Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis
Identifieur interne : 000963 ( Istex/Corpus ); précédent : 000962; suivant : 000964Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis
Auteurs : Guizhao Liang ; Zecong Chen ; Shanbin Yang ; Hu Mei ; Yuan Zhou ; Li Yang ; Peng Zhou ; Shengxi Yang ; Mao Shu ; Chunyang Liao ; Shirong Wu ; Genrong Li ; Liu He ; Jiankun Gao ; Mengyu Gan ; Dejing Li ; Guoping Chen ; Guixue Wang ; Sha Long ; Juhua Jing ; Xiaolin Zheng ; Hui Zeng ; Qiaoxia Zhang ; Mengjun Zhang ; Qi Yang ; Feifei Tian ; Jianbo Tong ; Jiaona Wang ; Yonghong Liu ; Bo Li ; Liangjia Qiu ; Shaoxi Cai ; Na Zhao ; Yan Yang ; Xiali Su ; Jian Song ; Meixia Chen ; Xuejiao Zhang ; Jiaying Sun ; Jingwei Li ; Guohua Chen ; Gang Chen ; Jie Deng ; Chuanyou Peng ; Wanping Zhu ; Luonan Xu ; Yuquan Wu ; Limin Liao ; Zhi Li ; Jun Li ; Dajun Lu ; Qinliang Su ; Zhenghu Huang ; Ping Zhou ; Zhiliang LiSource :
- Science in China Series B: Chemistry [ 1006-9291 ] ; 2008-02-01.
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Abstract
Abstract: Total 200 properties related to structural characteristics were employed to represent structures of 400 HA coded proteins of influenza virus as training samples. Some recognition models for HA proteins of avian influenza virus (AIV) were developed using support vector machine (SVM) and linear discriminant analysis (LDA). The results obtained from LDA are as follows: the identification accuracy (R ia ) for training samples is 99.8% and R ia by leave one out cross validation is 99.5%. Both R ia of 99.8% for training samples and R ia of 99.3% by leave one out cross validation are obtained using SVM model, respectively. External 200 HA proteins of influenza virus were used to validate the external predictive power of the resulting model. The external R ia for them is 95.5% by LDA and 96.5% by SVM, respectively, which shows that HA proteins of AIVs are preferably recognized by SVM and LDA, and the performances by SVM are superior to those by LDA.
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DOI: 10.1007/s11426-008-0006-7
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Chen</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Shanbin" sort="Yang, Shanbin" uniqKey="Yang S" first="Shanbin" last="Yang">Shanbin Yang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Mei, Hu" sort="Mei, Hu" uniqKey="Mei H" first="Hu" last="Mei">Hu Mei</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhou, Yuan" sort="Zhou, Yuan" uniqKey="Zhou Y" first="Yuan" last="Zhou">Yuan Zhou</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Li" sort="Yang, Li" uniqKey="Yang L" first="Li" last="Yang">Li Yang</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhou, Peng" sort="Zhou, Peng" uniqKey="Zhou P" first="Peng" last="Zhou">Peng Zhou</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Shengxi" sort="Yang, Shengxi" uniqKey="Yang S" first="Shengxi" last="Yang">Shengxi Yang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Shu, Mao" sort="Shu, Mao" uniqKey="Shu M" first="Mao" last="Shu">Mao Shu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Liao, Chunyang" sort="Liao, Chunyang" uniqKey="Liao C" first="Chunyang" last="Liao">Chunyang Liao</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Wu, Shirong" sort="Wu, Shirong" uniqKey="Wu S" first="Shirong" last="Wu">Shirong Wu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Genrong" sort="Li, Genrong" uniqKey="Li G" first="Genrong" last="Li">Genrong Li</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="He, Liu" sort="He, Liu" uniqKey="He L" first="Liu" last="He">Liu He</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Gao, Jiankun" sort="Gao, Jiankun" uniqKey="Gao J" first="Jiankun" last="Gao">Jiankun Gao</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Gan, Mengyu" sort="Gan, Mengyu" uniqKey="Gan M" first="Mengyu" last="Gan">Mengyu Gan</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Dejing" sort="Li, Dejing" uniqKey="Li D" first="Dejing" last="Li">Dejing Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Guoping" sort="Chen, Guoping" uniqKey="Chen G" first="Guoping" last="Chen">Guoping Chen</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Wang, Guixue" sort="Wang, Guixue" uniqKey="Wang G" first="Guixue" last="Wang">Guixue Wang</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Long, Sha" sort="Long, Sha" uniqKey="Long S" first="Sha" last="Long">Sha Long</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Jing, Juhua" sort="Jing, Juhua" uniqKey="Jing J" first="Juhua" last="Jing">Juhua Jing</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zheng, Xiaolin" sort="Zheng, Xiaolin" uniqKey="Zheng X" first="Xiaolin" last="Zheng">Xiaolin Zheng</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zeng, Hui" sort="Zeng, Hui" uniqKey="Zeng H" first="Hui" last="Zeng">Hui Zeng</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhang, Qiaoxia" sort="Zhang, Qiaoxia" uniqKey="Zhang Q" first="Qiaoxia" last="Zhang">Qiaoxia Zhang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhang, Mengjun" sort="Zhang, Mengjun" uniqKey="Zhang M" first="Mengjun" last="Zhang">Mengjun Zhang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Qi" sort="Yang, Qi" uniqKey="Yang Q" first="Qi" last="Yang">Qi Yang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Tian, Feifei" sort="Tian, Feifei" uniqKey="Tian F" first="Feifei" last="Tian">Feifei Tian</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Tong, Jianbo" sort="Tong, Jianbo" uniqKey="Tong J" first="Jianbo" last="Tong">Jianbo Tong</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Wang, Jiaona" sort="Wang, Jiaona" uniqKey="Wang J" first="Jiaona" last="Wang">Jiaona Wang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Liu, Yonghong" sort="Liu, Yonghong" uniqKey="Liu Y" first="Yonghong" last="Liu">Yonghong Liu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Bo" sort="Li, Bo" uniqKey="Li B" first="Bo" last="Li">Bo Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Qiu, Liangjia" sort="Qiu, Liangjia" uniqKey="Qiu L" first="Liangjia" last="Qiu">Liangjia Qiu</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Cai, Shaoxi" sort="Cai, Shaoxi" uniqKey="Cai S" first="Shaoxi" last="Cai">Shaoxi Cai</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhao, Na" sort="Zhao, Na" uniqKey="Zhao N" first="Na" last="Zhao">Na Zhao</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Yan" sort="Yang, Yan" uniqKey="Yang Y" first="Yan" last="Yang">Yan Yang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Su, Xiali" sort="Su, Xiali" uniqKey="Su X" first="Xiali" last="Su">Xiali Su</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Song, Jian" sort="Song, Jian" uniqKey="Song J" first="Jian" last="Song">Jian Song</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Meixia" sort="Chen, Meixia" uniqKey="Chen M" first="Meixia" last="Chen">Meixia Chen</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhang, Xuejiao" sort="Zhang, Xuejiao" uniqKey="Zhang X" first="Xuejiao" last="Zhang">Xuejiao Zhang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Sun, Jiaying" sort="Sun, Jiaying" uniqKey="Sun J" first="Jiaying" last="Sun">Jiaying Sun</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Jingwei" sort="Li, Jingwei" uniqKey="Li