SrasV1, PubMed, Curation, bibRecord, 002983

The E protein is a multifunctional membrane protein of SARS-CoV.

Identifieur interne : 002983 ( PubMed/Curation ); précédent : 002982; suivant : 002984

The E protein is a multifunctional membrane protein of SARS-CoV.

Auteurs : Qingfa Wu [République populaire de Chine] ; Yilin Zhang ; Hong Lü ; Jing Wang ; Ximiao He ; Yong Liu ; Chen Ye ; Wei Lin ; Jianfei Hu ; Jia Ji ; Jing Xu ; Jie Ye ; Yongwu Hu ; Wenjun Chen ; Songgang Li ; Jun Wang ; Jian Wang ; Shengli Bi ; Huanming Yang

Source :

Genomics, proteomics & bioinformatics [ 1672-0229 ] ; 2003.

RBID : pubmed:15626343

Descripteurs français

English descriptors

KwdEn :
- Amino Acid Sequence, Base Sequence, Cluster Analysis, Codon (genetics), Gene Components, Genome, Viral, Membrane Glycoproteins (metabolism), Membrane Proteins (genetics), Membrane Proteins (metabolism), Molecular Sequence Data, Phylogeny, Protein Conformation, SARS Virus (genetics), Sequence Alignment, Sequence Analysis, DNA, Sequence Homology, Spike Glycoprotein, Coronavirus, Viral Envelope Proteins (genetics), Viral Envelope Proteins (metabolism).
MESH :
- chemical , genetics : Codon, Membrane Proteins, Viral Envelope Proteins.
- chemical , metabolism : Membrane Glycoproteins, Membrane Proteins, Viral Envelope Proteins.
- genetics : SARS Virus.
- Amino Acid Sequence, Base Sequence, Cluster Analysis, Gene Components, Genome, Viral, Molecular Sequence Data, Phylogeny, Protein Conformation, Sequence Alignment, Sequence Analysis, DNA, Sequence Homology, Spike Glycoprotein, Coronavirus.

Abstract

The E (envelope) protein is the smallest structural protein in all coronaviruses and is the only viral structural protein in which no variation has been detected. We conducted genome sequencing and phylogenetic analyses of SARS-CoV. Based on genome sequencing, we predicted the E protein is a transmembrane (TM) protein characterized by a TM region with strong hydrophobicity and alpha-helix conformation. We identified a segment (NH2-_L-Cys-A-Y-Cys-Cys-N_-COOH) in the carboxyl-terminal region of the E protein that appears to form three disulfide bonds with another segment of corresponding cysteines in the carboxyl-terminus of the S (spike) protein. These bonds point to a possible structural association between the E and S proteins. Our phylogenetic analyses of the E protein sequences in all published coronaviruses place SARS-CoV in an independent group in Coronaviridae and suggest a non-human animal origin.

DOI: 10.1016/s1672-0229(03)01017-9
PubMed: 15626343

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Le document en format XML

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<front><div type="abstract" xml:lang="en">The E (envelope) protein is the smallest structural protein in all coronaviruses and is the only viral structural protein in which no variation has been detected. We conducted genome sequencing and phylogenetic analyses of SARS-CoV. Based on genome sequencing, we predicted the E protein is a transmembrane (TM) protein characterized by a TM region with strong hydrophobicity and alpha-helix conformation. We identified a segment (NH2-_L-Cys-A-Y-Cys-Cys-N_-COOH) in the carboxyl-terminal region of the E protein that appears to form three disulfide bonds with another segment of corresponding cysteines in the carboxyl-terminus of the S (spike) protein. These bonds point to a possible structural association between the E and S proteins. Our phylogenetic analyses of the E protein sequences in all published coronaviruses place SARS-CoV in an independent group in Coronaviridae and suggest a non-human animal origin.</div>
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<Abstract><AbstractText>The E (envelope) protein is the smallest structural protein in all coronaviruses and is the only viral structural protein in which no variation has been detected. We conducted genome sequencing and phylogenetic analyses of SARS-CoV. Based on genome sequencing, we predicted the E protein is a transmembrane (TM) protein characterized by a TM region with strong hydrophobicity and alpha-helix conformation. We identified a segment (NH2-_L-Cys-A-Y-Cys-Cys-N_-COOH) in the carboxyl-terminal region of the E protein that appears to form three disulfide bonds with another segment of corresponding cysteines in the carboxyl-terminus of the S (spike) protein. These bonds point to a possible structural association between the E and S proteins. Our phylogenetic analyses of the E protein sequences in all published coronaviruses place SARS-CoV in an independent group in Coronaviridae and suggest a non-human animal origin.</AbstractText>
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<ReferenceList><Reference><Citation>Microbiol Mol Biol Rev. 1998 Dec;62(4):1171-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9841669</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1948-51</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12748314</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2001 Jan 20;279(2):371-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11162792</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1998 Aug;72(8):6838-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9658133</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Mol Biol Cell. 1995 Oct;6(10):1315-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8573789</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2002 May;76(10):4987-99</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11967315</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Biol Chem. 2000 Sep 15;275(37):29011-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10887183</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1999 Sep;73(9):7853-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10438879</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2000 Mar;74(5):2333-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10666264</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1998 Oct;72(10):7885-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9733825</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Science. 2003 May 30;300(5624):1399-404</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12730501</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1998 Nov;72(11):8636-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9765403</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Lancet. 2003 May 24;361(9371):1779-85</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12781537</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2001 Mar 15;281(2):163-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11277690</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2002 Nov;76(22):11518-29</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12388713</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Chin Sci Bull. 2003;48(10):941-948</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32214698</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 1997 Jan 20;227(2):378-88</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9018137</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Science. 2003 May 30;300(5624):1394-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12730500</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1999 Sep;73(9):7607-18</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10438851</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 1992 Jun;188(2):666-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1316677</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1998 Dec;72(12):9628-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9811696</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2000 May;74(9):4319-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10756047</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
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The E protein is a multifunctional membrane protein of SARS-CoV.

The E protein is a multifunctional membrane protein of SARS-CoV.

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