SrasV1, PubMed, Curation, bibRecord, 002382

Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.

Identifieur interne : 002382 ( PubMed/Curation ); précédent : 002381; suivant : 002383

Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.

Auteurs : Noah Butler [États-Unis] ; Lecia Pewe ; Kathryn Trandem ; Stanley Perlman

Source :

Virology [ 0042-6822 ] ; 2006.

RBID : pubmed:16413043

Descripteurs français

KwdFr :
- Animaux, Coronavirus humain OC43 (pathogénicité), Encéphalite virale (anatomopathologie), Encéphalite virale (mortalité), Encéphalite virale (médecine vétérinaire), Encéphalite virale (virologie), Humains, Infections à coronavirus (médecine vétérinaire), Infections à coronavirus (physiopathologie), Infections à coronavirus (virologie), Lignée cellulaire, Moelle spinale (anatomopathologie), Souris, Souris de lignée C57BL, Spécificité d'espèce.
MESH :
- anatomopathologie : Encéphalite virale, Moelle spinale.
- mortalité : Encéphalite virale.
- médecine vétérinaire : Encéphalite virale, Infections à coronavirus.
- pathogénicité : Coronavirus humain OC43.
- physiopathologie : Infections à coronavirus.
- virologie : Encéphalite virale, Infections à coronavirus.
- Animaux, Humains, Lignée cellulaire, Souris, Souris de lignée C57BL, Spécificité d'espèce.

English descriptors

KwdEn :
- Animals, Cell Line, Coronavirus Infections (physiopathology), Coronavirus Infections (veterinary), Coronavirus Infections (virology), Coronavirus OC43, Human (pathogenicity), Encephalitis, Viral (mortality), Encephalitis, Viral (pathology), Encephalitis, Viral (veterinary), Encephalitis, Viral (virology), Humans, Mice, Mice, Inbred C57BL, Species Specificity, Spinal Cord (pathology).
MESH :
- mortality : Encephalitis, Viral.
- pathogenicity : Coronavirus OC43, Human.
- pathology : Encephalitis, Viral, Spinal Cord.
- physiopathology : Coronavirus Infections.
- veterinary : Coronavirus Infections, Encephalitis, Viral.
- virology : Coronavirus Infections, Encephalitis, Viral.
- Animals, Cell Line, Humans, Mice, Mice, Inbred C57BL, Species Specificity.

Abstract

The human coronavirus HCoV-OC43 causes a significant fraction of upper respiratory tract infections. Most coronaviruses show a strong species specificity, although the SARS-Coronavirus crossed species from palm civet cats to infect humans. Similarly, HCoV-OC43, likely a member of the same coronavirus group as SARS-CoV, readily crossed the species barrier as evidenced by its rapid adaptation to the murine brain [McIntosh, K., Becker, W.B., Chanock, R.M., 1967. Growth in suckling-mouse brain of "IBV-like" viruses from patients with upper respiratory tract disease. Proc Natl Acad Sci U.S.A. 58, 2268-73]. Herein, we investigated two consequences of this plasticity in species tropism. First, we showed that HCoV-OC43 was able to infect cells from a large number of mammalian species. Second, we showed that virus that was passed exclusively in suckling mouse brains was highly virulent and caused a uniformly fatal encephalitis in adult mice. The surface glycoprotein is a major virulence factor in most coronavirus infections. We identified three changes in the HCoV-OC43 surface glycoprotein that correlated with enhanced neurovirulence in mice; these were located in the domain of the protein responsible for binding to host cells. These data suggest that some coronaviruses, including HCoV-OC43 and SARS-CoV, readily adapt to growth in cells from heterologous species. This adaptability has facilitated the isolation of HCoV-OC43 viral variants with markedly differing abilities to infect animals and tissue culture cells.