J" first="Jingwei" last="Li">Jingwei Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Guohua" sort="Chen, Guohua" uniqKey="Chen G" first="Guohua" last="Chen">Guohua Chen</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Gang" sort="Chen, Gang" uniqKey="Chen G" first="Gang" last="Chen">Gang Chen</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Technology Centre for Life Sciences and Biotechnology, Singapore Polytechnic, 139651, Singapore, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Deng, Jie" sort="Deng, Jie" uniqKey="Deng J" first="Jie" last="Deng">Jie Deng</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Peng, Chuanyou" sort="Peng, Chuanyou" uniqKey="Peng C" first="Chuanyou" last="Peng">Chuanyou Peng</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhu, Wanping" sort="Zhu, Wanping" uniqKey="Zhu W" first="Wanping" last="Zhu">Wanping Zhu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Xu, Luonan" sort="Xu, Luonan" uniqKey="Xu L" first="Luonan" last="Xu">Luonan Xu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Wu, Yuquan" sort="Wu, Yuquan" uniqKey="Wu Y" first="Yuquan" last="Wu">Yuquan Wu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Liao, Limin" sort="Liao, Limin" uniqKey="Liao L" first="Limin" last="Liao">Limin Liao</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Zhi" sort="Li, Zhi" uniqKey="Li Z" first="Zhi" last="Li">Zhi Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Jun" sort="Li, Jun" uniqKey="Li J" first="Jun" last="Li">Jun Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Lu, Dajun" sort="Lu, Dajun" uniqKey="Lu D" first="Dajun" last="Lu">Dajun Lu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Su, Qinliang" sort="Su, Qinliang" uniqKey="Su Q" first="Qinliang" last="Su">Qinliang Su</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Huang, Zhenghu" sort="Huang, Zhenghu" uniqKey="Huang Z" first="Zhenghu" last="Huang">Zhenghu Huang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhou, Ping" sort="Zhou, Ping" uniqKey="Zhou P" first="Ping" last="Zhou">Ping Zhou</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Zhiliang" sort="Li, Zhiliang" uniqKey="Li Z" first="Zhiliang" last="Li">Zhiliang Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: zlli-cqu@163.com</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: zlli2662@163.com</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: sdqdlgz@163.com</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6DA673A68B4BADCE4DCEAA9F13A3D9883CD3C48D</idno><date when="2008" year="2008">2008</date><idno type="doi">10.1007/s11426-008-0006-7</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-9KHLS7DM-V/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000963</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000963</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis</title><author><name sortKey="Liang, Guizhao" sort="Liang, Guizhao" uniqKey="Liang G" first="Guizhao" last="Liang">Guizhao Liang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Zecong" sort="Chen, Zecong" uniqKey="Chen Z" first="Zecong" last="Chen">Zecong Chen</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Shanbin" sort="Yang, Shanbin" uniqKey="Yang S" first="Shanbin" last="Yang">Shanbin Yang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Mei, Hu" sort="Mei, Hu" uniqKey="Mei H" first="Hu" last="Mei">Hu Mei</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhou, Yuan" sort="Zhou, Yuan" uniqKey="Zhou Y" first="Yuan" last="Zhou">Yuan Zhou</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Li" sort="Yang, Li" uniqKey="Yang L" first="Li" last="Yang">Li Yang</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhou, Peng" sort="Zhou, Peng" uniqKey="Zhou P" first="Peng" last="Zhou">Peng Zhou</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Shengxi" sort="Yang, Shengxi" uniqKey="Yang S" first="Shengxi" last="Yang">Shengxi Yang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Shu, Mao" sort="Shu, Mao" uniqKey="Shu M" first="Mao" last="Shu">Mao Shu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Liao, Chunyang" sort="Liao, Chunyang" uniqKey="Liao C" first="Chunyang" last="Liao">Chunyang Liao</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Wu, Shirong" sort="Wu, Shirong" uniqKey="Wu S" first="Shirong" last="Wu">Shirong Wu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Genrong" sort="Li, Genrong" uniqKey="Li G" first="Genrong" last="Li">Genrong Li</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="He, Liu" sort="He, Liu" uniqKey="He L" first="Liu" last="He">Liu He</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Gao, Jiankun" sort="Gao, Jiankun" uniqKey="Gao J" first="Jiankun" last="Gao">Jiankun Gao</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Gan, Mengyu" sort="Gan, Mengyu" uniqKey="Gan M" first="Mengyu" last="Gan">Mengyu Gan</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Dejing" sort="Li, Dejing" uniqKey="Li D" first="Dejing" last="Li">Dejing Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Guoping" sort="Chen, Guoping" uniqKey="Chen G" first="Guoping" last="Chen">Guoping Chen</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Wang, Guixue" sort="Wang, Guixue" uniqKey="Wang G" first="Guixue" last="Wang">Guixue Wang</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Long, Sha" sort="Long, Sha" uniqKey="Long S" first="Sha" last="Long">Sha Long</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Jing, Juhua" sort="Jing, Juhua" uniqKey="Jing J" first="Juhua" last="Jing">Juhua Jing</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zheng, Xiaolin" sort="Zheng, Xiaolin" uniqKey="Zheng X" first="Xiaolin" last="Zheng">Xiaolin Zheng</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zeng, Hui" sort="Zeng, Hui" uniqKey="Zeng H" first="Hui" last="Zeng">Hui Zeng</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhang, Qiaoxia" sort="Zhang, Qiaoxia" uniqKey="Zhang Q" first="Qiaoxia" last="Zhang">Qiaoxia Zhang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhang, Mengjun" sort="Zhang, Mengjun" uniqKey="Zhang M" first="Mengjun" last="Zhang">Mengjun Zhang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Qi" sort="Yang, Qi" uniqKey="Yang Q" first="Qi" last="Yang">Qi Yang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Tian, Feifei" sort="Tian, Feifei" uniqKey="Tian F" first="Feifei" last="Tian">Feifei Tian</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Tong, Jianbo" sort="Tong, Jianbo" uniqKey="Tong J" first="Jianbo" last="Tong">Jianbo Tong</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Wang, Jiaona" sort="Wang, Jiaona" uniqKey="Wang J" first="Jiaona" last="Wang">Jiaona Wang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Liu, Yonghong" sort="Liu, Yonghong" uniqKey="Liu Y" first="Yonghong" last="Liu">Yonghong Liu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Bo" sort="Li, Bo" uniqKey="Li B" first="Bo" last="Li">Bo Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Qiu, Liangjia" sort="Qiu, Liangjia" uniqKey="Qiu L" first="Liangjia" last="Qiu">Liangjia Qiu</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Cai, Shaoxi" sort="Cai, Shaoxi" uniqKey="Cai S" first="Shaoxi" last="Cai">Shaoxi Cai</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhao, Na" sort="Zhao, Na" uniqKey="Zhao N" first="Na" last="Zhao">Na