SARS coronavirus E protein forms cation-selective ion channels.
Identifieur interne : 002A60 ( PubMed/Curation ); précédent : 002A59; suivant : 002A61SARS coronavirus E protein forms cation-selective ion channels.
Auteurs : Lauren Wilson [Australie] ; Carolyn Mckinlay ; Peter Gage ; Gary EwartSource :
- Virology [ 0042-6822 ] ; 2004.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Peptide Fragments, Viral Envelope Proteins.
- chemical , physiology : Ion Channels, Viral Envelope Proteins.
- physiology : SARS Virus.
- Amino Acid Sequence, Lipid Bilayers, Membrane Potentials, Molecular Sequence Data.
Abstract
Severe Acute Respiratory Syndrome (SARS) is caused by a novel coronavirus (SARS-CoV). Coronaviruses including SARS-CoV encode an envelope (E) protein, a small, hydrophobic membrane protein. We report that, in planar lipid bilayers, synthetic peptides corresponding to the SARS-CoV E protein forms ion channels that are more permeable to monovalent cations than to monovalent anions. Affinity-purified polyclonal antibodies recognizing the N-terminal 19 residues of SARS-CoV E protein were used to establish the specificity of channel formation by inhibiting the ion currents generated in the presence of the E protein peptides.
DOI: 10.1016/j.virol.2004.09.033
PubMed: 15527857
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002A60
Links to Exploration step
pubmed:15527857Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">SARS coronavirus E protein forms cation-selective ion channels.</title><author><name sortKey="Wilson, Lauren" sort="Wilson, Lauren" uniqKey="Wilson L" first="Lauren" last="Wilson">Lauren Wilson</name><affiliation wicri:level="1"><nlm:affiliation>Medical School, Frank Fenner Building 42, ANU, Canberra, ACT 2601, Australia. lwilson@biotron.com.au</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Medical School, Frank Fenner Building 42, ANU, Canberra, ACT 2601</wicri:regionArea></affiliation></author><author><name sortKey="Mckinlay, Carolyn" sort="Mckinlay, Carolyn" uniqKey="Mckinlay C" first="Carolyn" last="Mckinlay">Carolyn Mckinlay</name></author><author><name sortKey="Gage, Peter" sort="Gage, Peter" uniqKey="Gage P" first="Peter" last="Gage">Peter Gage</name></author><author><name sortKey="Ewart, Gary" sort="Ewart, Gary" uniqKey="Ewart G" first="Gary" last="Ewart">Gary Ewart</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2004">2004</date><idno type="RBID">pubmed:15527857</idno><idno type="pmid">15527857</idno><idno type="doi">10.1016/j.virol.2004.09.033</idno><idno type="wicri:Area/PubMed/Corpus">002A60</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002A60</idno><idno type="wicri:Area/PubMed/Curation">002A60</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002A60</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">SARS coronavirus E protein forms cation-selective ion channels.</title><author><name sortKey="Wilson, Lauren" sort="Wilson, Lauren" uniqKey="Wilson L" first="Lauren" last="Wilson">Lauren Wilson</name><affiliation wicri:level="1"><nlm:affiliation>Medical School, Frank Fenner Building 42, ANU, Canberra, ACT 2601, Australia. lwilson@biotron.com.au</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Medical School, Frank Fenner Building 42, ANU, Canberra, ACT 2601</wicri:regionArea></affiliation></author><author><name sortKey="Mckinlay, Carolyn" sort="Mckinlay, Carolyn" uniqKey="Mckinlay C" first="Carolyn" last="Mckinlay">Carolyn Mckinlay</name></author><author><name sortKey="Gage, Peter" sort="Gage, Peter" uniqKey="Gage P" first="Peter" last="Gage">Peter Gage</name></author><author><name sortKey="Ewart, Gary" sort="Ewart, Gary" uniqKey="Ewart G" first="Gary" last="Ewart">Gary Ewart</name></author></analytic><series><title level="j">Virology</title><idno type="ISSN">0042-6822</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino Acid Sequence</term><term>Ion Channels (physiology)</term><term>Lipid Bilayers</term><term>Membrane Potentials</term><term>Molecular Sequence Data</term><term>Peptide Fragments (chemistry)</term><term>SARS Virus (physiology)</term><term>Viral Envelope Proteins (chemistry)</term><term>Viral Envelope Proteins (physiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Canaux ioniques (physiologie)</term><term>Données de séquences moléculaires</term><term>Double couche lipidique</term><term>Fragments peptidiques ()</term><term>Potentiels de membrane</term><term>Protéines de l'enveloppe virale ()</term><term>Protéines de l'enveloppe virale (physiologie)</term><term>Séquence d'acides aminés</term><term>Virus du SRAS (physiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Peptide Fragments</term><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Ion Channels</term><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Canaux ioniques</term><term>Protéines de l'enveloppe virale</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term><term>Lipid Bilayers</term><term>Membrane Potentials</term><term>Molecular Sequence Data</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Données de séquences moléculaires</term><term>Double couche lipidique</term><term>Fragments peptidiques</term><term>Potentiels de membrane</term><term>Protéines de l'enveloppe virale</term><term>Séquence d'acides aminés</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Severe Acute Respiratory Syndrome (SARS) is caused by a novel coronavirus (SARS-CoV). Coronaviruses including SARS-CoV encode an envelope (E) protein, a small, hydrophobic membrane protein. We report that, in planar lipid bilayers, synthetic peptides corresponding to the SARS-CoV E protein forms ion channels that are more permeable to monovalent cations than to monovalent anions. Affinity-purified polyclonal antibodies recognizing the N-terminal 19 residues of SARS-CoV E protein were used to establish the specificity of channel formation by inhibiting the ion currents generated in the presence of the E protein peptides.