Chandigarh, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="ReviewPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-L5L7X3NF-P">review-article</genre><originInfo><publisher>Springer-Verlag</publisher><place><placeTerm type="text">India</placeTerm></place><dateCreated encoding="w3cdtf">2012-01-26</dateCreated><dateIssued encoding="w3cdtf">2012-10-01</dateIssued><copyrightDate encoding="w3cdtf">2012</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Acute flaccid paralysis (AFP) is a clinical syndrome characterized by rapid onset weakness, that many times includes respiratory and bulbar weakness. AFP is a broad clinical entity with an array of diagnostic possibilities. An accurate and early diagnosis of the cause has important bearing on the management and prognosis. The immediate priorities in a child who presents with acute progressive weakness are; to detect and manage respiratory muscle weakness, to detect and manage bulbar weakness, evaluate for cardiovascular instability, detect and manage dyselectrolytemia or toxemia, and to detect and manage a spinal compression (traumatic, intraspinal collections). Urgent imaging of the spine is needed in settings where a spinal cord involvement is suspected. Compressive or traumatic spinal lesions may need early neurosurgical intervention. Anterior horn cell injury is usually due to direct viral infection. More distal pathologies are generally immune mediated and respond to immunomodulation. Irrespective of the cause, generalized weakness frequently affects respiratory and bulbar function. Such children need careful monitoring and respiratory support.</abstract><note>Symposium on PGIMER Protocols in Neurological Emergencies</note><subject lang="en"><genre>Keywords</genre><topic>Polio</topic><topic>Acute weakness</topic><topic>Paraparesis</topic><topic>Transverse myelitis</topic><topic>Guillain Barre syndrome</topic></subject><relatedItem type="host"><titleInfo><title>The Indian Journal of Pediatrics</title></titleInfo><titleInfo type="abbreviated"><title>Indian J Pediatr</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>Springer</publisher><dateIssued encoding="w3cdtf">2012-09-28</dateIssued><copyrightDate encoding="w3cdtf">2012</copyrightDate></originInfo><subject><genre>Journal-Subject-Collection</genre><topic authority="SpringerSubjectCodes" authorityURI="Medicine">SC11</topic></subject><subject><genre>Medicine & Public Health</genre><topic>Pediatrics</topic><topic>Gynecology</topic></subject><identifier type="ISSN">0019-5456</identifier><identifier type="eISSN">0973-7693</identifier><identifier type="JournalID">12098</identifier><identifier type="IssueArticleCount">27</identifier><identifier type="VolumeIssueCount">12</identifier><part><date>2012</date><detail type="volume"><number>79</number><caption>vol.</caption></detail><detail type="issue"><number>10</number><caption>no.</caption></detail><extent unit="pages"><start>1351</start><end>1357</end></extent></part><recordInfo><recordOrigin>Dr. K C Chaudhuri Foundation, 2012</recordOrigin></recordInfo></relatedItem><identifier type="istex">C3A2F03BDAE1BCCBCF6AE7782E13C5B0867AB415</identifier><identifier type="ark">ark:/67375/VQC-070SB7BN-6</identifier><identifier type="DOI">10.1007/s12098-012-0831-8</identifier><identifier type="ArticleID">831</identifier><identifier type="ArticleID">s12098-012-0831-8</identifier><accessCondition type="use and reproduction" contentType="copyright">Dr. K C Chaudhuri Foundation, 2012</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</recordContentSource><recordOrigin>Dr. K C Chaudhuri Foundation, 2012</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-070SB7BN-6/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/StressCovidV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C23 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000C23 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= StressCovidV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:C3A2F03BDAE1BCCBCF6AE7782E13C5B0867AB415
|texte= Approach to a Child with Acute Flaccid Paralysis
}}
| This area was generated with Dilib version V0.6.33. |  |