Zhao</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Yang, Yan" sort="Yang, Yan" uniqKey="Yang Y" first="Yan" last="Yang">Yan Yang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Su, Xiali" sort="Su, Xiali" uniqKey="Su X" first="Xiali" last="Su">Xiali Su</name><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Song, Jian" sort="Song, Jian" uniqKey="Song J" first="Jian" last="Song">Jian Song</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Meixia" sort="Chen, Meixia" uniqKey="Chen M" first="Meixia" last="Chen">Meixia Chen</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhang, Xuejiao" sort="Zhang, Xuejiao" uniqKey="Zhang X" first="Xuejiao" last="Zhang">Xuejiao Zhang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Sun, Jiaying" sort="Sun, Jiaying" uniqKey="Sun J" first="Jiaying" last="Sun">Jiaying Sun</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Jingwei" sort="Li, Jingwei" uniqKey="Li J" first="Jingwei" last="Li">Jingwei Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Guohua" sort="Chen, Guohua" uniqKey="Chen G" first="Guohua" last="Chen">Guohua Chen</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Chen, Gang" sort="Chen, Gang" uniqKey="Chen G" first="Gang" last="Chen">Gang Chen</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Technology Centre for Life Sciences and Biotechnology, Singapore Polytechnic, 139651, Singapore, Singapore</mods:affiliation></affiliation></author><author><name sortKey="Deng, Jie" sort="Deng, Jie" uniqKey="Deng J" first="Jie" last="Deng">Jie Deng</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Peng, Chuanyou" sort="Peng, Chuanyou" uniqKey="Peng C" first="Chuanyou" last="Peng">Chuanyou Peng</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhu, Wanping" sort="Zhu, Wanping" uniqKey="Zhu W" first="Wanping" last="Zhu">Wanping Zhu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Xu, Luonan" sort="Xu, Luonan" uniqKey="Xu L" first="Luonan" last="Xu">Luonan Xu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Wu, Yuquan" sort="Wu, Yuquan" uniqKey="Wu Y" first="Yuquan" last="Wu">Yuquan Wu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Liao, Limin" sort="Liao, Limin" uniqKey="Liao L" first="Limin" last="Liao">Limin Liao</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Zhi" sort="Li, Zhi" uniqKey="Li Z" first="Zhi" last="Li">Zhi Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Jun" sort="Li, Jun" uniqKey="Li J" first="Jun" last="Li">Jun Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Lu, Dajun" sort="Lu, Dajun" uniqKey="Lu D" first="Dajun" last="Lu">Dajun Lu</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Su, Qinliang" sort="Su, Qinliang" uniqKey="Su Q" first="Qinliang" last="Su">Qinliang Su</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Huang, Zhenghu" sort="Huang, Zhenghu" uniqKey="Huang Z" first="Zhenghu" last="Huang">Zhenghu Huang</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Zhou, Ping" sort="Zhou, Ping" uniqKey="Zhou P" first="Ping" last="Zhou">Ping Zhou</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation></author><author><name sortKey="Li, Zhiliang" sort="Li, Zhiliang" uniqKey="Li Z" first="Zhiliang" last="Li">Zhiliang Li</name><affiliation><mods:affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: zlli-cqu@163.com</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: zlli2662@163.com</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: sdqdlgz@163.com</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Science in China Series B: Chemistry</title><title level="j" type="abbrev">Sci. China Ser. B-Chem.</title><idno type="ISSN">1006-9291</idno><idno type="eISSN">1862-2771</idno><imprint><publisher>Science in China Press; www.scichina.com</publisher><pubPlace>Beijing</pubPlace><date type="published" when="2008-02-01">2008-02-01</date><biblScope unit="volume">51</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="166">166</biblScope><biblScope unit="page" to="170">170</biblScope></imprint><idno type="ISSN">1006-9291</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1006-9291</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>HA protein</term><term>avian influenza virus (AIV)</term><term>linear discriminant analysis (LDA)</term><term>support vector machine (SVM)</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Total 200 properties related to structural characteristics were employed to represent structures of 400 HA coded proteins of influenza virus as training samples. Some recognition models for HA proteins of avian influenza virus (AIV) were developed using support vector machine (SVM) and linear discriminant analysis (LDA). The results obtained from LDA are as follows: the identification accuracy (R ia ) for training samples is 99.8% and R ia by leave one out cross validation is 99.5%. Both R ia of 99.8% for training samples and R ia of 99.3% by leave one out cross validation are obtained using SVM model, respectively. External 200 HA proteins of influenza virus were used to validate the external predictive power of the resulting model. The external R ia for them is 95.5% by LDA and 96.5% by SVM, respectively, which shows that HA proteins of AIVs are preferably recognized by SVM and LDA, and the performances by SVM are superior to those by LDA.</div></front></TEI><istex><corpusName>springer-journals</corpusName><author><json:item><name>GuiZhao Liang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ZeCong Chen</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ShanBin Yang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Hu Mei</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Yuan Zhou</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Li Yang</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Peng Zhou</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ShengXi Yang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Mao Shu</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ChunYang Liao</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ShiRong Wu</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>GenRong Li</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Liu He</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>JianKun Gao</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>MengYu Gan</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>DeJing Li</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>GuoPing Chen</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>GuiXue Wang</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Sha Long</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>JuHua Jing</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>XiaoLin Zheng</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Hui Zeng</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>QiaoXia Zhang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>MengJun Zhang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Qi Yang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>FeiFei Tian</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>JianBo Tong</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>JiaoNa Wang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>YongHong Liu</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Bo