Contribution of trafficking signals in the cytoplasmic tail of the infectious bronchitis virus spike protein to virus infection.
Identifieur interne : 002499 ( PubMed/Curation ); précédent : 002498; suivant : 002500Contribution of trafficking signals in the cytoplasmic tail of the infectious bronchitis virus spike protein to virus infection.
Auteurs : Soonjeon Youn [États-Unis] ; Ellen W. Collisson ; Carolyn E. MachamerSource :
- Journal of virology [ 0022-538X ] ; 2005.
Descripteurs français
- KwdFr :
- Animaux, Cellules Vero, Cellules géantes, Cytoplasme (métabolisme), Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (génétique), Glycoprotéines membranaires (métabolisme), Infections à coronavirus (virologie), Mutation, Protéines de l'enveloppe virale (génétique), Protéines de l'enveloppe virale (métabolisme), Réplication virale, Réticulum endoplasmique (métabolisme), Réticulum endoplasmique (virologie), Transduction du signal, Virus de la bronchite infectieuse (métabolisme), Virus de la bronchite infectieuse (physiologie).
- MESH :
- génétique : Glycoprotéines membranaires, Protéines de l'enveloppe virale.
- métabolisme : Cytoplasme, Glycoprotéines membranaires, Protéines de l'enveloppe virale, Réticulum endoplasmique, Virus de la bronchite infectieuse.
- physiologie : Virus de la bronchite infectieuse.
- virologie : Infections à coronavirus, Réticulum endoplasmique.
- Animaux, Cellules Vero, Cellules géantes, Glycoprotéine de spicule des coronavirus, Mutation, Réplication virale, Transduction du signal.
English descriptors
- KwdEn :
- Animals, Chlorocebus aethiops, Coronavirus Infections (virology), Cytoplasm (metabolism), Endoplasmic Reticulum (metabolism), Endoplasmic Reticulum (virology), Giant Cells, Infectious bronchitis virus (metabolism), Infectious bronchitis virus (physiology), Membrane Glycoproteins (genetics), Membrane Glycoproteins (metabolism), Mutation, Signal Transduction, Spike Glycoprotein, Coronavirus, Vero Cells, Viral Envelope Proteins (genetics), Viral Envelope Proteins (metabolism), Virus Replication.
- MESH :
- chemical , genetics : Membrane Glycoproteins, Viral Envelope Proteins.
- metabolism : Cytoplasm, Endoplasmic Reticulum, Infectious bronchitis virus, Membrane Glycoproteins, Viral Envelope Proteins.
- physiology : Infectious bronchitis virus.
- virology : Coronavirus Infections, Endoplasmic Reticulum.
- Animals, Chlorocebus aethiops, Giant Cells, Mutation, Signal Transduction, Spike Glycoprotein, Coronavirus, Vero Cells, Virus Replication.
Abstract
Coronavirus spike (S) proteins are responsible for binding and fusion with target cells and thus play an essential role in virus infection. Recently, we identified a dilysine endoplasmic reticulum (ER) retrieval signal and a tyrosine-based endocytosis signal in the cytoplasmic tail of the S protein of infectious bronchitis virus (IBV). Here, an infectious cDNA clone of IBV was used to address the importance of the S protein trafficking signals to virus infection. We constructed infectious cDNA clones lacking the ER retrieval signal, the endocytosis signal, or both. The virus lacking the ER retrieval signal was viable. However, this virus had a growth defect at late times postinfection and produced larger plaques than IBV. Further analysis confirmed that the mutant S protein trafficked though the secretory pathway faster than wild-type S protein. A more dramatic phenotype was obtained when the endocytosis signal was mutated. Recombinant viruses lacking the endocytosis signal (in combination with a mutated dilysine signal or alone) could not be recovered, even though transient syncytia were formed in transfected cells. Our results suggest that the endocytosis signal of IBV S is essential for productive virus infection.
