[Expression and significance of severe acute respiratory syndrome associated coronavirus (SARS-CoV)-X4 protein in lungs of SARS patients].
Identifieur interne : 002269 ( PubMed/Curation ); précédent : 002268; suivant : 002270[Expression and significance of severe acute respiratory syndrome associated coronavirus (SARS-CoV)-X4 protein in lungs of SARS patients].
Auteurs : Ya-Xia Tan [République populaire de Chine] ; Tao Chen ; Shu-Qing Zhong ; Yi-Min Li ; Ying-Yu Chen ; Xiao-Yan Qiu ; Xiao-Ning Mo ; Quan-Sheng Song ; Qi-Ni Gan ; Ying-Ying Gu ; Hong-Ying Mo ; Wei Luo ; Xin-Ming He ; Mu-Chang Liu ; Nan-Shan ZhongSource :
- Zhonghua nei ke za zhi [ 0578-1426 ] ; 2006.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Coloration et marquage, Humains, Immunohistochimie, Mâle, Poumon (anatomopathologie), Poumon (métabolisme), Protéines de la matrice virale (biosynthèse), Protéines virales (biosynthèse), Sujet âgé, Syndrome respiratoire aigu sévère (anatomopathologie), Syndrome respiratoire aigu sévère (métabolisme).
- MESH :
- anatomopathologie : Poumon, Syndrome respiratoire aigu sévère.
- biosynthèse : Protéines de la matrice virale, Protéines virales.
- métabolisme : Poumon, Syndrome respiratoire aigu sévère.
- Adulte, Adulte d'âge moyen, Coloration et marquage, Humains, Immunohistochimie, Mâle, Sujet âgé.
English descriptors
- KwdEn :
- MESH :
- chemical , biosynthesis : Viral Matrix Proteins, Viral Proteins.
- metabolism : Lung, Severe Acute Respiratory Syndrome.
- pathology : Lung, Severe Acute Respiratory Syndrome.
- Adult, Aged, Humans, Immunohistochemistry, Male, Middle Aged, Staining and Labeling.
Abstract
To investigate the significance of severe acute respiratory syndrome associated coronavirus (SARS-CoV)-X4 protein expression in lungs of patients with SARS.
PubMed: 16624149
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pubmed:16624149Le document en format XML
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last="Zhong">Shu-Qing Zhong</name></author><author><name sortKey="Li, Yi Min" sort="Li, Yi Min" uniqKey="Li Y" first="Yi-Min" last="Li">Yi-Min Li</name></author><author><name sortKey="Chen, Ying Yu" sort="Chen, Ying Yu" uniqKey="Chen Y" first="Ying-Yu" last="Chen">Ying-Yu Chen</name></author><author><name sortKey="Qiu, Xiao Yan" sort="Qiu, Xiao Yan" uniqKey="Qiu X" first="Xiao-Yan" last="Qiu">Xiao-Yan Qiu</name></author><author><name sortKey="Mo, Xiao Ning" sort="Mo, Xiao Ning" uniqKey="Mo X" first="Xiao-Ning" last="Mo">Xiao-Ning Mo</name></author><author><name sortKey="Song, Quan Sheng" sort="Song, Quan Sheng" uniqKey="Song Q" first="Quan-Sheng" last="Song">Quan-Sheng Song</name></author><author><name sortKey="Gan, Qi Ni" sort="Gan, Qi Ni" uniqKey="Gan Q" first="Qi-Ni" last="Gan">Qi-Ni Gan</name></author><author><name sortKey="Gu, Ying Ying" sort="Gu, Ying Ying" uniqKey="Gu Y" first="Ying-Ying" last="Gu">Ying-Ying Gu</name></author><author><name sortKey="Mo, Hong Ying" sort="Mo, Hong Ying" uniqKey="Mo H" first="Hong-Ying" last="Mo">Hong-Ying Mo</name></author><author><name sortKey="Luo, Wei" sort="Luo, Wei" uniqKey="Luo W" first="Wei" last="Luo">Wei Luo</name></author><author><name sortKey="He, Xin Ming" sort="He, Xin Ming" uniqKey="He X" first="Xin-Ming" last="He">Xin-Ming He</name></author><author><name sortKey="Liu, Mu Chang" sort="Liu, Mu Chang" uniqKey="Liu M" first="Mu-Chang" last="Liu">Mu-Chang Liu</name></author><author><name sortKey="Zhong, Nan Shan" sort="Zhong, Nan Shan" uniqKey="Zhong N" first="Nan-Shan" last="Zhong">Nan-Shan Zhong</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006</date><idno type="RBID">pubmed:16624149</idno><idno type="pmid">16624149</idno><idno type="wicri:Area/PubMed/Corpus">002269</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002269</idno><idno type="wicri:Area/PubMed/Curation">002269</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002269</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Expression and significance of severe acute respiratory syndrome associated coronavirus (SARS-CoV)-X4 protein in lungs of SARS patients].</title><author><name sortKey="Tan, Ya Xia" sort="Tan, Ya Xia" uniqKey="Tan Y" first="Ya-Xia" last="Tan">Ya-Xia Tan</name><affiliation wicri:level="1"><nlm:affiliation>Guangzhou Institute of Respiratory Disease, First Affiliated Hospital, Guangzhou Medical College, Guangzhou 510120, China. yaxiatan@yahoo.com.cn</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guangzhou Institute of Respiratory Disease, First Affiliated Hospital, Guangzhou Medical College, Guangzhou 510120</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Tao" sort="Chen, Tao" uniqKey="Chen T" first="Tao" last="Chen">Tao Chen</name></author><author><name sortKey="Zhong, Shu Qing" sort="Zhong, Shu Qing" uniqKey="Zhong S" first="Shu-Qing" last="Zhong">Shu-Qing Zhong</name></author><author><name sortKey="Li, Yi Min" sort="Li, Yi Min" uniqKey="Li Y" first="Yi-Min" last="Li">Yi-Min Li</name></author><author><name sortKey="Chen, Ying Yu" sort="Chen, Ying Yu" uniqKey="Chen Y" first="Ying-Yu" last="Chen">Ying-Yu Chen</name></author><author><name sortKey="Qiu, Xiao Yan" sort="Qiu, Xiao Yan" uniqKey="Qiu X" first="Xiao-Yan" last="Qiu">Xiao-Yan Qiu</name></author><author><name sortKey="Mo, Xiao Ning" sort="Mo, Xiao Ning" uniqKey="Mo X" first="Xiao-Ning" last="Mo">Xiao-Ning Mo</name></author><author><name sortKey="Song, Quan Sheng" sort="Song, Quan Sheng" uniqKey="Song Q" first="Quan-Sheng" last="Song">Quan-Sheng Song</name></author><author><name sortKey="Gan, Qi Ni" sort="Gan, Qi Ni" uniqKey="Gan Q" first="Qi-Ni" last="Gan">Qi-Ni Gan</name></author><author><name sortKey="Gu, Ying Ying" sort="Gu, Ying Ying" uniqKey="Gu Y" first="Ying-Ying" last="Gu">Ying-Ying Gu</name></author><author><name sortKey="Mo, Hong Ying" sort="Mo, Hong Ying" uniqKey="Mo H" first="Hong-Ying" last="Mo">Hong-Ying Mo</name></author><author><name sortKey="Luo, Wei" sort="Luo, Wei" uniqKey="Luo W" first="Wei" last="Luo">Wei Luo</name></author><author><name sortKey="He, Xin Ming" sort="He, Xin Ming" uniqKey="He X" first="Xin-Ming" last="He">Xin-Ming He</name></author><author><name sortKey="Liu, Mu Chang" sort="Liu, Mu Chang" uniqKey="Liu M" first="Mu-Chang" last="Liu">Mu-Chang Liu</name></author><author><name sortKey="Zhong, Nan Shan" sort="Zhong, Nan Shan" uniqKey="Zhong N" first="Nan-Shan" last="Zhong">Nan-Shan Zhong</name></author></analytic><series><title level="j">Zhonghua nei ke za zhi</title><idno type="ISSN">0578-1426</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Humans</term><term>Immunohistochemistry</term><term>Lung (metabolism)</term><term>Lung (pathology)</term><term>Male</term><term>Middle Aged</term><term>Severe Acute Respiratory Syndrome (metabolism)</term><term>Severe Acute Respiratory Syndrome (pathology)</term><term>Staining and Labeling</term><term>Viral Matrix Proteins (biosynthesis)</term><term>Viral Proteins (biosynthesis)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Coloration et marquage</term><term>Humains</term><term>Immunohistochimie</term><term>Mâle</term><term>Poumon (anatomopathologie)</term><term>Poumon (métabolisme)</term><term>Protéines de la matrice virale (biosynthèse)</term><term>Protéines virales (biosynthèse)</term><term>Sujet âgé</term><term>Syndrome respiratoire aigu sévère (anatomopathologie)</term><term>Syndrome respiratoire aigu sévère (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Viral Matrix Proteins</term><term>Viral Proteins</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Poumon</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Protéines de la matrice virale</term><term>Protéines virales</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lung</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Poumon</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lung</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Humans</term><term>Immunohistochemistry</term><term>Male</term><term>Middle Aged</term><term>Staining and Labeling</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Coloration et marquage</term><term>Humains</term><term>Immunohistochimie</term><term>Mâle</term><term>Sujet âgé</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To investigate the significance of severe acute respiratory syndrome associated coronavirus (SARS-CoV)-X4 protein expression in lungs of patients with SARS.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16624149</PMID><DateCompleted><Year>2007</Year><Month>03</Month><Day>06</Day></DateCompleted><DateRevised><Year>2014</Year><Month>02</Month><Day>26</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0578-1426</ISSN><JournalIssue CitedMedium="Print"><Volume>45</Volume><Issue>3</Issue><PubDate><Year>2006</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Zhonghua nei ke za zhi</Title><ISOAbbreviation>Zhonghua Nei Ke Za Zhi</ISOAbbreviation></Journal><ArticleTitle>[Expression and significance of severe acute respiratory syndrome associated coronavirus (SARS-CoV)-X4 protein in lungs of SARS patients].