Li</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>LiangJia Qiu</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ShaoXi Cai</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Na Zhao</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Yan Yang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>XiaLi Su</name><affiliations><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Jian Song</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>MeiXia Chen</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>XueJiao Zhang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>JiaYing Sun</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>JingWei Li</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>GuoHua Chen</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Gang Chen</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Technology Centre for Life Sciences and Biotechnology, Singapore Polytechnic, 139651, Singapore, Singapore</json:string></affiliations></json:item><json:item><name>Jie Deng</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ChuanYou Peng</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>WanPing Zhu</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>LuoNan Xu</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>College of Bioengineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>YuQuan Wu</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>LiMin Liao</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Zhi Li</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Jun Li</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>DaJun Lu</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>QinLiang Su</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ZhengHu Huang</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>Ping Zhou</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string></affiliations></json:item><json:item><name>ZhiLiang Li</name><affiliations><json:string>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</json:string><json:string>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</json:string><json:string>E-mail: zlli-cqu@163.com</json:string><json:string>E-mail: zlli2662@163.com</json:string><json:string>E-mail: sdqdlgz@163.com</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>avian influenza virus (AIV)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>HA protein</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>support vector machine (SVM)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>linear discriminant analysis (LDA)</value></json:item></subject><articleId><json:string>6</json:string><json:string>s11426-008-0006-7</json:string></articleId><arkIstex>ark:/67375/VQC-9KHLS7DM-V</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>OriginalPaper</json:string></originalGenre><abstract>Abstract: Total 200 properties related to structural characteristics were employed to represent structures of 400 HA coded proteins of influenza virus as training samples. Some recognition models for HA proteins of avian influenza virus (AIV) were developed using support vector machine (SVM) and linear discriminant analysis (LDA). The results obtained from LDA are as follows: the identification accuracy (R ia ) for training samples is 99.8% and R ia by leave one out cross validation is 99.5%. Both R ia of 99.8% for training samples and R ia of 99.3% by leave one out cross validation are obtained using SVM model, respectively. External 200 HA proteins of influenza virus were used to validate the external predictive power of the resulting model. The external R ia for them is 95.5% by LDA and 96.5% by SVM, respectively, which shows that HA proteins of AIVs are preferably recognized by SVM and LDA, and the performances by SVM are superior to those by LDA.</abstract><qualityIndicators><score>8.383</score><pdfWordCount>4451</pdfWordCount><pdfCharCount>50977</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>21</pdfPageCount><pdfPageSize>595.22 x 842 pts (A4)</pdfPageSize><refBibsNative>false</refBibsNative><abstractWordCount>161</abstractWordCount><abstractCharCount>965</abstractCharCount><keywordCount>4</keywordCount></qualityIndicators><title>Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis</title><genre><json:string>research-article</json:string></genre><host><title>Science in China Series B: Chemistry</title><language><json:string>unknown</json:string></language><publicationDate>2008</publicationDate><copyrightDate>2008</copyrightDate><issn><json:string>1006-9291</json:string></issn><eissn><json:string>1862-2771</json:string></eissn><journalId><json:string>11426</json:string></journalId><volume>51</volume><issue>2</issue><pages><first>166</first><last>170</last></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Chemistry</value></json:item><json:item><value>Chemistry/Food Science, general</value></json:item></subject></host><ark><json:string>ark:/67375/VQC-9KHLS7DM-V</json:string></ark><publicationDate>2008</publicationDate><copyrightDate>2008</copyrightDate><doi><json:string>10.1007/s11426-008-0006-7</json:string></doi><id>6DA673A68B4BADCE4DCEAA9F13A3D9883CD3C48D</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-9KHLS7DM-V/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-9KHLS7DM-V/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/VQC-9KHLS7DM-V/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher scheme="https://scientific-publisher.data.istex.fr">Science in China Press; www.scichina.com</publisher><pubPlace>Beijing</pubPlace><availability><licence><p>Science in China Press, 2008</p></licence><p scheme="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</p></availability><date>2005-11-27</date></publicationStmt><notesStmt><note type="research-article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</note><note type="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis</title><author xml:id="author-0000"><persName><forename type="first">GuiZhao</forename><surname>Liang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0001"><persName><forename type="first">ZeCong</forename><surname>Chen</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0002"><persName><forename type="first">ShanBin</forename><surname>Yang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Hu</forename><surname>Mei</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Yuan</forename><surname>Zhou</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0005"><persName><forename type="first">Li</forename><surname>Yang</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0006"><persName><forename type="first">Peng</forename><surname>Zhou</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0007"><persName><forename type="first">ShengXi</forename><surname>Yang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0008"><persName><forename type="first">Mao</forename><surname>Shu</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0009"><persName><forename type="first">ChunYang</forename><surname>Liao</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0010"><persName><forename type="first">ShiRong</forename><surname>Wu</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0011"><persName><forename type="first">GenRong</forename><surname>Li</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0012"><persName><forename