DOI: 10.1016/j.virol.2005.11.044
PubMed: 16413043

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002382

Links to Exploration step

pubmed:16413043

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.</title>
<author><name sortKey="Butler, Noah" sort="Butler, Noah" uniqKey="Butler N" first="Noah" last="Butler">Noah Butler</name>
<affiliation wicri:level="1"><nlm:affiliation>Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pewe, Lecia" sort="Pewe, Lecia" uniqKey="Pewe L" first="Lecia" last="Pewe">Lecia Pewe</name>
</author>
<author><name sortKey="Trandem, Kathryn" sort="Trandem, Kathryn" uniqKey="Trandem K" first="Kathryn" last="Trandem">Kathryn Trandem</name>
</author>
<author><name sortKey="Perlman, Stanley" sort="Perlman, Stanley" uniqKey="Perlman S" first="Stanley" last="Perlman">Stanley Perlman</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2006">2006</date>
<idno type="RBID">pubmed:16413043</idno>
<idno type="pmid">16413043</idno>
<idno type="doi">10.1016/j.virol.2005.11.044</idno>
<idno type="wicri:Area/PubMed/Corpus">002382</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002382</idno>
<idno type="wicri:Area/PubMed/Curation">002382</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002382</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.</title>
<author><name sortKey="Butler, Noah" sort="Butler, Noah" uniqKey="Butler N" first="Noah" last="Butler">Noah Butler</name>
<affiliation wicri:level="1"><nlm:affiliation>Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pewe, Lecia" sort="Pewe, Lecia" uniqKey="Pewe L" first="Lecia" last="Pewe">Lecia Pewe</name>
</author>
<author><name sortKey="Trandem, Kathryn" sort="Trandem, Kathryn" uniqKey="Trandem K" first="Kathryn" last="Trandem">Kathryn Trandem</name>
</author>
<author><name sortKey="Perlman, Stanley" sort="Perlman, Stanley" uniqKey="Perlman S" first="Stanley" last="Perlman">Stanley Perlman</name>
</author>
</analytic>
<series><title level="j">Virology</title>
<idno type="ISSN">0042-6822</idno>
<imprint><date when="2006" type="published">2006</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Cell Line</term>
<term>Coronavirus Infections (physiopathology)</term>
<term>Coronavirus Infections (veterinary)</term>
<term>Coronavirus Infections (virology)</term>
<term>Coronavirus OC43, Human (pathogenicity)</term>
<term>Encephalitis, Viral (mortality)</term>
<term>Encephalitis, Viral (pathology)</term>
<term>Encephalitis, Viral (veterinary)</term>
<term>Encephalitis, Viral (virology)</term>
<term>Humans</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Species Specificity</term>
<term>Spinal Cord (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Coronavirus humain OC43 (pathogénicité)</term>
<term>Encéphalite virale (anatomopathologie)</term>
<term>Encéphalite virale (mortalité)</term>
<term>Encéphalite virale (médecine vétérinaire)</term>
<term>Encéphalite virale (virologie)</term>
<term>Humains</term>
<term>Infections à coronavirus (médecine vétérinaire)</term>
<term>Infections à coronavirus (physiopathologie)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Lignée cellulaire</term>
<term>Moelle spinale (anatomopathologie)</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Spécificité d'espèce</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Encéphalite virale</term>
<term>Moelle spinale</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Encephalitis, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Encéphalite virale</term>
</keywords>
<keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Encéphalite virale</term>
<term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Coronavirus OC43, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Coronavirus humain OC43</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Encephalitis, Viral</term>
<term>Spinal Cord</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Coronavirus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Coronavirus Infections</term>
<term>Encephalitis, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Encéphalite virale</term>
<term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Encephalitis, Viral</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Cell Line</term>
<term>Humans</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Species Specificity</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Humains</term>
<term>Lignée cellulaire</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Spécificité d'espèce</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The human coronavirus HCoV-OC43 causes a significant fraction of upper respiratory tract infections. Most coronaviruses show a strong species specificity, although the SARS-Coronavirus crossed species from palm civet cats to infect humans. Similarly, HCoV-OC43, likely a member of the same coronavirus group as SARS-CoV, readily crossed the species barrier as evidenced by its rapid adaptation to the murine brain [McIntosh, K., Becker, W.B., Chanock, R.M., 1967. Growth in suckling-mouse brain of "IBV-like" viruses from patients with upper respiratory tract disease. Proc Natl Acad Sci U.S.A. 58, 2268-73]. Herein, we investigated two consequences of this plasticity in species tropism. First, we showed that HCoV-OC43 was able to infect cells from a large number of mammalian species. Second, we showed that virus that was passed exclusively in suckling mouse brains was highly virulent and caused a uniformly fatal encephalitis in adult mice. The surface glycoprotein is a major virulence factor in most coronavirus infections. We identified three changes in the HCoV-OC43 surface glycoprotein that correlated with enhanced neurovirulence in mice; these were located in the domain of the protein responsible for binding to host cells. These data suggest that some coronaviruses, including HCoV-OC43 and SARS-CoV, readily adapt to growth in cells from heterologous species. This adaptability has facilitated the isolation of HCoV-OC43 viral variants with markedly differing abilities to infect animals and tissue culture cells.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16413043</PMID>
<DateCompleted><Year>2006</Year>
<Month>11</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0042-6822</ISSN>
<JournalIssue CitedMedium="Print"><Volume>347</Volume>
<Issue>2</Issue>
<PubDate><Year>2006</Year>
<Month>Apr</Month>
<Day>10</Day>
</PubDate>
</JournalIssue>
<Title>Virology</Title>
<ISOAbbreviation>Virology</ISOAbbreviation>
</Journal>
<ArticleTitle>Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.</ArticleTitle>
<Pagination><MedlinePgn>410-21</MedlinePgn>
</Pagination>
<Abstract><AbstractText>The human coronavirus HCoV-OC43 causes a significant fraction of upper respiratory tract infections. Most coronaviruses show a strong species specificity, although the SARS-Coronavirus crossed species from palm civet cats to infect humans. Similarly, HCoV-OC43, likely a member of the same coronavirus group as SARS-CoV, readily crossed the species barrier as evidenced by its rapid adaptation to the murine brain [McIntosh, K., Becker, W.B., Chanock, R.M., 1967. Growth in suckling-mouse brain of "IBV-like" viruses from patients with upper respiratory tract disease. Proc Natl Acad Sci U.S.A. 58, 2268-73]. Herein, we investigated two consequences of this plasticity in species tropism. First, we showed that HCoV-OC43 was able to infect cells from a large number of mammalian species. Second, we showed that virus that was passed exclusively in suckling mouse brains was highly virulent and caused a uniformly fatal encephalitis in adult mice. The surface glycoprotein is a major virulence factor in most coronavirus infections. We identified three changes in the HCoV-OC43 surface glycoprotein that correlated with enhanced neurovirulence in mice; these were located in the domain of the protein responsible for binding to host cells. These data suggest that some coronaviruses, including HCoV-OC43 and SARS-CoV, readily adapt to growth in cells from heterologous species. This adaptability has facilitated the isolation of HCoV-OC43 viral variants with markedly differing abilities to infect animals and tissue culture cells.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Butler</LastName>
<ForeName>Noah</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pewe</LastName>
<ForeName>Lecia</ForeName>
<Initials>L</Initials>
</Author>
<Author ValidYN="Y"><LastName>Trandem</LastName>
<ForeName>Kathryn</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Perlman</LastName>
<ForeName>Stanley</ForeName>
<Initials>S</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>T32 GM007337</GrantID>
<Acronym>GM</Acronym>
<Agency>NIGMS NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2006</Year>
<Month>01</Month>
<Day>18</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Virology</MedlineTA>
<NlmUniqueID>0110674</NlmUniqueID>
<ISSNLinking>0042-6822</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002460" MajorTopicYN="N">Cell Line</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName UI="Q000662" MajorTopicYN="N">veterinary</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D028962" MajorTopicYN="N">Coronavirus OC43, Human</DescriptorName>
<QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018792" MajorTopicYN="N">Encephalitis, Viral</DescriptorName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000662" MajorTopicYN="Y">veterinary</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008810" MajorTopicYN="N">Mice, Inbred C57BL</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013045" MajorTopicYN="N">Species Specificity</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013116" MajorTopicYN="N">Spinal Cord</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2005</Year>
<Month>09</Month>
<Day>19</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2005</Year>
<Month>10</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2005</Year>
<Month>11</Month>
<Day>30</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2006</Year>
<Month>1</Month>
<Day>18</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2006</Year>
<Month>11</Month>
<Day>2</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2006</Year>
<Month>1</Month>
<Day>18</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">16413043</ArticleId>
<ArticleId IdType="pii">S0042-6822(05)00792-0</ArticleId>
<ArticleId IdType="doi">10.1016/j.virol.2005.11.044</ArticleId>
<ArticleId IdType="pmc">PMC7111823</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>J Exp Med. 1997 Jan 20;185(2):305-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9016879</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Gen Virol. 1993 Feb;74 ( Pt 2):183-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8381459</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 1993 Jul;195(1):195-202</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8317096</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 1967 Dec;58(6):2268-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">4298953</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nature. 2003 May 15;423(6937):240</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12748632</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 1999 Sep 15;163(6):3379-87</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10477608</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2005 Feb;79(3):1595-604</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15650185</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Gen Virol. 1993 Sep;74 ( Pt 9):1981-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8376972</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Lab Anim Sci. 1990 Sep;40(5):481-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2170746</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Science. 1995 Jul 28;269(5223):549-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7624779</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Adv Exp Med Biol. 2001;494:101-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11774452</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2003 Aug 1;312(2):369-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12919742</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Science. 2003 Oct 10;302(5643):276-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12958366</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Science. 