Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immunodeficiency virus infection.
Identifieur interne : 001E38 ( PubMed/Curation ); précédent : 001E37; suivant : 001E39Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immunodeficiency virus infection.
Auteurs : Yae-Jean Kim [États-Unis] ; Michael Boeckh ; Janet A. EnglundSource :
- Seminars in respiratory and critical care medicine [ 1069-3424 ] ; 2007.
Descripteurs français
- KwdFr :
- Antiviraux (usage thérapeutique), Humains, Infections communautaires (), Infections communautaires (traitement médicamenteux), Infections de l'appareil respiratoire (), Infections de l'appareil respiratoire (traitement médicamenteux), Infections de l'appareil respiratoire (virologie), Infections opportunistes liées au SIDA (), Infections opportunistes liées au SIDA (immunologie), Infections opportunistes liées au SIDA (traitement médicamenteux), Lutte contre l'infection, Maladies virales (), Maladies virales (traitement médicamenteux), Sujet immunodéprimé, Transplantation d'organe (effets indésirables), Transplantation de cellules souches hématopoïétiques (effets indésirables), Vaccins antiviraux.
- MESH :
- effets indésirables : Transplantation d'organe, Transplantation de cellules souches hématopoïétiques.
- immunologie : Infections opportunistes liées au SIDA.
- traitement médicamenteux : Infections communautaires, Infections de l'appareil respiratoire, Infections opportunistes liées au SIDA, Maladies virales.
- usage thérapeutique : Antiviraux.
- virologie : Infections de l'appareil respiratoire.
- Humains, Infections communautaires, Infections de l'appareil respiratoire, Infections opportunistes liées au SIDA, Lutte contre l'infection, Maladies virales, Sujet immunodéprimé, Vaccins antiviraux.
English descriptors
- KwdEn :
- AIDS-Related Opportunistic Infections (drug therapy), AIDS-Related Opportunistic Infections (immunology), AIDS-Related Opportunistic Infections (prevention & control), Antiviral Agents (therapeutic use), Community-Acquired Infections (drug therapy), Community-Acquired Infections (prevention & control), Hematopoietic Stem Cell Transplantation (adverse effects), Humans, Immunocompromised Host, Infection Control, Organ Transplantation (adverse effects), Respiratory Tract Infections (drug therapy), Respiratory Tract Infections (prevention & control), Respiratory Tract Infections (virology), Viral Vaccines, Virus Diseases (drug therapy), Virus Diseases (prevention & control).
- MESH :
- chemical , therapeutic use : Antiviral Agents.
- adverse effects : Hematopoietic Stem Cell Transplantation, Organ Transplantation.
- drug therapy : AIDS-Related Opportunistic Infections, Community-Acquired Infections, Respiratory Tract Infections, Virus Diseases.
- immunology : AIDS-Related Opportunistic Infections.
- prevention & control : AIDS-Related Opportunistic Infections, Community-Acquired Infections, Respiratory Tract Infections, Virus Diseases.
- virology : Respiratory Tract Infections.
- Humans, Immunocompromised Host, Infection Control, Viral Vaccines.
Abstract
Infection is the leading cause of morbidity and mortality in immunocompromised patients such as hematopoietic/solid organ transplant recipients and individuals with human immunodeficiency virus. Community respiratory virus infections are increasingly recognized as a significant threat to these patients. This article reviews current information in the clinical field of community respiratory viruses, including several newly discovered respiratory viruses. Respiratory syncytial virus, influenza viruses, parainfluenza viruses, and adenoviruses cause the most serious disease in immunocompromised hosts, but other respiratory viruses are becoming increasingly appreciated as a cause of both upper and lower respiratory tract disease. The clinical impact of these new viruses, including human metapneumovirus, non-SARS human coronaviruses, and human bocavirus, is not yet clear. Modern molecular technology has made the discovery of new viruses possible; the use of these new technologies in direct patient care is not yet standard but is becoming increasingly utilized. Clinicians should appreciate the potential for the development of antiviral resistance to influenza antivirals in immunocompromised patients.
DOI: 10.1055/s-2007-976494
PubMed: 17458776
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pubmed:17458776Le document en format XML
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<term>Virus Diseases</term>
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<term>Infections opportunistes liées au SIDA</term>
<term>Maladies virales</term>
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<front><div type="abstract" xml:lang="en">Infection is the leading cause of morbidity and mortality in immunocompromised patients such as hematopoietic/solid organ transplant recipients and individuals with human immunodeficiency virus. Community respiratory virus infections are increasingly recognized as a significant threat to these patients. This article reviews current information in the clinical field of community respiratory viruses, including several newly discovered respiratory viruses. Respiratory syncytial virus, influenza viruses, parainfluenza viruses, and adenoviruses cause the most serious disease in immunocompromised hosts, but other respiratory viruses are becoming increasingly appreciated as a cause of both upper and lower respiratory tract disease. The clinical impact of these new viruses, including human metapneumovirus, non-SARS human coronaviruses, and human bocavirus, is not yet clear. Modern molecular technology has made the discovery of new viruses possible; the use of these new technologies in direct patient care is not yet standard but is becoming increasingly utilized. Clinicians should appreciate the potential for the development of antiviral resistance to influenza antivirals in immunocompromised patients.</div>
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