DOI: 10.1128/JVI.79.21.13209-13217.2005
PubMed: 16227244
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002499
Links to Exploration step
pubmed:16227244Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Contribution of trafficking signals in the cytoplasmic tail of the infectious bronchitis virus spike protein to virus infection.</title>
<author><name sortKey="Youn, Soonjeon" sort="Youn, Soonjeon" uniqKey="Youn S" first="Soonjeon" last="Youn">Soonjeon Youn</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cell Biology, Johns Hopkins University School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Cell Biology, Johns Hopkins University School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Collisson, Ellen W" sort="Collisson, Ellen W" uniqKey="Collisson E" first="Ellen W" last="Collisson">Ellen W. Collisson</name>
</author>
<author><name sortKey="Machamer, Carolyn E" sort="Machamer, Carolyn E" uniqKey="Machamer C" first="Carolyn E" last="Machamer">Carolyn E. Machamer</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2005">2005</date>
<idno type="RBID">pubmed:16227244</idno>
<idno type="pmid">16227244</idno>
<idno type="doi">10.1128/JVI.79.21.13209-13217.2005</idno>
<idno type="wicri:Area/PubMed/Corpus">002499</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002499</idno>
<idno type="wicri:Area/PubMed/Curation">002499</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002499</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Contribution of trafficking signals in the cytoplasmic tail of the infectious bronchitis virus spike protein to virus infection.</title>
<author><name sortKey="Youn, Soonjeon" sort="Youn, Soonjeon" uniqKey="Youn S" first="Soonjeon" last="Youn">Soonjeon Youn</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cell Biology, Johns Hopkins University School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Cell Biology, Johns Hopkins University School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Collisson, Ellen W" sort="Collisson, Ellen W" uniqKey="Collisson E" first="Ellen W" last="Collisson">Ellen W. Collisson</name>
</author>
<author><name sortKey="Machamer, Carolyn E" sort="Machamer, Carolyn E" uniqKey="Machamer C" first="Carolyn E" last="Machamer">Carolyn E. Machamer</name>
</author>
</analytic>
<series><title level="j">Journal of virology</title>
<idno type="ISSN">0022-538X</idno>
<imprint><date when="2005" type="published">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Chlorocebus aethiops</term>
<term>Coronavirus Infections (virology)</term>
<term>Cytoplasm (metabolism)</term>
<term>Endoplasmic Reticulum (metabolism)</term>
<term>Endoplasmic Reticulum (virology)</term>
<term>Giant Cells</term>
<term>Infectious bronchitis virus (metabolism)</term>
<term>Infectious bronchitis virus (physiology)</term>
<term>Membrane Glycoproteins (genetics)</term>
<term>Membrane Glycoproteins (metabolism)</term>
<term>Mutation</term>
<term>Signal Transduction</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Vero Cells</term>
<term>Viral Envelope Proteins (genetics)</term>
<term>Viral Envelope Proteins (metabolism)</term>
<term>Virus Replication</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Cellules Vero</term>
<term>Cellules géantes</term>
<term>Cytoplasme (métabolisme)</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Glycoprotéines membranaires (génétique)</term>
<term>Glycoprotéines membranaires (métabolisme)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Mutation</term>
<term>Protéines de l'enveloppe virale (génétique)</term>
<term>Protéines de l'enveloppe virale (métabolisme)</term>
<term>Réplication virale</term>
<term>Réticulum endoplasmique (métabolisme)</term>
<term>Réticulum endoplasmique (virologie)</term>
<term>Transduction du signal</term>
<term>Virus de la bronchite infectieuse (métabolisme)</term>
<term>Virus de la bronchite infectieuse (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Membrane Glycoproteins</term>
<term>Viral Envelope Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Glycoprotéines membranaires</term>
<term>Protéines de l'enveloppe virale</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Cytoplasm</term>
<term>Endoplasmic Reticulum</term>
<term>Infectious bronchitis virus</term>
<term>Membrane Glycoproteins</term>
<term>Viral Envelope Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cytoplasme</term>
<term>Glycoprotéines membranaires</term>
<term>Protéines de l'enveloppe virale</term>
<term>Réticulum endoplasmique</term>
<term>Virus de la bronchite infectieuse</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Virus de la bronchite infectieuse</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Infectious bronchitis virus</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Réticulum endoplasmique</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Endoplasmic Reticulum</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Chlorocebus aethiops</term>
<term>Giant Cells</term>
<term>Mutation</term>
<term>Signal Transduction</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Vero Cells</term>
<term>Virus Replication</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Cellules Vero</term>
<term>Cellules géantes</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Mutation</term>
<term>Réplication virale</term>
<term>Transduction du signal</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Coronavirus spike (S) proteins are responsible for binding and fusion with target cells and thus play an essential role in virus infection. Recently, we identified a dilysine endoplasmic reticulum (ER) retrieval signal and a tyrosine-based endocytosis signal in the cytoplasmic tail of the S protein of infectious bronchitis virus (IBV). Here, an infectious cDNA clone of IBV was used to address the importance of the S protein trafficking signals to virus infection. We constructed infectious cDNA clones lacking the ER retrieval signal, the endocytosis signal, or both. The virus lacking the ER retrieval signal was viable. However, this virus had a growth defect at late times postinfection and produced larger plaques than IBV. Further analysis confirmed that the mutant S protein trafficked though the secretory pathway faster than wild-type S protein. A more dramatic phenotype was obtained when the endocytosis signal was mutated. Recombinant viruses lacking the endocytosis signal (in combination with a mutated dilysine signal or alone) could not be recovered, even though transient syncytia were formed in transfected cells. Our results suggest that the endocytosis signal of IBV S is essential for productive virus infection.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16227244</PMID>
<DateCompleted><Year>2005</Year>
<Month>11</Month>
<Day>15</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-538X</ISSN>
<JournalIssue CitedMedium="Print"><Volume>79</Volume>
<Issue>21</Issue>
<PubDate><Year>2005</Year>
<Month>Nov</Month>
</PubDate>
</JournalIssue>
<Title>Journal of virology</Title>
<ISOAbbreviation>J. Virol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Contribution of trafficking signals in the cytoplasmic tail of the infectious bronchitis virus spike protein to virus infection.</ArticleTitle>
<Pagination><MedlinePgn>13209-17</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Coronavirus spike (S) proteins are responsible for binding and fusion with target cells and thus play an essential role in virus infection. Recently, we identified a dilysine endoplasmic reticulum (ER) retrieval signal and a tyrosine-based endocytosis signal in the cytoplasmic tail of the S protein of infectious bronchitis virus (IBV). Here, an infectious cDNA clone of IBV was used to address the importance of the S protein trafficking signals to virus infection. We constructed infectious cDNA clones lacking the ER retrieval signal, the endocytosis signal, or both. The virus lacking the ER retrieval signal was viable. However, this virus had a growth defect at late times postinfection and produced larger plaques than IBV. Further analysis confirmed that the mutant S protein trafficked though the secretory pathway faster than wild-type S protein. A more dramatic phenotype was obtained when the endocytosis signal was mutated. Recombinant viruses lacking the endocytosis signal (in combination with a mutated dilysine signal or alone) could not be recovered, even though transient syncytia were formed in transfected cells. Our results suggest that the endocytosis signal of IBV S is essential for productive virus infection.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Youn</LastName>