type="first">Liu</forename><surname>He</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0013"><persName><forename type="first">JianKun</forename><surname>Gao</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0014"><persName><forename type="first">MengYu</forename><surname>Gan</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0015"><persName><forename type="first">DeJing</forename><surname>Li</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0016"><persName><forename type="first">GuoPing</forename><surname>Chen</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0017"><persName><forename type="first">GuiXue</forename><surname>Wang</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0018"><persName><forename type="first">Sha</forename><surname>Long</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0019"><persName><forename type="first">JuHua</forename><surname>Jing</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0020"><persName><forename type="first">XiaoLin</forename><surname>Zheng</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0021"><persName><forename type="first">Hui</forename><surname>Zeng</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0022"><persName><forename type="first">QiaoXia</forename><surname>Zhang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0023"><persName><forename type="first">MengJun</forename><surname>Zhang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0024"><persName><forename type="first">Qi</forename><surname>Yang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0025"><persName><forename type="first">FeiFei</forename><surname>Tian</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0026"><persName><forename type="first">JianBo</forename><surname>Tong</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0027"><persName><forename type="first">JiaoNa</forename><surname>Wang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0028"><persName><forename type="first">YongHong</forename><surname>Liu</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0029"><persName><forename type="first">Bo</forename><surname>Li</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0030"><persName><forename type="first">LiangJia</forename><surname>Qiu</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0031"><persName><forename type="first">ShaoXi</forename><surname>Cai</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0032"><persName><forename type="first">Na</forename><surname>Zhao</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0033"><persName><forename type="first">Yan</forename><surname>Yang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0034"><persName><forename type="first">XiaLi</forename><surname>Su</surname></persName><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0035"><persName><forename type="first">Jian</forename><surname>Song</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0036"><persName><forename type="first">MeiXia</forename><surname>Chen</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0037"><persName><forename type="first">XueJiao</forename><surname>Zhang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0038"><persName><forename type="first">JiaYing</forename><surname>Sun</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0039"><persName><forename type="first">JingWei</forename><surname>Li</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0040"><persName><forename type="first">GuoHua</forename><surname>Chen</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0041"><persName><forename type="first">Gang</forename><surname>Chen</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Technology Centre for Life Sciences and Biotechnology, Singapore Polytechnic, 139651, Singapore, Singapore</affiliation></author><author xml:id="author-0042"><persName><forename type="first">Jie</forename><surname>Deng</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0043"><persName><forename type="first">ChuanYou</forename><surname>Peng</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0044"><persName><forename type="first">WanPing</forename><surname>Zhu</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0045"><persName><forename type="first">LuoNan</forename><surname>Xu</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0046"><persName><forename type="first">YuQuan</forename><surname>Wu</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0047"><persName><forename type="first">LiMin</forename><surname>Liao</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0048"><persName><forename type="first">Zhi</forename><surname>Li</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0049"><persName><forename type="first">Jun</forename><surname>Li</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0050"><persName><forename type="first">DaJun</forename><surname>Lu</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0051"><persName><forename type="first">QinLiang</forename><surname>Su</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0052"><persName><forename type="first">ZhengHu</forename><surname>Huang</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0053"><persName><forename type="first">Ping</forename><surname>Zhou</surname></persName><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><author xml:id="author-0054" corresp="yes"><persName><forename type="first">ZhiLiang</forename><surname>Li</surname></persName><email>zlli-cqu@163.com</email><email>zlli2662@163.com</email><email>sdqdlgz@163.com</email><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation></author><idno type="istex">6DA673A68B4BADCE4DCEAA9F13A3D9883CD3C48D</idno><idno type="ark">ark:/67375/VQC-9KHLS7DM-V</idno><idno type="DOI">10.1007/s11426-008-0006-7</idno><idno type="article-id">6</idno><idno type="article-id">s11426-008-0006-7</idno></analytic><monogr><title level="j">Science in China Series B: Chemistry</title><title level="j" type="abbrev">Sci. China Ser. B-Chem.</title><idno type="pISSN">1006-9291</idno><idno type="eISSN">1862-2771</idno><idno type="journal-ID">true</idno><idno type="journal-SPIN">31919487</idno><idno type="issue-article-count">13</idno><idno type="volume-issue-count">6</idno><imprint><publisher>Science in China Press; www.scichina.com</publisher><pubPlace>Beijing</pubPlace><date type="published" when="2008-02-01"></date><biblScope unit="volume">51</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="166">166</biblScope><biblScope unit="page" to="170">170</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2005-11-27</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Abstract: Total 200 properties related to structural characteristics were employed to represent structures of 400 HA coded proteins of influenza virus as training samples. Some recognition models for HA proteins of avian influenza virus (AIV) were developed using support vector machine (SVM) and linear discriminant analysis (LDA). The results obtained from LDA are as follows: the identification accuracy (R ia ) for training samples is 99.8% and R ia by leave one out cross validation is 99.5%. Both R ia of 99.8% for training samples and R ia of 99.3% by leave one out cross validation are obtained using SVM model, respectively. External 200 HA proteins of influenza virus were used to validate the external predictive power of the resulting model. The external R ia for them is 95.5% by LDA and 96.5% by SVM, respectively, which shows that HA proteins of AIVs are preferably recognized by SVM and LDA, and the performances by SVM are superior to those by LDA.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>avian influenza virus (AIV)</term></item><item><term>HA protein</term></item><item><term>support vector machine (SVM)</term></item><item><term>linear discriminant analysis (LDA)</term></item></list></keywords></textClass><textClass><keywords scheme="Journal-Subject-Group"><list><label>C</label><item><term>Chemistry</term></item><label>C00004</label><item><term>Chemistry/Food Science, general</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2005-11-27">Created</change><change when="2008-02-01">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-9KHLS7DM-V/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus springer-journals not found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//Springer-Verlag//DTD A++ V2.4//EN" URI="http://devel.springer.de/A++/V2.4/DTD/A++V2.4.dtd" name="istex:docType"></istex:docType><istex:document><Publisher><PublisherInfo><PublisherName>Science in China Press</PublisherName><PublisherLocation>Beijing</PublisherLocation><PublisherURL>www.scichina.com</PublisherURL></PublisherInfo><Journal><JournalInfo JournalProductType="ArchiveJournal" NumberingStyle="Unnumbered"><JournalID>11426</JournalID><JournalPrintISSN>1006-9291</JournalPrintISSN><JournalElectronicISSN>1862-2771</JournalElectronicISSN><JournalSPIN>31919487</JournalSPIN><JournalTitle>Science in China Series B: Chemistry</JournalTitle><JournalAbbreviatedTitle>Sci. China Ser. B-Chem.</JournalAbbreviatedTitle><JournalSubjectGroup><JournalSubject Code="C" Type="Primary">Chemistry</JournalSubject><JournalSubject Code="C00004" Priority="1" Type="Secondary">Chemistry/Food Science, general</JournalSubject></JournalSubjectGroup></JournalInfo><Volume><VolumeInfo TocLevels="0" VolumeType="Regular"><VolumeIDStart>51</VolumeIDStart><VolumeIDEnd>51</VolumeIDEnd><VolumeIssueCount>6</VolumeIssueCount></VolumeInfo><Issue IssueType="Regular"><IssueInfo TocLevels="0"><IssueIDStart>2</IssueIDStart><IssueIDEnd>2</IssueIDEnd><IssueArticleCount>13</IssueArticleCount><IssueHistory><CoverDate><Year>2008</Year><Month>2</Month></CoverDate></IssueHistory><IssueCopyright><CopyrightHolderName>Science in China Press</CopyrightHolderName><CopyrightYear>2008</CopyrightYear></IssueCopyright></IssueInfo><Article ID="s11426-008-0006-7"><ArticleInfo ArticleType="OriginalPaper" ContainsESM="No" Language="En" NumberingStyle="Unnumbered" TocLevels="0"><ArticleID>6</ArticleID><ArticleDOI>10.1007/s11426-008-0006-7</ArticleDOI><ArticleSequenceNumber>10</ArticleSequenceNumber><ArticleTitle Language="En">Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis</ArticleTitle><ArticleFirstPage>166</ArticleFirstPage><ArticleLastPage>170</ArticleLastPage><ArticleHistory><RegistrationDate><Year>2008</Year><Month>1</Month><Day>15</Day></RegistrationDate><Received><Year>2005</Year><Month>11</Month><Day>27</Day></Received><Accepted><Year>2006</Year><Month>3</Month><Day>13</Day></Accepted></ArticleHistory><ArticleCopyright><CopyrightHolderName>Science in China Press</CopyrightHolderName><CopyrightYear>2008</CopyrightYear></ArticleCopyright><ArticleGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ArticleGrants></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1 Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>GuiZhao</GivenName><FamilyName>Liang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>ZeCong</GivenName><FamilyName>Chen</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>ShanBin</GivenName><FamilyName>Yang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Hu</GivenName><FamilyName>Mei</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Yuan</GivenName><FamilyName>Zhou</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Li</GivenName><FamilyName>Yang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Peng</GivenName><FamilyName>Zhou</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Eastern"><GivenName>ShengXi</GivenName><FamilyName>Yang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Mao</GivenName><FamilyName>Shu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>ChunYang</GivenName><FamilyName>Liao</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>ShiRong</GivenName><FamilyName>Wu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>GenRong</GivenName><FamilyName>Li</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Liu</GivenName><FamilyName>He</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>JianKun</GivenName><FamilyName>Gao</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>MengYu</GivenName><FamilyName>Gan</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>DeJing</GivenName><FamilyName>Li</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>GuoPing</GivenName><FamilyName>Chen</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>GuiXue</GivenName><FamilyName>Wang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Sha</GivenName><FamilyName>Long</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>JuHua</GivenName><FamilyName>Jing</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>XiaoLin</GivenName><FamilyName>Zheng</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>Hui</GivenName><FamilyName>Zeng</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>QiaoXia</GivenName><FamilyName>Zhang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>MengJun</GivenName><FamilyName>Zhang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>Qi</GivenName><FamilyName>Yang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>FeiFei</GivenName><FamilyName>Tian</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>JianBo</GivenName><FamilyName>Tong</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Eastern"><GivenName>JiaoNa</GivenName><FamilyName>Wang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>YongHong</GivenName><FamilyName>Liu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Eastern"><GivenName>Bo</GivenName><FamilyName>Li</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>LiangJia</GivenName><FamilyName>Qiu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>ShaoXi</GivenName><FamilyName>Cai</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Na</GivenName><FamilyName>Zhao</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Yan</GivenName><FamilyName>Yang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>XiaLi</GivenName><FamilyName>Su</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>Jian</GivenName><FamilyName>Song</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>MeiXia</GivenName><FamilyName>Chen</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>XueJiao</GivenName><FamilyName>Zhang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>JiaYing</GivenName><FamilyName>Sun</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>JingWei</GivenName><FamilyName>Li</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>GuoHua</GivenName><FamilyName>Chen</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff4"><AuthorName DisplayOrder="Eastern"><GivenName>Gang</GivenName><FamilyName>Chen</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>Jie</GivenName><FamilyName>Deng</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>ChuanYou</GivenName><FamilyName>Peng</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Eastern"><GivenName>WanPing</GivenName><FamilyName>Zhu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2 Aff3"><AuthorName DisplayOrder="Eastern"><GivenName>LuoNan</GivenName><FamilyName>Xu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>YuQuan</GivenName><FamilyName>Wu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>LiMin</GivenName><FamilyName>Liao</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>Zhi</GivenName><FamilyName>Li</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Eastern"><GivenName>Jun</GivenName><FamilyName>Li</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Eastern"><GivenName>DaJun</GivenName><FamilyName>Lu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Eastern"><GivenName>QinLiang</GivenName><FamilyName>Su</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>ZhengHu</GivenName><FamilyName>Huang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2"><AuthorName DisplayOrder="Eastern"><GivenName>Ping</GivenName><FamilyName>Zhou</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1 Aff2" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Eastern"><GivenName>ZhiLiang</GivenName><FamilyName>Li</FamilyName></AuthorName><Contact><Email>zlli-cqu@163.com</Email><Email>zlli2662@163.com</Email><Email>sdqdlgz@163.com</Email></Contact></Author><Affiliation ID="Aff1"><OrgDivision>College of Chemistry and Chemical Engineering</OrgDivision><OrgName>Chongqing University</OrgName><OrgAddress><City>Chongqing</City><Postcode>400044</Postcode><Country Code="CN">China</Country></OrgAddress></Affiliation><Affiliation ID="Aff2"><OrgName>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University</OrgName><OrgAddress><City>Chongqing</City><Postcode>400044</Postcode><Country Code="CN">China</Country></OrgAddress></Affiliation><Affiliation ID="Aff3"><OrgDivision>College of Bioengineering</OrgDivision><OrgName>Chongqing University</OrgName><OrgAddress><City>Chongqing</City><Postcode>400044</Postcode><Country Code="CN">China</Country></OrgAddress></Affiliation><Affiliation ID="Aff4"><OrgDivision>Technology Centre for Life Sciences and Biotechnology</OrgDivision><OrgName>Singapore Polytechnic</OrgName><OrgAddress><City>Singapore</City><Postcode>139651</Postcode><Country Code="SG">Singapore</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para>Total 200 properties related to structural characteristics were employed to represent structures of 400 HA coded proteins of influenza virus as training samples. Some recognition models for HA proteins of avian influenza virus (AIV) were developed using support vector machine (SVM) and linear discriminant analysis (LDA). The results obtained from LDA are as follows: the identification accuracy (<Emphasis Type="Italic">R</Emphasis><Subscript><Emphasis Type="Italic">ia</Emphasis></Subscript>) for training samples is 99.8% and <Emphasis Type="Italic">R</Emphasis><Subscript><Emphasis Type="Italic">ia</Emphasis></Subscript> by leave one out cross validation is 99.5%. Both <Emphasis Type="Italic">R</Emphasis><Subscript><Emphasis Type="Italic">ia</Emphasis></Subscript> of 99.8% for training samples and <Emphasis Type="Italic">R</Emphasis><Subscript><Emphasis Type="Italic">ia</Emphasis></Subscript> of 99.3% by leave one out cross validation are obtained using SVM model, respectively. External 200 HA proteins of influenza virus were used to validate the external predictive power of the resulting model. The external <Emphasis Type="Italic">R</Emphasis><Subscript><Emphasis Type="Italic">ia</Emphasis></Subscript> for them is 95.5% by LDA and 96.5% by SVM, respectively, which shows that HA proteins of AIVs are preferably recognized by SVM and LDA, and the performances by SVM are superior to those by LDA.</Para></Abstract><KeywordGroup Language="En"><Heading>Keywords</Heading><Keyword>avian influenza virus (AIV)</Keyword><Keyword>HA protein</Keyword><Keyword>support vector machine (SVM)</Keyword><Keyword>linear discriminant analysis (LDA)</Keyword></KeywordGroup><ArticleNote Type="Misc"><SimplePara>Supported by Foundations of National High Technology (863) Programme (Grant No. 2006AA02Z312), Innovative Group Programme for Graduates of Chongqing University, Science and Innovation Fund (Grant No. 200711C1A0010260), National 111 Programme Introducing Talents of Discipline to Universities (Grant No. 0507111106), Chongqing Municipality Basic and Applied Fundamental Science Fund (Grant No. 01-3-6), National Chunhui Project Foundation (Grant No. 99-4-4+3-7), State Key Laboratory of Chemo/Biosensing and Chemometrics Fund (Grant No. 2005012), Fok-Yingtung Educational Foundation (Grant No. 98-7-6)</SimplePara></ArticleNote></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Recognition for avian influenza virus proteins based on support vector machine and linear discriminant analysis</title></titleInfo><name type="personal"><namePart type="given">GuiZhao</namePart><namePart type="family">Liang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ZeCong</namePart><namePart type="family">Chen</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ShanBin</namePart><namePart type="family">Yang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hu</namePart><namePart type="family">Mei</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yuan</namePart><namePart type="family">Zhou</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Li</namePart><namePart type="family">Yang</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Peng</namePart><namePart type="family">Zhou</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ShengXi</namePart><namePart type="family">Yang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mao</namePart><namePart type="family">Shu</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ChunYang</namePart><namePart type="family">Liao</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ShiRong</namePart><namePart type="family">Wu</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GenRong</namePart><namePart type="family">Li</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Liu</namePart><namePart type="family">He</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JianKun</namePart><namePart type="family">Gao</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MengYu</namePart><namePart type="family">Gan</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DeJing</namePart><namePart type="family">Li</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GuoPing</namePart><namePart type="family">Chen</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GuiXue</namePart><namePart type="family">Wang</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sha</namePart><namePart type="family">Long</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JuHua</namePart><namePart type="family">Jing</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">XiaoLin</namePart><namePart type="family">Zheng</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hui</namePart><namePart type="family">Zeng</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">QiaoXia</namePart><namePart type="family">Zhang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MengJun</namePart><namePart type="family">Zhang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Qi</namePart><namePart type="family">Yang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FeiFei</namePart><namePart type="family">Tian</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JianBo</namePart><namePart type="family">Tong</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JiaoNa</namePart><namePart type="family">Wang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YongHong</namePart><namePart type="family">Liu</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Bo</namePart><namePart type="family">Li</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LiangJia</namePart><namePart type="family">Qiu</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ShaoXi</namePart><namePart type="family">Cai</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Na</namePart><namePart type="family">Zhao</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yan</namePart><namePart type="family">Yang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">XiaLi</namePart><namePart type="family">Su</namePart><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jian</namePart><namePart type="family">Song</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MeiXia</namePart><namePart type="family">Chen</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">XueJiao</namePart><namePart type="family">Zhang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JiaYing</namePart><namePart type="family">Sun</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JingWei</namePart><namePart type="family">Li</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GuoHua</namePart><namePart type="family">Chen</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gang</namePart><namePart type="family">Chen</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Technology Centre for Life Sciences and Biotechnology, Singapore Polytechnic, 139651, Singapore, Singapore</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jie</namePart><namePart type="family">Deng</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ChuanYou</namePart><namePart type="family">Peng</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WanPing</namePart><namePart type="family">Zhu</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LuoNan</namePart><namePart type="family">Xu</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>College of Bioengineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YuQuan</namePart><namePart type="family">Wu</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LiMin</namePart><namePart type="family">Liao</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Zhi</namePart><namePart type="family">Li</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jun</namePart><namePart type="family">Li</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DaJun</namePart><namePart type="family">Lu</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">QinLiang</namePart><namePart type="family">Su</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ZhengHu</namePart><namePart type="family">Huang</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ping</namePart><namePart type="family">Zhou</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal" displayLabel="corresp"><namePart type="given">ZhiLiang</namePart><namePart type="family">Li</namePart><affiliation>College of Chemistry and Chemical Engineering, Chongqing University, 400044, Chongqing, China</affiliation><affiliation>Key Laboratory for Biomechanics and Tissue Engineering under Ministry of Education at Chongqing University, 400044, Chongqing, China</affiliation><affiliation>E-mail: zlli-cqu@163.com</affiliation><affiliation>E-mail: zlli2662@163.com</affiliation><affiliation>E-mail: sdqdlgz@163.com</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Science in China Press; www.scichina.com</publisher><place><placeTerm type="text">Beijing</placeTerm></place><dateCreated encoding="w3cdtf">2005-11-27</dateCreated><dateIssued encoding="w3cdtf">2008-02-01</dateIssued><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Total 200 properties related to structural characteristics were employed to represent structures of 400 HA coded proteins of influenza virus as training samples. Some recognition models for HA proteins of avian influenza virus (AIV) were developed using support vector machine (SVM) and linear discriminant analysis (LDA). The results obtained from LDA are as follows: the identification accuracy (R ia ) for training samples is 99.8% and R ia by leave one out cross validation is 99.5%. Both R ia of 99.8% for training samples and R ia of 99.3% by leave one out cross validation are obtained using SVM model, respectively. External 200 HA proteins of influenza virus were used to validate the external predictive power of the resulting model. The external R ia for them is 95.5% by LDA and 96.5% by SVM, respectively, which shows that HA proteins of AIVs are preferably recognized by SVM and LDA, and the performances by SVM are superior to those by LDA.</abstract><subject lang="en"><genre>Keywords</genre><topic>avian influenza virus (AIV)</topic><topic>HA protein</topic><topic>support vector machine (SVM)</topic><topic>linear discriminant analysis (LDA)</topic></subject><relatedItem type="host"><titleInfo><title>Science in China Series B: Chemistry</title></titleInfo><titleInfo type="abbreviated"><title>Sci. China Ser. B-Chem.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>Springer</publisher><dateIssued encoding="w3cdtf">2008-02-01</dateIssued><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><subject><genre>Journal-Subject-Group</genre><topic authority="SpringerSubjectCodes" authorityURI="C">Chemistry</topic><topic authority="SpringerSubjectCodes" authorityURI="C00004">Chemistry/Food Science, general</topic></subject><identifier type="ISSN">1006-9291</identifier><identifier type="eISSN">1862-2771</identifier><identifier type="JournalID">11426</identifier><identifier type="JournalSPIN">31919487</identifier><identifier type="IssueArticleCount">13</identifier><identifier type="VolumeIssueCount">6</identifier><part><date>2008</date><detail type="volume"><number>51</number><caption>vol.</caption></detail><detail type="issue"><number>2</number><caption>no.</caption></detail><extent unit="pages"><start>166</start><end>170</end></extent></part><recordInfo><recordOrigin>Science in China Press, 2008</recordOrigin></recordInfo></relatedItem><identifier type="istex">6DA673A68B4BADCE4DCEAA9F13A3D9883CD3C48D</identifier><identifier type="ark">ark:/67375/VQC-9KHLS7DM-V</identifier><identifier type="DOI">10.1007/s11426-008-0006-7</identifier><identifier type="ArticleID">6</identifier><identifier type="ArticleID">s11426-008-0006-7</identifier><accessCondition type="use and reproduction" contentType="copyright">Science in China Press, 2008</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</recordContentSource><recordOrigin>Science in China Press, 2008</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-9KHLS7DM-V/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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