Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication.
Identifieur interne : 001A56 ( PubMed/Curation ); précédent : 001A55; suivant : 001A57Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication.
Auteurs : Ji'An Pan [République populaire de Chine] ; Xiaoxue Peng ; Yajing Gao ; Zhilin Li ; Xiaolu Lu ; Yingzhao Chen ; Musarat Ishaq ; Dan Liu ; Marta L. Dediego ; Luis Enjuanes ; Deyin GuoSource :
- PloS one [ 1932-6203 ] ; 2008.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Protéines virales.
- métabolisme : Protéines virales.
- physiologie : Protéines virales, Réplication virale, Virus du SRAS.
- Gènes rapporteurs, Génome viral, Liaison aux protéines, Techniques de double hybride, Transcription génétique.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : Viral Proteins.
- chemical , metabolism : Viral Proteins.
- physiology : SARS Virus, Viral Proteins, Virus Replication.
- Genes, Reporter, Genome, Viral, Protein Binding, Transcription, Genetic, Two-Hybrid System Techniques.
Abstract
Analyses of viral protein-protein interactions are an important step to understand viral protein functions and their underlying molecular mechanisms. In this study, we adopted a mammalian two-hybrid system to screen the genome-wide intraviral protein-protein interactions of SARS coronavirus (SARS-CoV) and therefrom revealed a number of novel interactions which could be partly confirmed by in vitro biochemical assays. Three pairs of the interactions identified were detected in both directions: non-structural protein (nsp) 10 and nsp14, nsp10 and nsp16, and nsp7 and nsp8. The interactions between the multifunctional nsp10 and nsp14 or nsp16, which are the unique proteins found in the members of Nidovirales with large RNA genomes including coronaviruses and toroviruses, may have important implication for the mechanisms of replication/transcription complex assembly and functions of these viruses. Using a SARS-CoV replicon expressing a luciferase reporter under the control of a transcription regulating sequence, it has been shown that several viral proteins (N, X and SUD domains of nsp3, and nsp12) provided in trans stimulated the replicon reporter activity, indicating that these proteins may regulate coronavirus replication and transcription. Collectively, our findings provide a basis and platform for further characterization of the functions and mechanisms of coronavirus proteins.
DOI: 10.1371/journal.pone.0003299
PubMed: 18827877
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pubmed:18827877Le document en format XML
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<front><div type="abstract" xml:lang="en">Analyses of viral protein-protein interactions are an important step to understand viral protein functions and their underlying molecular mechanisms. In this study, we adopted a mammalian two-hybrid system to screen the genome-wide intraviral protein-protein interactions of SARS coronavirus (SARS-CoV) and therefrom revealed a number of novel interactions which could be partly confirmed by in vitro biochemical assays. Three pairs of the interactions identified were detected in both directions: non-structural protein (nsp) 10 and nsp14, nsp10 and nsp16, and nsp7 and nsp8. The interactions between the multifunctional nsp10 and nsp14 or nsp16, which are the unique proteins found in the members of Nidovirales with large RNA genomes including coronaviruses and toroviruses, may have important implication for the mechanisms of replication/transcription complex assembly and functions of these viruses. Using a SARS-CoV replicon expressing a luciferase reporter under the control of a transcription regulating sequence, it has been shown that several viral proteins (N, X and SUD domains of nsp3, and nsp12) provided in trans stimulated the replicon reporter activity, indicating that these proteins may regulate coronavirus replication and transcription. Collectively, our findings provide a basis and platform for further characterization of the functions and mechanisms of coronavirus proteins.</div>
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<Abstract><AbstractText>Analyses of viral protein-protein interactions are an important step to understand viral protein functions and their underlying molecular mechanisms. In this study, we adopted a mammalian two-hybrid system to screen the genome-wide intraviral protein-protein interactions of SARS coronavirus (SARS-CoV) and therefrom revealed a number of novel interactions which could be partly confirmed by in vitro biochemical assays. Three pairs of the interactions identified were detected in both directions: non-structural protein (nsp) 10 and nsp14, nsp10 and nsp16, and nsp7 and nsp8. The interactions between the multifunctional nsp10 and nsp14 or nsp16, which are the unique proteins found in the members of Nidovirales with large RNA genomes including coronaviruses and toroviruses, may have important implication for the mechanisms of replication/transcription complex assembly and functions of these viruses. Using a SARS-CoV replicon expressing a luciferase reporter under the control of a transcription regulating sequence, it has been shown that several viral proteins (N, X and SUD domains of nsp3, and nsp12) provided in trans stimulated the replicon reporter activity, indicating that these proteins may regulate coronavirus replication and transcription. Collectively, our findings provide a basis and platform for further characterization of the functions and mechanisms of coronavirus proteins.</AbstractText>
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<ReferenceList><Reference><Citation>J Virol. 2007 Jun;81(12):6356-68</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17392363</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Jun;81(12):6700-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17409150</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Jul;81(13):7086-98</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17428870</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biochem Mol Biol. 2007 Sep 30;40(5):649-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17927896</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Nov;81(22):12135-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17804504</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Nov;81(22):12323-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17855519</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2008 Feb 8;283(6):3655-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18045871</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Res. 2008 May;133(2):136-48</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18255185</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2008 Jul 5;376(2):379-89</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18452964</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2003 Jun 13;113(6):701-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12809601</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2003 Sep;84(Pt 9):2305-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12917450</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Mol Biol. 2003 Aug 29;331(5):991-1004</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12927536</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2003 Oct 10;278(41):39578-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12917423</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12995-3000</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14569023</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13190-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14585926</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochem Biophys Res Commun. 2004 Apr 2;316(2):476-83</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15020242</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2004 Mar 16;101(11):3792-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15007178</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochem Biophys Res Commun. 2004 May 14;317(4):1030-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15094372</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Jun;78(11):5619-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15140959</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2004 Jun 4;279(23):24765-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15037623</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12694-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15304651</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genome Res. 2004 Oct;14(10B):2029-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15489322</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Nov;78(22):12218-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15507608</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Nov;78(22):12683-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15507657</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Genet. 1996 Jan;12(1):72-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8528255</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biotechniques. 1997 Feb;22(2):350-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9043710</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Dec;78(24):13600-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15564471</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Mar;79(5):3182-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15709039</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Genes. 2005 Jan;30(1):93-102</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15744567</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 May;79(9):5288-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15827143</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Jun;79(11):6620-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15890900</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2005 Sep 16;309(5742):1864-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16166518</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2005 Oct;86(Pt 10):2763-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16186230</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Oct;79(20):12721-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16188975</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Oct;79(20):12905-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16188992</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Nov;79(21):13399-411</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16227261</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Mol Biol. 2005 Nov 11;353(5):1106-17</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16216269</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Dec;79(23):14909-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16282490</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 Aug;80(15):7287-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16840309</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 Aug;80(16):7894-901</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16873246</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 Aug;80(16):7902-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16873247</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11892-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16882730</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12365-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16895992</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12885-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16912115</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Adv Exp Med Biol. 2006;581:149-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17037522</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Microbiol. 2006;60:211-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16712436</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 Nov;80(21):10900-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16928748</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 2006 Oct 18;25(20):4933-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17024178</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Aug;82(16):8071-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18417574</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Mol Med. 2005 Nov;5(7):677-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16305493</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Dec;79(24):15189-98</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16306590</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2006 Jan 13;311(5758):239-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16339411</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Struct Mol Biol. 2005 Nov;12(11):980-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16228002</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5108-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16549795</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5717-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16581910</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochem Biophys Res Commun. 2006 May 19;343(4):1201-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16580632</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 Jun;80(12):5927-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16731931</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2000 Feb 15;267(2):185-98</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10662614</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Gene. 2000 Jan 25;242(1-2):369-79</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10721731</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4879-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10781095</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2001 Apr;82(Pt 4):935-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11257200</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2001 May;75(10):4614-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11312331</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2003 May;77(9):5401-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12692242</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2003 May 30;300(5624):1399-404</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12730501</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2003 Jun 13;300(5626):1763-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12746549</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Cycle. 2006 Oct;5(20):2414-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17102613</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Jan;81(1):416-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17035307</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Jan;81(2):718-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17079322</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Jan;81(2):548-57</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17108024</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Feb;81(4):1701-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17108030</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Apr;81(8):3913-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17229691</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 May;81(10):5423-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17344286</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2007;2(5):e459</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17520018</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>
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