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Non-molecular-clock-like evolution following viral origins in homo sapiens.

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Non-molecular-clock-like evolution following viral origins in homo sapiens.

Auteurs : Wendy Mok [Canada] ; Kelly Seto ; Jon Stone

Source :

Evolutionary bioinformatics online [ 1176-9343 ] ; 2007.

RBID : pubmed:19461973

Abstract

Researchers routinely adopt molecular clock assumptions in conducting sequence analyses to estimate dates for viral origins in humans. We used computational methods to examine the extent to which this practice can result in inaccurate 'retrodiction.' Failing to account for dynamic molecular evolution can affect greatly estimating index case dates, resulting in an overestimated age for the SARS-CoV-human infection, for instance.

PubMed: 19461973

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Non-molecular-clock-like evolution following viral origins in homo sapiens.

Non-molecular-clock-like evolution following viral origins in homo sapiens.

Source :

Abstract

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Pour générer des pages wiki