2004 Mar 12;303(5664):1666-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14752165</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2001 Jan 20;279(2):371-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11162792</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1999 Sep;73(9):7752-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10438865</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1998 Sep;72(9):7349-56</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9696831</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nature. 2003 Nov 27;426(6965):450-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14647384</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Exp Med. 2005 Aug 1;202(3):415-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16043521</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Biochem Biophys Res Commun. 2003 Dec 26;312(4):1159-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14651994</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Exp Med. 1990 Oct 1;172(4):1127-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1698910</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1993 Mar;67(3):1195-202</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8437210</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15748-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15496474</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1967-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690091</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2002 Jul;76(14):7329-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12072531</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>EMBO J. 2005 Apr 20;24(8):1634-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15791205</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2002 Aug;76(16):8400-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12134043</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Arch Virol. 1981;67(4):367-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6263232</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 2000 Aug 15;165(4):2278-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10925317</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Eur J Immunol. 2000 Dec;30(12):3623-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11169405</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2004 Nov;78(21):12090-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15479853</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1997 Dec;71(12):9024-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9371559</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 1989 Jun;170(2):556-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2543129</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2005 Sep;79(17):11335-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16103185</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2001 Mar;75(6):3043-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11222733</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 1988 Jun;85(12):4526-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3380803</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Science. 2001 Jul 13;293(5528):303-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11452126</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Neuron. 1992 Jun;8(6):1185-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1610569</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8275-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15919828</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Arch Virol. 1996;141(6):1123-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8712929</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2005 May 10;335(2):185-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15840518</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nat Med. 2004 Apr;10(4):368-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15034574</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2005 Jan;79(2):884-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15613317</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Clin Infect Dis. 2003 Apr 15;36(8):985-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12684910</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2005 Sep;79(18):11892-900</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16140765</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1998 Sep;72(9):7357-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9696832</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 1985 May;54(2):429-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2985806</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 1991 Jul;183(1):397-404</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2053289</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 1998 Mar 15;160(6):2896-904</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9510193</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2003 Oct 10;315(1):20-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14592756</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2430-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15695582</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2004 Aug;78(16):8824-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15280490</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Virology. 2005 Jun 20;337(1):85-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15914223</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Immunol Invest. 1993 Mar;22(2):95-103</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8505072</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Gen Virol. 1992 Apr;73 ( Pt 4):901-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1321878</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nat Med. 2004 Dec;10(12 Suppl):S88-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15577937</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002382 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 002382 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    PubMed
   |étape=   Curation
   |type=    RBID
   |clé=     pubmed:16413043
   |texte=   Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i   -Sk "pubmed:16413043" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration SRAS

Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.

Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki