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Prevalence of subclinical infection and transmission of severe acute respiratory syndrome (SARS) in a residential care home for the elderly.

Identifieur interne : 002208 ( PubMed/Curation ); précédent : 002207; suivant : 002209

Prevalence of subclinical infection and transmission of severe acute respiratory syndrome (SARS) in a residential care home for the elderly.

Auteurs : L C L. Heung [Hong Kong] ; T. Li ; S K Mak ; W M Chan

Source :

RBID : pubmed:16760548

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Abstract

To ascertain the prevalence of subclinical severe acute respiratory syndrome-coronavirus (SARS-CoV) infection and study the transmission of SARS-CoV in a local outbreak at a residential care home for the elderly.

PubMed: 16760548

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pubmed:16760548

Le document en format XML

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<title xml:lang="en">Prevalence of subclinical infection and transmission of severe acute respiratory syndrome (SARS) in a residential care home for the elderly.</title>
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<name sortKey="Heung, L C L" sort="Heung, L C L" uniqKey="Heung L" first="L C L" last="Heung">L C L. Heung</name>
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<nlm:affiliation>Elderly Health Services, Department of Health, 35/F Hopewell Centre, 183 Queen's Road East, Wanchai, Hong Kong. lilyheung@ekit.com</nlm:affiliation>
<country xml:lang="fr">Hong Kong</country>
<wicri:regionArea>Elderly Health Services, Department of Health, 35/F Hopewell Centre, 183 Queen's Road East, Wanchai</wicri:regionArea>
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<name sortKey="Li, T" sort="Li, T" uniqKey="Li T" first="T" last="Li">T. Li</name>
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<name sortKey="Mak, S K" sort="Mak, S K" uniqKey="Mak S" first="S K" last="Mak">S K Mak</name>
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<name sortKey="Chan, W M" sort="Chan, W M" uniqKey="Chan W" first="W M" last="Chan">W M Chan</name>
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<name sortKey="Heung, L C L" sort="Heung, L C L" uniqKey="Heung L" first="L C L" last="Heung">L C L. Heung</name>
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<term>Antibodies, Viral (blood)</term>
<term>Contact Tracing</term>
<term>Coronavirus (immunology)</term>
<term>Coronavirus (isolation & purification)</term>
<term>Cross-Sectional Studies</term>
<term>Disease Outbreaks</term>
<term>Female</term>
<term>Health Personnel</term>
<term>Homes for the Aged</term>
<term>Hong Kong (epidemiology)</term>
<term>Humans</term>
<term>Infectious Disease Transmission, Patient-to-Professional</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prevalence</term>
<term>Seroepidemiologic Studies</term>
<term>Severe Acute Respiratory Syndrome (epidemiology)</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
<term>Severe Acute Respiratory Syndrome (transmission)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Anticorps antiviraux (sang)</term>
<term>Coronavirus (immunologie)</term>
<term>Coronavirus (isolement et purification)</term>
<term>Femelle</term>
<term>Flambées de maladies</term>
<term>Foyers pour personnes agées</term>
<term>Hong Kong (épidémiologie)</term>
<term>Humains</term>
<term>Mâle</term>
<term>Personnel de santé</term>
<term>Prévalence</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Syndrome respiratoire aigu sévère (immunologie)</term>
<term>Syndrome respiratoire aigu sévère (transmission)</term>
<term>Syndrome respiratoire aigu sévère (épidémiologie)</term>
<term>Transmission de maladie infectieuse du patient au professionnel de santé</term>
<term>Traçage des contacts</term>
<term>Études séroépidémiologiques</term>
<term>Études transversales</term>
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<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en">
<term>Antibodies, Viral</term>
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<term>Hong Kong</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr">
<term>Coronavirus</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en">
<term>Coronavirus</term>
<term>Severe Acute Respiratory Syndrome</term>
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<term>Coronavirus</term>
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<term>Anticorps antiviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en">
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Hong Kong</term>
<term>Syndrome respiratoire aigu sévère</term>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Contact Tracing</term>
<term>Cross-Sectional Studies</term>
<term>Disease Outbreaks</term>
<term>Female</term>
<term>Health Personnel</term>
<term>Homes for the Aged</term>
<term>Humans</term>
<term>Infectious Disease Transmission, Patient-to-Professional</term>
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<term>Prevalence</term>
<term>Seroepidemiologic Studies</term>
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<term>Foyers pour personnes agées</term>
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<front>
<div type="abstract" xml:lang="en">To ascertain the prevalence of subclinical severe acute respiratory syndrome-coronavirus (SARS-CoV) infection and study the transmission of SARS-CoV in a local outbreak at a residential care home for the elderly.</div>
</front>
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<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">16760548</PMID>
<DateCompleted>
<Year>2007</Year>
<Month>10</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised>
<Year>2016</Year>
<Month>10</Month>
<Day>20</Day>
</DateRevised>
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<ISSN IssnType="Print">1024-2708</ISSN>
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<Volume>12</Volume>
<Issue>3</Issue>
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<Year>2006</Year>
<Month>Jun</Month>
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<Title>Hong Kong medical journal = Xianggang yi xue za zhi</Title>
<ISOAbbreviation>Hong Kong Med J</ISOAbbreviation>
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<ArticleTitle>Prevalence of subclinical infection and transmission of severe acute respiratory syndrome (SARS) in a residential care home for the elderly.</ArticleTitle>
<Pagination>
<MedlinePgn>201-7</MedlinePgn>
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<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To ascertain the prevalence of subclinical severe acute respiratory syndrome-coronavirus (SARS-CoV) infection and study the transmission of SARS-CoV in a local outbreak at a residential care home for the elderly.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Cross-sectional study.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">A residential care home for the elderly in Hong Kong with a local outbreak of SARS.</AbstractText>
<AbstractText Label="PARTICIPANTS" NlmCategory="METHODS">Residents and staff in the residential care home who had contact with three patients with SARS (residents A and B, and staff C).</AbstractText>
<AbstractText Label="MAIN OUTCOME MEASURES" NlmCategory="METHODS">Blood samples were tested for total antibodies to SARS-CoV by immunofluorescence antibody test. The transmission of SARS was elucidated based on information from standardised questionnaires, and records of investigation and surveillance by the Department of Health.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Among the 90 eligible residents, three died, one moved out, and 19 refused to participate. Of the 32 eligible staff, six refused to participate. None of the remaining 93 participants tested positive for antibody to SARS-CoV. Based on the chronological order, resident A might have transmitted infection to resident B and staff C. Sitting close to the bathroom doorway while resident A took a shower was the only contact of resident B with resident A. The only opportunity for staff C to have contact with body fluids/excreta of resident A was in the handling of rubbish from the resident's room.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Subclinical SARS-CoV infection was rare in a residential care home for the elderly with an outbreak of SARS. Nonetheless the close working and living conditions for staff and residents in such a home may facilitate transmission of SARS despite vigilant precautionary measures.</AbstractText>
</Abstract>
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