<ForeName>Soonjeon</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Cell Biology, Johns Hopkins University School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Collisson</LastName>
<ForeName>Ellen W</ForeName>
<Initials>EW</Initials>
</Author>
<Author ValidYN="Y"><LastName>Machamer</LastName>
<ForeName>Carolyn E</ForeName>
<Initials>CE</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>R01 GM064647</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>GM64647</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
<PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>J Virol</MedlineTA>
<NlmUniqueID>0113724</NlmUniqueID>
<ISSNLinking>0022-538X</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C578553">MHV surface projection glycoprotein</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D008562">Membrane Glycoproteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D064370">Spike Glycoprotein, Coronavirus</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014759">Viral Envelope Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C578557">spike glycoprotein, SARS-CoV</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002522" MajorTopicYN="N">Chlorocebus aethiops</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003593" MajorTopicYN="N">Cytoplasm</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004721" MajorTopicYN="N">Endoplasmic Reticulum</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015726" MajorTopicYN="N">Giant Cells</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001351" MajorTopicYN="N">Infectious bronchitis virus</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008562" MajorTopicYN="N">Membrane Glycoproteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009154" MajorTopicYN="N">Mutation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015398" MajorTopicYN="Y">Signal Transduction</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D064370" MajorTopicYN="N">Spike Glycoprotein, Coronavirus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014709" MajorTopicYN="N">Vero Cells</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014759" MajorTopicYN="N">Viral Envelope Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014779" MajorTopicYN="N">Virus Replication</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2005</Year>
<Month>10</Month>
<Day>18</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2005</Year>
<Month>11</Month>
<Day>16</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2005</Year>
<Month>10</Month>
<Day>18</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">16227244</ArticleId>
<ArticleId IdType="pii">79/21/13209</ArticleId>
<ArticleId IdType="doi">10.1128/JVI.79.21.13209-13217.2005</ArticleId>
<ArticleId IdType="pmc">PMC1262608</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>EMBO J. 1996 Apr 15;15(8):2020-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8617249</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Feb;79(4):2506-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15681451</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1997 Dec;71(12):9278-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9371586</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1998 Aug;72(8):6838-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9658133</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2000 May;74(9):4319-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10756047</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2000 Sep;74(17):8127-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10933723</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2001 Jan;75(1):278-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11119598</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2001 Jan 20;279(2):371-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11162792</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Traffic. 2000 Jul;1(7):525-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11208139</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2001 Nov;75(22):10787-99</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11602720</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2002 Nov;76(22):11518-29</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12388713</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2003 Apr;77(8):4597-608</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12663766</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2003 May;77(9):5192-200</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12692221</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2003 May 30;300(5624):1377-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12775826</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2003 Jul 20;312(1):25-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12890618</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Biochem. 2003;72:395-447</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12651740</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Jan;78(2):980-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14694129</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Feb;78(3):1552-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14722309</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Microbiol. 2003 Dec;1(3):209-18</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15035025</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Jun;78(11):5913-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15140989</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2004 Jun 20;324(1):173-83</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15183064</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1982 Aug;121(1):168-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6180551</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1986 Nov;83(21):8122-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3095828</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Cell Biol. 1987 Sep;105(3):1205-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2821010</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Top Microbiol Immunol. 1991;169:161-79</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1935227</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Cell Biol. 1992 Mar;116(5):1071-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1740466</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Cell Biol. 1994 Jan;124(1-2):55-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8294506</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1994 Oct;68(10):6523-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8083990</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 1995 Jul 1;155(1):473-88</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7602119</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Cell Biol. 1995 Oct;131(2):339-49</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7593163</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Virol. 1995;140(12):2201-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8572941</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Cell Biol. 1996 Mar;132(5):795-811</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8603913</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12056-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10518575</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Top Microbiol Immunol. 2005;287:31-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15609508</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2005 Feb 5;332(1):206-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15661153</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Adv Virus Res. 1997;48:1-100</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9233431</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002499 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 002499 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:16227244 |texte= Contribution of trafficking signals in the cytoplasmic tail of the infectious bronchitis virus spike protein to virus infection. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:16227244" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |