SrasV1, PubMed, Curation, bibRecord, 003361

Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.

Identifieur interne : 003361 ( PubMed/Curation ); précédent : 003360; suivant : 003362

Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.

Auteurs : J S M. Peiris [République populaire de Chine] ; C M Chu ; V C C. Cheng ; K S Chan ; I F N. Hung ; L L M. Poon ; K I Law ; B S F. Tang ; T Y W. Hon ; C S Chan ; K H Chan ; J S C. Ng ; B J Zheng ; W L Ng ; R W M. Lai ; Y. Guan ; K Y Yuen

Source :

Lancet (London, England) [ 0140-6736 ] ; 2003.

RBID : pubmed:12781535

Descripteurs français

KwdFr :
- Administration par voie orale, Adulte, Adulte d'âge moyen, Association amoxicilline-clavulanate de potassium (administration et posologie), Charge virale (), Complications de la grossesse et maladies infectieuses (), Complications de la grossesse et maladies infectieuses (diagnostic), Durée du séjour, Femelle, Flambées de maladies (), Grossesse, Humains, Mâle, Ofloxacine, Perfusions veineuses, Pharmacothérapie administrée en bolus, Poumon (imagerie diagnostique), Radiographie, Sujet âgé, Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Syndrome respiratoire aigu sévère (épidémiologie), Taux de survie, Virus du SRAS (isolement et purification), Études de suivi, Évolution de la maladie.
MESH :
- administration et posologie : Association amoxicilline-clavulanate de potassium.
- diagnostic : Complications de la grossesse et maladies infectieuses, Syndrome respiratoire aigu sévère.
- imagerie diagnostique : Poumon.
- isolement et purification : Virus du SRAS.
- traitement médicamenteux : Syndrome respiratoire aigu sévère.
- virologie : Syndrome respiratoire aigu sévère.
- épidémiologie : Syndrome respiratoire aigu sévère.
- Administration par voie orale, Adulte, Adulte d'âge moyen, Charge virale, Complications de la grossesse et maladies infectieuses, Durée du séjour, Femelle, Flambées de maladies, Grossesse, Humains, Mâle, Ofloxacine, Perfusions veineuses, Pharmacothérapie administrée en bolus, Radiographie, Sujet âgé, Taux de survie, Études de suivi, Évolution de la maladie.

English descriptors

KwdEn :
- Administration, Oral, Adult, Aged, Amoxicillin-Potassium Clavulanate Combination (administration & dosage), Disease Outbreaks (statistics & numerical data), Disease Progression, Female, Follow-Up Studies, Humans, Infusions, Intravenous, Length of Stay, Lung (diagnostic imaging), Male, Middle Aged, Ofloxacin, Pregnancy, Pregnancy Complications, Infectious (diagnosis), Pregnancy Complications, Infectious (therapy), Pulse Therapy, Drug, Radiography, SARS Virus (isolation & purification), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (virology), Survival Rate, Viral Load (statistics & numerical data).
MESH :
- chemical , administration & dosage : Amoxicillin-Potassium Clavulanate Combination.
- diagnosis : Pregnancy Complications, Infectious, Severe Acute Respiratory Syndrome.
- diagnostic imaging : Lung.
- drug therapy : Severe Acute Respiratory Syndrome.
- epidemiology : Severe Acute Respiratory Syndrome.
- isolation & purification : SARS Virus.
- statistics & numerical data : Disease Outbreaks, Viral Load.
- therapy : Pregnancy Complications, Infectious.
- virology : Severe Acute Respiratory Syndrome.
- Administration, Oral, Adult, Aged, Disease Progression, Female, Follow-Up Studies, Humans, Infusions, Intravenous, Length of Stay, Male, Middle Aged, Ofloxacin, Pregnancy, Pulse Therapy, Drug, Radiography, Survival Rate.

Abstract

We investigated the temporal progression of the clinical, radiological, and virological changes in a community outbreak of severe acute respiratory syndrome (SARS).

DOI: 10.1016/s0140-6736(03)13412-5
PubMed: 12781535

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<front><div type="abstract" xml:lang="en">We investigated the temporal progression of the clinical, radiological, and virological changes in a community outbreak of severe acute respiratory syndrome (SARS).</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12781535</PMID>
<DateCompleted><Year>2003</Year>
<Month>06</Month>
<Day>13</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0140-6736</ISSN>
<JournalIssue CitedMedium="Print"><Volume>361</Volume>
<Issue>9371</Issue>
<PubDate><Year>2003</Year>
<Month>May</Month>
<Day>24</Day>
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<Title>Lancet (London, England)</Title>
<ISOAbbreviation>Lancet</ISOAbbreviation>
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<ArticleTitle>Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.</ArticleTitle>
<Pagination><MedlinePgn>1767-72</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">We investigated the temporal progression of the clinical, radiological, and virological changes in a community outbreak of severe acute respiratory syndrome (SARS).</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We followed up 75 patients for 3 weeks managed with a standard treatment protocol of ribavirin and corticosteroids, and assessed the pattern of clinical disease, viral load, risk factors for poor clinical outcome, and the usefulness of virological diagnostic methods.</AbstractText>
<AbstractText Label="FINDINGS" NlmCategory="RESULTS">Fever and pneumonia initially improved but 64 (85%) patients developed recurrent fever after a mean of 8.9 (SD 3.1) days, 55 (73%) had watery diarrhoea after 7.5 (2.3) days, 60 (80%) had radiological worsening after 7.4 (2.2) days, and respiratory symptoms worsened in 34 (45%) after 8.6 (3.0) days. In 34 (45%) patients, improvement of initial pulmonary lesions was associated with appearance of new radiological lesions at other sites. Nine (12%) patients developed spontaneous pneumomediastinum and 15 (20%) developed acute respiratory distress syndrome (ARDS) in week 3. Quantitative reverse-transcriptase (RT) PCR of nasopharyngeal aspirates in 14 patients (four with ARDS) showed peak viral load at day 10, and at day 15 a load lower than at admission. Age and chronic hepatitis B virus infection treated with lamivudine were independent significant risk factors for progression to ARDS (p=0.001). SARS-associated coronavirus in faeces was seen on RT-PCR in 65 (97%) of 67 patients at day 14. The mean time to seroconversion was 20 days.</AbstractText>
<AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">The consistent clinical progression, shifting radiological infiltrates, and an inverted V viral-load profile suggest that worsening in week 2 is unrelated to uncontrolled viral replication but may be related to immunopathological damage.</AbstractText>
</Abstract>
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<ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1995-2005</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12671061</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Crit Care Med. 1985 Oct;13(10):818-29</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3928249</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Lancet. 2003 Apr 19;361(9366):1313-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12711461</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Am J Respir Crit Care Med. 1994 Mar;149(3 Pt 1):818-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7509706</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Clin Chem. 2003 Jun;49(6 Pt 1):953-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12765993</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Clin Radiol. 1989 Sep;40(5):463-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2551561</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Lancet. 2003 Apr 19;361(9366):1319-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12711465</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 1998 Apr 1;160(7):3487-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9531310</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1986-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12682352</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Pediatr Pulmonol. 1995 Jun;19(6):393-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7567221</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Am J Respir Cell Mol Biol. 2003 Feb;28(2):208-17</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12540488</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Infect Dis. 1986 Sep;154(3):443-7</Citation>
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Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.

Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study.

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