</ArticleTitle><Pagination><MedlinePgn>196-8</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To investigate the significance of severe acute respiratory syndrome associated coronavirus (SARS-CoV)-X4 protein expression in lungs of patients with SARS.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Pathological features of the lungs from 4 SARS patients were examined and the expression of SARS-CoV-X4 protein in the lungs was evaluated with immunohistochemical staining using specific antibodies against protein X4.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Microscopically, all lungs from 4 cases showed edema, erythrocyte and fibrin exudates in the alveoli, hyperplasia of alveolar epithelium, necrosis, hyaline membrane formation and fibroblast foci. Immunohistochemical stains showed a strong positivity of X4 protein in denudation cells, vascular endothelial cells and also erythrocytes and neutrophils in the alveoli of the lung tissues from the 4 cases.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Expression of SARS-CoV-X4 protein in the lungs may be involved in the pathogenesis and progression of SARS.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tan</LastName><ForeName>Ya-xia</ForeName><Initials>YX</Initials><AffiliationInfo><Affiliation>Guangzhou Institute of Respiratory Disease, First Affiliated Hospital, Guangzhou Medical College, Guangzhou 510120, China. yaxiatan@yahoo.com.cn</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Tao</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Zhong</LastName><ForeName>Shu-qing</ForeName><Initials>SQ</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Yi-min</ForeName><Initials>YM</Initials></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Ying-yu</ForeName><Initials>YY</Initials></Author><Author ValidYN="Y"><LastName>Qiu</LastName><ForeName>Xiao-yan</ForeName><Initials>XY</Initials></Author><Author ValidYN="Y"><LastName>Mo</LastName><ForeName>Xiao-ning</ForeName><Initials>XN</Initials></Author><Author ValidYN="Y"><LastName>Song</LastName><ForeName>Quan-sheng</ForeName><Initials>QS</Initials></Author><Author ValidYN="Y"><LastName>Gan</LastName><ForeName>Qi-ni</ForeName><Initials>QN</Initials></Author><Author ValidYN="Y"><LastName>Gu</LastName><ForeName>Ying-ying</ForeName><Initials>YY</Initials></Author><Author ValidYN="Y"><LastName>Mo</LastName><ForeName>Hong-ying</ForeName><Initials>HY</Initials></Author><Author ValidYN="Y"><LastName>Luo</LastName><ForeName>Wei</ForeName><Initials>W</Initials></Author><Author ValidYN="Y"><LastName>He</LastName><ForeName>Xin-ming</ForeName><Initials>XM</Initials></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Mu-chang</ForeName><Initials>MC</Initials></Author><Author ValidYN="Y"><LastName>Zhong</LastName><ForeName>Nan-shan</ForeName><Initials>NS</Initials></Author></AuthorList><Language>chi</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>China</Country><MedlineTA>Zhonghua Nei Ke Za Zhi</MedlineTA><NlmUniqueID>16210490R</NlmUniqueID><ISSNLinking>0578-1426</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014763">Viral Matrix Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014764">Viral Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C488151">sars7a protein, SARS virus</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007150" MajorTopicYN="N">Immunohistochemistry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013194" MajorTopicYN="N">Staining and Labeling</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014763" MajorTopicYN="N">Viral Matrix Proteins</DescriptorName><QualifierName UI="Q000096" MajorTopicYN="Y">biosynthesis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014764" MajorTopicYN="N">Viral Proteins</DescriptorName><QualifierName UI="Q000096" MajorTopicYN="Y">biosynthesis</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2006</Year><Month>4</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2007</Year><Month>3</Month><Day>7</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2006</Year><Month>4</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">16624149</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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