Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression.
Identifieur interne : 002B64 ( PubMed/Curation ); précédent : 002B63; suivant : 002B65Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression.
Auteurs : Yuchun Nie [République populaire de Chine] ; Peigang Wang ; Xuanling Shi ; Guangwen Wang ; Jian Chen ; Aihua Zheng ; Wei Wang ; Zai Wang ; Xiuxia Qu ; Min Luo ; Lei Tan ; Xijun Song ; Xiaolei Yin ; Jianguo Chen ; Mingxiao Ding ; Hongkui DengSource :
- Biochemical and biophysical research communications [ 0006-291X ] ; 2004.
Descripteurs français
- KwdFr :
- ADN recombiné (génétique), Animaux, Assemblage viral, Carboxypeptidases (génétique), Carboxypeptidases (physiologie), Cellules Vero, Chimère (génétique), Concentration en ions d'hydrogène, Expression des gènes, Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (génétique), Gènes viraux, Humains, Lignée cellulaire, Peptidyl-Dipeptidase A, Protéines de l'enveloppe virale (génétique), Récepteurs viraux (génétique), Récepteurs viraux (physiologie), Souris, Séquence nucléotidique, VIH (Virus de l'Immunodéficience Humaine) (génétique), Virulence (génétique), Virulence (physiologie), Virus du SRAS (génétique), Virus du SRAS (pathogénicité), Virus du SRAS (physiologie).
- MESH :
- génétique : ADN recombiné, Carboxypeptidases, Chimère, Glycoprotéines membranaires, Protéines de l'enveloppe virale, Récepteurs viraux, VIH (Virus de l'Immunodéficience Humaine), Virulence, Virus du SRAS.
- pathogénicité : Virus du SRAS.
- physiologie : Carboxypeptidases, Récepteurs viraux, Virulence, Virus du SRAS.
- Animaux, Assemblage viral, Cellules Vero, Concentration en ions d'hydrogène, Expression des gènes, Glycoprotéine de spicule des coronavirus, Gènes viraux, Humains, Lignée cellulaire, Peptidyl-Dipeptidase A, Souris, Séquence nucléotidique.
English descriptors
- KwdEn :
- Animals, Base Sequence, Carboxypeptidases (genetics), Carboxypeptidases (physiology), Cell Line, Chimera (genetics), Chlorocebus aethiops, DNA, Recombinant (genetics), Gene Expression, Genes, Viral, HIV (genetics), Humans, Hydrogen-Ion Concentration, Membrane Glycoproteins (genetics), Mice, Peptidyl-Dipeptidase A, Receptors, Virus (genetics), Receptors, Virus (physiology), SARS Virus (genetics), SARS Virus (pathogenicity), SARS Virus (physiology), Spike Glycoprotein, Coronavirus, Vero Cells, Viral Envelope Proteins (genetics), Virulence (genetics), Virulence (physiology), Virus Assembly.
- MESH :
- chemical , genetics : Carboxypeptidases, DNA, Recombinant, Membrane Glycoproteins, Receptors, Virus, Viral Envelope Proteins.
- chemical , physiology : Carboxypeptidases, Receptors, Virus.
- genetics : Chimera, HIV, SARS Virus, Virulence.
- pathogenicity : SARS Virus.
- physiology : SARS Virus, Virulence.
- Animals, Base Sequence, Cell Line, Chlorocebus aethiops, Gene Expression, Genes, Viral, Humans, Hydrogen-Ion Concentration, Mice, Peptidyl-Dipeptidase A, Spike Glycoprotein, Coronavirus, Vero Cells, Virus Assembly.
Abstract
Studies of SARS coronavirus (SARS-CoV)-the causative agent of severe acute respiratory syndrome (SARS)-have been hampered by its high transmission rate and the pathogenicity of this virus. To permit analysis of the host range and entry mechanism of SARS-CoV, we incorporated the humanized SARS-CoV spike (S) glycoprotein into HIV particles to generate a highly infectious SARS-CoV pseudotyped virus. The infection on Vero E6-a permissive cell line to SARS-CoV-could be neutralized by sera from convalescent SARS patients, and the entry was a pH-dependent process. With these highly infectious SARS-CoV pseudotypes, several cell lines derived from various tissues were revealed as susceptible to SARS-CoV, which were highly corresponding to the expression pattern of virus's receptor angiotensin-converting enzyme 2 (ACE2). In addition, we also demonstrated angiotensin 1 converting enzyme (ACE)-the homologue of ACE2 could not function as a receptor for SARS-CoV.
DOI: 10.1016/j.bbrc.2004.07.060
PubMed: 15358126
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002B64
Links to Exploration step
pubmed:15358126Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression.</title>
<author><name sortKey="Nie, Yuchun" sort="Nie, Yuchun" uniqKey="Nie Y" first="Yuchun" last="Nie">Yuchun Nie</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cell Biology and Genetics, College of Life Sciences, Peking University, Beijing 100871, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Cell Biology and Genetics, College of Life Sciences, Peking University, Beijing 100871</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Peigang" sort="Wang, Peigang" uniqKey="Wang P" first="Peigang" last="Wang">Peigang Wang</name>
</author>
<author><name sortKey="Shi, Xuanling" sort="Shi, Xuanling" uniqKey="Shi X" first="Xuanling" last="Shi">Xuanling Shi</name>
</author>
<author><name sortKey="Wang, Guangwen" sort="Wang, Guangwen" uniqKey="Wang G" first="Guangwen" last="Wang">Guangwen Wang</name>
</author>
<author><name sortKey="Chen, Jian" sort="Chen, Jian" uniqKey="Chen J" first="Jian" last="Chen">Jian Chen</name>
</author>
<author><name sortKey="Zheng, Aihua" sort="Zheng, Aihua" uniqKey="Zheng A" first="Aihua" last="Zheng">Aihua Zheng</name>
</author>
<author><name sortKey="Wang, Wei" sort="Wang, Wei" uniqKey="Wang W" first="Wei" last="Wang">Wei Wang</name>
</author>
<author><name sortKey="Wang, Zai" sort="Wang, Zai" uniqKey="Wang Z" first="Zai" last="Wang">Zai Wang</name>
</author>
<author><name sortKey="Qu, Xiuxia" sort="Qu, Xiuxia" uniqKey="Qu X" first="Xiuxia" last="Qu">Xiuxia Qu</name>
</author>
<author><name sortKey="Luo, Min" sort="Luo, Min" uniqKey="Luo M" first="Min" last="Luo">Min Luo</name>
</author>
<author><name sortKey="Tan, Lei" sort="Tan, Lei" uniqKey="Tan L" first="Lei" last="Tan">Lei Tan</name>
</author>
<author><name sortKey="Song, Xijun" sort="Song, Xijun" uniqKey="Song X" first="Xijun" last="Song">Xijun Song</name>
</author>
<author><name sortKey="Yin, Xiaolei" sort="Yin, Xiaolei" uniqKey="Yin X" first="Xiaolei" last="Yin">Xiaolei Yin</name>
</author>
<author><name sortKey="Chen, Jianguo" sort="Chen, Jianguo" uniqKey="Chen J" first="Jianguo" last="Chen">Jianguo Chen</name>
</author>
<author><name sortKey="Ding, Mingxiao" sort="Ding, Mingxiao" uniqKey="Ding M" first="Mingxiao" last="Ding">Mingxiao Ding</name>
</author>
<author><name sortKey="Deng, Hongkui" sort="Deng, Hongkui" uniqKey="Deng H" first="Hongkui" last="Deng">Hongkui Deng</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2004">2004</date>
<idno type="RBID">pubmed:15358126</idno>
<idno type="pmid">15358126</idno>
<idno type="doi">10.1016/j.bbrc.2004.07.060</idno>
<idno type="wicri:Area/PubMed/Corpus">002B64</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002B64</idno>
<idno type="wicri:Area/PubMed/Curation">002B64</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002B64</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression.</title>
<author><name sortKey="Nie, Yuchun" sort="Nie, Yuchun" uniqKey="Nie Y" first="Yuchun" last="Nie">Yuchun Nie</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cell Biology and Genetics, College of Life Sciences, Peking University, Beijing 100871, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Cell Biology and Genetics, College of Life Sciences, Peking University, Beijing 100871</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wang, Peigang" sort="Wang, Peigang" uniqKey="Wang P" first="Peigang" last="Wang">Peigang Wang</name>
</author>
<author><name sortKey="Shi, Xuanling" sort="Shi, Xuanling" uniqKey="Shi X" first="Xuanling" last="Shi">Xuanling Shi</name>
</author>
<author><name sortKey="Wang, Guangwen" sort="Wang, Guangwen" uniqKey="Wang G" first="Guangwen" last="Wang">Guangwen Wang</name>
</author>
<author><name sortKey="Chen, Jian" sort="Chen, Jian" uniqKey="Chen J" first="Jian" last="Chen">Jian Chen</name>
</author>
<author><name sortKey="Zheng, Aihua" sort="Zheng, Aihua" uniqKey="Zheng A" first="Aihua" last="Zheng">Aihua Zheng</name>
</author>
<author><name sortKey="Wang, Wei" sort="Wang, Wei" uniqKey="Wang W" first="Wei" last="Wang">Wei Wang</name>
</author>
<author><name sortKey="Wang, Zai" sort="Wang, Zai" uniqKey="Wang Z" first="Zai" last="Wang">Zai Wang</name>
</author>
<author><name sortKey="Qu, Xiuxia" sort="Qu, Xiuxia" uniqKey="Qu X" first="Xiuxia" last="Qu">Xiuxia Qu</name>
</author>
<author><name sortKey="Luo, Min" sort="Luo, Min" uniqKey="Luo M" first="Min" last="Luo">Min Luo</name>
</author>
<author><name sortKey="Tan, Lei" sort="Tan, Lei" uniqKey="Tan L" first="Lei" last="Tan">Lei Tan</name>
</author>
<author><name sortKey="Song, Xijun" sort="Song, Xijun" uniqKey="Song X" first="Xijun" last="Song">Xijun Song</name>
</author>
<author><name sortKey="Yin, Xiaolei" sort="Yin, Xiaolei" uniqKey="Yin X" first="Xiaolei" last="Yin">Xiaolei Yin</name>
</author>
<author><name sortKey="Chen, Jianguo" sort="Chen, Jianguo" uniqKey="Chen J" first="Jianguo" last="Chen">Jianguo Chen</name>
</author>
<author><name sortKey="Ding, Mingxiao" sort="Ding, Mingxiao" uniqKey="Ding M" first="Mingxiao" last="Ding">Mingxiao Ding</name>
</author>
<author><name sortKey="Deng, Hongkui" sort="Deng, Hongkui" uniqKey="Deng H" first="Hongkui" last="Deng">Hongkui Deng</name>
</author>
</analytic>
<series><title level="j">Biochemical and biophysical research communications</title>
<idno type="ISSN">0006-291X</idno>
<imprint><date when="2004" type="published">2004</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Base Sequence</term>
<term>Carboxypeptidases (genetics)</term>
<term>Carboxypeptidases (physiology)</term>
<term>Cell Line</term>
<term>Chimera (genetics)</term>
<term>Chlorocebus aethiops</term>
<term>DNA, Recombinant (genetics)</term>
<term>Gene Expression</term>
<term>Genes, Viral</term>
<term>HIV (genetics)</term>
<term>Humans</term>
<term>Hydrogen-Ion Concentration</term>
<term>Membrane Glycoproteins (genetics)</term>
<term>Mice</term>
<term>Peptidyl-Dipeptidase A</term>
<term>Receptors, Virus (genetics)</term>
<term>Receptors, Virus (physiology)</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (pathogenicity)</term>
<term>SARS Virus (physiology)</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Vero Cells</term>
<term>Viral Envelope Proteins (genetics)</term>
<term>Virulence (genetics)</term>
<term>Virulence (physiology)</term>
<term>Virus Assembly</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>ADN recombiné (génétique)</term>
<term>Animaux</term>
<term>Assemblage viral</term>
<term>Carboxypeptidases (génétique)</term>
<term>Carboxypeptidases (physiologie)</term>
<term>Cellules Vero</term>
<term>Chimère (génétique)</term>
<term>Concentration en ions d'hydrogène</term>
<term>Expression des gènes</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Glycoprotéines membranaires (génétique)</term>
<term>Gènes viraux</term>
<term>Humains</term>
<term>Lignée cellulaire</term>
<term>Peptidyl-Dipeptidase A</term>
<term>Protéines de l'enveloppe virale (génétique)</term>
<term>Récepteurs viraux (génétique)</term>
<term>Récepteurs viraux (physiologie)</term>
<term>Souris</term>
<term>Séquence nucléotidique</term>
<term>VIH (Virus de l'Immunodéficience Humaine) (génétique)</term>
<term>Virulence (génétique)</term>
<term>Virulence (physiologie)</term>
<term>Virus du SRAS (génétique)</term>
<term>Virus du SRAS (pathogénicité)</term>
<term>Virus du SRAS (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Carboxypeptidases</term>
<term>DNA, Recombinant</term>
<term>Membrane Glycoproteins</term>
<term>Receptors, Virus</term>
<term>Viral Envelope Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Carboxypeptidases</term>
<term>Receptors, Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Chimera</term>
<term>HIV</term>
<term>SARS Virus</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ADN recombiné</term>
<term>Carboxypeptidases</term>
<term>Chimère</term>
<term>Glycoprotéines membranaires</term>
<term>Protéines de l'enveloppe virale</term>
<term>Récepteurs viraux</term>
<term>VIH (Virus de l'Immunodéficience Humaine)</term>
<term>Virulence</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Carboxypeptidases</term>
<term>Récepteurs viraux</term>
<term>Virulence</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>SARS Virus</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Base Sequence</term>
<term>Cell Line</term>
<term>Chlorocebus aethiops</term>
<term>Gene Expression</term>
<term>Genes, Viral</term>
<term>Humans</term>
<term>Hydrogen-Ion Concentration</term>
<term>Mice</term>
<term>Peptidyl-Dipeptidase A</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Vero Cells</term>
<term>Virus Assembly</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Assemblage viral</term>
<term>Cellules Vero</term>
<term>Concentration en ions d'hydrogène</term>
<term>Expression des gènes</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Gènes viraux</term>
<term>Humains</term>
<term>Lignée cellulaire</term>
<term>Peptidyl-Dipeptidase A</term>
<term>Souris</term>
<term>Séquence nucléotidique</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Studies of SARS coronavirus (SARS-CoV)-the causative agent of severe acute respiratory syndrome (SARS)-have been hampered by its high transmission rate and the pathogenicity of this virus. To permit analysis of the host range and entry mechanism of SARS-CoV, we incorporated the humanized SARS-CoV spike (S) glycoprotein into HIV particles to generate a highly infectious SARS-CoV pseudotyped virus. The infection on Vero E6-a permissive cell line to SARS-CoV-could be neutralized by sera from convalescent SARS patients, and the entry was a pH-dependent process. With these highly infectious SARS-CoV pseudotypes, several cell lines derived from various tissues were revealed as susceptible to SARS-CoV, which were highly corresponding to the expression pattern of virus's receptor angiotensin-converting enzyme 2 (ACE2). In addition, we also demonstrated angiotensin 1 converting enzyme (ACE)-the homologue of ACE2 could not function as a receptor for SARS-CoV.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15358126</PMID>
<DateCompleted><Year>2004</Year>
<Month>10</Month>
<Day>14</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0006-291X</ISSN>
<JournalIssue CitedMedium="Print"><Volume>321</Volume>
<Issue>4</Issue>
<PubDate><Year>2004</Year>
<Month>Sep</Month>
<Day>03</Day>
</PubDate>
</JournalIssue>
<Title>Biochemical and biophysical research communications</Title>
<ISOAbbreviation>Biochem. Biophys. Res. Commun.</ISOAbbreviation>
</Journal>
<ArticleTitle>Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression.</ArticleTitle>
<Pagination><MedlinePgn>994-1000</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Studies of SARS coronavirus (SARS-CoV)-the causative agent of severe acute respiratory syndrome (SARS)-have been hampered by its high transmission rate and the pathogenicity of this virus. To permit analysis of the host range and entry mechanism of SARS-CoV, we incorporated the humanized SARS-CoV spike (S) glycoprotein into HIV particles to generate a highly infectious SARS-CoV pseudotyped virus. The infection on Vero E6-a permissive cell line to SARS-CoV-could be neutralized by sera from convalescent SARS patients, and the entry was a pH-dependent process. With these highly infectious SARS-CoV pseudotypes, several cell lines derived from various tissues were revealed as susceptible to SARS-CoV, which were highly corresponding to the expression pattern of virus's receptor angiotensin-converting enzyme 2 (ACE2). In addition, we also demonstrated angiotensin 1 converting enzyme (ACE)-the homologue of ACE2 could not function as a receptor for SARS-CoV.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nie</LastName>
<ForeName>Yuchun</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Cell Biology and Genetics, College of Life Sciences, Peking University, Beijing 100871, PR China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Peigang</ForeName>
<Initials>P</Initials>
</Author>
<Author ValidYN="Y"><LastName>Shi</LastName>
<ForeName>Xuanling</ForeName>
<Initials>X</Initials>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Guangwen</ForeName>
<Initials>G</Initials>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Jian</ForeName>
<Initials>J</Initials>
</Author>
<Author ValidYN="Y"><LastName>Zheng</LastName>
<ForeName>Aihua</ForeName>
<Initials>A</Initials>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Wei</ForeName>
<Initials>W</Initials>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Zai</ForeName>
<Initials>Z</Initials>
</Author>
<Author ValidYN="Y"><LastName>Qu</LastName>
<ForeName>Xiuxia</ForeName>
<Initials>X</Initials>
</Author>
<Author ValidYN="Y"><LastName>Luo</LastName>
<ForeName>Min</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Tan</LastName>
<ForeName>Lei</ForeName>
<Initials>L</Initials>
</Author>
<Author ValidYN="Y"><LastName>Song</LastName>
<ForeName>Xijun</ForeName>
<Initials>X</Initials>
</Author>
<Author ValidYN="Y"><LastName>Yin</LastName>
<ForeName>Xiaolei</ForeName>
<Initials>X</Initials>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Jianguo</ForeName>
<Initials>J</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ding</LastName>
<ForeName>Mingxiao</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Deng</LastName>
<ForeName>Hongkui</ForeName>
<Initials>H</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Biochem Biophys Res Commun</MedlineTA>
<NlmUniqueID>0372516</NlmUniqueID>
<ISSNLinking>0006-291X</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D004274">DNA, Recombinant</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D008562">Membrane Glycoproteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D011991">Receptors, Virus</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D064370">Spike Glycoprotein, Coronavirus</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014759">Viral Envelope Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C578557">spike glycoprotein, SARS-CoV</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.-</RegistryNumber>
<NameOfSubstance UI="D002268">Carboxypeptidases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.15.1</RegistryNumber>
<NameOfSubstance UI="D007703">Peptidyl-Dipeptidase A</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.17.-</RegistryNumber>
<NameOfSubstance UI="C413524">angiotensin converting enzyme 2</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001483" MajorTopicYN="N">Base Sequence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002268" MajorTopicYN="N">Carboxypeptidases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002460" MajorTopicYN="N">Cell Line</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002678" MajorTopicYN="N">Chimera</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002522" MajorTopicYN="N">Chlorocebus aethiops</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004274" MajorTopicYN="N">DNA, Recombinant</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015870" MajorTopicYN="N">Gene Expression</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005814" MajorTopicYN="N">Genes, Viral</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006678" MajorTopicYN="N">HIV</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006863" MajorTopicYN="N">Hydrogen-Ion Concentration</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008562" MajorTopicYN="N">Membrane Glycoproteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007703" MajorTopicYN="N">Peptidyl-Dipeptidase A</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011991" MajorTopicYN="N">Receptors, Virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D064370" MajorTopicYN="N">Spike Glycoprotein, Coronavirus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014709" MajorTopicYN="N">Vero Cells</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014759" MajorTopicYN="N">Viral Envelope Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014774" MajorTopicYN="N">Virulence</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019065" MajorTopicYN="N">Virus Assembly</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2004</Year>
<Month>07</Month>
<Day>02</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2004</Year>
<Month>9</Month>
<Day>11</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2004</Year>
<Month>10</Month>
<Day>16</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2004</Year>
<Month>9</Month>
<Day>11</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">15358126</ArticleId>
<ArticleId IdType="doi">10.1016/j.bbrc.2004.07.060</ArticleId>
<ArticleId IdType="pii">S0006-291X(04)01556-6</ArticleId>
<ArticleId IdType="pmc">PMC7092805</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Biochem J. 1993 Feb 15;290 ( Pt 1):33-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8382480</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>FEBS Lett. 2002 Dec 4;532(1-2):107-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12459472</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Zhonghua Bing Li Xue Za Zhi. 2003 Jun;32(3):205-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12882682</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Biochem Biophys Res Commun. 1978 Aug 14;83(3):843-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">213075</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Chin Med J (Engl). 2003 Jun;116(6):827-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12877788</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4240-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15010527</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1998 Apr;72(4):3155-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9525641</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nature. 1996 Jun 20;381(6584):661-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8649511</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nature. 1997 Jul 17;388(6639):296-300</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9230441</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2004 Jun;78(11):5642-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15140961</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Lancet. 2003 Jul 26;362(9380):263-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12892955</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1994 Aug;68(8):4879-89</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8035486</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1953-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690092</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Adv Exp Med Biol. 1984;173:25-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6331116</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nature. 2003 Nov 27;426(6965):450-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14647384</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1967-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690091</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 1995 Feb 1;206(2):935-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7531918</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Biochem Biophys Res Commun. 2004 Mar 5;315(2):439-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14766227</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Cell. 2001 Jul 13;106(1):117-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11461707</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Gastroenterology. 2003 Oct;125(4):1011-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14517783</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Gen Virol. 2002 Jul;83(Pt 7):1535-1545</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12075072</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nature. 2003 May 15;423(6937):240</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12748632</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Science. 2003 May 30;300(5624):1394-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12730500</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Avian Dis. 2001 Apr-Jun;45(2):366-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11417816</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1999 Sep;73(9):7607-18</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10438851</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1992 Dec;66(12):7374-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1331528</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1998 Dec;72(12):9628-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9811696</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1991 Jan;65(1):162-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1845882</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Jun;35(6):587-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12796822</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002B64 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 002B64 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:15358126 |texte= Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:15358126" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |