Low prevalence of human metapneumovirus and human bocavirus in adult immunocompromised high risk patients suspected to suffer from Pneumocystis pneumonia.
Identifieur interne : 001961 ( PubMed/Curation ); précédent : 001960; suivant : 001962Low prevalence of human metapneumovirus and human bocavirus in adult immunocompromised high risk patients suspected to suffer from Pneumocystis pneumonia.
Auteurs : Andreas Müller [Allemagne] ; Dennis Klinkenberg ; Jörg Vehreschild ; Oliver Cornely ; Ramona Liza Tillmann ; Caspar Franzen ; Arne Simon ; Oliver SchildgenSource :
- The Journal of infection [ 1532-2742 ] ; 2009.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Animaux, Bocavirus (isolement et purification), Comorbidité, Femelle, Humains, Infections à Paramyxoviridae (virologie), Infections à Paramyxoviridae (épidémiologie), Infections à Parvoviridae (virologie), Infections à Parvoviridae (épidémiologie), Liquide de lavage bronchoalvéolaire (virologie), Metapneumovirus (isolement et purification), Mâle, Pneumocystis carinii (isolement et purification), Pneumonie à Pneumocystis (), Prévalence, Sujet immunodéprimé, Virus de la grippe A (isolement et purification).
- MESH :
- isolement et purification : Bocavirus, Metapneumovirus, Pneumocystis carinii, Virus de la grippe A.
- virologie : Infections à Paramyxoviridae, Infections à Parvoviridae, Liquide de lavage bronchoalvéolaire.
- épidémiologie : Infections à Paramyxoviridae, Infections à Parvoviridae.
- Adulte, Adulte d'âge moyen, Animaux, Comorbidité, Femelle, Humains, Mâle, Pneumonie à Pneumocystis, Prévalence, Sujet immunodéprimé.
English descriptors
- KwdEn :
- Adult, Animals, Bocavirus (isolation & purification), Bronchoalveolar Lavage Fluid (virology), Comorbidity, Female, Humans, Immunocompromised Host, Influenza A virus (isolation & purification), Male, Metapneumovirus (isolation & purification), Middle Aged, Paramyxoviridae Infections (epidemiology), Paramyxoviridae Infections (virology), Parvoviridae Infections (epidemiology), Parvoviridae Infections (virology), Pneumocystis carinii (isolation & purification), Pneumonia, Pneumocystis (complications), Prevalence.
- MESH :
- complications : Pneumonia, Pneumocystis.
- epidemiology : Paramyxoviridae Infections, Parvoviridae Infections.
- isolation & purification : Bocavirus, Influenza A virus, Metapneumovirus, Pneumocystis carinii.
- virology : Bronchoalveolar Lavage Fluid, Paramyxoviridae Infections, Parvoviridae Infections.
- Adult, Animals, Comorbidity, Female, Humans, Immunocompromised Host, Male, Middle Aged, Prevalence.
Abstract
Novel respiratory viruses were discovered in the last years predominantly in children. Until now information on newly identified respiratory viruses in immunosuppressed adult patients is limited. Here we investigated immunocompromised adults with suspected Pneumocystis jirovecii pneumonia (PCP) for new respiratory viruses.
DOI: 10.1016/j.jinf.2009.01.004
PubMed: 19211148
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pubmed:19211148Le document en format XML
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<front><div type="abstract" xml:lang="en">Novel respiratory viruses were discovered in the last years predominantly in children. Until now information on newly identified respiratory viruses in immunosuppressed adult patients is limited. Here we investigated immunocompromised adults with suspected Pneumocystis jirovecii pneumonia (PCP) for new respiratory viruses.</div>
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<Month>04</Month>
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<Month>Mar</Month>
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<Title>The Journal of infection</Title>
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<ArticleTitle>Low prevalence of human metapneumovirus and human bocavirus in adult immunocompromised high risk patients suspected to suffer from Pneumocystis pneumonia.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Novel respiratory viruses were discovered in the last years predominantly in children. Until now information on newly identified respiratory viruses in immunosuppressed adult patients is limited. Here we investigated immunocompromised adults with suspected Pneumocystis jirovecii pneumonia (PCP) for new respiratory viruses.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Bronchoalveolar lavage (BAL) samples of 128 patients with atypical pneumonia (HIV-infected n=50, hematological malignancy n=51, immunosuppressive treatment n=27) were prospectively evaluated for P. jirovecii and retrospectively for new respiratory viruses (HMPV, HBoV, HCoV-NL63/SARS/HKU1).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">P. jirovecii was detected in 26/128, bacteria in 10, fungi in four, Influenza A in two patients. Novel respiratory viruses were found in only two/128 patients with hematological malignancy, of those one patient with HBoV-infection and one with HMPV-infection, respectively. No pathogens were detected in 82/128 patients. The one patient with detection of hMPV and clinical diagnosis of atypical pneumonia died of pulmonary failure.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Human bocavirus and human metapneumovirus are rarely involved in atypical pneumonia in immunocompromised adult patients with suspected PCP, but may contribute to severe respiratory failure.</AbstractText>
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<ForeName>Andreas</ForeName>
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<AffiliationInfo><Affiliation>Department of Pediatrics, University of Bonn, Bonn, Germany. a.mueller@ukb.uni-bonn.de</Affiliation>
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<Author ValidYN="Y"><LastName>Schildgen</LastName>
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