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15527857</PMID><DateCompleted><Year>2005</Year><Month>03</Month><Day>24</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>03</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0042-6822</ISSN><JournalIssue CitedMedium="Print"><Volume>330</Volume><Issue>1</Issue><PubDate><Year>2004</Year><Month>Dec</Month><Day>05</Day></PubDate></JournalIssue><Title>Virology</Title><ISOAbbreviation>Virology</ISOAbbreviation></Journal><ArticleTitle>SARS coronavirus E protein forms cation-selective ion channels.</ArticleTitle><Pagination><MedlinePgn>322-31</MedlinePgn></Pagination><Abstract><AbstractText>Severe Acute Respiratory Syndrome (SARS) is caused by a novel coronavirus (SARS-CoV). Coronaviruses including SARS-CoV encode an envelope (E) protein, a small, hydrophobic membrane protein. We report that, in planar lipid bilayers, synthetic peptides corresponding to the SARS-CoV E protein forms ion channels that are more permeable to monovalent cations than to monovalent anions. Affinity-purified polyclonal antibodies recognizing the N-terminal 19 residues of SARS-CoV E protein were used to establish the specificity of channel formation by inhibiting the ion currents generated in the presence of the E protein peptides.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wilson</LastName><ForeName>Lauren</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Medical School, Frank Fenner Building 42, ANU, Canberra, ACT 2601, Australia. lwilson@biotron.com.au</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McKinlay</LastName><ForeName>Carolyn</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Gage</LastName><ForeName>Peter</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Ewart</LastName><ForeName>Gary</ForeName><Initials>G</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Virology</MedlineTA><NlmUniqueID>0110674</NlmUniqueID><ISSNLinking>0042-6822</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007473">Ion Channels</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008051">Lipid Bilayers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010446">Peptide Fragments</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014759">Viral Envelope Proteins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000595" MajorTopicYN="N">Amino Acid Sequence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007473" MajorTopicYN="N">Ion Channels</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008051" MajorTopicYN="N">Lipid Bilayers</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008564" MajorTopicYN="N">Membrane Potentials</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008969" MajorTopicYN="N">Molecular Sequence Data</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010446" MajorTopicYN="N">Peptide Fragments</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014759" MajorTopicYN="N">Viral Envelope Proteins</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2004</Year><Month>06</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2004</Year><Month>07</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2004</Year><Month>09</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2004</Year><Month>11</Month><Day>6</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2005</Year><Month>3</Month><Day>25</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2004</Year><Month>11</Month><Day>6</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">15527857</ArticleId><ArticleId IdType="pii">S0042-6822(04)00644-0</ArticleId><ArticleId IdType="doi">10.1016/j.virol.2004.09.033</ArticleId><ArticleId IdType="pmc">PMC7111769</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>FEBS Lett. 1996 Nov 25;398(1):12-8</Citation><ArticleIdList><ArticleId IdType="pubmed">8946945</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7381-5</Citation><ArticleIdList><ArticleId IdType="pubmed">8346259</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Cell Biol. 1994 Jan;124(1-2):55-70</Citation><ArticleIdList><ArticleId IdType="pubmed">8294506</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Cell Biol. 1996 May;133(4):733-47</Citation><ArticleIdList><ArticleId IdType="pubmed">8666660</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1996 Feb;70(2):809-19</Citation><ArticleIdList><ArticleId IdType="pubmed">8551619</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1967-76</Citation><ArticleIdList><ArticleId IdType="pubmed">12690091</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>EMBO J. 1996 Apr 15;15(8):2020-8</Citation><ArticleIdList><ArticleId IdType="pubmed">8617249</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 1994 Jul;202(1):287-93</Citation><ArticleIdList><ArticleId IdType="pubmed">7516598</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1998 Oct;72(10):7885-94</Citation><ArticleIdList><ArticleId IdType="pubmed">9733825</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1992 Aug;66(8):5119-26</Citation><ArticleIdList><ArticleId IdType="pubmed">1629967</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 1992 Sep;190(1):485-9</Citation><ArticleIdList><ArticleId IdType="pubmed">1382343</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Biol Chem. 2004 Apr 23;279(17):17483-9</Citation><ArticleIdList><ArticleId IdType="pubmed">14752102</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 1991 Apr 15;88(8):3195-9</Citation><ArticleIdList><ArticleId IdType="pubmed">2014240</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1998 Nov;72(11):8636-43</Citation><ArticleIdList><ArticleId IdType="pubmed">9765403</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Mol Immunol. 1991 Jun;28(6):623-30</Citation><ArticleIdList><ArticleId IdType="pubmed">1861679</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1953-66</Citation><ArticleIdList><ArticleId IdType="pubmed">12690092</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 1996 Apr 1;218(1):52-60</Citation><ArticleIdList><ArticleId IdType="pubmed">8615041</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):111-5</Citation><ArticleIdList><ArticleId IdType="pubmed">8552585</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1993 Aug;67(8):5056-61</Citation><ArticleIdList><ArticleId IdType="pubmed">8331740</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Membr Biol. 1996 Mar;150(2):127-32</Citation><ArticleIdList><ArticleId IdType="pubmed">8661776</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 2001 Jan 20;279(2):371-4</Citation><ArticleIdList><ArticleId IdType="pubmed">11162792</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Membr Biol. 1994 Oct;142(1):117-26</Citation><ArticleIdList><ArticleId IdType="pubmed">7535851</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Acta Pharmacol Sin. 2003 Jun;24(6):505-11</Citation><ArticleIdList><ArticleId IdType="pubmed">12791175</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Biol Chem. 2000 Oct 6;275(40):31038-50</Citation><ArticleIdList><ArticleId IdType="pubmed">10913133</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Med Primatol. 1994 Feb-May;23(2-3):146-50</Citation><ArticleIdList><ArticleId IdType="pubmed">7966229</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1994 Oct;68(10):6523-34</Citation><ArticleIdList><ArticleId IdType="pubmed">8083990</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Biochem Biophys Res Commun. 2004 Jun 11;318(4):833-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15147946</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Mol Biol. 2004 Aug 13;341(3):769-79</Citation><ArticleIdList><ArticleId IdType="pubmed">15288785</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Biochim Biophys Acta. 2002 Mar 19;1561(1):27-45</Citation><ArticleIdList><ArticleId IdType="pubmed">11988179</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 2001 Jan 5;279(1):201-9</Citation><ArticleIdList><ArticleId IdType="pubmed">11145902</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 2002 Nov;76(22):11518-29</Citation><ArticleIdList><ArticleId IdType="pubmed">12388713</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Arch Virol. 2003 Nov;148(11):2207-35</Citation><ArticleIdList><ArticleId IdType="pubmed">14579179</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>FEBS Lett. 2003 Jan 30;535(1-3):34-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12560074</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Cell. 1992 May 1;69(3):517-28</Citation><ArticleIdList><ArticleId IdType="pubmed">1374685</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1996 Oct;70(10):7108-15</Citation><ArticleIdList><ArticleId IdType="pubmed">8794357</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 2001 Dec 20;291(2):198-207</Citation><ArticleIdList><ArticleId IdType="pubmed">11878889</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1998 Jun;72(6):5189-97</Citation><ArticleIdList><ArticleId IdType="pubmed">9573291</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 2000 Apr 10;269(2):305-12</Citation><ArticleIdList><ArticleId IdType="pubmed">10753709</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 1999 Oct 25;263(2):265-72</Citation><ArticleIdList><ArticleId IdType="pubmed">10544100</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Biol Chem. 2002 Dec 6;277(49):46923-31</Citation><ArticleIdList><ArticleId IdType="pubmed">12228229</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>FEBS Lett. 2003 Sep 18;552(1):28-34</Citation><ArticleIdList><ArticleId IdType="pubmed">12972148</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Eur J Cell Biol. 1984 Mar;33(2):281-93</Citation><ArticleIdList><ArticleId IdType="pubmed">6325194</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>FEBS Lett. 2004 Jan 16;557(1-3):99-103</Citation><ArticleIdList><ArticleId IdType="pubmed">14741348</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 2000 May;74(9):4319-26</Citation><ArticleIdList><ArticleId IdType="pubmed">10756047</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Mol Cell. 2004 Apr 23;14(2):259-67</Citation><ArticleIdList><ArticleId IdType="pubmed">15099524</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 1990 Feb;64(2):621-9</Citation><ArticleIdList><ArticleId IdType="pubmed">2404139</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2003 May 13;100(10):6104-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12719519</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>FEBS Lett. 2003 Sep 18;552(1):47-53</Citation><ArticleIdList><ArticleId IdType="pubmed">12972151</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Dev Cell. 2003 Jul;5(1):175-84</Citation><ArticleIdList><ArticleId IdType="pubmed">12852861</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Lancet. 2003 Apr 19;361(9366):1319-25</Citation><ArticleIdList><ArticleId IdType="pubmed">12711465</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14336-41</Citation><ArticleIdList><ArticleId IdType="pubmed">10588706</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 2003 Apr;77(8):4597-608</Citation><ArticleIdList><ArticleId IdType="pubmed">12663766</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002A60 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 002A60 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:15527857
|texte= SARS coronavirus E protein forms cation-selective ion channels.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:15527857" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |